Demographic and Clinical Characteristics of Individuals in a Bipolar Disorder Case Registry
Abstract
BACKGROUND: The goal of this analysis was to characterize a cohort of 3000 persons who self-identified as having bipolar disorder by demographic, clinical, and treatment characteristics and to document the burden that this disorder imposed on their lives. METHOD: The Stanley Center Bipolar Disorder Registry used a variety of recruitment methods to reach people with bipolar disorder. The cohort included those currently in treatment and those active in support groups. Registrants completed an interviewer-administered questionnaire to obtain information on demographic characteristics, clinical history, and treatment history. RESULTS: The median age of the 2839 patients who were analyzed was 40.1 years, 64.5% were women, and over 90% were white. The median age at onset was 17.5 years, and the mean was 19.8 years. Despite the fact that over 60% completed at least some college and 30% completed college, 64% were currently unemployed. The patients' family histories point to a high prevalence of mental disorder in the families, especially mood disorders. Patients were concurrently taking multiple medications, and more than one third were taking at least 3 types of psychotropic medications. This pattern of pharmacotherapy was consistent with participants' overall mood ratings, which demonstrated how unusual it was for them to be symptom-free over a 6-month period. CONCLUSION: Our present findings point to the chronicity and severity of bipolar disorder as experienced in the community. We still need to develop better interventions, ensure access to care consistent with current consensus guidelines, and initiate care as early as possible in the course of the condition.
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A random sample of people who registered to join a BD care registry (n = 100) found that 93% met DSM-IV criteria for lifetime BD following a face-to-face structured clinical interview.
“a random sample of people who registered to join a BD care registry (n = 100) found that 93% met DSM-IV criteria for lifetime BD following a face-to-face structured clinical interview.”
From Evaluating the quality, safety, and functionality of commonly used smartphone apps for bipolar disorder mood and sleep self-management (2022) · cites this paper as Kupfer et al. 2002
Cites
Davenport, Y. B., Adland, M. L., Gold, P. W., & Goodwin, F. K. (1984) · The Lancet · doi:10.1016/s0140-6736(84)92810-1 · Cited by 2,925 · see citing works
Psychiatric disorders in America: the epidemiologic catchment area study
(1991) · Choice Reviews Online · doi:10.5860/choice.28-5931 · Cited by 2,561 · see citing works
Affective disorders in five United States communities
Weissman, M. M., Leaf, P. J., Tischler, G. L., Blazer, D. G., Karno, M., BRUCE, M. L., & Florio, L. P. (1988) · Psychological Medicine · doi:10.1017/s0033291700001975 · Cited by 625 · see citing works
The epidemiology of DSM-III-R bipolar I disorder in a general population survey
Kessler, R. C., Rubinow, D. R., Holmes, C. A., Abelson, J. M., & Zhao, S. (1997) · Psychological Medicine · doi:10.1017/s0033291797005333 · Cited by 600 · see citing works
Recruitment for controlled clinical trials: Literature summary and annotated bibliography
Lovato, L., Hill, K., Hertert, S., Hunninghake, D. B., & Probstfield, J. L. (1997) · Controlled Clinical Trials · doi:10.1016/s0197-2456(96)00236-x · Cited by 400 · see citing works
The Expert Consensus Guideline Series: Medication Treatment of Bipolar Disorder 2000.
Sachs, G. S., PRINTZ, D. J., Kahn, D. A., Carpenter, D. P., & Docherty, J. P. (2000) · PubMed · Cited by 394 · see citing works
Course and outcome in bipolar affective disorder: a longitudinal follow- up study
Goldberg, J. F., Harrow, M., & Grossman, L. S. (1995) · American Journal of Psychiatry · doi:10.1176/ajp.152.3.379 · Cited by 373 · see citing works
Rural-urban differences in depression treatment and suicidality.
