Lacto- N -fucopentaose III Found on Schitosoma mansoni Egg Antigens Functions as Adjuvant for Proteins by Inducing Th2-Type Response

The B7 and CD28 receptor families

June, C. H., Bluestone, J. A., Nadler, L. M., & Thompson, C. B. (1994) · Immunology Today · doi:10.1016/0167-5699(94)90080-9 · Cited by 1,296 · see citing works

Selectin ligands.

Varki, A. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.16.7390 · Cited by 946 · see citing works

B70 antigen is a second ligand for CTLA-4 and CD28

Azuma, M., Ito, D., Yagita∥, H., Okumura, K., Phillips, J. H., Lanier, L. L., & Somoza, C. (1993) · Nature · doi:10.1038/366076a0 · Cited by 910 · see citing works

Interference with HIV-induced syncytium formation and viral infectivity by inhibitors of trimming glucosidase

Gruters, R. A., Neefjes, J., Tersmette, M., de Goede, R. E. Y., Tulp, A., Huisman, H. G., Miedema, F. F., & Ploegh, H. L. (1987) · Nature · doi:10.1038/330074a0 · Cited by 578 · see citing works

Egg deposition is the major stimulus for the production of Th2 cytokines in murine schistosomiasis mansoni

Grzych, J., Pearce, E. J., Cheever, A. W., Caulada-Benedetti, Z., Caspar, P., Heiny, S. R., Lewis, F. A., & Sher, A. (1991) · The Journal of Immunology · doi:10.4049/jimmunol.146.4.1322 · Cited by 542 · see citing works

Uptake of Pneumocystis carinii mediated by the macrophage mannose receptor

Ezekowitz, R. A. B., Williams, D., Koziel, H., Armstrong, M. Y. K., Warner, A., Richards, F. F., & Rose, R. M. (1991) · Nature · doi:10.1038/351155a0 · Cited by 447 · see citing works

Oligosaccharide-specific induction of interleukin 10 production by B220+ cells from schistosome-infected mice: a mechanism for regulation of CD4+ T-cell subsets

Velupillai, P., & Harn, D. A. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.1.18 · Cited by 299 · see citing works

A multivalent lacto-N-fucopentaose III-lysyllysine conjugate decompacts preimplantation mouse embryos, while the free oligosaccharide is ineffective.

Fenderson, B. A., Zehavi, U., & Hakomori, S. (1984) · The Journal of Experimental Medicine · doi:10.1084/jem.160.5.1591 · Cited by 286 · see citing works

The mannose receptor and other macrophage lectins

Stahl, P. D. (1992) · Current Opinion in Immunology · doi:10.1016/0952-7915(92)90123-v · Cited by 245 · see citing works

In interleukin‐4‐deficient mice, alum not only generates T helper 1 responses equivalent to Freund's complete adjuvant, but continues to induce T helper 2 cytokine production

Brewer, J. M., Conacher, M., Satoskar, A. R., Bluethmann, H., & Alexander, J. K. (1996) · European Journal of Immunology · doi:10.1002/eji.1830260915 · Cited by 232 · see citing works

Costimulation of T-cell growth

Liu, Y., & Linsley, P. S. (1992) · Current Opinion in Immunology · doi:10.1016/0952-7915(92)90075-p · Cited by 216 · see citing works

Induction of Th2 Responses and IgE Is Largely Due to Carbohydrates Functioning as Adjuvants on <i>Schistosoma mansoni</i> Egg Antigens

Okano, M., Satoskar, A. R., Nishizaki, K., Abe, M., & Harn, D. A. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.163.12.6712 · Cited by 206 · see citing works

The structure of a neural specific carbohydrate epitope of horseradish peroxidase recognized by anti-horseradish peroxidase antiserum

Kurosaka, A., Yano, A., Itoh, N., Kuroda, Y., Nakagawa, T., & Kawasaki, T. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)64302-2 · Cited by 202 · see citing works

Increased expression of sialyl-dimeric LeX antigen in liver metastases of human colorectal carcinoma.

Hoff, S. D., Matsushita, Y., Ota, D. M., Cleary, K. R., Yamori, T., Hakomori, S., & Irimura, T. (1989) · PubMed · Cited by 192 · see citing works

A Schistosoma mansoni epitope recognized by a protective monoclonal antibody is identical to the stage-specific embryonic antigen 1.

Ko, A. I., Dräger, U. C., & Harn, D. A. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.11.4159 · Cited by 123 · see citing works

Heparinase inhibitsneovascularization.

