Cited by 29Endometriosis Research and TreatmentEctopic Pregnancy Diagnosis and ManagementGynecological conditions and treatments

Scar endometriosis

Open access
Pathan, ZaheerAbbas Ali Khan, Dinesh, US, Rao, Ravikala·2010·Journal of Cytology

Abstract

Endometriosis is the presence of functioning endometrium outside the uterus. Endometriosis rarely occurs in the abdominal wall. Majority of abdominal wall endometriosis occur in or adjacent to surgical scars, following caesarean section or hysterectomy. Laparotomy scar endometriosis following salpingectomy for ectopic pregnancy has rarely been reported. We report a case of scar endometriosis following laparotomy for chronic ectopic, and diagnosed by fine needle aspiration cytology (FNAC). Excision biopsy confirmed the FNAC diagnosis of scar endometriosis.

AI snapshot

Written from the paper’s full text.

TL;DR

This case report describes a 28-year-old woman with scar endometriosis presenting as a painful lower abdominal wall nodule 3 years after laparotomy for chronic ectopic pregnancy. Fine needle aspiration cytology (FNAC) suggested endometriosis, and excision biopsy confirmed the diagnosis.

Key findings

  • A 28-year-old G2P1 woman presented with a 2-year history of a painful nodule over the lower abdominal wall after laparotomy for chronic ectopic 3 years earlier; examination showed a 3×3 cm firm, slightly tender subcutaneous nodule above a Pfannenstiel scar, and ultrasonography showed an ill-defined hypoechoic 21×16 mm subcutaneous lesion.
  • FNAC smears were cellular with monolayered sheets of polygonal epithelial cells, irregular stromal fragments of spindle cells, mixed inflammatory infiltrate, naked stromal nuclei, and occasional hemosiderin-laden macrophages in a hemorrhagic background; FNAC diagnosis was endometriosis.
  • Excision biopsy showed a 5×5 cm fibrofatty mass with a central fibrous grey-white area containing minute cystic spaces; microscopy showed variably dilated endometrial glands surrounded by spindle cell stroma, lymphoplasmacytic infiltrate, and hemosiderin-laden macrophages within fibrocollagenous tissue, confirming FNAC diagnosis.
  • The paper cites scar endometriosis incidence as 1.08% for mid-trimester abortion and 0.03–0.4% following caesarean sections, and notes Horton et al. reviewed 445 cases of abdominal wall endometriosis, with 57%, 11%, and 12% occurring in caesarean section, hysterectomy, and other surgical scars, respectively, and 20% not in scars.

Methods

  • Single case report of a 28-year-old woman with a painful abdominal wall nodule after prior laparotomy for chronic ectopic pregnancy.
  • Diagnostic evaluation included clinical examination, ultrasonography, FNAC, and subsequent excision biopsy with histopathology.
  • The report is descriptive, comparing cytological and histopathological findings with literature on scar endometriosis and its differential diagnosis.

Limitations

  • The paper does not state limitations.
  • Evident from the text: this is a single case report, so findings are not generalizable and no follow-up or recurrence data are reported.
  • Evident from the text: the literature discussion is narrative rather than a systematic review, and incidence figures are cited from prior studies rather than derived from this case.

Model-written summary. Check it against the paper before relying on it.

Integrity signals

Registry

Crossref · 10.4103/0970-9371.71877

Cites

9 of 9 references verified0 citation errors · 0 not checkable

Statistics

Nothing to recompute.

Claims the paper makes

0 of 22 cited sources checked · 0 supported · 0 flagged

  • Findingown data

    Excision biopsy confirmed the FNAC diagnosis of scar endometriosis.

    “The excised mass was composed of 5×5 cm fibrofatty tissue with central fibrous grey-white area containing minute cystic spaces [Figure 2a]. Microscopy showed variably dilated endometrial glands surrounded by spindle cell stroma, lymphoplasmacytic infiltrate and hemosiderin laden macrophages within fibrocollagenous tissue [Figure 2b], confirming the FNAC diagnosis of endometriosis.”
    Quote in the paperNot a substantial claim
  • Findingown data

    Ultrasonography revealed an ill-defined hypoechoic, 21×16 mm lesion in the subcutaneous plane.

    “Ultrasonography revealed an ill-defined hypoechoic, 21×16 mm lesion in the subcutaneous plane.”
    Quote in the paperNot a substantial claim
  • Findingown data

    Examination revealed a well-defined, 3×3 cm, firm and slightly tender nodule in the subcutaneous plane above the pfannenstiel scar.

    “Examination revealed a well-defined, 3×3 cm, firm and slightly tender nodule in the subcutaneous plane above the pfannenstiel scar.”
    Quote in the paperNot a substantial claim
  • Premisecitation

    Endometriosis in an operative scar is rare.

    “Endometriosis in an operative scar is rare.[25]”
    • Also stated in: § Abstract · plain
      “Endometriosis rarely occurs in the abdominal wall.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [25]

      Not checked in the free run.

  • Premisecitation

    Majority of reported cases of abdominal wall endometriosis occur in or adjacent to surgical scars, most commonly following caesarean section or hysterectomy.

