Review series on helminths, immune modulation and the hygiene hypothesis: Mechanisms underlying helminth modulation of dendritic cell function

Recognition of microorganisms and activation of the immune response

Medzhitov, R. (2007) · Nature · doi:10.1038/nature06246 · Cited by 2,862 · see citing works

TLR signaling pathways

Takeda, K., & Akira, S. (2004) · Seminars in Immunology · doi:10.1016/j.smim.2003.10.003 · Cited by 2,461 · see citing works

Dendritic Cells

Mellman, I., & Steinman, R. M. (2001) · Cell · doi:10.1016/s0092-8674(01)00449-4 · Cited by 2,256 · see citing works

Fibrotic disease and the TH1/TH2 paradigm

Wynn, T. A. (2004) · Nature Reviews Immunology · doi:10.1038/nri1412 · Cited by 1,765 · see citing works

Helminth infections: the great neglected tropical diseases

Hotez, P. J., Brindley, P. J., Bethony, J. M., King, C. H., Pearce, E. J., & Jacobson, J. (2008) · Journal of Clinical Investigation · doi:10.1172/jci34261 · Cited by 1,572 · see citing works

TLR signaling

Kawai, T., & Akira, S. (2007) · Seminars in Immunology · doi:10.1016/j.smim.2006.12.004 · Cited by 1,404 · see citing works

Lipopolysaccharide-enhanced, Toll-like Receptor 4–dependent T Helper Cell Type 2 Responses to Inhaled Antigen

Eisenbarth, S. C., Piggott, D. A., Huleatt, J. W., Visintin, I., Herrick, C. A., & Bottomly, K. (2002) · The Journal of Experimental Medicine · doi:10.1084/jem.20021340 · Cited by 1,171 · see citing works

Mycobacteria Target DC-SIGN to Suppress Dendritic Cell Function

Geijtenbeek, T. B. H., van Vliet, S. J., Koppel, E. A., Sánchez‐Hernández, M., Vandenbroucke‐Grauls, C. M. J. E., Appelmelk, B. J., & van Kooyk, Y. (2002) · The Journal of Experimental Medicine · doi:10.1084/jem.20021229 · Cited by 1,058 · see citing works

Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells

Amsen, D., Blander, J. M., Lee, G. R., Tanigaki, K., Honjo, T., & Flavell, R. A. (2004) · Cell · doi:10.1016/s0092-8674(04)00451-9 · Cited by 902 · see citing works

Cutting Edge: Different Toll-Like Receptor Agonists Instruct Dendritic Cells to Induce Distinct Th Responses via Differential Modulation of Extracellular Signal-Regulated Kinase-Mitogen-Activated Protein Kinase and c-Fos

Agrawal, S., Agrawal, A., Doughty, B. L., Gerwitz, A., Blenis, J., Dyke, T. E. V., & Pulendran, B. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.171.10.4984 · Cited by 726 · see citing works

Suppression of allergic airway inflammation by helminth-induced regulatory T cells

Wilson, M. S., Taylor, M. D., Balic, A., Finney, C. A. M., Lamb, J. R., & Maizels, R. M. (2005) · The Journal of Experimental Medicine · doi:10.1084/jem.20042572 · Cited by 611 · see citing works

C-Type Lectin DC-SIGN Modulates Toll-like Receptor Signaling via Raf-1 Kinase-Dependent Acetylation of Transcription Factor NF-κB

Gringhuis, S. I., den Dunnen, J., Litjens, M., Hof, B. V. H., van Kooyk, Y., & Geijtenbeek, T. B. H. (2007) · Immunity · doi:10.1016/j.immuni.2007.03.012 · Cited by 588 · see citing works

A Novel Host-Parasite Lipid Cross-talk

van der Kleij, D., Latz, E., Brouwers, J. F. H. M., Kruize, Y. C. M., Schmitz, M., Kurt-Jones, E. A., Espevik, T., de Jong, E. C., Kapsenberg, M. L., Golenbock, D. T., et al. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m206941200 · Cited by 587 · see citing works