Sasisekharan, R., Moses, M. A., Nugent, M. A., Cooney, C. L., & Langer, R. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.4.1524 · Cited by 119 · see citing works

B-1 cell (CD5+B220+) outgrowth in murine schistosomiasis is genetically restricted and is largely due to activation by polylactosamine sugars

Velupillai, P., Secor, W. E., Hörauf, A., & Harn, D. A. (1997) · The Journal of Immunology · doi:10.4049/jimmunol.158.1.338 · Cited by 108 · see citing works

Milk Oligosaccharide Profiles by Reversed-Phase HPLC of Their Perbenzoylated Derivatives

Chaturvedi, P., Warren, C. D., Ruiz-Palacios, G. M., Pickering, L. K., & Newburg, D. S. (1997) · Analytical Biochemistry · doi:10.1006/abio.1997.2250 · Cited by 94 · see citing works

Switch of CD4+ T Cell Differentiation from Th2 to Th1 by Treatment with Cathepsin B Inhibitor in Experimental Leishmaniasis

Maekawa, Y., Himeno, K., Ishikawa, H. T., Hisaeda, H., Sakai, T., Dainichi, T., Asao, T., Good, R. A., & Katunuma, N. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.161.5.2120 · Cited by 92 · see citing works

Carbohydrate‐dependent, HLA class II‐restricted, human T cell response to the bee venom allergen phospholipase A2 in allergic patients

Dudler, T., Altmann, F., Carballido, J. M., & Blaser, K. (1995) · European Journal of Immunology · doi:10.1002/eji.1830250235 · Cited by 72 · see citing works

Characterization of mouse nasal lymphocytes isolated by enzymatic extraction with collagenase

Asanuma, H., Inaba, Y., Aizawa, C., Kurata, T., & Tamura, S. (1995) · Journal of Immunological Methods · doi:10.1016/0022-1759(95)00165-7 · Cited by 70 · see citing works

Strain‐dependent induction of allergic rhinitis without adjuvant in mice

Okano, M., Harn, D. A., Abe, M., Wang, M., Satoskar, A., Nishizaki, K., Masuda, Y., Okano, M., & Yoshino, T. (1999) · Allergy · doi:10.1034/j.1398-9995.1999.00063.x · Cited by 65 · see citing works

Requirement of CD28‐CD86 costimulation for allergen‐specific T cell proliferation and cytokine expression

van Neerven, R. J. J., van de Pol, M. A., van der Zee, J. S., Stiekema, Boer, D., & Kapsenberg (1998) · Clinical & Experimental Allergy · doi:10.1046/j.1365-2222.1998.00306.x · Cited by 63 · see citing works

Biology, biochemistry and immunology of carcinoma-associated mucins

Taylor‐Papadimitriou, J., & Finn, O. J. (1997) · Immunology Today · doi:10.1016/s0167-5699(97)01028-1 · Cited by 36 · see citing works

Immunology of parasitic diseases.

Haralambides, S. T. (1980) · Cited by 31 · see citing works

Involvement of carbohydrate on phospholipase A2, a bee‐venom allergen, in in vivo antigen‐specific IgE synthesis in mice

Okano, M., Satoskar, A., Harn, D. A., Nishizaki, K., Okano, M., Masuda, Y., & Yoshino, T. (1999) · Allergy · doi:10.1034/j.1398-9995.1999.00096.x · Cited by 30 · see citing works

IgE-selective and antigen-specific unresponsiveness in mice. I. Induction of the unresponsiveness by administration of ovalbumin-pullulan conjugate.

臼井, 美., & Matuhasi, T. (1979) · PubMed · Cited by 24 · see citing works

IgE-Selective and Antigen-Specific Unresponsiveness in Mice

臼井, 美., & Matuhasi, T. (1979) · The Journal of Immunology · doi:10.4049/jimmunol.122.4.1266 · Cited by 20 · see citing works

CD86 (B7–2) antigen on B cells from atopic patients shows selective, antigen‐specific upregulation

Nakada, M., Nishizaki, K., Yoshino, T., Okano, M., Masuda, Y., Ohta, N., & Akagi, T. (1998) · Allergy · doi:10.1111/j.1398-9995.1998.tb04091.x · Cited by 19 · see citing works

Dendritic-cell control of pathogen-driven T-cell polarization

Kapsenberg, M. L. (2003) · Nature reviews. Immunology · doi:10.1038/nri1246 · Cited by 1,440 · see citing works

The immunobiology of schistosomiasis

Pearce, E. J., & MacDonald, A. S. (2002) · Nature reviews. Immunology · doi:10.1038/nri843 · Cited by 1,151 · see citing works

Immune Regulation by helminth parasites: cellular and molecular mechanisms

Maizels, R. M., & Yazdanbakhsh, M. (2003) · Nature reviews. Immunology · doi:10.1038/nri1183 · Cited by 1,141 · see citing works

How are TH2-type immune responses initiated and amplified?

Paul, W. E., & Zhu, J. (2010) · Nature reviews. Immunology · doi:10.1038/nri2735 · Cited by 957 · see citing works

Helminth parasites – masters of regulation

Maizels, R. M., Balic, A., Gomez‐Escobar, N., Nair, M. G., Taylor, M. D., & Allen, J. E. (2004) · Immunological Reviews · doi:10.1111/j.0105-2896.2004.00191.x · Cited by 866 · see citing works

Modulation of Host Immunity by Helminths: The Expanding Repertoire of Parasite Effector Molecules

Maizels, R. M., Smits, H. H., & McSorley, H. J. (2018) · Immunity · doi:10.1016/j.immuni.2018.10.016 · Cited by 435 · see citing works

Parasites and the Hygiene Hypothesis: Regulating the Immune System?