    “Majority of the reported cases have been observed in and adjacent to surgical scars following caesarean sections, hysterectomy, hysterotomy and rarely following surgeries on fallopian tube, appendicectomy, amniocentesis and episiotomy.[8]”
    • Also stated in: § Abstract · plain
      “Majority of abdominal wall endometriosis occur in or adjacent to surgical scars, following caesarean section or hysterectomy.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [8] Goel, 2005, Indian J Med Sci

      Not checked in the free run.

  • May combine two claims. 14
  • Classified as probably not a substantial claim. 13
  • May combine two claims.

    Findingown data

    FNAC smears showed cytological features consistent with endometriosis, and a FNAC diagnosis of endometriosis was offered.

    “Based on these features, FNAC diagnosis of endometriosis was offered.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Findingown data

    The patient underwent laparotomy for chronic ectopic 3 years prior.

    “She underwent laparotomy for chronic ectopic 3 years prior.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Findingown data

    The patient was a 28-year-old G2P1 female who presented with a painful nodule of 2 years duration over the lower abdominal wall.

    “A 28-year-old (G2P1) female presented with a painful nodule of 2 years duration over the lower abdominal wall.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    Endometriosis of the skin and soft tissue constitutes 3.5% cases of extrapelvic endometriosis.

    “Endometriosis of the skin and soft tissue constitutes 3.5% cases of extrapelvic endometriosis.[6]”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [6] Catalina-Fernández, 2007, Acta Cytol

      Not checked in the free run.

  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    Extrapelvic endometriosis is an uncommon disorder with a prevalence of 8.9-15%.

    “Extrapelvic endometriosis is an uncommon disorder with a prevalence of 8.9–15%.[17]”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [17]

      Not checked in the free run.

  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Premisecitation

    In a study by Pathan et al., seven cases occurred in caesarean and one occurred in a hysterectomy scar.

    “In a study by Pathan et al.,[5] seven cases occurred in caesarean and one occurred in a hysterectomy scar.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [5] Pathan, 2005, Cytopathology

      Not checked in the free run.

  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    The treatment of choice is wide local excision.

    “The treatment of choice is wide local excision.[67]”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [67]

      Not checked in the free run.

  • May combine two claims.

    Premisecitation

    Cyclicity of symptoms during menstruation is not characteristically seen in all cases, however, if present, is pathognomonic of scar endometriosis.

    “Cyclicity of symptoms during menstruation is not characteristically seen in all cases, however, if present, is pathognomonic of scar endometriosis.[1]”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [1] Gajjar, 2008, Arch Gynecol Obstet

      Not checked in the free run.

  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    The presence of any two of the three components (endometrial glands, stromal cells and hemosiderin laden macrophages) has been used for the cytological diagnosis of endometriosis.

    “The presence of any two of the three components (endometrial glands, stromal cells and hemosiderin laden macrophages) has been used for the cytological diagnosis of endometriosis.[5]”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [5] Pathan, 2005, Cytopathology

      Not checked in the free run.

  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Premisecitation

    Horton et al. reviewed 445 cases of abdominal wall endometriosis, among which 57%, 11% and 12% occurred in scars of caesarean section, hysterectomy and other surgical procedures, respectively; 20% did not occur in the scar but elsewhere such as umbilicus and groin.

    “Horton et al.[3] reviewed 445 cases of abdominal wall endometriosis among which 57, 11 and 12% cases occurred in scars of caesarean section, hysterectomy and other surgical procedures, respectively. Twenty percent cases did not occur in the scar but elsewhere such as umbilicus and the groin.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [3] Horton, 2008, Am J Surg

      Not checked in the free run.

  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    The first case of scar endometriosis was reported by Meyer in 1903.

    “The first case of scar endometriosis was reported by Meyer in 1903.[9]”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [9] Agarwal, 2010, J Lab Physician

      Not checked in the free run.

  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Premisecitation

    Blanco et al. reported 10 cases of scar endometriosis, of which 9 followed caesarean section and one occurred in laparotomy for ectopic pregnancy.

    “Blanco et al.[7] reported 10 cases of scar endometriosis of which 9 cases followed caesarean section and one occurred in laparotomy for ectopic pregnancy.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [7] Blanco, 2003, Am J Surg

      Not checked in the free run.

  • May combine two claims.

    Premisecitation

    The incidence of endometriosis developing in the scar depends on the indication for the original surgery, being 1.08% for mid-trimester abortion and 0.03-0.4% following caesarean sections.

    “The incidence of endometriosis developing in the scar depends on the indication for the original surgery, being 1.08% for mid-trimester abortion and 0.03–0.4% following caesarean sections.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [78]

      Not checked in the free run.

  • May combine two claims.

    Premisecitation

    The imaging modalities are non-specific but useful in determining the extent of the disease and planning of operative resection, especially in recurrent and large lesions.

    “The imaging modalities are non-specific but useful in determining the extent of the disease and planning of operative resection, especially in recurrent and large lesions.[7]”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [7] Blanco, 2003, Am J Surg

      Not checked in the free run.