Rost, K., Zhang, M.-L., Fortney, J., Smith, J. L., & Smith, G. (1998) · Medical Care · doi:10.1097/00005650-199807000-00015 · Cited by 142 · see citing works
Premorbid personality traits of men who develop unipolar or bipolar disorders
Clayton, P. J., Ernst, C., & Angst, J. (1994) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/bf02195728 · Cited by 135 · see citing works
Bipolar disorders : clinical course and outcome
Goldberg, J. F., & Harrow, M. (1999) · Cited by 86 · see citing works
Diagnostic certainty of a voluntary bipolar disorder case registry
Cluss, P. A., Marcus, S. C., Kelleher, K. J., Thase, M. E., Arvay, L. A., & Kupfer, D. J. (1999) · Journal of Affective Disorders · doi:10.1016/s0165-0327(98)00049-4 · Cited by 21 · see citing works
Self-citation
Flagged first, then by citations
1 of the 12 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Merikangas, K. R., Akiskal, H. S., Angst, J., Greenberg, P. E., Hirschfeld, R. M. A., Petukhova, M., & Kessler, R. C. (2007) · Archives of General Psychiatry · doi:10.1001/archpsyc.64.5.543 · Cited by 2,399 · see citing works
National Trends in the Outpatient Diagnosis and Treatment of Bipolar Disorder in Youth
Moreno, C., Laje, G., Blanco, C., Jiang, H., Schmidt, A. B., & Olfson, M. (2007) · Archives of General Psychiatry · doi:10.1001/archpsyc.64.9.1032 · Cited by 717 · see citing works
Perlis, R. H., Ostacher, M. J., Patel, J. K., Marangell, L. B., Zhang, H., Wisniewski, S. R., Ketter, T. A., Miklowitz, D. J., Otto, M. W., Gyulai, L., et al. (2006) · American Journal of Psychiatry · doi:10.1176/appi.ajp.163.2.217 · Cited by 689 · see citing works
Yatham, L. N., Kennedy, S. H., O'Donovan, C., Parikh, S., MacQueen, G., McIntyre, R., Sharma, V., Silverstone, P., Alda, M., Baruch, P., et al. (2005) · Bipolar Disorders · doi:10.1111/j.1399-5618.2005.00219.x · Cited by 388 · see citing works
Empirical evidence for discrete neurocognitive subgroups in bipolar disorder: clinical implications
Burdick, K. E., Russo, M., Frangou, S., Mahon, K., Braga, R. J., Shanahan, M. R., & Malhotra, A. K. (2014) · Psychological Medicine · doi:10.1017/s0033291714000439 · Cited by 355 · see citing works
Akiskal, H. S., Benazzi, F., Perugi, G., & Rihmer, Z. (2005) · Journal of Affective Disorders · doi:10.1016/j.jad.2004.12.004 · Cited by 346 · see citing works
Disability and its treatment in bipolar disorder patients
Huxley, N. A., & Baldessarini, R. J. (2007) · Bipolar Disorders · doi:10.1111/j.1399-5618.2007.00430.x · Cited by 263 · see citing works
Hunt, G. E., Malhi, G. S., Cleary, M., Lai, H. M. X., & Sitharthan, T. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.07.011 · Cited by 242 · see citing works
Calabrese, J. R., Huffman, R., White, R. L., Edwards, S., Thompson, T. R., Ascher, J. A., Monaghan, E., & Leadbetter, R. A. (2008) · Bipolar Disorders · doi:10.1111/j.1399-5618.2007.00500.x · Cited by 243 · see citing works
The economic burden of bipolar I disorder in the United States in 2015
Cloutier, M., Greene, M., Guerin, A., Touya, M., & Wu, E. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.09.011 · Cited by 215 · see citing works
Hafeman, D. M., Merranko, J., Axelson, D., Goldstein, B. I., Goldstein, T., Monk, K., Hickey, M. B., Sakolsky, D., Diler, R., Iyengar, S., et al. (2016) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2015.15040414 · Cited by 212 · see citing works