Yazdanbakhsh, M., & Matricardi, P. M. (2004) · Clinical Reviews in Allergy & Immunology · doi:10.1385/criai:26:1:15 · Cited by 420 · see citing works

The Role of Protein Glycosylation in Allergy

Altmann, F. (2007) · International Archives of Allergy and Immunology · doi:10.1159/000096114 · Cited by 393 · see citing works

Control of adaptive immune responses by Toll-like receptors

Barton, G. M., & Medzhitov, R. M. (2002) · Current Opinion in Immunology · doi:10.1016/s0952-7915(02)00343-6 · Cited by 325 · see citing works

The dendritic cell-specific C-type lectin DC-SIGN is a receptor for Schistosoma mansoni egg antigens and recognizes the glycan antigen Lewis x

van Die, I. (2003) · Glycobiology · doi:10.1093/glycob/cwg052 · Cited by 316 · see citing works

Maturation of Dendritic Cell 2 Phenotype by a Helminth Glycan Uses a Toll-Like Receptor 4-Dependent Mechanism

Thomas, P. G., Carter, M. R., Atochina, O., Da’dara, A. A., Piskorska, D., McGuire, E., & Harn, D. A. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.171.11.5837 · Cited by 300 · see citing works

Alternatively activated macrophages during parasite infections

Noël, W. (2004) · Trends in Parasitology · doi:10.1016/j.pt.2004.01.004 · Cited by 300 · see citing works

Human Milk Oligosaccharides Influence Neonatal Mucosal and Systemic Immunity

Donovan, S. M., & Comstock, S. S. (2016) · Annals of Nutrition and Metabolism · doi:10.1159/000452818 · Cited by 293 · see citing works

The Major Glycoprotein Allergen from Arachis hypogaea, Ara h 1, Is a Ligand of Dendritic Cell-Specific ICAM-Grabbing Nonintegrin and Acts as a Th2 Adjuvant In Vitro

Shreffler, W. G., Castro, R., Kucuk, Z. Y., Charlop–Powers, Z., Grishina, G. T., Yoo, S., Burks, A. W., & Sampson, H. A. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.6.3677 · Cited by 268 · see citing works

Schistosoma mansoni soluble egg antigens are internalized by human dendritic cells through multiple C-type lectins and suppress TLR-induced dendritic cell activation

van Liempt, E., van Vliet, S. J., Engering, A. J., García-Vallejo, J. J., Bank, C. M. C., Sánchez‐Hernández, M., van Kooyk, Y., & van Die, I. (2007) · Molecular Immunology · doi:10.1016/j.molimm.2006.12.012 · Cited by 255 · see citing works

Dectin-2 Recognition of House Dust Mite Triggers Cysteinyl Leukotriene Generation by Dendritic Cells

Barrett, N. A., Maekawa, A., Rahman, O. M., Austen, K. F., & Kanaoka, Y. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.182.2.1119 · Cited by 247 · see citing works

The immune response to parasitic helminths: insights from murine models

Gause, W. C. (2003) · Trends in Immunology · doi:10.1016/s1471-4906(03)00101-7 · Cited by 247 · see citing works

Macrophage galactose-type C-type lectins as novel markers for alternatively activated macrophages elicited by parasitic infections and allergic airway inflammation

Raes, G., Brys, L., Dahal, B. K., Brandt, J., Grooten, J., Brombacher, F., Vanham, G., Noël, W., Bogaert, P., Boonefaes, T., et al. (2004) · Journal of Leukocyte Biology · doi:10.1189/jlb.0304212 · Cited by 246 · see citing works

Prebiotic oligosaccharides: In vitro evidence for gastrointestinal epithelial transfer and immunomodulatory properties

Eiwegger, T., Stahl, B., Haidl, P., Schmitt, J., Boehm, G., Dehlink, E., Urbanek, R., & Szépfalusi, Z. (2010) · Pediatric Allergy and Immunology · doi:10.1111/j.1399-3038.2010.01062.x · Cited by 246 · see citing works

A worm's eye view of the immune system: consequences for evolution of human autoimmune disease

Dunne, D. W., & Cooke, A. (2005) · Nature reviews. Immunology · doi:10.1038/nri1601 · Cited by 245 · see citing works

Glycan gimmickry by parasitic helminths: A strategy for modulating the host immune response?

van Die, I., & Cummings, R. D. (2010) · Glycobiology · doi:10.1093/glycob/cwp140 · Cited by 199 · see citing works

Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes

Barrett, N. A., Rahman, O. M., Fernandez, J. M., Parsons, M. W., Xing, W., Austen, K. F., & Kanaoka, Y. (2011) · Journal of Experimental Medicine · doi:10.1084/jem.20100793 · Cited by 211 · see citing works

Suppression of TH2-type allergic reactions by helminth infection

Fallon, P. G., & Mangan, N. E. (2007) · Nature reviews. Immunology · doi:10.1038/nri2039 · Cited by 192 · see citing works

Th2 response polarization during infection with the helminth parasite Schistosoma mansoni

Pearce, E. J., Kane, C. M., Sun, J., Taylor, J. J., McKee, A. S., & Cervi, L. (2004) · Immunological Reviews · doi:10.1111/j.0105-2896.2004.00187.x · Cited by 189 · see citing works

Parasitic worms and inflammatory diseases

Zaccone, P., Fehervari, Z. T., Phillips, J. M., Dunne, D. W., & Cooke, A. (2006) · Parasite Immunology · doi:10.1111/j.1365-3024.2006.00879.x · Cited by 187 · see citing works