Interleukin‐4‐ and interleukin‐13‐mediated host protection against intestinal nematode parasites

Finkelman, F. D., Shea‐Donohue, T., Morris, S. C., Gildea, L. A., Strait, R. T., Madden, K. B., Schopf, L. R., & Urban, J. F. (2004) · Immunological Reviews · doi:10.1111/j.0105-2896.2004.00192.x · Cited by 515 · see citing works

Epithelial-cell-intrinsic IKK-β expression regulates intestinal immune homeostasis

Zaph, C., Troy, A. E., Taylor, B. C., Berman-Booty, L. D., Guild, K. J., Du, Y., Yost, E. A., Gruber, A. D., May, M. J., Greten, F. R., et al. (2007) · Nature · doi:10.1038/nature05590 · Cited by 496 · see citing works

A Toll-Like Receptor 2 Ligand Stimulates Th2 Responses In Vivo, via Induction of Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase and c-Fos in Dendritic Cells

Dillon, S. M., Agrawal, A., Dyke, T. E. V., Landreth, G. E., McCauley, L. K., Koh, A. J., Maliszewski, C. R., Akira, S., & Pulendran, B. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.8.4733 · Cited by 460 · see citing works

How C-type lectins detect pathogens

Cambi, A., Koopman, M., & Figdor, C. G. (2005) · Cellular Microbiology · doi:10.1111/j.1462-5822.2005.00506.x · Cited by 455 · see citing works

The nervous system and innate immunity: the neuropeptide connection

Brogden, K. A., Guthmiller, J. M., Salzet, M., & ZASLOFF, M. A. (2005) · Nature Immunology · doi:10.1038/ni1209 · Cited by 445 · see citing works

Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways

Hoebe, K. H. N., Janssen, E. M., Kim, S. O., Alexopoulou, L., Flavell, R. A., Han, J., & Beutler, B. (2003) · Nature Immunology · doi:10.1038/ni1010 · Cited by 444 · see citing works

Cutting Edge: Carbohydrate Profiling Identifies New Pathogens That Interact with Dendritic Cell-Specific ICAM-3-Grabbing Nonintegrin on Dendritic Cells

Appelmelk, B. J., van Die, I., van Vliet, S. J., Vandenbroucke‐Grauls, C. M. J. E., Geijtenbeek, T. B. H., & van Kooyk, Y. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.170.4.1635 · Cited by 431 · see citing works

Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch

Amsen, D., Antov, A., Jankovic, D., Sher, A., Radtke, F., Souabni, A., Busslinger, M., McCright, B., Gridley, T., & Flavell, R. A. (2007) · Immunity · doi:10.1016/j.immuni.2007.05.021 · Cited by 396 · see citing works

Notch Directly Regulates Gata3 Expression during T Helper 2 Cell Differentiation

Fang, T., Yashiro–Ohtani, Y., Bianco, C. D., Knoblock, D. M., Blacklow, S. C., & Pear, W. S. (2007) · Immunity · doi:10.1016/j.immuni.2007.04.018 · Cited by 364 · see citing works

Control of adaptive immune responses by Toll-like receptors

Barton, G. M., & Medzhitov, R. M. (2002) · Current Opinion in Immunology · doi:10.1016/s0952-7915(02)00343-6 · Cited by 325 · see citing works

Schistosoma mansoni antigens modulate the activity of the innate immune response and prevent onset of type 1 diabetes

Zaccone, P., Fehervari, Z. T., Jones, F. M., Sidobre, S., Kronenberg, M., Dunne, D. W., & Cooke, A. (2003) · European Journal of Immunology · doi:10.1002/eji.200323910 · Cited by 317 · see citing works