Self-citationMiskowiak, K. W., Burdick, K. E., Martínez‐Arán, A., Bonnín, C. D. M., Bowie, C. R., Carvalho, A., Gallagher, P., Lafer, B., López‐Jaramillo, C., Sumiyoshi, T., et al. (2018) · Bipolar Disorders · doi:10.1111/bdi.12595 · Cited by 213 · see citing works
Rheenen, T. E. V., Meyer, D., Neill, E., Phillipou, A., Tan, E. J., Toh, W. L., & Rossell, S. L. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.06.037 · Cited by 216 · see citing works
Epidemiology of Bipolar Disorders
Bauer, M., & Pfennig, A. (2005) · Epilepsia · doi:10.1111/j.1528-1167.2005.463003.x · Cited by 199 · see citing works
Personal Informatics in Interpersonal Contexts
Murnane, E. L., Walker, T., Tench, B., Voida, S., & Snyder, J. (2018) · Proceedings of the ACM on Human-Computer Interaction · doi:10.1145/3274396 · Cited by 196 · see citing works
Frank, E., Soreca, I., Swartz, H. A., Fagiolini, A. M., Mallinger, A. G., Thase, M. E., Grochocinski, V. J., Houck, P. R., & Kupfer, D. J. (2008) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2008.07121953 · Cited by 168 · see citing works
Self-citationInsurance Expenditures on Bipolar Disorder: Clinical and Parity Implications
Peele, P. B., Xu, Y., & Kupfer, D. J. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.7.1286 · Cited by 162 · see citing works
Self-citationMood and Anxiety Disorders in Chronic Headache
Baskin, S. M., Lipchik, G. L., & Smitherman, T. A. (2006) · Headache The Journal of Head and Face Pain · doi:10.1111/j.1526-4610.2006.00559.x · Cited by 159 · see citing works
Beesdo‐Baum, K., Höfler, M., Leibenluft, E., Lieb, R., Bauer, M., & Pfennig, A. (2009) · Bipolar Disorders · doi:10.1111/j.1399-5618.2009.00738.x · Cited by 158 · see citing works
Improving Functioning, Quality of Life, and Well-being in Patients With Bipolar Disorder
Bonnín, C. D. M., Reinares, M., Martínez‐Arán, A., Jiménez, E., Sánchez‐Moreno, J., Solé, B., Montejo, L., & Vieta, E. (2019) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyz018 · Cited by 154 · see citing works
Morselli, P. L., & Elgie, R. (2003) · Bipolar Disorders · doi:10.1034/j.1399-5618.2003.00037.x · Cited by 154 · see citing works
Murnane, E. L., Cosley, D., Chang, P., Guha, S., Frank, E., Gay, G., & Matthews, M. (2016) · Journal of the American Medical Informatics Association · doi:10.1093/jamia/ocv165 · Cited by 134 · see citing works
Self-citationGunderson, J. G. (2006) · American Journal of Psychiatry · doi:10.1176/appi.ajp.163.7.1173 · Cited by 148 · see citing works
Relationship of Birth Cohort and Early Age at Onset of Illness in a Bipolar Disorder Case Registry
Chengappa, K. N. R., Kupfer, D. J., Frank, E., Houck, P. R., Grochocinski, V. J., Cluss, P. A., & Stapf, D. A. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.9.1636 · Cited by 148 · see citing works
Self-citationMantere, O., Suominen, K. H., Leppämäki, S., Valtonen, H., Arvilommi, P., & Isometsä, E. T. (2004) · Bipolar Disorders · doi:10.1111/j.1399-5618.2004.00140.x · Cited by 146 · see citing works
Jensen, J. H., Støttrup, M. M., Nayberg, E., Knorr, U. B., Ullum, H., Purdon, S. E., Kessing, L. V., & Miskowiak, K. W. (2015) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.07.039 · Cited by 134 · see citing works
Gunderson, J. G., Weinberg, I., Daversa, M. T., Kueppenbender, K. D., Zanarini, M. C., Shea, M. T., Skodol, A. E., Sanislow, C. A., Yen, S., Morey, L. C., et al. (2006) · American Journal of Psychiatry · doi:10.1176/ajp.2006.163.7.1173 · Cited by 132 · see citing works