Lewis X component in human milk binds DC-SIGN and inhibits HIV-1 transfer to CD4+ T lymphocytes

Naarding, M. A. (2005) · Journal of Clinical Investigation · doi:10.1172/jci25105 · Cited by 187 · see citing works

Molecular Characterization of an Interleukin-4-inducing Factor from Schistosoma mansoni Eggs

Schramm, G., Falcone, F. H., Gronow, A., Haisch, K., Mamat, U., Doenhoff, M. J., Oliveira, G., Galle, J., Dahinden, C. A., & Haas, H. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m300497200 · Cited by 178 · see citing works

Insights into the initiation of type 2 immune responses

Oliphant, C. J., Barlow, J. L., & McKenzie, A. N. J. (2011) · Immunology · doi:10.1111/j.1365-2567.2011.03499.x · Cited by 172 · see citing works

The Schistosome Oligosaccharide Lacto- <i>N</i> -neotetraose Expands Gr1+ Cells That Secrete Anti-inflammatory Cytokines and Inhibit Proliferation of Naive CD4+ Cells: A Potential Mechanism for Immune Polarization in Helminth Infections

Terrazas, L. I., Walsh, K. L., Piskorska, D., McGuire, E., & Harn, D. A. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.167.9.5294 · Cited by 169 · see citing works

Chronic Helminth Infections Protect Against Allergic Diseases by Active Regulatory Processes

Smits, H. H., Everts, B., Hartgers, F. C., & Yazdanbakhsh, M. (2010) · Current Allergy and Asthma Reports · doi:10.1007/s11882-009-0085-3 · Cited by 160 · see citing works

Human milk oligosaccharides: The role in the fine-tuning of innate immune responses

Kulinich, A. O., & Liu, L. (2016) · Carbohydrate Research · doi:10.1016/j.carres.2016.07.009 · Cited by 151 · see citing works

Survey of immune-related, mannose/fucose-binding C-type lectin receptors reveals widely divergent sugar-binding specificities

Lee, R. T., Hsu, T.-L., Huang, S. K., Hsieh, S.-L., Wong, C., & Lee, Y. C. (2010) · Glycobiology · doi:10.1093/glycob/cwq193 · Cited by 149 · see citing works

A Schistosome-Expressed Immunomodulatory Glycoconjugate Expands Peritoneal Gr1+ Macrophages That Suppress Naive CD4+ T Cell Proliferation Via an IFN-γ and Nitric Oxide-Dependent Mechanism

Atochina, O., Daly‐Engel, T. S., Piskorska, D., McGuire, E., & Harn, D. A. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.167.8.4293 · Cited by 144 · see citing works

Priming of the immune response by schistosome eggs

Pearce, E. J. (2005) · Parasite Immunology · doi:10.1111/j.1365-3024.2005.00765.x · Cited by 137 · see citing works

Immune biasing by helminth glycans

Thomas, P. G., & Harn, D. A. (2003) · Cellular Microbiology · doi:10.1046/j.1462-5822.2003.00337.x · Cited by 137 · see citing works

Anti-schistosomal Intervention Targets Identified by Lifecycle Transcriptomic Analyses

Fitzpatrick, J. M., Peak, E., Perally, S., Chalmers, I. W., Barrett, J., Yoshino, T. P., Ivens, A. C., & Hoffmann, K. F. (2009) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0000543 · Cited by 128 · see citing works

New insights into innate immune mechanisms underlying allergenicity

Wills-Karp, M. A., Nathan, A. T., Page, K., & Karp, C. L. (2009) · Mucosal Immunology · doi:10.1038/mi.2009.138 · Cited by 129 · see citing works

Elucidating the Mechanisms of Action of Saponin-Derived Adjuvants

Marciani, D. J. (2018) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2018.03.005 · Cited by 127 · see citing works

Both Free-Living and Parasitic Nematodes Induce a Characteristic Th2 Response That Is Dependent on the Presence of Intact Glycans

Tawill, S. A., Goff, L. L., Ali, F., Blaxter, M., & Allen, J. E. (2003) · Infection and Immunity · doi:10.1128/iai.72.1.398-407.2004 · Cited by 126 · see citing works

Cytokine-mediated host responses during schistosome infections; walking the fine line between immunological control and immunopathology

HOFFMANN, K., Wynn, T. A., & Dunne, D. W. (2002) · Advances in Parasitology/Advances in parasitology · doi:10.1016/s0065-308x(02)52014-5 · Cited by 124 · see citing works

Th2 responses in schistosomiasis

Fairfax, K. C., Nascimento, M., Huang, S. C., Everts, B., & Pearce, E. J. (2012) · Seminars in Immunopathology · doi:10.1007/s00281-012-0354-4 · Cited by 121 · see citing works

Glycomics Analysis of Schistosoma mansoni Egg and Cercarial Secretions*S

Jang-Lee, J., Curwen, R. S., Ashton, P. D., Tissot, B., Mathieson, W., Panico, M., Dell, A., Wilson, R. A., & Haslam, S. (2007) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m700004-mcp200 · Cited by 124 · see citing works

Helminths and dendritic cells: Sensing and regulating via pattern recognition receptors, Th2 and Treg responses

Everts, B., Smits, H. H., Hokke, C. H., & Yazdanbakhsh, M. (2010) · European Journal of Immunology · doi:10.1002/eji.200940109 · Cited by 119 · see citing works