The dendritic cell-specific C-type lectin DC-SIGN is a receptor for Schistosoma mansoni egg antigens and recognizes the glycan antigen Lewis x

van Die, I. (2003) · Glycobiology · doi:10.1093/glycob/cwg052 · Cited by 316 · see citing works

Unique gene expression profiles of human macrophages and dendritic cells to phylogenetically distinct parasites

Chaussabel, D., Semnani, R. T., McDowell, M. A., Sacks, D. L., Sher, A., & Nutman, T. B. (2003) · Blood · doi:10.1182/blood-2002-10-3232 · Cited by 315 · see citing works

Maturation of Dendritic Cell 2 Phenotype by a Helminth Glycan Uses a Toll-Like Receptor 4-Dependent Mechanism

Thomas, P. G., Carter, M. R., Atochina, O., Da’dara, A. A., Piskorska, D., McGuire, E., & Harn, D. A. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.171.11.5837 · Cited by 300 · see citing works

Delta1-Notch3 Interactions Bias the Functional Differentiation of Activated CD4+ T Cells

Maekawa, Y., Tsukumo, S., Chiba, S., Hirai, H., Hayashi, Y., Okada, H., Kishihara, K., & Yasutomo, K. (2003) · Immunity · doi:10.1016/s1074-7613(03)00270-x · Cited by 289 · see citing works

Notch signaling is an important regulator of type 2 immunity

Tu, L., Fang, T., Artis, D., Shestova, O. E., Pross, S. E., Maillard, I. P., & Pear, W. S. (2005) · The Journal of Experimental Medicine · doi:10.1084/jem.20050923 · Cited by 283 · see citing works

Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21.

Minter, L. M., Turley, D. M., Das, P., Shin, H. M., Joshi, I., Lawlor, R. G., Cho, O. H., Palaga, T., Gottipati, S., Telfer, J. C., et al. (2005) · PubMed · Cited by 281 · see citing works

CD8− Dendritic Cell Activation Status Plays an Integral Role in Influencing Th2 Response Development

MacDonald, A. S., Straw, A. D., Bauman, B. E., & Pearce, E. J. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.167.4.1982 · Cited by 280 · see citing works

IL-23 and IL-17 in tuberculosis

Khader, S. A., & Cooper, A. M. (2008) · Cytokine · doi:10.1016/j.cyto.2007.11.022 · Cited by 277 · see citing works

The Major Glycoprotein Allergen from Arachis hypogaea, Ara h 1, Is a Ligand of Dendritic Cell-Specific ICAM-Grabbing Nonintegrin and Acts as a Th2 Adjuvant In Vitro

Shreffler, W. G., Castro, R., Kucuk, Z. Y., Charlop–Powers, Z., Grishina, G. T., Yoo, S., Burks, A. W., & Sampson, H. A. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.6.3677 · Cited by 268 · see citing works

Schistosoma mansoni soluble egg antigens are internalized by human dendritic cells through multiple C-type lectins and suppress TLR-induced dendritic cell activation

van Liempt, E., van Vliet, S. J., Engering, A. J., García-Vallejo, J. J., Bank, C. M. C., Sánchez‐Hernández, M., van Kooyk, Y., & van Die, I. (2007) · Molecular Immunology · doi:10.1016/j.molimm.2006.12.012 · Cited by 255 · see citing works

In the Absence of IL-12, CD4+ T Cell Responses to Intracellular Pathogens Fail to Default to a Th2 Pattern and Are Host Protective in an IL-10−/− Setting

Jankovic, D. L., Kullberg, M. C., Hieny, S. E., Caspar, P., Collazo, C. M., & Sher, A. (2002) · Immunity · doi:10.1016/s1074-7613(02)00278-9 · Cited by 252 · see citing works

Single Cell Analysis Reveals That IL-4 Receptor/Stat6 Signaling Is Not Required for the In Vivo or In Vitro Development of CD4+ Lymphocytes with a Th2 Cytokine Profile

