The effect of counseling based on acceptance and commitment therapy on mental health and quality of life among infertile couples: a randomized controlled trial
Open accessAbstract
INTRODUCTION: Infertility by creating a disturbing and debilitating condition is considered as an important individual, public, and social health problem. The purpose of this study was to determine the effect of counseling based on acceptance and commitment therapy (ACT) on mental health and quality of life in infertile couples. METHODS: In this randomized controlled trial, 54 infertile couples referring to the Sanandaj-Iran Infertility Clinic were assigned into two groups of counseling and control by random blocking with a 1:1 ratio. The consulting group received 8 weekly 90-min sessions of group counseling based on ACT. The General Health Questionnaire-28 (GHQ-28) and Fertility Quality of Life were completed before and 1 month after the completion of the intervention. Primary outcome measures were mean score of mental health and quality of fertility life. Independent t -test, ANCOVA, and Mann–Whitney U-test were used to analyze data. RESULTS: There was no significant intergroup difference in demographic information ( P > 0.05). One month after the end of the intervention, the mean overall mental health score in the couples of the counseling group was significantly less than the control group (adjusted mean difference [aMD]: −8.4; 95% confidence interval [CI]: −10.4–−6.4; P < 0.001). Furthermore, the mean overall score of quality of life in the counseling group couples was significantly more than the control group (aMD: 14.8; 95% CI: 11.8–17.9; P < 0.001). CONCLUSION: Based on the effectiveness of counseling based on ACT on mental health and quality of life in infertile couples, it can be used in the infertility clinics. Health-care providers and counselors should train in the ACT courses to improve the mental health and quality of life of infertile couples.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Studies in the Middle East have applied ACT to infertility-related distress with promising results.
“To date, studies conducted in the Middle East have applied ACT to infertility-related distress with promising results,38–40 though it has yet to be tested in North America.”
From Infertility-related distress and clinical targets for psychotherapy: A qualitative study (2021) · cites this paper as [38]
There have been only three studies from the Middle East testing ACT for individuals experiencing infertility, with promising results.
“To date, there have been only three studies from the Middle East testing the use of ACT for individuals experiencing infertility, with promising results [14–16].”
From Acceptance and commitment therapy adapted for women with infertility: a pilot study of the Infertility ACTion program. (2024) · cites this paper as [14]
Counseling based on ACT improved mental health and quality of life in infertile couples.
“Hosseinpanahi et al. found that counseling based on ACT improved mental health and quality of life in infertile couples [3].”
From The Effects of Acceptance and Commitment Therapy Plus Positive Thinking Training on Distress and Wellbeing in Infertile Women With Marital Conflicts (2021) · cites this paper as [3]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
A-Tjak, J. G. L., Davis, M. L., Morina, N., Powers, M. B., Smits, J. A. J., & Emmelkamp, P. M. G. (2015) · Psychotherapy and Psychosomatics · doi:10.1159/000365764 · Cited by 921 · see citing works
The relationship between stress and infertility
Rooney, K. L., & Domar, A. D. (2018) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2018.20.1/klrooney · Cited by 626 · see citing works
The fertility quality of life (FertiQoL) tool: development and general psychometric properties†
Boivin, J., TAKEFMAN, J. E., & Braverman, A. M. (2011) · Human Reproduction · doi:10.1093/humrep/der171 · Cited by 482 · see citing works
Frederiksen, Y., Farver-Vestergaard, I., Skovgård, N. G., Ingerslev, H. J., & Zachariae, R. (2015) · BMJ Open · doi:10.1136/bmjopen-2014-006592 · Cited by 380 · cited 1× · see citing works
“Reports indicated positive effects of psychological intervention on the rate of fertility and psychological consequences of infertility, such as anxiety, depression, stress, and marital relationship.[28] In a meta‐analytical study (2014), 1821 patients with mental disorders and physical problems have been examined.”
