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Curcumin and Apigenin - novel and promising therapeutics against chronic neuroinflammation in Alzheimer's disease

Münch, Gerald, Venigalla, Madhuri, Sonego, Sandra, Gyengesi, Erika·2015·Neural Regeneration Research
DOI 10.4103/1673-5374.162686PMC PMC4590215
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Crossref · 10.4103/1673-5374.162686

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  • ERK signaling has been linked to the cognitive-enhancing effects of plant secondary metabolites, such as curcumin and apigenin.

    “Along these lines, it is intriguing that ERK signaling has been linked to the cognitive-enhancing effects of plant secondary metabolites, such as curcumin and apigenin.46,47”

    From TERT activation targets DNA methylation and multiple aging hallmarks (2024) · cites this paper as [47]

    The Apigenin > Animal studies section reports improved learning and memory in apigenin-treated Alzheimer’s-model mice alongside restoration of a cortical ERK/CREB/BDNF pathway involved in learning and memory. The Curcumin > Mechanistic pathways and cellular studies section separately describes memory-enhancing actions and MAPK-related anti-inflammatory effects, but does not link ERK signaling to curcumin’s cognitive effects. (LLM, conf=0.87)

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Research works printed but not linked: 57

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Metadata

Authors
Münch, G., Venigalla, M., Sonego, S., & Gyengesi, E.
Venue
Neural Regeneration Research
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2015
Volume
10
Issue
8
Pages
1181
ISSN
1673-5374
DOI
10.4103/1673-5374.162686
PMC
PMC4590215
Cited by
160
References
4
Language
en

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