Jankovic, D. L., Kullberg, M. C., Noben-Trauth, N., Caspar, P., Paul, W. E., & Sher, A. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.164.6.3047 · Cited by 243 · see citing works

Immunomodulation via Novel Use of TLR4 by the Filarial Nematode Phosphorylcholine-Containing Secreted Product, ES-62

Goodridge, H. S., Marshall, F. A., Else, K. J., Houston, K. M., EGAN, C. A., Al‐Riyami, L., Liew, F.-Y., Harnett, W., & Harnett, M. M. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.174.1.284 · Cited by 239 · see citing works

Helminth Antigens Modulate TLR-Initiated Dendritic Cell Activation

Kane, C. M., Cervi, L., Sun, J., McKee, A. S., Masek, K. S., Shapira, S. D., Hunter, C. A., & Pearce, E. J. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.12.7454 · Cited by 229 · see citing works

Lacto- <i>N</i> -fucopentaose III Found on <i>Schitosoma mansoni</i> Egg Antigens Functions as Adjuvant for Proteins by Inducing Th2-Type Response

Okano, M., Satoskar, A. R., Nishizaki, K., & Harn, D. A. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.167.1.442 · Cited by 210 · see citing works

Induction of Th2 Responses and IgE Is Largely Due to Carbohydrates Functioning as Adjuvants on <i>Schistosoma mansoni</i> Egg Antigens

Okano, M., Satoskar, A. R., Nishizaki, K., Abe, M., & Harn, D. A. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.163.12.6712 · Cited by 206 · see citing works

The Neglected Tropical Diseases: The Ancient Afflictions of Stigma and Poverty and the Prospects for their Control and Elimination

Hotez, P. J., Ottesen, E. A., Fenwick, A., & Molyneux, D. H. (2006) · Springer eBooks · doi:10.1007/0-387-33026-7_3 · Cited by 200 · see citing works

Cutting Edge: Th2 Response Induction by Dendritic Cells: A Role for CD40

MacDonald, A. S., Straw, A. D., Dalton, N. M., et al. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.168.2.537 · Cited by 197 · see citing works

Impairment of dendritic cell function by excretory‐secretory products: A potential mechanism for nematode‐induced immunosuppression

Segura, M., Su, Z., Piccirillo, C. A., & Stevenson, M. M. (2007) · European Journal of Immunology · doi:10.1002/eji.200636553 · Cited by 196 · see citing works

Parasitic worms and inflammatory diseases

Zaccone, P., Fehervari, Z. T., Phillips, J. M., Dunne, D. W., & Cooke, A. (2006) · Parasite Immunology · doi:10.1111/j.1365-3024.2006.00879.x · Cited by 187 · see citing works

Dendritic cells and C‐type lectin receptors: coupling innate to adaptive immune responses

van Vliet, S. J., García-Vallejo, J. J., & van Kooyk, Y. (2008) · Immunology and Cell Biology · doi:10.1038/icb.2008.55 · Cited by 182 · see citing works

Selective maturation of dendritic cells by Nippostrongylus brasiliensis‐secreted proteins drives Th2 immune responses

Balic, A., Harcus, Y. M., Holland, M., & Maizels, R. (2004) · European Journal of Immunology · doi:10.1002/eji.200425167 · Cited by 180 · see citing works

Cutting Edge: Dendritic Cells Copulsed with Microbial and Helminth Antigens Undergo Modified Maturation, Segregate the Antigens to Distinct Intracellular Compartments, and Concurrently Induce Microbe-Specific Th1 and Helminth-Specific Th2 Responses

Cervi, L., MacDonald, A. S., Kane, C. M., Dzierszinski, F. S., & Pearce, E. J. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.4.2016 · Cited by 171 · see citing works

Double-stranded RNAs from the Helminth Parasite Schistosoma Activate TLR3 in Dendritic Cells

Aksoy, E., Zouain, C. S., Vanhoutte, F., Fontaine, J., Pavelka, N., Thiéblemont, N., Willems, F., Ricciardi‐Castagnoli, P., Goldman, M., Capron, M., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m411223200 · Cited by 166 · see citing works