BackgroundLuk, B. H.-K., & Loke, A. Y. (2014) · Journal of Sex & Marital Therapy · doi:10.1080/0092623x.2014.958789 · Cited by 349 · see citing works
Arch, J. J., & Craske, M. G. (2008) · Clinical Psychology: Science and Practice · doi:10.1111/j.1468-2850.2008.00137.x · Cited by 310 · cited 1× · see citing works
“[18] Acceptance and commitment therapy (ACT) is a novel technique for behavioral therapy that employs mindfulness, acceptance, and cognitive diffusion skills to enhance psychological flexibility and prevent behavioral changes in favor of chosen values.[19] Given the high prevalence of infertility and its adverse indiv…”
BackgroundThe Fertility Quality of Life (FertiQoL) tool: development and general psychometric properties
Boivin, J., TAKEFMAN, J. E., & Braverman, A. M. (2011) · Fertility and Sterility · doi:10.1016/j.fertnstert.2011.02.046 · Cited by 213 · see citing works
THE VALIDATION OF GENERAL HEALTH QUESTIONNAIRE- 28 AS A PSYCHIATRIC SCREENING TOOL
Nourbala, A. A., Yazdi, S. A. B., & Kazem, M. (2009) · Hakim Research Journal · Cited by 175 · see citing works
Shindel, A. W., Nelson, C. J., Naughton, C. K., Ohebshalom, M., & Mulhall, J. P. (2008) · The Journal of Urology · doi:10.1016/j.juro.2007.10.069 · Cited by 170 · see citing works
Li, J., Long, L., Liu, Y., He, W., & Li, M. (2015) · Behaviour Research and Therapy · doi:10.1016/j.brat.2015.12.010 · Cited by 109 · see citing works
Using Acceptance and Commitment Therapy to Treat Infertility Stress
Peterson, B. D., & Eifert, G. H. (2011) · Cognitive and Behavioral Practice · doi:10.1016/j.cbpra.2010.03.004 · Cited by 78 · see citing works
The fertility quality of life (FertiQoL) questionnaire in Taiwanese infertile couples
Hsu, P.-Y., Lin, M., Hwang, J., Lee, M., & Wu, M. (2013) · Taiwanese Journal of Obstetrics and Gynecology · doi:10.1016/j.tjog.2013.04.009 · Cited by 75 · see citing works
Epidemiology and Etiology of Infertility in Iran, Systematic Review and Meta-Analysis
Parsanezhad, M. E. (2013) · Journal of Womens Health Issues and Care · doi:10.4172/2325-9795.1000121 · Cited by 52 · see citing works
Abedi Shargh, N., Bakhshani, N. M., Mohebbi, M. D., Mahmudian, K., Ahovan, M., Mokhtari, M., & Gangali, A. (2015) · Global Journal of Health Science · doi:10.5539/gjhs.v8n3p230 · Cited by 38 · see citing works
Sexual Function of Women with Infertility
Salomão, P. B., Navarro, P. A., Romão, A. P. M. S., Lerri, M. R., & Lara, L. A. D. S. (2018) · Revista Brasileira Ginecologia e Obstetrícia · doi:10.1055/s-0038-1673699 · Cited by 37 · see citing works
An overview of the epidemiology of primary infertility in iran.
Kazem, M., & Ardalan, A. (2009) · PubMed · Cited by 30 · see citing works
Evidence-Based Care for Couples With Infertility
Stevenson, E. L., Hershberger, P. E., & Bergh, P. A. (2015) · Journal of Obstetric, Gynecologic & Neonatal Nursing · doi:10.1016/j.jogn.2015.10.006 · Cited by 28 · see citing works
An Overview of the Epidemiology of Primary Infertility in Iran
Mohammad, M., & Kazem (2009) · Cited by 26 · see citing works
Social correlates of female infertility in Uzbekistan.
Jumayev, I., Harun‐Or‐Rashid, M., Rustamov, O., Islamovna, Z. N., Kasuya, H., & Sakamoto, J. (2012) · PubMed Central · doi:10.18999/nagjms.74.3-4.273 · Cited by 19 · see citing works
shafaie, F. S., Mirghafourvand, M., & Rahimi, M. (2014) · International Journal of Women s Health and Reproduction Sciences · doi:10.15296/ijwhr.2014.47 · Cited by 17 · see citing works
Clinical determinants of mental disorders occurring during the infertility treatment.
Holka-Pokorska, J., Jarema, M., & Wichniak, A. (2015) · Psychiatria Polska · doi:10.12740/pp/35958 · Cited by 14 · see citing works
Mirghafourvand, M., Farshbaf‐Khalili, A., & Ghanbari‐Homayi, S. (2018) · Journal of Religion and Health · doi:10.1007/s10943-018-0566-6 · Cited by 13 · see citing works
Kheirkhah, M., Vahedi, M., & Jenani, P. (2014) · Cited by 7 · see citing works
Quality of life and influencing factors among infertile women.