  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Premisecitation

    Squamous, tubal and mucinous metaplasia and isolated cases of malignant transformation in scar endometriosis have been reported.

    “Squamous, tubal and mucinous metaplasia and isolated cases of malignant transformation in scar endometriosis have been reported.[6]”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [6] Catalina-Fernández, 2007, Acta Cytol

      Not checked in the free run.

  • May combine two claims.

    Interpretationreasoning

    FNAC may be the only diagnostic tool in the evaluation of these lesions, providing rapid and accurate preoperative diagnosis.

    “So, FNAC may be the only diagnostic tool in the evaluation of these lesions, providing rapid and accurate preoperative diagnosis.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    The interval between onset of symptoms and patient's index surgery varies from 3 months to 10 years.

    “The interval between onset of symptoms and patient’s index surgery varies from 3 months to 10 years.[8]”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [8] Goel, 2005, Indian J Med Sci

      Not checked in the free run.

  • May combine two claims.

    Premisecitation

    Clinically, the features diagnostic of scar endometriosis are lump in the scar, pain, increasing size of lump, bleeding and skin discoloration.

    “Clinically, the features diagnostic of scar endometriosis are lump in the scar, pain, increasing size of lump, bleeding and skin discoloration.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [1] Gajjar, 2008, Arch Gynecol Obstet

      Not checked in the free run.

  • May combine two claims.

    Premisecitation

    Clinically, the lesion appears as a firm nodule and hence can be easily evaluated by FNAC.

    “Clinically, the lesion appears as a firm nodule and hence can be easily evaluated by FNAC.[7]”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [7] Blanco, 2003, Am J Surg

      Not checked in the free run.

  • May combine two claims.

    Interpretationnone given

    Patients usually present 2-5 years following uterine or fallopian tube surgery, with a painful nodule that may become more symptomatic during menstruation.

    “Patients usually present 2–5 years following uterine or fallopian tube surgery, with a painful nodule that may become more symptomatic during menstruation.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Interpretationnone given

    Scar endometriosis is an uncommon condition that primarily affects women of reproductive age.

    “Scar endometriosis is an uncommon condition that primarily affects women of reproductive age.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Interpretationreasoning

    FNAC is a relatively inexpensive, less traumatic, rapid and accurate diagnostic tool for diagnosis and to rule out other common conditions.

    “FNAC is a relatively inexpensive, less traumatic, rapid and accurate diagnostic tool for diagnosis and to rule out other common conditions.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    Abdominal wall musculature involvement requires en bloc resection of the myofascial elements.

    “Abdominal wall musculature involvement requires en bloc resection of the myofascial elements.[3]”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [3] Horton, 2008, Am J Surg

      Not checked in the free run.

23 of 23
  • The paper relies on this without support.

    Laparotomy scar endometriosis following salpingectomy for ectopic pregnancy has rarely been reported.

    “Laparotomy scar endometriosis following salpingectomy for ectopic pregnancy has rarely been reported.”
1 of 1

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • The diagnosis of endometriosis might be challenging, and several differential diagnoses might exist for a mass in the abdominal wall, including desmoid tumour, fibrosis, suture granuloma, fat necrosis, nodular fasciitis, and primary or metastatic malignancies.

    “The diagnosis of this disease might be challenging and several differential diagnoses might exist for a mass in the abdominal wall, including desmoid tumour, fibrosis, suture granuloma, fat necrosis, nodular fasciitis and primary or metastatic malignancies lesions [15].”
  • Fine needle aspiration cytology (FNAC) can be helpful before surgery and can be used for determining all three criteria of endometriosis.

    “Using of fine needle aspiration cytology (FNAC) can be helpful before the surgery and can be used for determining all three criterion of endometriosis [15]”

Cites

Flagged first, then by citations

Research works printed but not linked: 1

  1. Fulciniti, 2005, Fine needle aspiration cytology of endometriosis: experience with 10 cases, Acta Cytol, 495

Cited by

Sorted by citations

Authors
Pathan, Z. A. K., Dinesh, U., & Rao, R.
Venue
Journal of Cytology
Published
2010
Volume
27
Issue
3
Pages
106
ISSN
0970-9371 (ISSN-L)
OpenAlex
W4234869260
Cited by
29
References
8
Citations by year
2025: 2 · 2023: 4 · 2021: 3 · 2020: 2 · 2019: 1 · 2018: 3 · 2017: 1 · 2016: 2 · 2015: 4 · 2014: 4 · 2012: 1
FWCI
1.14
Type
journal article
Language
en
Open access
Licence
cc-by-nc-sa
Locations
  • Journal of Cytology (publishedVersion, cc-by-nc-sa)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics
  • Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ectopic Pregnancy Diagnosis and Management
  • Health Sciences › Medicine › Obstetrics and Gynecology › Gynecological conditions and treatments
Keywords
scar endometriosis, abdominal wall endometriosis, laparotomy scar, chronic ectopic pregnancy, salpingectomy, fine needle aspiration cytology, excisional biopsy, ectopic pregnancy

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