Echinococcus granulosus Antigen B Impairs Human Dendritic Cell Differentiation and Polarizes Immature Dendritic Cell Maturation towards a Th2 Cell Response

Riganò, R., Buttari, B., Profumo, E., Ortona, E., Delunardo, F., Margutti, P., Mattei, V., Teggi, A., Sorice, M., & Siracusano, A. (2007) · Infection and Immunity · doi:10.1128/iai.01156-06 · Cited by 159 · see citing works

Protective effect of Schistosoma mansoni infection on allergic airway inflammation depends on the intensity and chronicity of infection

Smits, H. H., Hammad, H., van Nimwegen, M., et al. (2007) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2007.06.009 · Cited by 158 · see citing works

Dendritic Cell Expression of OX40 Ligand Acts as a Costimulatory, Not Polarizing, Signal for Optimal Th2 Priming and Memory Induction In Vivo

Jenkins, S. J., Perona‐Wright, G., Worsley, A. G. F., et al. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.179.6.3515 · Cited by 140 · see citing works

Immune biasing by helminth glycans

Thomas, P. G., & Harn, D. A. (2003) · Cellular Microbiology · doi:10.1046/j.1462-5822.2003.00337.x · Cited by 137 · see citing works

Novel Effector Molecules in Type 2 Inflammation: Lessons Drawn from Helminth Infection and Allergy

Nair, M. G., Guild, K. J., & Artis, D. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.3.1393 · Cited by 130 · see citing works

Both Free-Living and Parasitic Nematodes Induce a Characteristic Th2 Response That Is Dependent on the Presence of Intact Glycans

Tawill, S. A., Goff, L. L., Ali, F., Blaxter, M., & Allen, J. E. (2003) · Infection and Immunity · doi:10.1128/iai.72.1.398-407.2004 · Cited by 126 · see citing works

Schistosome N‐glycans containing core α3‐fucose and core β2‐xylose epitopes are strong inducers of Th2 responses in mice

Faveeuw, C., Mallevaey, T., Paschinger, K., Wilson, I. B. H., Fontaine, J., Mollicone, R., Oriol, R., Altmann, F., Lerouge, P., Capron, M., et al. (2003) · European Journal of Immunology · doi:10.1002/eji.200323717 · Cited by 117 · see citing works

Impaired T Helper 2 Response to Aeroallergen in Helminth‐Infected Patients with Asthma

Araujo, M. I. A. S., Hoppe, B. S., Medeiros, M., et al. (2004) · The Journal of Infectious Diseases · doi:10.1086/425017 · Cited by 109 · see citing works

DC-SIGN Mediates Binding of Dendritic Cells to Authentic Pseudo-LewisY Glycolipids of Schistosoma mansoni Cercariae, the First Parasite-specific Ligand of DC-SIGN

Meyer, S., van Liempt, E., Imberty, A., van Kooyk, Y., Geyer, H., Geyer, R., & van Die, I. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m507100200 · Cited by 102 · see citing works

Suppression of Th2 Cell Development by Notch Ligands Delta1 and Delta4

Sun, J., Krawczyk, C. J., & Pearce, E. J. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.3.1655 · Cited by 100 · see citing works

Modulation of the allergic reactivity of slum children by helminthic infection

Hagel, I., Lynch, N. R., Pérez, M., et al. (1993) · Parasite Immunology · doi:10.1111/j.1365-3024.1993.tb00615.x · Cited by 95 · see citing works

Parasite-Induced Th2 Polarization Is Associated with Down-Regulated Dendritic Cell Responsiveness to Th1 Stimuli and a Transient Delay in T Lymphocyte Cycling

Jankovic, D. L., Kullberg, M. C., Caspar, P., & Sher, A. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.4.2419 · Cited by 92 · see citing works

