The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
The alphabet of intrinsic disorder: I. Act like a Pro: On the abundance and roles of proline residues in intrinsically disordered proteins
Open accessAbstract
A significant fraction of every proteome is occupied by biologically active proteins that do not form unique three-dimensional structures. These intrinsically disordered proteins (IDPs) and IDP regions (IDPRs) have essential biological functions and are characterized by extensive structural plasticity. Such structural and functional behavior is encoded in the amino acid sequences of IDPs/IDPRs, which are enriched in disorder-promoting residues and depleted in order-promoting residues. In fact, amino acid residues can be arranged according to their disorder-promoting tendency to form an alphabet of intrinsic disorder that defines the structural complexity and diversity of IDPs/IDPRs. This review is the first in a series of publications dedicated to the roles that different amino acid residues play in defining the phenomenon of protein intrinsic disorder. We start with proline because data suggests that of the 20 common amino acid residues, this one is the most disorder-promoting.
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Self-citationSerine/threonine phosphatases: mechanism through structure
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Influence of proline residues on protein conformation
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Intrinsically disordered proteins and multicellular organisms
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Self-citationCasein and casein micelle structures, functions and diversity in 20 species.
Holt, C. (2016) · International Dairy Journal · doi:10.1016/j.idairyj.2016.01.004 · Cited by 95
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Metadata
- Authors
- Theillet, F.-X., Kalmar, L., Tompa, P., Han, K.-H., Selenko, P., Dunker, A. K., Daughdrill, G. W., & Uversky, V. N.
- Venue
- Intrinsically Disordered Proteins
- Publisher
- Informa UK Limited
- Published
- 2013-01
- Volume
- 1
- Issue
- 1
- Pages
- e24360
- ISSN
- 2169-0693 (ISSN-L)
- 2169-0707
- OpenAlex
- W1501347866
- Cited by
- 286
- References
- 11
- FWCI
- 5.24
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Theillet, F.-X., Kalmar, L., Tompa, P., Han, K.-H., Selenko, P., Dunker, A. K., Daughdrill, G. W., & Uversky, V. N. (2013). The alphabet of intrinsic disorder: I. Act like a Pro: On the abundance and roles of proline residues in intrinsically disordered proteins. Intrinsically Disordered Proteins. https://doi.org/10.4161/idp.24360
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