The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.
Vaccinia Virus Inhibits the Maturation of Human Dendritic Cells: A Novel Mechanism of Immune Evasion
Open accessAbstract
Vaccinia virus employs multiple mechanisms to evade the immune system, yet is highly immunogenic. We studied the interaction between vaccinia and human dendritic cells (DCs), potent APCs. DCs develop from precursor cells in two stages: an immature stage in which Ag uptake and processing occur, and a mature stage in which there is up-regulation of costimulatory and HLA molecules and efficient T cell activation. Vaccinia virus undergoes an abortive replication in both stages of DCs and induces apoptotic cell death. Furthermore, maturation of immature DCs and consequently T cell activation are inhibited. Obstruction of DC maturation may constitute a novel mechanism by which vaccinia attempts to evade the immune response.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Dendritic cells and the control of immunity
Banchereau, J., & Steinman, R. M. (1998) · Nature · doi:10.1038/32588 · Cited by 14,336
Self-citationVermes, I., Haanen, C., Steffens-Nakken, H., & Reutellingsperger, C. (1995) · Journal of Immunological Methods · doi:10.1016/0022-1759(95)00072-i · Cited by 5,410
Koopman, G., Reutelingsperger, C., Kuijten, G., Keehnen, R., Pals, S., & van Oers, M. (1994) · Blood · doi:10.1182/blood.v84.5.1415.1415 · Cited by 2,681
Sallusto, F., Cella, M., Danieli, C., & Lanzavecchia, A. (1995) · The Journal of experimental medicine · doi:10.1084/jem.182.2.389 · Cited by 2,500
Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs
Albert, M. L., Sauter, B., & Bhardwaj, N. (1998) · Nature · doi:10.1038/32183 · Cited by 2,349
Self-citationActivation of human dendritic cells through CD40 cross-linking.
Caux, C., Massacrier, C., Vanbervliet, B., Dubois, B., Van Kooten, C., Durand, I., & Banchereau, J. (1994) · The Journal of experimental medicine · doi:10.1084/jem.180.4.1263 · Cited by 1,317
Albert, M. L., Pearce, S. F. A., Francisco, L. M., Sauter, B., Roy, P., Silverstein, R. L., & Bhardwaj, N. (1998) · The Journal of Experimental Medicine · doi:10.1084/jem.188.7.1359 · Cited by 1,234
Self-citationWong, B. R., Josien, R., Lee, S. Y., Sauter, B., Li, H.-L., Steinman, R. M., & Choi, Y. (1997) · The Journal of Experimental Medicine · doi:10.1084/jem.186.12.2075 · Cited by 853
Self-citationMaturation Stages of Mouse Dendritic Cells in Growth Factor–dependent Long-Term Cultures
Winzler, C., Rovere, P., Rescigno, M., Granucci, F., Penna, G., Adorini, L., Zimmermann, V. S., Davoust, J., & Ricciardi-Castagnoli, P. (1997) · The Journal of Experimental Medicine · doi:10.1084/jem.185.2.317 · Cited by 849
Lymphoid dendritic cells are potent stimulators of the primary mixed leukocyte reaction in mice.
Steinman, R. M., & Witmer, M. D. (1978) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.75.10.5132 · Cited by 818
Self-citation
Cited by
McFadden, G. (2005) · Nature Reviews Microbiology · doi:10.1038/nrmicro1099 · Cited by 523
Toll-Like Receptor Ligands Directly Promote Activated CD4+ T Cell Survival
Gelman, A. E., Zhang, J., Choi, Y., & Turka, L. A. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.10.6065 · Cited by 386
Visualizing priming of virus-specific CD8+ T cells by infected dendritic cells in vivo
Norbury, C. C., Malide, D., Gibbs, J. S., Bennink, J. R., & Yewdell, J. W. (2002) · Nature Immunology · doi:10.1038/ni762 · Cited by 342
Infection of Human Dendritic Cells by Dengue Virus Causes Cell Maturation and Cytokine Production
Ho, L.-J., Wang, J.-J., Shaio, M.-F., Kao, C.-L., Chang, D.-M., Han, S.-W., & Lai, J.-H. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.3.1499 · Cited by 314
The CD83 molecule - an important immune checkpoint
Grosche, L., Knippertz, I., König, C., Royzman, D., Wild, A. B., Zinser, E., Sticht, H., Muller, Y. A., Steinkasserer, A., & Lechmann, M. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00721 · Cited by 138
Metadata
- Authors
- Engelmayer, J., Larsson, M., Subklewe, M., Chahroudi, A., Cox, W. I., Steinman, R. M., & Bhardwaj, N.
- Venue
- The Journal of Immunology
- Publisher
- Oxford University Press (OUP)
- Published
- 1999-12
- Volume
- 163
- Issue
- 12
- Pages
- 6762-6768
- ISSN
- 0022-1767 (ISSN-L)
- 1550-6606
- OpenAlex
- W2172039135
- Cited by
- 365
- References
- 41
- FWCI
- 7.09
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Vaccinia Virus Inhibits the Maturation of Human Dendritic Cells: A Novel Mechanism of Immune Evasion. https://app.cochat.ai/papers/10.4049/jimmunol.163.12.6762
- The paper
- Engelmayer, J., Larsson, M., Subklewe, M., Chahroudi, A., Cox, W. I., Steinman, R. M., & Bhardwaj, N. (1999). Vaccinia Virus Inhibits the Maturation of Human Dendritic Cells: A Novel Mechanism of Immune Evasion. The Journal of Immunology. https://doi.org/10.4049/jimmunol.163.12.6762
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
