How to Interpret LC3 Immunoblotting

Mizushima, Noboru, Yoshimori, Tamotsu·2007·Autophagy

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Items 301–400 of 2,596

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  2. Inhibiting ACAT1/SOAT1 in microglia stimulates autophagy-mediated lysosomal proteolysis and increases Aβ1-42 clearance
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  3. Phospho-ΔNp63α-dependent regulation of autophagic signaling through transcription and micro-RNA modulation
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  4. Dietary methionine availability affects the main factors involved in muscle protein turnover in rainbow trout (Oncorhynchus mykiss)
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    Jianhui Zhu, Aaron M. Gusdon, Hüseyin Çimen, Bennett Van Houten, Emine Koç, Charleen T. Chu · 2012 · Cell Death and Disease
  6. Roles of SIRT1 in the Acute and Restorative Phases following Induction of Inflammation
    Zhiyong Zhang, Stephen F. Lowry, Leonard Guarente, Beatrice Haimovich · 2010 · Journal of Biological Chemistry
  7. Methods for detecting autophagy and determining autophagy-induced cell deathThis review is one of a selection of papers published in a Special Issue on Oxidative Stress in Health and Disease.
    Yongqiang Chen, Meghan B. Azad, Spencer Bruce Gibson · 2010 · Canadian Journal of Physiology and Pharmacology
  8. Endoplasmic reticulum stress induces autophagy in renal proximal tubular cells
    Toshiaki Kawakami, Reiko Inagi, Hideki Takano, Shuzo Sato, Julie R. Ingelfinger, Toshiro Fujita, Masaomi Nangaku · 2009 · Nephrology Dialysis Transplantation
  9. Metabolic effects of fasting on human and mouse blood in vivo
    Federico Pietrocola, Yohann Demont, Francesca Castoldi, David Pierre Enot, Sylvère Durand, Michaëla Semeraro, Elisa Elena Baracco, Jonathan G. Pol, José Manuel Bravo‐San Pedro, Chloé Bordenave et al. · 2017 · Autophagy
  10. Activation of DRD5 (dopamine receptor D5) inhibits tumor growth by autophagic cell death
    Zhi Gen Leng, Shaojian Lin, Ze Rui Wu, Yu Hang Guo, Lin Cai, Han Bing Shang, Hao Tang, Ya Jun Xue, Meiqing Lou, Wenxiu Zhao et al. · 2017 · Autophagy
  11. 20(S)-Ginsenoside Rg3 is a novel inhibitor of autophagy and sensitizes hepatocellular carcinoma to doxorubicin
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  12. Curcumin accelerates the repair of sciatic nerve injury in rats through reducing Schwann cells apoptosis and promoting myelinization
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  13. Diesel exhaust particles induce autophagy and citrullination in Normal Human Bronchial Epithelial cells
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  14. Macrophage LC3-associated phagocytosis is an immune defense against Streptococcus pneumoniae that diminishes with host aging
    Megumi Inomata, Shuying Xu, Pallavi Chandra, Simin Nikbin Meydani, Genzou Takemura, Jennifer A. Philips, John M. Leong · 2020 · Proceedings of the National Academy of Sciences
  15. TNFα modulates protein degradation pathways in rheumatoid arthritis synovial fibroblasts
    A. Connor, N. Mahomed, R. Gandhi, E. Keystone, S. Berger · 2012 · Arthritis Research & Therapy
  16. EGFR-Targeted Hybrid Plasmonic Magnetic Nanoparticles Synergistically Induce Autophagy and Apoptosis in Non-Small Cell Lung Cancer Cells
    Tomohisa Yokoyama, Justina Tam, Shinji Kuroda, Ailing W. Scott, Jesse Aaron, Tim Larson, Manish Shanker, Arlene M. Correa, Seiji Kondo, Jack A. Roth et al. · 2011 · PLoS ONE
  17. Macrolide antibiotics block autophagy flux and sensitize to bortezomib via endoplasmic reticulum stress-mediated CHOP induction in myeloma cells
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  18. Macroautophagy is defective in mucolipin-1-deficient mouse neurons
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  19. A GDI (AGS3) and a GEF (GIV) regulate autophagy by balancing G protein activity and growth factor signals
    Garcia-Marcos, Mikel, Ear, Jason, Farquhar, Marilyn G., Ghosh, Pradipta · 2011 · Molecular Biology of the Cell
  20. Autophagy in Pulmonary Diseases
    Stefan W. Ryter, Kiichi Nakahira, Jeffrey A. Haspel, Augustine M.K. Choi · 2011 · Annual Review of Physiology
  21. HMGB1 downregulation in retinal pigment epithelial cells protects against diabetic retinopathy through the autophagy-lysosome pathway
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  22. Long-term treadmill exercise attenuates tau pathology in P301S tau transgenic mice
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  23. Redox-Active Polymer Microcapsules for the Delivery of a Survivin-Specific siRNA in Prostate Cancer Cells
    Alisa L. Becker, Nicola Ivan Orlotti, Marco Folini · 2011 · ACS Nano
  24. Inhibition of 6-phosphofructo-2-kinase (PFKFB3) induces autophagy as a survival mechanism
    Alden C. Klarer, Julie O’Neal, Yoannis Imbert-Fernandez, Amy L. Clem, Steve R. Ellis, Jennifer A. Clark, Brian F. Clem, Jason Alan Chesney, Sucheta Telang · 2014 · Cancer & Metabolism
  25. Autophagy down regulates pro-inflammatory mediators in BV2 microglial cells and rescues both LPS and alpha-synuclein induced neuronal cell death
    Bussi, Claudio, Peralta Ramos, Javier Maria, Arroyo, Daniela S., Gaviglio, Emilia A., Gallea, Jose Ignacio, Wang, Ji Ming, Celej, Maria Soledad, Iribarren, Pablo · 2017 · Scientific Reports
