A review of butyrylcholinesterase as a therapeutic target in the treatment of Alzheimer’s disease
Nordberg, Agneta, Ballard, Clive, Bullock, Roger, Darreh-Shori, Taher, Somogyi, Monique·2013·The Primary Care Companion For CNS Disorders
Cited by (351)
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- Microorganism-Derived Molecules as Enzyme Inhibitors to Target Alzheimer’s Diseases PathwaysThi Hanh Nguyen, San‐Lang Wang, Van Bon Nguyen · 2023 · Pharmaceuticals
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- Application of Green Technologies in Design-Based Extraction of Celastrus paniculatus (Jyotishmati) Seeds, SEM, GC-MS Analysis, and Evaluation for Memory Enhancing PotentialAshwani Arya, Deepak Kumar Kaushik, Rafa Almeer, SIMONA GABRIELA BUNGAU, Amany Ahmed Sayed, Mohamed M. Abdel‐Daim, Saurabh Bhatia, Vineet Mittal · 2022 · Frontiers in Nutrition
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- Dual anti-cholinesterase activity of ajoene by In silico and In vitro studiesSuresh Kumar, Shivani Kumar, Sayan Chatterjee · 2018 · Pharmacognosy Research
- Privileged multi-target directed propargyl-tacrines combining cholinesterase and monoamine oxidase inhibition activitiesŽofia Chrienová, Eugenie Nepovimová, Rudolf Andrýs, Rafael Doležal, Jana Janočková, Ľubica Múčková, Lenka Fabova, Ondřej Soukup, Patrik Olekšák, Martin Vališ et al. · 2022 · Journal of Enzyme Inhibition and Medicinal Chemistry
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- Computational and ADMET Predictions of Novel Compounds as Dual Inhibitors of BuChE and GSK-3β to Combat Alzheimer’s DiseaseSaurabh G. Londhe, Vinayak S. Walhekar, Selanere S. Mangala, Suvarna G. Kini, Marcus Tullius Scotti, Luciana Scotti, Dileep Kumar · 2024 · Pharmaceutics
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- Oxidation at C-16 enhances butyrylcholinesterase inhibition in lupane triterpenoidsMaría Julia Castro, Victoria Richmond, María Belén Faraoni, Ana Paula Murray · 2018 · Bioorganic Chemistry
- Vitamin B3-Based Biologically Active Compounds as Inhibitors of Human CholinesterasesAntonio Zandona, Gabriela Lihtar, Nikola Maraković, Katarina Miš, Valentina Bušić, Dajana Gašo-Sokač, Sergej Pirkmajer, Maja Katalinić · 2020 · International Journal of Molecular Sciences