The DOI matches its Crossref record; 88 of the 88 references it cites were found in a registry or an index.
VEGF in the nervous system
Open accessAbstract
Vascular endothelial growth factor (VEGF, VEGFA) is critical for blood vessel growth in the developing and adult nervous system of vertebrates. Several recent studies demonstrate that VEGF also promotes neurogenesis, neuronal patterning, neuroprotection and glial growth. For example, VEGF treatment of cultured neurons enhances survival and neurite growth independently of blood vessels. Moreover, evidence is emerging that VEGF guides neuronal migration in the embryonic brain and supports axonal and arterial co-patterning in the developing skin. Even though further work is needed to understand the various roles of VEGF in the nervous system and to distinguish direct neuronal effects from indirect, vessel-mediated effects, VEGF can be considered a promising tool to promote neuronal health and nerve repair.
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Cites
The biology of VEGF and its receptors
Ferrara, N., Gerber, H.-P., & LeCouter, J. (2003) · Nature Medicine · doi:10.1038/nm0603-669 · Cited by 9,591
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
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Risau, W. (1997) · Nature · doi:10.1038/386671a0 · Cited by 5,727
The Biology of Vascular Endothelial Growth Factor
Ferrara, N., & Davis-Smyth, T. (1997) · Endocrine Reviews · doi:10.1210/edrv.18.1.0287 · Cited by 4,330
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
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Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
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Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
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VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia
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Self-citationRole of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
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Yuen, T. J., Silbereis, J. C., Griveau, A., Chang, S. M., Daneman, R., Fancy, S. P. J., Zahed, H., Maltepe, E., & Rowitch, D. H. (2014) · Cell · doi:10.1016/j.cell.2014.04.052 · Cited by 433
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Duman, R. S., Deyama, S., & Fogaça, M. V. (2021) · European Journal of Neuroscience · doi:10.1111/ejn.14630 · Cited by 321
The neurovascular link in health and disease: molecular mechanisms and therapeutic implications
Quaegebeur, A., Lange, C., & Carmeliet, P. (2011) · Neuron · doi:10.1016/j.neuron.2011.07.013 · Cited by 247
VEGF ligands and receptors: implications in neurodevelopment and neurodegeneration
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Metadata
- Authors
- Rosenstein, J. M., Krum, J. M., & Ruhrberg, C.
- Venue
- Organogenesis
- Publisher
- Informa UK Limited
- Published
- 2010-04
- Volume
- 6
- Issue
- 2
- Pages
- 107-114
- ISSN
- 1547-6278 (ISSN-L)
- 1555-8592
- OpenAlex
- W2085292494
- Cited by
- 314
- References
- 88
- FWCI
- 3.78
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Rosenstein, J. M., Krum, J. M., & Ruhrberg, C. (2010). VEGF in the nervous system. Organogenesis. https://doi.org/10.4161/org.6.2.11687
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