  26. Dectin-1–Dependent LC3 Recruitment to Phagosomes Enhances Fungicidal Activity in Macrophages
    Tam, Jenny M., Mansour, Michael K., Khan, Nida S., Seward, Michael, Puranam, Sravanthi, Tanne, Antoine, Sokolovska, Anna, Becker, Christine E., Acharya, Mridu, Baird, Michelle A. et al. · 2014 · The Journal of Infectious Diseases
  27. Sustained exposure to the DNA demethylating agent, 2′-deoxy-5-azacytidine, leads to apoptotic cell death in chronic myeloid leukemia by promoting differentiation, senescence, and autophagy
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  28. Sorting cells for basal and induced autophagic flux by quantitative ratiometric flow cytometry
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  29. GLP-1 treatment protects endothelial cells from oxidative stress-induced autophagy and endothelial dysfunction
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  30. Can Antioxidants Protect Against Disuse Muscle Atrophy?
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  31. Oxidative stress-mediated NFκB phosphorylation upregulates p62/SQSTM1 and promotes retinal pigmented epithelial cell survival through increased autophagy
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  36. Anti-proliferative potential of curcumin in androgen-dependent prostate cancer cells occurs through modulation of the Wingless signaling pathway
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  38. The Role of HDAC6 in Autophagy and NLRP3 Inflammasome
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  41. Arsenic induces autophagy in developmental mouse cerebral cortex and hippocampus by inhibiting PI3K/Akt/mTOR signaling pathway: involvement of blood–brain barrier’s tight junction proteins
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  42. Trehalose decreases mutant SOD1 expression and alleviates motor deficiency in early but not end-stage amyotrophic lateral sclerosis in a SOD1-G93A mouse model
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  43. Thyroid Hormone Stimulation of Autophagy Is Essential for Mitochondrial Biogenesis and Activity in Skeletal Muscle
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  44. Glucocorticoid elevation of dexamethasone-induced gene 2 (Dig2/RTP801/REDD1) protein mediates autophagy in lymphocytes
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  45. A novel stroke therapy of pharmacologically induced hypothermia after focal cerebral ischemia in mice
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  47. Androgens Promote Prostate Cancer Cell Growth through Induction of Autophagy
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  48. Coibamide A Induces mTOR-Independent Autophagy and Cell Death in Human Glioblastoma Cells
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  49. PRKCB/protein kinase C, beta and the mitochondrial axis as key regulators of autophagy
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  50. Autophagy in Dictyostelium: Genes and pathways, cell death and infection
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  51. Myc-Driven Overgrowth Requires Unfolded Protein Response-Mediated Induction of Autophagy and Antioxidant Responses in Drosophila melanogaster
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  52. Differently surface-labeled polystyrene nanoplastics at an environmentally relevant concentration induced Crohn’s ileitis-like features via triggering intestinal epithelial cell necroptosis
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  53. The autophagic pathway is a key component in the lysosomal dependent entry ofTrypanosoma cruziinto the host cell
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  54. Mycobacterial Induction of Autophagy Varies by Species and Occurs Independently of Mammalian Target of Rapamycin Inhibition
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  55. Apoptotic and autophagic responses to Bcl-2 inhibition and photodamage
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  56. zVAD-induced autophagic cell death requires c-Src-dependent ERK and JNK activation and reactive oxygen species generation
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  57. Cathepsin Inhibition-Induced Lysosomal Dysfunction Enhances Pancreatic Beta-Cell Apoptosis in High Glucose
    Minjeong Jung, Jaemeun Lee, Hye-Young Seo, Ji Sun Lim, Eun Kyoung Kim · 2015 · PLoS ONE
  58. Autophagy protects LNCaP cells under androgen deprivation conditions
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  59. SH3BP4 Is a Negative Regulator of Amino Acid-Rag GTPase-mTORC1 Signaling
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  60. Preantral follicular atresia occurs mainly through autophagy, while antral follicles degenerate mostly through apoptosis
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  61. Melatonin protects endothelial progenitor cells against AGE-induced apoptosis via autophagy flux stimulation and promotes wound healing in diabetic mice
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  62. Canonical Wnt signaling works downstream of iron overload to prevent ferroptosis from damaging osteoblast differentiation