Schistosome N‐glycans containing core α3‐fucose and core β2‐xylose epitopes are strong inducers of Th2 responses in mice

Faveeuw, C., Mallevaey, T., Paschinger, K., Wilson, I. B. H., Fontaine, J., Mollicone, R., Oriol, R., Altmann, F., Lerouge, P., Capron, M., et al. (2003) · European Journal of Immunology · doi:10.1002/eji.200323717 · Cited by 117 · see citing works

Shaping the immune response to parasites: role of dendritic cells

Sher, A., Pearce, E. J., & Kaye, P. M. (2003) · Current Opinion in Immunology · doi:10.1016/s0952-7915(03)00072-4 · Cited by 112 · see citing works

Soluble helminth products suppress clinical signs in murine experimental autoimmune encephalomyelitis and differentially modulate human dendritic cell activation

Kuijk, L. M., Klaver, E. J., Kooij, G., van der Pol, S. M. A., Heijnen, P. D. A. M., Bruijns, S. C. M., Kringel, H., Pinelli, E., Kraal, G., de Vries, H. E., et al. (2012) · Molecular Immunology · doi:10.1016/j.molimm.2012.03.020 · Cited by 105 · see citing works

Activation and regulation of Toll-Like Receptors (TLRs) by helminth parasites

Venugopal, P. G., Nutman, T. B., & Semnani, R. T. (2008) · Immunologic Research · doi:10.1007/s12026-008-8079-0 · Cited by 105 · see citing works

Molecular Basis of the Differences in Binding Properties of the Highly Related C-type Lectins DC-SIGN and L-SIGN to Lewis X Trisaccharide and Schistosoma mansoni Egg Antigens

van Liempt, E., Imberty, A., Bank, C. M. C., van Vliet, S. J., van Kooyk, Y., Geijtenbeek, T. B. H., & van Die, I. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m404988200 · Cited by 104 · see citing works

Trichuris suis-induced modulation of human dendritic cell function is glycan-mediated

Klaver, E. J., Kuijk, L. M., Laan, L. C., Kringel, H., van Vliet, S. J., Bouma, G., Cummings, R. D., Kraal, G., & van Die, I. (2012) · International Journal for Parasitology · doi:10.1016/j.ijpara.2012.10.021 · Cited by 103 · see citing works

IPSE/alpha-1: A major immunogenic component secreted from Schistosoma mansoni eggs

Schramm, G., Gronow, A., Knobloch, J., Wippersteg, V., Grevelding, C. G., Galle, J., Fuller, H. R., STANLEY, R. G., Chiodini, P. L., Haas, H., et al. (2006) · Molecular and Biochemical Parasitology · doi:10.1016/j.molbiopara.2006.01.003 · Cited by 102 · see citing works

DC-SIGN Mediates Binding of Dendritic Cells to Authentic Pseudo-LewisY Glycolipids of Schistosoma mansoni Cercariae, the First Parasite-specific Ligand of DC-SIGN

Meyer, S., van Liempt, E., Imberty, A., van Kooyk, Y., Geyer, H., Geyer, R., & van Die, I. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m507100200 · Cited by 102 · see citing works

Schistosome glycoconjugates in host-parasite interplay

Hokke, C. H., & Deelder, A. M. (2001) · Glycoconjugate Journal · doi:10.1023/a:1020634602161 · Cited by 101 · see citing works

Triggering of Innate Immune Responses by Schistosome Egg Glycolipids and Their Carbohydrate Epitope GalNAcβ1‐4(Fucα1‐2Fucα1‐3)GlcNAc

van der Kleij, D., van Remoortere, A., Schuitemaker, J. H. N., Kapsenberg, M. L., Deelder, A. M., Tielens, A. G. M., Hokke, C. H., & Yazdanbakhsh, M. (2002) · The Journal of Infectious Diseases · doi:10.1086/338574 · Cited by 98 · see citing works

Extracts of the Rat Tapeworm,Hymenolepis diminuta, Suppress Macrophage ActivationIn Vitroand Alleviate Chemically Induced Colitis in Mice

Johnston, M. J. G., Wang, A., Catarino, M., Ball, L., Phan, V. N., MacDonald, J. A., & McKay, D. M. (2009) · Infection and Immunity · doi:10.1128/iai.01349-08 · Cited by 92 · see citing works

Modulation of host immune responses by helminth glycans

Harn, D. A., McDonald, J. A., Atochina, O., & Da’dara, A. A. (2009) · Immunological Reviews · doi:10.1111/j.1600-065x.2009.00799.x · Cited by 88 · see citing works

Antigen Presentation by CD1d Contributes to the Amplification of Th2 Responses to Schistosoma mansoni Glycoconjugates in Mice

Faveeuw, C., Angeli, V., Fontaine, J., Maliszewski, C. R., Capron, A., Kaer, L. V., Moser, M., Capron, M., & Trottein, F. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.169.2.906 · Cited by 87 · see citing works

Review series on helminths, immune modulation and the hygiene hypothesis: Mechanisms underlying helminth modulation of dendritic cell function

Carvalho, L., Sun, J., Kane, C., Marshall, F., Krawczyk, C., & Pearce, E. J. (2009) · Immunology · doi:10.1111/j.1365-2567.2008.03008.x · Cited by 85 · see citing works