Phosphorylcholine mimics the effects of ES-62 on macrophages and dendritic cells

GOODRIDGE, H. S., McGUINESS, S., HOUSTON, K. M., EGAN, C. A., AL‐RIYAMI, L., ALCOCER, M. J. C., HARNETT, M. M., & HARNETT, W. (2007) · Parasite Immunology · doi:10.1111/j.1365-3024.2006.00926.x · Cited by 89 · see citing works

Essential role for TLR4 and MyD88 in the development of chronic intestinal nematode infection

Helmby, H., & Grencis, R. K. (2003) · European Journal of Immunology · doi:10.1002/eji.200324264 · Cited by 88 · see citing works

Cutting Edge: Polarized Th Cell Response Induction by Transferred Antigen-Pulsed Dendritic Cells Is Dependent on IL-4 or IL-12 Production by Recipient Cells

MacDonald, A. S., & Pearce, E. J. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.168.7.3127 · Cited by 80 · see citing works

A Helminth Glycan Induces APC Maturation via Alternative NF-κB Activation Independent of IκBα Degradation

Thomas, P. G., Carter, M. R., Da’dara, A. A., DeSimone, T. M., & Harn, D. A. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.175.4.2082 · Cited by 76 · see citing works

TLR Ligands Can Activate Dendritic Cells to Provide a MyD88-Dependent Negative Signal for Th2 Cell Development

Sun, J., Walsh, M. C., Villarino, A. V., Cervi, L., Hunter, C. A., Choi, Y., & Pearce, E. J. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.174.2.742 · Cited by 74 · see citing works

Th2 Differentiation Is Unaffected by Jagged2 Expression on Dendritic Cells

Krawczyk, C. M., Sun, J., & Pearce, E. J. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.12.7931 · Cited by 71 · see citing works

Adaptation of a nematode parasite to living within the mammalian epithelium

Tilney, L. G., Connelly, P. S., Guild, G. M., Vranich, K. A., & Artis, D. (2005) · Journal of Experimental Zoology Part A Comparative Experimental Biology · doi:10.1002/jez.a.214 · Cited by 70 · see citing works

Dendritic cell expression of the Notch ligand jagged2 is not essential for Th2 response induction in vivo

Worsley, A. G. F., LeibundGut‐Landmann, S., Slack, E. M. C., et al. (2008) · European Journal of Immunology · doi:10.1002/eji.200737335 · Cited by 63 · see citing works

Dendritic Cell-Intrinsic Expression of NF-κB1 Is Required to Promote Optimal Th2 Cell Differentiation

Artis, D., Kane, C. M., Fiore, J., Zaph, C., Shapira, S. D., Joyce, K. L., MacDonald, A. S., Hunter, C. A., Scott, P., & Pearce, E. J. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.174.11.7154 · Cited by 58 · see citing works

Regulatory T Cells Induced by Parasites and the Modulation of Allergic Responses

Wilson, M. S., & Maizels, R. M. (2005) · KARGER eBooks · doi:10.1159/000088892 · Cited by 57 · see citing works

Lack of antigen-specific Th1 response alters granuloma formation and composition inSchistosoma mansoni-infected MyD88-/- mice

Layland, L. E., Wagner, H., & da Costa, C. P. (2005) · European Journal of Immunology · doi:10.1002/eji.200526273 · Cited by 54 · see citing works

Toll-like receptor (TLR)2 and TLR3 sensing is required for dendritic cell activation, but dispensable to control Schistosoma mansoni infection and pathology

Vanhoutte, F., Breuilh, L., Fontaine, J., et al. (2007) · Microbes and Infection · doi:10.1016/j.micinf.2007.09.013 · Cited by 43 · see citing works

Carbohydrate components of Taenia crassiceps metacestodes display Th2-adjuvant and anti-inflammatory properties when co-injected with bystander antigen