Macfarlane, A., & Greenhalgh, T. (2018) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-018-1842-x · Cited by 121 · see citing works
Prevalence and clinical features associated with bipolar disorder polypharmacy: a systematic review
Fornaro, M., Berardis, D. D., Koshy, A. S., Perna, G., Vancampfort, D., Stubbs, B., & Valchera, A. (2016) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s100846 · Cited by 115 · see citing works
Morselli, P. L., Elgie, R., & Cesana, B. (2004) · Bipolar Disorders · doi:10.1111/j.1399-5618.2004.00160.x · Cited by 113 · see citing works
Onset-age of bipolar disorders at six international sites☆
Baldessarini, R. J., Bolzani, L., Cruz, N., Jones, P. B., Lai, M., Lepri, B., Pérez, J., Salvatore, P., Tohen, M. F., & Tondo, L. (2009) · Journal of Affective Disorders · doi:10.1016/j.jad.2009.05.030 · Cited by 114 · see citing works
Quittkat, H. L., Düsing, R., Holtmann, F., Buhlmann, U., Svaldi, J., & Vocks, S. (2020) · Frontiers in Psychology · doi:10.3389/fpsyg.2020.586246 · Cited by 112 · see citing works
Safety and Tolerability of Lamotrigine for Bipolar Disorder
Bowden, C. L., Asnis, G. M., Ginsberg, L. D., Bentley, B., Leadbetter, R. A., & White, R. (2004) · Drug Safety · doi:10.2165/00002018-200427030-00002 · Cited by 110 · see citing works
Subthreshold bipolarity: diagnostic issues and challenges
Nusslock, R., & Frank, E. (2011) · Bipolar Disorders · doi:10.1111/j.1399-5618.2011.00957.x · Cited by 109 · see citing works
Self-citationShi, L. (2004) · Journal of Affective Disorders · doi:10.1016/j.jad.2004.03.009 · Cited by 98 · see citing works
Polytherapy in Bipolar Disorder
Lin, D., Mok, H., & Yatham, L. N. (2006) · CNS Drugs · doi:10.2165/00023210-200620010-00003 · Cited by 91 · see citing works
Alloy, L. B., Abramson, L. Y., Walshaw, P. D., Keyser, J. D., & Gerstein, R. K. (2006) · Development and Psychopathology · doi:10.1017/s0954579406060524 · Cited by 90 · see citing works
Bipolar disorder: disease burden.
Sajatovic, M. (2005) · PubMed · Cited by 90 · see citing works
Depression with racing thoughts
Benazzi, F. (2003) · Psychiatry Research · doi:10.1016/s0165-1781(03)00198-7 · Cited by 91 · see citing works
Management of comorbid bipolar disorder and substance use disorders
Salloum, I. M., & Brown, E. S. (2017) · The American Journal of Drug and Alcohol Abuse · doi:10.1080/00952990.2017.1292279 · Cited by 91 · see citing works
Elgie, R., & Morselli, P. L. (2007) · Bipolar Disorders · doi:10.1111/j.1399-5618.2007.00339.x · Cited by 88 · see citing works
Pålsson, E., Figueras, C., Johansson, A. G. M., Ekman, C. J., Hultman, B., Östlind, J., & Landén, M. (2013) · BMC Psychiatry · doi:10.1186/1471-244x-13-165 · Cited by 88 · see citing works
Age at onset in bipolar I affective disorder in the USA and Europe
Bellivier, F., Etain, B., Malafosse, A., Henry, C., Kahn, J.-P., Elgrabli-Wajsbrot, O., Jamain, S., Azorin, J.-M., Frank, E., Scott, J., et al. (2014) · The World Journal of Biological Psychiatry · doi:10.3109/15622975.2011.639801 · Cited by 86 · see citing works
Self-citationJones, S. H., Mansell, W., & Waller, L. (2006) · Journal of Affective Disorders · doi:10.1016/j.jad.2006.01.017 · Cited by 84 · see citing works
Suppes, T. M., Eudicone, J. M., McQuade, R. D., Pikalov, A., & Carlson, B. X. (2007) · Journal of Affective Disorders · doi:10.1016/j.jad.2007.08.015 · Cited by 84 · see citing works
