The DOI matches its Crossref record; 74 of the 74 references it cites were found in a registry or an index.
Control of cell proliferation pathways by microRNAs
Open accessAbstract
MicroRNAs (miRNAs) are small non-coding RNAs that regulate a large variety of cellular processes including differentiation, apoptosis and proliferation. Several miRNAs display defective expression patterns in human tumors with the consequent alteration of target oncogene or tumor suppressor genes. Many of these miRNAs modulate the major proliferation pathways through direct interaction with critical regulators such as RAS, PI3K/PTEN or ABL, as well as members of the retinoblastoma pathway, Cyclin-CDK complexes or cell cycle inhibitors of the INK4 or Cip/Kip families. A complex interplay between miRNAs and MYC or E2F family members also exists to modulate cell cycle-dependent transcription during normal or tumoral proliferation. The ability of miRNAs to modulate these proliferation pathways may have relevant implications not only in physiological or developmental processes but also in tumor progression or cancer therapy.
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Cites
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Cited by
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MicroRNAs: Novel regulators in the hallmarks of human cancer
Ruan, K., Fang, X., & Ouyang, G. (2009) · Cancer Letters · doi:10.1016/j.canlet.2009.04.031 · Cited by 447
The role of microRNAs in endometriosis and associated reproductive conditions
Ohlsson Teague, E. M. C., Print, C. G., & Hull, M. L. (2010) · Human Reproduction Update · doi:10.1093/humupd/dmp034 · Cited by 309
Kuokkanen, S., Chen, B., Ojalvo, L., Benard, L., Santoro, N., & Pollard, J. W. (2010) · Biology of Reproduction · doi:10.1095/biolreprod.109.081059 · Cited by 288
Tömböl, Z., Szabó, P. M., Molnár, V., Wiener, Z., Tölgyesi, G., Horányi, J., Riesz, P., Reismann, P., Patócs, A., Likó, I., et al. (2009) · Endocrine Related Cancer · doi:10.1677/erc-09-0096 · Cited by 176
Metadata
- Authors
- Bueno, M. J., de Castro, I. P., & Malumbres, M.
- Venue
- Cell Cycle
- Publisher
- Informa UK Limited
- Published
- 2008-10-15
- Volume
- 7
- Issue
- 20
- Pages
- 3143-3148
- ISSN
- 1538-4101 (ISSN-L)
- 1551-4005
- OpenAlex
- W1979413046
- Cited by
- 345
- References
- 74
- FWCI
- 6.27
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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