Amanati, L., Mahlagha, A., Shokrabi, S. H., Haghani, H., & Ramazanzadeh, F. (2010) · Cited by 7 · see citing works
Flagged first, then by citations
Research works printed but not linked: 2
- [22]Hashemi F Fili A Safari nia M The effectiveness of stress management (Cognitive Behavior) stress management training on infertile Women's Mental Health Quarterly J Psychol Health 2014 3 55 64
- [26]Hajian Froushani T The Effect of Acceptance and Commitment Therapy (ACT) on Infertility-Related Stress and Adoption in Infertile women Master thesis Ahvaz Jundishapur 2016 University of Medical Sciences
Cited by
Sorted by citations
Dube, L., Bright, K., Hayden, K. A., & Gordon, J. L. (2023) · Human Reproduction Update · doi:10.1093/humupd/dmac034 · Cited by 75 · see citing works
Infertility-related distress and clinical targets for psychotherapy: A qualitative study
Dube, L., Nkosi-Mafutha, N., Balsom, A. A., & Gordon, J. L. (2021) · BMJ Open · doi:10.1136/bmjopen-2021-050373 · Cited by 54 · see citing works
Özdemir, S. Ç., Gangal, A. D., & Erenel, A. Ş. (2024) · Archives of Sexual Behavior · doi:10.1007/s10508-024-02898-2 · Cited by 30 · see citing works
Jackson, P. L., Saunders, P., Mizzi, S., & Hallam, K. T. (2025) · BMC Women s Health · doi:10.1186/s12905-025-04054-x · Cited by 27 · see citing works
Psychological Impact of Infertility. Directions for the Development of Interventions
Vioreanu, A.-M. (2021) · Mental Health Global Challenges Journal · doi:10.32437/mhgcj.v4i1.113 · Cited by 18 · see citing works
The current status of acceptance and commitment therapy (ACT) in Iran: A systematic narrative review
Akbari, M., Seydavi, M., Davis, C. H., Levin, M. E., Twohig, M. P., & Zamani, E. (2022) · Journal of Contextual Behavioral Science · doi:10.1016/j.jcbs.2022.08.007 · Cited by 17 · see citing works
Riddle, J. N., Hopkins, T. A., Yeaton‐Massey, A., & Hellberg, S. N. (2023) · Current Psychiatry Reports · doi:10.1007/s11920-023-01469-x · Cited by 17 · see citing works
Pregnancy and CKD: Advances in Care and the Legacy of Dr Susan Hou
Oliverio, A. L., Bramham, K., & Hladunewich, M. (2021) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2021.07.016 · Cited by 15 · see citing works
Complementary and alternative medicine use in infertility: A review of infertile women's needs
Sharifi, F., & Roudsari, R. L. (2022) · Journal of Education and Health Promotion · doi:10.4103/jehp.jehp_704_21 · Cited by 12 · see citing works
Woodward, J. T., Cirino, N. H., Copland, S. D., & Davoudian, T. (2023) · Clinical Obstetrics & Gynecology · doi:10.1097/grf.0000000000000829 · Cited by 8 · see citing works
Parkinson’s and the couple relationship: a qualitative meta-synthesis
Glover, L., Dixon, C., Kobylecki, C., & Eccles, F. J. R. (2023) · Aging & Mental Health · doi:10.1080/13607863.2023.2227119 · Cited by 8 · see citing works
Schuette, S. A., Andrade, F. C., Woodward, J. T., & Smoski, M. J. (2023) · Journal of Health Psychology · doi:10.1177/13591053231185549 · Cited by 7 · see citing works
“An Iranian study demonstrated positive effects of ACT informed counseling on psychological health and quality of life in infertile couples (Hosseinpanahi et al., 2020).”
BackgroundBalsom, A. A., Klest, B., Sander, B., & Gordon, J. L. (2024) · Reproductive Health · doi:10.1186/s12978-024-01766-5 · Cited by 6 · see citing works
“The interventions ranged from 8 to 20 sessions and were delivered via individual and group therapy formats [14–16].”