Is preadolescent mania the same condition as adult mania? A British perspective
Harrington, R., & Myatt, T. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00315-9 · Cited by 83 · see citing works
Proudfoot, J. G., Jayawant, A., Whitton, A. E., Parker, G. B., Manicavasagar, V. L., Smith, M., & Nicholas, J. (2012) · BMC Psychiatry · doi:10.1186/1471-244x-12-196 · Cited by 82 · see citing works
Rietdijk, J., Klaassen, R. M. C., Ising, H. K., Dragt, S., Nieman, D. H., van de Kamp, J., Cuijpers, P. J., Linszen, D. H., & van der Gaag, M. (2012) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2012.01839.x · Cited by 81 · see citing works
Nusslock, R., Young, C. B., & Damme, K. S. F. (2014) · Behaviour Research and Therapy · doi:10.1016/j.brat.2014.08.011 · Cited by 79 · see citing works
Overcoming barriers to reducing the burden of affective disorders
Wells, K. B., Miranda, J. M., Bauer, M. S., BRUCE, M. L., Durham, M., Escobar, J. I., Ford, D. E., Gonzalez, J., Hoagwood, K., Horwitz, S. M., et al. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01403-8 · Cited by 76 · see citing works
Morton, E., Sakai, K., Ashtari, A., Pleet, M., Michalak, E. E., & Woolley, J. (2023) · Journal of Psychopharmacology · doi:10.1177/02698811221131997 · Cited by 78 · see citing works
Grande, I., Goikolea, J. M., Dios, C. D., González-Pinto, A. M., Montes, J. M. G., Sáiz‐Ruiz, J., Prieto, E., Vieta, E., & for the PREBIS group (2012) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.12003 · Cited by 78 · see citing works
Wong, E. H. F., Tarazi, F. I., & Shahid, M. (2010) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2010.02.001 · Cited by 75 · see citing works
Early Onset Bipolar Disorder: Clinical and Research Considerations
Carlson, G. A. (2005) · Journal of Clinical Child & Adolescent Psychology · doi:10.1207/s15374424jccp3402_13 · Cited by 74 · see citing works
Haro, J. M., van Os, J., Vieta, E., Reed, C. C., Lorenzo, M. M., GOETZ, I. A., & the EMBLEM Advisory Board (2005) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2005.00692.x · Cited by 74 · see citing works
Carlborg, A., Ferntoft, L., Thuresson, M., & Bodegård, J. (2014) · Bipolar Disorders · doi:10.1111/bdi.12234 · Cited by 71 · see citing works
Antidepressants and suicidal behavior in bipolar disorder
McElroy, S. L., Kotwal, R., Kaneria, R., & Keck, P. E. (2006) · Bipolar Disorders · doi:10.1111/j.1399-5618.2006.00348.x · Cited by 71 · see citing works
Maripuu, M., Wikgren, M., Karling, P., Adolfsson, R., & Norrback, K. (2014) · PLoS ONE · doi:10.1371/journal.pone.0098682 · Cited by 67 · see citing works
Age at onset in 3014 Sardinian bipolar and major depressive disorder patients
Tondo, L., Lepri, B., Cruz, N., & Baldessarini, R. J. (2009) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2009.01523.x · Cited by 67 · see citing works
Berk, M., & Dodd, S. (2005) · Medical Hypotheses · doi:10.1016/j.mehy.2005.02.010 · Cited by 67 · see citing works
Negash, A. A., Alem, A., Kebede, D., Deyessa, N., Shibre, T., & Kullgren, G. (2005) · Journal of Affective Disorders · doi:10.1016/j.jad.2005.03.011 · Cited by 66 · see citing works
Factors associated with functional recovery in bipolar disorder patients
Wingo, A. P., Baldessarini, R. J., Holtzheimer, P. E., & Harvey, P. D. (2010) · Bipolar Disorders · doi:10.1111/j.1399-5618.2010.00808.x · Cited by 66 · see citing works
