The DOI matches its Crossref record; 98 of the 98 references it cites were found in a registry or an index.
The role of JAK-STAT signaling within the CNS
Open accessAbstract
JAK-STAT is an efficient and highly regulated system mainly dedicated to the regulation of gene expression. Primarily identified as functioning in hematopoietic cells, its role has been found critical in all cell types, including neurons. This review will focus on JAK-STAT functions in the mature central nervous system. Our recent research suggests the intriguing possibility of a non-nuclear role of STAT3 during synaptic plasticity. Dysregulation of the JAK-STAT pathway in inflammation, cancer and neurodegenerative diseases positions it at the heart of most brain disorders, highlighting the importance to understand how it can influence the fate and functions of brain cells.
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STAT3 is a Critical Regulator of Astrogliosis and Scar Formation after Spinal Cord Injury
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Metadata
- Authors
- Nicolas, C. S., Amici, M., Bortolotto, Z. A., Doherty, A., Csaba, Z., Fafouri, A., Dournaud, P., Gressens, P., Collingridge, G. L., & Peineau, S.
- Venue
- JAK-STAT
- Publisher
- Informa UK Limited
- Published
- 2013-01
- Volume
- 2
- Issue
- 1
- Pages
- e22925
- ISSN
- 2162-3988 (ISSN-L)
- 2162-3996
- OpenAlex
- W2052593121
- Cited by
- 351
- References
- 98
- FWCI
- 9.33
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Nicolas, C. S., Amici, M., Bortolotto, Z. A., Doherty, A., Csaba, Z., Fafouri, A., Dournaud, P., Gressens, P., Collingridge, G. L., & Peineau, S. (2013). The role of JAK-STAT signaling within the CNS. JAK-STAT. https://doi.org/10.4161/jkst.22925
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