IPSE/alpha‐1, a major secretory glycoprotein antigen from schistosome eggs, expresses the Lewis X motif on core‐difucosylated N‐glycans

Wuhrer, M., Balog, C. I. A., Catalina, M., Jones, F. M., Schramm, G., Haas, H., Doenhoff, M., Dunne, D. W., Deelder, A., & Hokke, C. (2006) · The FEBS Journal · doi:10.1111/j.1742-4658.2006.05242.x · Cited by 92 · see citing works

Glycoconjugates in Host-Helminth Interactions

Prasanphanich, N., Mickum, M. L., Heimburg-Molinaro, J., & Cummings, R. (2013) · Frontiers in Immunology · doi:10.3389/fimmu.2013.00240 · Cited by 85 · see citing works

Chronic schistosome infection leads to modulation of granuloma formation and systemic immune suppression

Lundy, S. K., & Lukacs, N. W. (2013) · Frontiers in Immunology · doi:10.3389/fimmu.2013.00039 · Cited by 81 · see citing works

Allergen-specific pattern recognition receptor pathways

Wills-Karp, M. A. (2010) · Current Opinion in Immunology · doi:10.1016/j.coi.2010.10.011 · Cited by 79 · see citing works

Schistosome larvae stimulate macrophage cytokine production through TLR4-dependent and -independent pathways

Jenkins, S., Hewitson, J. P., Ferret-Bernard, S., & Mountford, A. (2005) · International Immunology · doi:10.1093/intimm/dxh319 · Cited by 91 · see citing works

Reprogramming macrophages to an anti‐inflammatory phenotype by helminth antigens reduces murine atherosclerosis

Wolfs, I. M. J., Stöger, J. L., Goossens, P., Pöttgens, C. C. H., Gijbels, M. J., Wijnands, E., van der Vorst, E. P. C., van Gorp, P. J., Beckers, L., Engel, D. A., et al. (2013) · The FASEB Journal · doi:10.1096/fj.13-235911 · Cited by 78 · see citing works

Glycans modulate immune responses in helminth infections and allergy.

van Die, I., & Cummings, R. (2006) · Chemical Immunology · doi:10.1159/000088883 · Cited by 84 · see citing works

Schistosome glycans and innate immunity

Hokke, C., & Yazdanbakhsh, M. (2005) · Parasite immunology (Print) · doi:10.1111/j.1365-3024.2005.00781.x · Cited by 85 · see citing works

A Helminth Glycan Induces APC Maturation via Alternative NF-κB Activation Independent of IκBα Degradation

Thomas, P. G., Carter, M. R., Da’dara, A. A., DeSimone, T. M., & Harn, D. A. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.175.4.2082 · Cited by 76 · see citing works

Chronic helminth infections modulate allergen‐specific immune responses: Protection against development of allergic disorders?

Smits, H. H., & Yazdanbakhsh, M. (2007) · Annals of Medicine · doi:10.1080/07853890701436765 · Cited by 75 · see citing works

Glycans from Fasciola hepatica Modulate the Host Immune Response and TLR-Induced Maturation of Dendritic Cells

Rodríguez, E., Noya, V., Cervi, L., Chiribao, M. L., Brossard, N., Chiale, C., Carmona, C., Giacomini, C., & Freire, T. (2015) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0004234 · Cited by 69 · see citing works

O-Methylated glycans from Toxocara are specific targets for antibody binding in human and animal infections

Schabussová, I., Amer, H., van Die, I., Kosma, P., & Maizels, R. M. (2006) · International Journal for Parasitology · doi:10.1016/j.ijpara.2006.09.006 · Cited by 65 · see citing works

Schistosome immunomodulators

Acharya, S., Da’dara, A. A., & Skelly, P. J. (2021) · PLoS Pathogens · doi:10.1371/journal.ppat.1010064 · Cited by 64 · see citing works

Persistence of Entamoeba histolytica infection in CBA mice owes to intestinal IL-4 production and inhibition of protective IFN-γ

Guo, X., Stroup, S. E., & Houpt, E. R. (2008) · Mucosal Immunology · doi:10.1038/mi.2007.18 · Cited by 64 · see citing works

Mapping fucosylated epitopes on glycoproteins and glycolipids ofSchistosoma mansonicercariae, adult worms and eggs

Robijn, M. L. M., Wuhrer, M., Kornelis, D., Deelder, A. M., Geyer, R., & Hokke, C. H. (2004) · Parasitology · doi:10.1017/s0031182004006390 · Cited by 64 · see citing works

Modulation of Specific and Allergy‐Related Immune Responses by Helminths

Daniłowicz-Luebert, E., O’Regan, N. L., Steinfelder, S., & Hartmann, S. (2011) · BioMed Research International · doi:10.1155/2011/821578 · Cited by 62 · see citing works

Interplay of parasite-driven immune responses and autoimmunity

Zaccone, P., Burton, O. T., & Cooke, A. (2007) · Trends in Parasitology · doi:10.1016/j.pt.2007.10.006 · Cited by 60 · see citing works

Vaccination-induced protection of lambs against the parasitic nematode Haemonchus contortus correlates with high IgG antibody responses to the LDNF glycan antigen

