The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Role of commensal gut bacteria in inflammatory bowel diseases
Open accessAbstract
Aberrant immune responses toward commensal gut bacteria can result in the onset and perpetuation of inflammatory bowel diseases (IBD). Reduced microbiota diversity in conjunction with lower proportion of Gram positive and higher proportion of Gram negative bacteria than in healthy subjects is frequently reported in IBD patients. In a subset of IBD patients, E. coli strains with specific features trigger disease. Important molecular mechanisms underlying this effect have been identified. However, in the majority of patients the exact nature of host-microbe interactions that contribute to IBD development has so far not been defined. The application of metagenomic techniques may help to identify bacterial functions that are involved in the aggravation or alleviation of IBD. Subsequently, the relevance for disease development of bacterial candidate genes may be tested taking advantage of reductionist animal models of chronic gut inflammation. This approach may help to identify bacterial functions that can be targeted in future concepts of IBD therapy.
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Cites
Reduced diversity of faecal microbiota in Crohn’s disease revealed by a metagenomic approach
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Dysbiosis of the faecal microbiota in patients with Crohn’s disease and their unaffected relatives
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Depletion of luminal iron alters the gut microbiota and prevents Crohn's disease-like ileitis
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Cited by
The role of the microbiota in periodontal disease
Curtis, M. A., Diaz, P. I., & Van Dyke, T. E. (2020) · Periodontology 2000 · doi:10.1111/prd.12296 · Cited by 698
Audebert, C., Even, G., Cian, A., The Blastocystis Investigation Group, Safadi, D. E., Certad, G., Delhaes, L., Pereira, B., Nourrisson, C., Poirier, P., et al. (2016) · Scientific Reports · doi:10.1038/srep25255 · Cited by 284
Using Corticosteroids to Reshape the Gut Microbiome: Implications for Inflammatory Bowel Diseases
Huang, E. Y., Inoue, T., Leone, V. A., Dalal, S., Touw, K., Wang, Y., Musch, M. W., Theriault, B., Higuchi, K., Donovan, S., et al. (2015) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000332 · Cited by 204
Ahuja, M., Schwartz, D. M., Tandon, M., Son, A., Zeng, M., Swaim, W., Eckhaus, M., Hoffman, V., Cui, Y., Xiao, B., et al. (2017) · Cell Metabolism · doi:10.1016/j.cmet.2017.02.007 · Cited by 195
Involvement of the gut microbiota and barrier function in glucocorticoid-induced osteoporosis
Schepper, J. D., Collins, F., Rios-Arce, N. D., Kang, H. J., Schaefer, L., Gardinier, J. D., Raghuvanshi, R., Quinn, R. A., Britton, R., Parameswaran, N., et al. (2020) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.3947 · Cited by 199
Metadata
- Authors
- Loh, G., & Blaut, M.
- Venue
- Gut Microbes
- Publisher
- Informa UK Limited
- Published
- 2012-11-16
- Volume
- 3
- Issue
- 6
- Pages
- 544-555
- ISSN
- 1949-0976 (ISSN-L)
- 1949-0984
- OpenAlex
- W2000844307
- Cited by
- 177
- References
- 11
- FWCI
- 3.25
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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