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The Prevalence of Anxiety Disorders During Pregnancy and the Postpartum Period: A Multivariate Bayesian Meta-Analysis
Open accessAbstract
OBJECTIVE: To estimate the prevalence of anxiety disorders in pregnant and postpartum women and identify predictors accounting for variability across estimates. DATA SOURCES: An electronic search of PsycINFO and PubMed was conducted from inception until July 2016, without date or language restrictions, and supplemented by articles referenced in the obtained sources. A Boolean search phrase utilized a combination of keywords related to pregnancy, postpartum, prevalence, and specific anxiety disorders. STUDY SELECTION: Articles reporting the prevalence of 1 or more of 8 common anxiety disorders in pregnant or postpartum women were included. A total of 2,613 records were retrieved, with 26 studies ultimately included. DATA EXTRACTION: Anxiety disorder prevalence and potential predictor variables (eg, parity) were extracted from each study. A Bayesian multivariate modeling approach estimated the prevalence and between-study heterogeneity of each disorder and the prevalence of having 1 or more anxiety disorder. RESULTS: Individual disorder prevalence estimates ranged from 1.1% for posttraumatic stress disorder to 4.8% for specific phobia, with the prevalence of having at least 1 or more anxiety disorder estimated to be 20.7% (95% highest density interval [16.7% to 25.4%]). Substantial between-study heterogeneity was observed, suggesting that "true" prevalence varies broadly across samples. There was evidence of a small (3.1%) tendency for pregnant women to be more susceptible to anxiety disorders than postpartum women. CONCLUSIONS: Peripartum anxiety disorders are more prevalent than previously thought, with 1 in 5 women in a typical sample meeting diagnostic criteria for at least 1 disorder. These findings highlight the need for anxiety screening, education, and referral in obstetrics and gynecology settings.
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“Pregnancy, therefore, poses a significant risk for parental psychopathology, particularly internalizing problems (i.e., depression and anxiety [5, 6, 7]).”
From Trajectories of Maternal and Paternal Internalizing Symptoms from Pregnancy to 2 Years Postpartum: Identifying Modifiable Risk and Protective Factors (2024) · cites this paper as [5]
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“Specifically, one in five pregnant or postpartum women experiences one or more types of anxiety disorders or anxiety-related conditions during this period.”
From Determinants of the choice of delivery mode in pregnant women: a convergent parallel mixed-methods study protocol (2026) · cites this paper as [13]
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Metadata
- Authors
- Fawcett, E. J., Fairbrother, N., Cox, M. L., White, I. R., & Fawcett, J. M.
- Affiliations
- Memorial University of Newfoundland (CA)
- University of British Columbia (CA)
- MRC Clinical Trials Unit at UCL (GB)
- Venue
- The Journal of Clinical Psychiatry
- Publisher
- Physicians Postgraduate Press, Inc
- Published
- 2019-07-23
- Volume
- 80
- Issue
- 4
- ISSN
- 0160-6689 (ISSN-L)
- 1555-2101
- PMC
- PMC6839961
- OpenAlex
- W2964029936
- Cited by
- 609
- References
- 119
- Citations by year
- 2026: 98 · 2025: 124 · 2024: 109 · 2023: 98 · 2022: 86 · 2021: 67 · 2020: 22 · 2019: 3
- FWCI
- 40.98
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- The Journal of Clinical Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Funders
- Medical Research Council (MC_UU_12023/21)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Maternal and Neonatal Healthcare
- Keywords
- anxiety disorders, pregnancy, postpartum period, perinatal anxiety, prevalence, post-traumatic stress disorder, specific phobia, parity, study heterogeneity, anxiety screening, obstetrics and gynecology
- MeSH terms
- Anxiety Disorders, Bayes Theorem, Female, Humans, Pregnancy, Pregnancy Complications, Puerperal Disorders, Prevalence
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