Vervelde, L., Bakker, N., Kooyman, F. N. J., Cornelissen, A. W. C. A., Bank, C. M. C., Nyame, A. K., Cummings, R. D., & van Die, I. (2003) · Glycobiology · doi:10.1093/glycob/cwg107 · Cited by 60 · see citing works

Regulation of Dendritic Cell Function by Pathogen-Derived Molecules Plays a Key Role in Dictating the Outcome of the Adaptive Immune Response

Pearce, E. J., Kane, C. M., & Sun, J. (2005) · KARGER eBooks · doi:10.1159/000088882 · Cited by 60 · see citing works

Helminth‐excreted/secreted products are recognized by multiple receptors on DCs to block the TLR response and bias Th2 polarization in a cRAF dependent pathway

Terrazas, C. A., Alcántara‐Hernández, M., Bonifaz, L. C., Terrazas, L. I., & Satoskar, A. R. (2013) · The FASEB Journal · doi:10.1096/fj.13-228932 · Cited by 58 · see citing works

Worms and the Treatment of Inflammatory Bowel Disease: Are Molecules the Answer?

Ruyssers, N. E., Winter, B. Y. D., Man, J. G. D., Loukas, A. C., Herman, A. G., Pelckmans, P. A., & Moreels, T. G. (2008) · Clinical and Developmental Immunology · doi:10.1155/2008/567314 · Cited by 57 · see citing works

Gender-specific expression of complex-type N-glycans in schistosomes.

Wuhrer, M., Koeleman, C., Fitzpatrick, J. M., Hoffmann, K., Deelder, A., & Hokke, C. (2006) · Glycobiology · doi:10.1093/glycob/cwl020 · Cited by 65 · see citing works

Dendritic cell activation and function in response to Schistosoma mansoni

Perona‐Wright, G., Jenkins, S. J., & MacDonald, A. S. (2006) · International Journal for Parasitology · doi:10.1016/j.ijpara.2006.02.003 · Cited by 56 · see citing works

Molecular basis of worm‐induced immunomodulation

Harnett, W., & Harnett, M. (2006) · Parasite Immunology · doi:10.1111/j.1365-3024.2006.00893.x · Cited by 55 · see citing works

A systemic granulomatous response toSchistosoma mansonieggs alters responsiveness of bone marrow-derived macrophages to Toll-like receptor agonists

Joshi, A., Raymond, T., Coelho, A. L., Kunkel, S. L., & Hogaboam, C. M. (2007) · Journal of Leukocyte Biology · doi:10.1189/jlb.1007689 · Cited by 55 · see citing works

Structural Characterization of Glycans on Omega-1, a Major Schistosoma mansoni Egg Glycoprotein That Drives Th2 Responses

Meevissen, M. H. J., Wuhrer, M., Doenhoff, M. J., Schramm, G., Haas, H., Deelder, A. M., & Hokke, C. H. (2010) · Journal of Proteome Research · doi:10.1021/pr100081c · Cited by 54 · see citing works

TLRs, Treg, and B Cells, an Interplay of Regulation during Helminth Infection

Ludwig‐Portugall, I., & Layland, L. E. (2012) · Frontiers in Immunology · doi:10.3389/fimmu.2012.00008 · Cited by 53 · see citing works

Prevention of psoriasis‐like lesions development in fsn/fsn mice by helminth glycans

Atochina, O., & Harn, D. A. (2006) · Experimental Dermatology · doi:10.1111/j.1600-0625.2006.00431.x · Cited by 53 · see citing works

Complexity and function of cytokine responses in experimental infection by Echinococcus granulosus

Baz, A., Mourglia‐Ettlin, G., & Dematteis, S. (2006) · Immunobiology · doi:10.1016/j.imbio.2005.09.001 · Cited by 51 · see citing works

The schistosome in the mammalian host: understanding the mechanisms of adaptation

Kusel, J. R., Al-Adhami, B. H., & Doenhoff, M. J. (2007) · Parasitology · doi:10.1017/s0031182007002971 · Cited by 50 · see citing works

LacdiNAc- and LacNAc-containing glycans induce granulomas in an in vivo model for schistosome egg-induced hepatic granuloma formation.

van de Vijver, K. K., Deelder, A., Jacobs, W., Marck, E. V., & Hokke, C. (2006) · Glycobiology · doi:10.1093/glycob/cwj058 · Cited by 61 · see citing works

Schistosoma mansoni infection reduces the incidence of murine cerebral malaria

Waknine-Grinberg, J. H., Gold, D., Ohayon, A., Flescher, E., Heyfets, A., Doenhoff, M. J., Schramm, G., Haas, H., & Golenser, J. (2010) · Malaria Journal · doi:10.1186/1475-2875-9-5 · Cited by 49 · see citing works

Specific glycan elements determine differential binding of individual egg glycoproteins of the human parasite Schistosoma mansoni by host C-type lectin receptors

Meevissen, M. H. J., Driessen, N. N., Smits, H. H., Versteegh, R., van Vliet, S. J., van Kooyk, Y., Schramm, G., Deelder, A. M., Haas, H., Yazdanbakhsh, M., et al. (2012) · International Journal for Parasitology · doi:10.1016/j.ijpara.2012.01.004 · Cited by 48 · see citing works

Dominant antibody responses to Fucα1-3GalNAc and Fucα1-2Fucα1-3GlcNAc containing carbohydrate epitopes in Pan troglodytes vaccinated and infected with Schistosoma mansoni

van Remoortere, A., Vermeer, H. J., van Roon, A. M., Langermans, J. A. M., Thomas, A., Wilson, R. A., van Die, I., EIJNDEN, D. H. V. D., Ágoston, K., Kerékgyártó, J., et al. (2003) · Experimental Parasitology · doi:10.1016/j.exppara.2003.12.005

Schistosoma mansoni egg glycoproteins and C-type lectins of host immune cells: molecular partners that shape immune responses.