BackgroundAcceptance and commitment therapy for couples: A systematic review and meta-analysis
Mairal, J. B., Polanski, T., Duarte‐Díaz, A., & Perestelo‐Pérez, L. (2024) · Journal of Contextual Behavioral Science · doi:10.1016/j.jcbs.2024.100867 · Cited by 5 · see citing works
Kamali, S. K., Sodagar, S., Poursharifi, H., & Hasan, A. (2020) · Journal of Preventive Medicine · doi:10.29252/jpm.7.4.67 · Cited by 5 · see citing works
Psychometric and clinical assessment of the Persian-SCREENIVF among infertile couples
Ghazanfarpour, M., Sorkhani, T. M., Tajadiny, L., Zeynivandnezhad, F., Ahmadi, A., Habibzadeh, V., & Alidousti, K. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e22950 · Cited by 5 · see citing works
Barbosa, C., Santos, S., & Pedro, J. (2024) · Current Psychology · doi:10.1007/s12144-023-05294-6 · Cited by 6 · see citing works
Department of Psychology, F. O. H., Faraji, M., Alimadadi, H., Department of Psychology, F. O. H., Moshfeghi, N., Department of Psychology, F. O. H., Namazi, R., Department of Psychology, F. O. H., Seyed Jafari, J., Department of Psychology, F. O. H., et al. (2021) · Archives of Hygiene Sciences · doi:10.32598/ahs.10.3.215 · Cited by 3 · see citing works
“For example, ACT-based counseling was examined on mental health and quality of life among infertile couples [3].”
BackgroundMethodResultInfluentialSomeia, N. M., Atri, S. B., Areshtanab, H. N., Farshbaf-khalili, A., & Babaie, S. (2024) · BMC Women's Health · doi:10.1186/s12905-024-03442-z · Cited by 2 · see citing works
ŞAHİN, S. B., & Hamarta, E. (2024) · Research on Education and Psychology · doi:10.54535/rep.1557924 · Cited by 3 · see citing works
Zandi, A., Dinpanah-Khoshdarehgi, H., Madahi, M. E., & Jamehri, F. (2023) · Journal of Education and Health Promotion · doi:10.4103/jehp.jehp_1174_22 · Cited by 5 · see citing works
Vakilian, K., Ebrahimi, S., Fouladvand, M., Moslemi, A., & Najdi, N. (2024) · The Open Public Health Journal · doi:10.2174/0118749445267020240209073345 · Cited by 7 · see citing works
Coşkun, M., & Aslan, E. (2025) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2025.114891 · Cited by 1 · see citing works
Wysocka, A. P. (2026) · Psychiatria i Psychologia Kliniczna · doi:10.15557/pipk.2025.0030 · Cited by 1 · see citing works
Moradi, S., Aghaei, A., & Golparvar, M. (2021) · Caspian Journal of Health Research · doi:10.32598/cjhr.6.3.6
Psychological Impact of the COVID-19 Pandemic on Childless Couples
Vasudevan, S. R., & Mohanraj, B. (2023) · Advances in psychology, mental health, and behavioral studies (APMHBS) book series · doi:10.4018/978-1-6684-7221-7.ch007
Noraini, N., Putri, Y. S. E., & Panjaitan, R. U. (2023) · Journal of Telenursing (JOTING) · doi:10.31539/joting.v5i2.7740
Assessment of psychological burden and quality of life in couples undergoing infertility treatments
Munawwer, Priya, K., Rao, D. G., & Mantravadi, K. C. (2025) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-025-03674-4
Balsom, A. A., Klest, B., Sander, B. J., & Gordon, J. L. (2024) · Figshare · doi:10.6084/m9.figshare.26702290
Third wave psychological therapy and infertility: A systematic review
Tavousi, S. A., Rasti-Barzoki, A., khakpour, Z., & Mohammadi, A. H. (2026) · Geopsychiatry · doi:10.1016/j.geopsy.2026.100097
- Authors
- Hosseinpanahi, M., Mirghafourvand, M., Farshbaf-Khalili, A., Esmaeilpour, K., Rezaei, M., & Malakouti, J.
- Affiliations
- Tabriz University of Medical Sciences (IR)
- Kurdistan University of Medical Sciences (IR)
- Corresponding author
- Malakouti, Jamileh
- Venue
- Journal of Education and Health Promotion
- Published
- 2020-01
- Volume
- 9
- Pages
- 251-251
- ISSN
- 2277-9531 (ISSN-L)
- 2319-6440
- PMC
- PMC7657407
- OpenAlex
- W3088905138
- Cited by
- 29
- References
- 24
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 7 · 2023: 9 · 2022: 3 · 2021: 4 · 2020: 1
- FWCI
- 3.75
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Journal of Education and Health Promotion (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-sa)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Social Sciences › Psychology › Social Psychology › Attachment and Relationship Dynamics
- Keywords
- acceptance and commitment therapy, infertility, infertile couples, group counseling, mental health, quality of life, FertiQoL, psychological intervention
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review