Gómez-García, L., Rivera-Montoya, I., Rodríguez‐Sosa, M., & Terrazas, L. I. (2006) · Parasitology Research · doi:10.1007/s00436-006-0159-2 · Cited by 42 · see citing works

Toll-like receptor 4 (TLR4) is required for protective immunity to larval Strongyloides stercoralis in mice

Kerepesi, L. A., Hess, J. A., Leon, O., et al. (2006) · Microbes and Infection · doi:10.1016/j.micinf.2006.10.003 · Cited by 37 · see citing works

Induction of Enhanced Immunity to Intestinal Nematodes Using IL-9-Producing Dendritic Cells

Leech, M. D., & Grencis, R. K. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.176.4.2505 · Cited by 36 · see citing works

Proteomic profiling reveals that Th2‐inducing dendritic cells stimulated with helminth antigens have a ‘limited maturation’ phenotype

Ferret‐Bernard, S., Curwen, R. S., & Mountford, A. P. (2008) · PROTEOMICS · doi:10.1002/pmic.200700538 · Cited by 27 · see citing works

Full Development of Th2 Immunity Requires Both Innate and Adaptive Sources of CD154

Jenkins, S. J., Perona‐Wright, G., & MacDonald, A. S. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.12.8083 · Cited by 24 · see citing works

Specifying Helper T Cell Fates During Immunity

Chang, J. T., & Reiner, S. L. (2008) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/01.mpg.0000313832.47207.0e · Cited by 5 · see citing works

Epstein-Barr virus-dependent lymphoproliferative disease: critical role of IL-6

(2000) · Pure Amsterdam UMC · doi:10.1002/1521-4141(200007)30:7 · Cited by 1 · see citing works

Helminth cysteine proteases inhibit TRIF-dependent activation of macrophages via degradation of TLR3

Donnelly, S., O’Neill, S. M., Stack, C. M., Robinson, M. W., Turnbull, L., Whitchurch, C., & Dalton, J. P. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.060368 · Cited by 140 · see citing works

Cytokines and immunoglobulin g response in donkeys with spontaneous Setaria equine infection

El Namaky, A. H., Hendawy, S. H., Abo-Aziza, F. A., & Ashry, H. M. (2019) · BULGARIAN JOURNAL OF VETERINARY MEDICINE · doi:10.15547/bjvm.2049 · Cited by 4 · see citing works

Emergent and Neglected Equine Filariosis in Egypt: Species Diversity and Host Immune Response

Abo-Aziza, F. A. M., Hendawy, S. H. M., Abdullah, H. H. A. M., El Namaky, A., Laidoudi, Y., & Mediannikov, O. (2022) · Pathogens · doi:10.3390/pathogens11090979 · Cited by 4 · see citing works

Crucial Roles of Effectors in Interactions between Horticultural Crops and Pathogens

Liu, T., Chen, Y., Tian, S., et al. (2023) · Horticulturae · doi:10.3390/horticulturae9020250 · Cited by 9 · see citing works

20 Effector proteins of bacterial type III protein secretion systems: Elucidating their biochemical effects on eukaryotic signaling cascades

Orth, K., Dixon, J. E., & Bliska, J. B. (2002) · Methods in microbiology · doi:10.1016/s0580-9517(02)31021-3

Prediction of effector proteins and their implications in pathogenicity of phytopathogenic filamentous fungi: A review

Wu, Y., Xie, L., Jiang, Y., & Li, T. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.02.133 · Cited by 35 · see citing works

Remote homology clustering identifies lowly conserved families of effector proteins in plant-pathogenic fungi

Jones, D., Moolhuijzen, P., & Hane, J. K. (2021) · Microbial Genomics · doi:10.1099/mgen.0.000637 · Cited by 13 · see citing works

Microbial Pathogen Effectors in Plant Disease

Pelgrom, A. J. E., & den Ackerveken, G. F. J. M. V. (2016) · Encyclopedia of Life Sciences · doi:10.1002/9780470015902.a0023724 · Cited by 7 · see citing works