Meevissen, M. H. J., Yazdanbakhsh, M., & Hokke, C. (2012) · Experimental parasitology · doi:10.1016/j.exppara.2011.05.005 · Cited by 56 · see citing works

Natural glycans and glycoconjugates as immunomodulating agents.

Chlubnová, I., Sylla, B., Nugier-Chauvin, C., Daniellou, R., Legentil, L., Králová, B., & Ferrières, V. (2011) · Natural product reports (Print) · doi:10.1039/c1np00005e · Cited by 43 · see citing works

Alzheimer's disease vaccine development: A new strategy focusing on immune modulation

Marciani, D. J. (2015) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2015.08.008 · Cited by 46 · see citing works

Neutral oligosaccharides in colostrum in relation to maternal allergy and allergy development in children up to 18 months of age

Sjögren, Y. M., Duchén, K., Lindh, F., Björkstén, B., & Sverremark‐Ekström, E. (2006) · Pediatric Allergy and Immunology · doi:10.1111/j.1399-3038.2006.00486.x · Cited by 46 · see citing works

Schistosoma japonicum infection modulates the development of allergen-induced airway inflammation in mice

Mo, H.-M., Lei, J., Jiang, Z., Wang, C.-Z., Cheng, Y., Li, Y., & Liu, W. (2008) · Parasitology Research · doi:10.1007/s00436-008-1114-1 · Cited by 45 · see citing works

Fasciola hepatica Surface Coat Glycoproteins Contain Mannosylated and Phosphorylated N-glycans and Exhibit Immune Modulatory Properties Independent of the Mannose Receptor

Ravidà, A., Aldridge, A. M., Driessen, N. N., Heus, F. A. H., Hokke, C. H., & O’Neill, S. M. (2016) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0004601 · Cited by 45 · see citing works

Schistosoma mansoni-infected mice produce antibodies that cross-react with plant, insect, and mammalian glycoproteins and recognize the truncated biantennaryN-glycan Man3GlcNAc2-R

van Remoortere, A. (2003) · Glycobiology · doi:10.1093/glycob/cwg025 · Cited by 43 · see citing works

Carbohydrate components of Taenia crassiceps metacestodes display Th2-adjuvant and anti-inflammatory properties when co-injected with bystander antigen

Gómez-García, L., Rivera-Montoya, I., Rodríguez‐Sosa, M., & Terrazas, L. I. (2006) · Parasitology Research · doi:10.1007/s00436-006-0159-2 · Cited by 42 · see citing works

Physiological effects, biosynthesis, and derivatization of key human milk tetrasaccharides, lacto-N-tetraose, and lacto-N-neotetraose

Zhu, Y., Luo, G., Wan, L., Meng, J., Lee, S. Y., & Mu, W. (2021) · Critical Reviews in Biotechnology · doi:10.1080/07388551.2021.1944973 · Cited by 42 · see citing works

Induction of Th2 Responses and IgE Is Largely Due to Carbohydrates Functioning as Adjuvants on <i>Schistosoma mansoni</i> Egg Antigens

Okano, M., Satoskar, A. R., Nishizaki, K., Abe, M., & Harn, D. A. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.163.12.6712 · Cited by 206 · see citing works

Lewisx-containing oligosaccharide attenuates schistosome egg antigen-induced immune depression in human schistosomiasis

Velupillai, P., Reis, E. A., dos Reis, M. G., & Harn, D. A. (2000) · Human Immunology · doi:10.1016/s0198-8859(99)00136-6 · Cited by 72 · see citing works

Schistosome N‐glycans containing core α3‐fucose and core β2‐xylose epitopes are strong inducers of Th2 responses in mice

Faveeuw, C., Mallevaey, T., Paschinger, K., Wilson, I. B. H., Fontaine, J., Mollicone, R., Oriol, R., Altmann, F., Lerouge, P., Capron, M., et al. (2003) · European Journal of Immunology · doi:10.1002/eji.200323717 · Cited by 117 · see citing works

Lacto-N-fucopentaose III (Lewis x), a target of the antibody response in mice vaccinated with irradiated cercariae of Schistosoma mansoni

Richter, D., Incani, R. N., & Harn, D. A. (1996) · Infection and Immunity · doi:10.1128/iai.64.5.1826-1831.1996 · Cited by 39 · see citing works

Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses

Everts, B., Perona‐Wright, G., Smits, H. H., Hokke, C. H., van der Ham, A. J., Fitzsimmons, C. M., Doenhoff, M. J., van der Bosch, J., Mohrs, K., Haas, H., et al. (2009) · The Journal of Experimental Medicine · doi:10.1084/jem.20082460 · Cited by 330 · see citing works