The structure of lifetime manic–hypomanic spectrum
Cassano, G. B., Mula, M., Rucci, P., Miniati, M., Frank, E., Kupfer, D. J., Oppo, A., Calugi, S., Maggi, L., Gibbons, R. D., et al. (2008) · Journal of Affective Disorders · doi:10.1016/j.jad.2008.04.019 · Cited by 65 · see citing works
Self-citationIdentifying Difficult-to-Treat Depression
Gaynes, B. N. (2009) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.8133su1c.02 · Cited by 64 · see citing works
O’Donnell, L. A., Deldin, P. J., Grogan‐Kaylor, A. C., McInnis, M. G., Weintraub, J., Ryan, K. A., & Himle, J. A. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.03.015 · Cited by 63 · see citing works
Classifying mood disorders by age-at-onset instead of polarity
Benazzi, F. (2008) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2008.10.007 · Cited by 62 · see citing works
McKnight, R. F., Bilderbeck, A. C., Miklowitz, D. J., Hinds, C., Goodwin, G. M., & Geddes, J. R. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.07.029 · Cited by 58 · see citing works
Citalopram as Adjunctive Therapy in Bipolar Depression
Kupfer, D. J., Chengappa, K. N. R., Gelenberg, A. J., Hirschfeld, R. M. A., Goldberg, J. F., Sachs, G. S., Grochocinski, V. J., Houck, P. R., & Kolar, A. B. (2001) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v62n1212 · Cited by 58 · see citing works
Self-citationRisks associated with gender differences in bipolar I disorder
Azorin, J., Belzeaux-R, R., Kaladjian, A., Adida, M., Hantouche, E. G., Lancrenon, S., & Fakra, É. (2013) · Journal of Affective Disorders · doi:10.1016/j.jad.2013.08.031 · Cited by 57 · see citing works
The course of bipolar disorder
Saunders, K. E. A., & Goodwin, G. M. (2010) · Advances in Psychiatric Treatment · doi:10.1192/apt.bp.107.004903 · Cited by 56 · see citing works
Frangou, S., Raymont, V., & Bettany, D. (2002) · Bipolar Disorders · doi:10.1034/j.1399-5618.2002.01223.x · Cited by 56 · see citing works
Kennedy, S. H., & Lam, R. W. M. (2003) · Bipolar Disorders · doi:10.1111/j.1399-2406.2003.00058.x · Cited by 53 · see citing works
Tamayo, J. M., Zarate, C. A., Vieta, E., Vázquez, G. H., & Tohen, M. F. (2010) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145709991246 · Cited by 56 · see citing works
Bauer, M. S., Unützer, J., Pincus, H. A., & Lawson, W. B. (2002) · Mental Health Services Research · doi:10.1023/a:1020968616616 · Cited by 55 · see citing works
Bipolar depression: the real challenge
Hirschfeld, R. M. A. (2004) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2004.03.001 · Cited by 54 · see citing works
The role of atypical antipsychotics in bipolar depression and anxiety disorders
McIntyre, R. S., & Katzman, M. A. (2003) · Bipolar Disorders · doi:10.1111/j.1399-2406.2003.00061.x · Cited by 54 · see citing works
Salivary cortisol secretion in remitted bipolar patients and offspring of bipolar parents
Deshauer, D., Duffy, A., Meaney, M., Sharma, S., & Grof, P. (2006) · Bipolar Disorders · doi:10.1111/j.1399-5618.2006.00338.x · Cited by 53 · see citing works
Use of Health Care Services Among Persons Who Screen Positive for Bipolar Disorder
Frye, M. A., Calabrese, J. R., Reed, M. L., Wagner, K. D., Lewis, L., McNulty, J. P., & Hirschfeld, R. M. A. (2005) · Psychiatric Services · doi:10.1176/appi.ps.56.12.1529 · Cited by 52 · see citing works
Bipolar disorder and work loss.
