Cited by 610Maternal Mental Health During Pregnancy and PostpartumAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesMaternal and Neonatal Healthcare

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The Prevalence of Anxiety Disorders During Pregnancy and the Postpartum Period: A Multivariate Bayesian Meta-Analysis

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Fawcett, Emily J., Fairbrother, Nichole, Cox, Megan L., White, Ian R., Fawcett, Jonathan M.·2019·The Journal of Clinical Psychiatry

DOI 10.4088/jcp.18r12527PMC PMC6839961

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Abstract

OBJECTIVE: To estimate the prevalence of anxiety disorders in pregnant and postpartum women and identify predictors accounting for variability across estimates. DATA SOURCES: An electronic search of PsycINFO and PubMed was conducted from inception until July 2016, without date or language restrictions, and supplemented by articles referenced in the obtained sources. A Boolean search phrase utilized a combination of keywords related to pregnancy, postpartum, prevalence, and specific anxiety disorders. STUDY SELECTION: Articles reporting the prevalence of 1 or more of 8 common anxiety disorders in pregnant or postpartum women were included. A total of 2,613 records were retrieved, with 26 studies ultimately included. DATA EXTRACTION: Anxiety disorder prevalence and potential predictor variables (eg, parity) were extracted from each study. A Bayesian multivariate modeling approach estimated the prevalence and between-study heterogeneity of each disorder and the prevalence of having 1 or more anxiety disorder. RESULTS: Individual disorder prevalence estimates ranged from 1.1% for posttraumatic stress disorder to 4.8% for specific phobia, with the prevalence of having at least 1 or more anxiety disorder estimated to be 20.7% (95% highest density interval [16.7% to 25.4%]). Substantial between-study heterogeneity was observed, suggesting that "true" prevalence varies broadly across samples. There was evidence of a small (3.1%) tendency for pregnant women to be more susceptible to anxiety disorders than postpartum women. CONCLUSIONS: Peripartum anxiety disorders are more prevalent than previously thought, with 1 in 5 women in a typical sample meeting diagnostic criteria for at least 1 disorder. These findings highlight the need for anxiety screening, education, and referral in obstetrics and gynecology settings.

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Authors: Fawcett, E. J., Fairbrother, N., Cox, M. L., White, I. R., & Fawcett, J. M.
Affiliations: Memorial University of Newfoundland (CA)
University of British Columbia (CA)
MRC Clinical Trials Unit at UCL (GB)
ORCID: Fawcett, Emily J.
Fairbrother, Nichole
White, Ian R.
Fawcett, Jonathan M.
Venue: The Journal of Clinical Psychiatry
Publisher: Physicians Postgraduate Press, Inc
Published: 2019-07-23
Volume: 80
Issue: 4
ISSN: 0160-6689 (ISSN-L)
1555-2101
DOI: 10.4088/jcp.18r12527
PMC: PMC6839961
OpenAlex: W2964029936
Cited by: 609
References: 119
Citations by year: 2026: 98 · 2025: 124 · 2024: 109 · 2023: 98 · 2022: 86 · 2021: 67 · 2020: 22 · 2019: 3
FWCI: 40.98
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: The Journal of Clinical Psychiatry (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
UCL Discovery (University College London) (submittedVersion)
Funders: Medical Research Council (MC_UU_12023/21)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Maternal and Neonatal Healthcare
Keywords: anxiety disorders, pregnancy, postpartum period, perinatal anxiety, prevalence, post-traumatic stress disorder, specific phobia, parity, study heterogeneity, anxiety screening, obstetrics and gynecology
MeSH terms: Anxiety Disorders, Bayes Theorem, Female, Humans, Pregnancy, Pregnancy Complications, Puerperal Disorders, Prevalence

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The Prevalence of Anxiety Disorders During Pregnancy and the Postpartum Period: A Multivariate Bayesian Meta-Analysis

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