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  63. The p17 Nonstructural Protein of Avian Reovirus Triggers Autophagy Enhancing Virus Replication via Activation of Phosphatase and Tensin Deleted on Chromosome 10 (PTEN) and AMP-activated Protein Kinase (AMPK), as well as dsRNA-dependent Protein Kinase (PKR)/eIF2α Signaling Pathways
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  64. Anticancer Effects of Bufalin on Human Hepatocellular Carcinoma HepG2 Cells: Roles of Apoptosis and Autophagy
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  65. Autophagy: A New Phase in the Maturation of Growth Plate Chondrocytes Is Regulated by HIF, mTOR and AMP Kinase
    Vickram Srinivas, Jolene Bohensky, Irving M. Shapiro · 2008 · Cells Tissues Organs
  66. Japanese Encephalitis Virus Activates Autophagy as a Viral Immune Evasion Strategy
    Rui Jin, Wandi Zhu, Shengbo Cao, Rui Chen, Hui Min Jin, Yang Liu, Shaobo Wang, Wei Wang, Gengfu Xiao · 2013 · PLoS ONE
  67. Chapter 5 Autophagic Clearance of Aggregate‐Prone Proteins Associated with Neurodegeneration
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  68. Diminished Parkin Solubility and Co-Localization with Intraneuronal Amyloid-β are Associated with Autophagic Defects in Alzheimer's Disease
    Irina Lonskaya, Ashot R. Shekoyan, Michaeline L. Hebron, Nicole M. Desforges, Norah Khaled Algarzae, Charbel Moussa · 2012 · Journal of Alzheimer s Disease
  69. Role of Inositol Trisphosphate Receptors in Autophagy in DT40 Cells
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  70. Short-term calorie restriction protects against renal senescence of aged rats by increasing autophagic activity and reducing oxidative damage
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  71. Herpes Simplex Virus γ34.5 Interferes with Autophagosome Maturation and Antigen Presentation in Dendritic Cells
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  72. P2X7 Receptor Activation Modulates Autophagy in SOD1-G93A Mouse Microglia
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  73. Type I interferons induce autophagy in certain human cancer cell lines
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  74. Endoplasmic Reticulum Protein Quality Control in Neurodegenerative Disease: The Good, the Bad and the Therapy
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  75. Differential responses of blood-brain barrier associated cells to hypoxia and ischemia: a comparative study
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  76. Autophagy is activated by proteasomal inhibition and involved in aggresome clearance in cultured astrocytes
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  77. Rilmenidine promotes MTOR-independent autophagy in the mutant SOD1 mouse model of amyotrophic lateral sclerosis without slowing disease progression
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  78. FOXO are required for intervertebral disk homeostasis during aging and their deficiency promotes disk degeneration
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  79. Sonic hedgehog promotes autophagy of vascular smooth muscle cells
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  80. Inhibiting the ubiquitin–proteasome system leads to preferential accumulation of toxic N-terminal mutant huntingtin fragments
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  83. Disruption of the ribosomal P complex leads to stress-induced autophagy
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  84. Cucurbitacin I Induces Protective Autophagy in Glioblastoma in Vitro and in Vivo
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  85. Modulating lysosomal function through lysosome membrane permeabilization or autophagy suppression restores sensitivity to cisplatin in refractory non-small-cell lung cancer cells
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  86. Ginsenoside Rb1 Enhances Atherosclerotic Plaque Stability by Improving Autophagy and Lipid Metabolism in Macrophage Foam Cells
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  87. Copper accumulation in senescent cells: Interplay between copper transporters and impaired autophagy
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  88. HIV-1 and Morphine Regulation of Autophagy in Microglia: Limited Interactions in the Context of HIV-1 Infection and Opioid Abuse
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  89. Processing of Optineurin in Neuronal Cells
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  90. Metabolic Alterations in Lung Cancer–Associated Fibroblasts Correlated with Increased Glycolytic Metabolism of the Tumor
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  91. Lack of autophagy induces steroid-resistant airway inflammation
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  92. Melatonin modulates autophagy and inflammation protecting human placental trophoblast from hypoxia/reoxygenation
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  94. Regulation of P2X7-dependent inflammatory functions by P2X4 receptor in mouse macrophages
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  97. Autophagic flux determination in vivo and ex vivo
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  98. Autophagy mediates avian influenza H5N1 pseudotyped particle-induced lung inflammation through NF-κB and p38 MAPK signaling pathways
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