Bowden, C. L. (2005) · PubMed · Cited by 52 · see citing works
Matthews, M. L., Murnane, E. L., & Snyder, J. (2017) · Human-Computer Interaction · doi:10.1080/07370024.2017.1294983 · Cited by 50 · see citing works
Treatment Research in Bipolar Disorder
Baldessarini, R. J. (2002) · CNS Drugs · doi:10.2165/00023210-200216110-00001 · Cited by 51 · see citing works
The Role of Psychomotor Activation in Discriminating Unipolar From Bipolar Disorders
Cassano, G. B., Rucci, P., Benvenuti, A., Miniati, M., Calugi, S., Maggi, L., Pini, S., Kupfer, D. J., Maj, M., Fagiolini, A. M., et al. (2012) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.11m06946 · Cited by 49 · see citing works
Self-citationCrowe, M., Whitehead, L., Wilson, L., Carlyle, D., O'Brien, A. J., Inder, M., & Joyce, P. R. (2010) · International Journal of Nursing Studies · doi:10.1016/j.ijnurstu.2010.02.012 · Cited by 49 · see citing works
Machado‐Vieira, R., Luckenbaugh, D. A., Ballard, E. D., Henter, I. D., Tohen, M. F., Suppes, T. M., & Zarate, C. A. (2016) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2016.15091132 · Cited by 49 · see citing works
Supporting Self-Management in Bipolar Disorder: Mixed-Methods Knowledge Translation Study
Michalak, E. E., Morton, E. E., Barnes, S. J., Hole, R., CREST.BD, & Murray, G. (2019) · JMIR Mental Health · doi:10.2196/13493 · Cited by 48 · see citing works
Major Depressive Disorder with Anger: A Bipolar Spectrum Disorder?
Benazzi, F. (2003) · Psychotherapy and Psychosomatics · doi:10.1159/000073026 · Cited by 48 · see citing works
Neurosyphilis presenting as mania
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Calabrese, J. R., Muzina, D. J., Kemp, D. E., Sachs, G. S., Frye, M. A., Thompson, T. R., Klingman, D., Reed, M. L., & Hirschfeld, R. M. A. (2006) · PubMed Central · Cited by 45 · see citing works
Baethge, C., Baldessarini, R. J., Mathiske-Schmidt, K., Hennen, J. A., Berghöfer, A., Müller-Oerlinghausen, B., Bschor, T., Adli, M., & Bauer, M. (2005) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v66n0204 · Cited by 46 · see citing works
Agitated depression: a valid depression subtype?
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Bipolar Disorder: A National Health Concern
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Raymont, V., Bettany, D., & Frangou, S. (2003) · European Psychiatry · doi:10.1016/s0924-9338(02)00009-3 · Cited by 41 · see citing works
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Bauer, M., Glenn, T., Alda, M., Andreassen, O. A., Angelopoulos, E., Ardau, R., Baethge, C., Bauer, R., Bellivier, F., Belmaker, R. H., et al. (2015) · European Psychiatry · doi:10.1016/j.eurpsy.2014.10.005 · Cited by 39 · see citing works
Work impairment in bipolar disorder patients – results from a two-year observational study (EMBLEM)
Reed, C. C., GOETZ, I. A., Vieta, E., Bassi, M., Haro, J. M., & the EMBLEM Advisory Board (2010) · European Psychiatry · doi:10.1016/j.eurpsy.2010.01.001 · Cited by 39 · see citing works
- Authors
- Kupfer, D. J., Frank, E., Grochocinski, V. J., Cluss, P. A., Houck, P. R., & Stapf, D. A.
- Affiliations
- University of Pittsburgh (US)
- Venue
- The Journal of Clinical Psychiatry
- Publisher
- Physicians Postgraduate Press, Inc
- Published
- 2002-02-15
- Volume
- 63
- Issue
- 2
- Pages
- 120-125
- ISSN
- 0160-6689 (ISSN-L)
- OpenAlex
- W2032307757
- Cited by
- 294
- References
- 12
- Citations by year
- 2026: 5 · 2025: 3 · 2024: 3 · 2023: 6 · 2022: 9 · 2021: 10 · 2020: 13 · 2019: 7 · 2018: 11 · 2017: 13 · 2016: 11 · 2015: 6 · 2014: 10 · 2013: 9 · 2012: 14
- FWCI
- 13.22
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Clinical Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (MH30915)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Keywords
- bipolar disorder, case registry, demographic factors, clinical features, treatment history, age of onset, unemployment, family history of mood disorders, access to mental health care, early intervention
- MeSH terms
- Adolescent, Adult, Bipolar Disorder, Drug Therapy, Combination, Educational Status, Family, Female, Health Status, Humans, Male, Pennsylvania, Psychotropic Drugs, Registries, Unemployment, Cohort Studies, Prevalence, Cost of Illness, Age of Onset, Polypharmacy
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