Ras history: The saga continues

Cox, Adrienne D., Der, Channing J.·2010·Small GTPases

Cited by (712)

Items 601–700 of 712

  1. An Introduction to Signal Transduction
    IJsbrand M. Kramer · 2015 · Elsevier eBooks
  2. Molecular Pathology of Cancer
    Gabriel D. Dakubo · 2016 · Springer eBooks
  3. GTP-Competitive Inhibitors of RAS Family Members
    J.C. Hunter, Nathanael S. Gray, Kenneth D. Westover · 2016 · Elsevier eBooks
  4. A Comprehensive Evaluation of Solid Tumor Analysis in the Clinical Space
    Kevin Kelly, Aleksandra Ras, Samantha Helm · 2016 · Journal of Next Generation Sequencing & Applications
  5. Molecular Aspects of Thyroid Carcinogenesis
    Rita Seeböck, Johannes Haybaeck, Oleksiy Tsybrovskyy · 2017 · Springer eBooks
  6. Targeting der kleinen GTPasen über ihre regulatorischen Proteine
    Janine L. Gray, F. von Delft, Paul E. Brennan · 2019 · Angewandte Chemie
  7. KRas4BG12C/D/PDE6δ Heterodimeric Molecular Complex: A Target Molecular Multicomplex for the Identification and Evaluation of Nontoxic Pharmacological Compounds for the Treatment of Pancreatic Cancer
    Paola Briseño-Díaz, Dora Emma Vélez-Uriza, Pedro Cruz-Nova, Martiniano Bello, José Correa‐Basurto, Rosaura Hernández‐Rivas, Ma del Rocio Thompson Bonilla, Miguel Angel Vargas · 2020 · IntechOpen eBooks
  8. Functional Annotation of Genes of Predisposition to Schizophrenia and Celiac Disease
    N. Yu. Chasovskikh, A. Yu. Grechishnikova · 2020 · Russian Journal of Genetics
  9. Kras Mutations and Egfr Expression as Prognostic and Predictive Factors in Cancer Patients
    2023 · Journal of Population Therapeutics and Clinical Pharmacology
  10. Biochemical Pathways in Cancer
    Eun-Kyoung Yim Breuer, Mandi M. Murph, Rolf J. Craven · 2012 · Biochemistry Research International
  11. Targeting the Ras-Ral effector pathway for cancer treatment
    Leanna R. Gentry · 2019 · Carolina Digital Repository (University of North Carolina at Chapel Hill)
  12. Integration of Multi-level Molecular Scoring for the Interpretation of RAS-Family Genetic Variation
    Swarnendu Tripathi, Nikita R. Dsouza, Raul A. Urrutia, Michael T. Zimmermann · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  13. Investigation of the anti-cancer effects of rosemary (Rosmarinus Officinalis L.) extract in human breast and prostate cancer cells
    Alina Jaglanian · 2019 · Brock University Digital Repository (Brock University)
  14. Investigation of KRAS Dependency Bypass and Functional Characterization of All Possible KRAS Missense Variants
    Seav Huong Ly · 2018 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)
  15. Evolution of structural dynamics in bilobed proteins
    Giorgos Gouridis, Yusran Abdillah Muthahari, Marijn de Boer, Konstantinos Tassis, Alexandra Tsirigotaki, Niels Zijlstra, Nikolaos Eleftheriadis, Ruixue Xu, Martin Zacharias, Douglas A. Griffith et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  16. Small GTPases
    Kate H. Pedone, Channing J. Der · 2013 · Encyclopedia of Biological Chemistry
  17. p120RasGAP
    Channing J. Der, J.L. Sells · 2013 · Elsevier eBooks
  18. CRISPR prime editing for unconstrained correction of oncogenic KRAS variants
    Gayoung Jang, Jiyeon Kweon, Yongsub Kim · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  19. A Perspective on Covalent Inhibitors: Research and Development Trends of Warheads and Targets
    Haitao Chen, Robert E. Bird, Da-Sheng Wang, Leilani M. Lotti Diaz, Kavita A. Iyer, Krittika Ralhan, Gary R. Gustafson, Junko Kato-Weinstein, Qiongqiong Angela Zhou · 2023 · ChemRxiv
  20. Development of Dual-Pathway Inhibitors of Raf/MEK/ERK and PI3K/Akt Signaling Pathways.
    Sasha Fraser · 2011 · VCU Scholars Compass (Virginia Commonwealth University)
  21. Rabs and Other G Proteins
    G. Li · 2015 · Elsevier eBooks
  22. RAS Genes and Cancer
    Tikvah K. Hayes, Jeran K. Stratford, Andrea Wang‐Gillam, Channing J. Der · 2014 · Springer eBooks
  23. Ras
    Adrienne D. Cox, Molly J. DeCristo · 2013 · Cambridge University Press eBooks
  24. Mechanisms of KRAS-Mediated Pancreatic Tumor Formation and Progression: A Dissertation
    Victoria A. Appleman · 2012 · The Journal of the American Medical Association (JAMA) Network (American Medical Association)
  25. Coordinate regulation of the WNT and Hippo pathways by the novel Ras effector NORE1A.
    Marvin Schmidt · 2015
  26. Structural Analysis of Active Site Conformations in Ras and Rap1 GTPases.
    Genevieve Anne Holzapfel · 2011 · NCSU Libraries Repository (North Carolina State University Libraries)
  27. Modeling GTP hydrolysis in RasGAP protein complex
    Maria G. Khrenova, Ekaterina D. Kots, Anna M. Kulakova, Igor V. Polyakov · 2016 · Moscow University Chemistry Bulletin
  28. Regulation of the retinoblastoma tumor suppressor by the novel Ras effector NORE1A.
    Thibaut Barnoud · 2015
  29. A link between endosomal trafficking and signaling
    Rajesh Ghai, Brett M. Collins · 2011
  30. Synthetic lethality and chemoresistance in cancer
    Kimberly Maxfield, Angelique W. Whitehurst · 2015 · Cambridge University Press eBooks
  31. Quantitative Super-Resolution Microscopy for Cancer Biology and Medicine
    2016 · Series in cellular and clinical imaging
  32. Molecular Genetics of Pheochromocytoma and Paraganglioma
    Mercedes Robledo, María Currás-Freixes, Alberto Cascón · 2016 · Springer eBooks
  33. Beyond Reductionism and Emergence: A Study of the Epistemic Practices in Gene Expression Research
    Valérie Racine · 2016
  34. Study of signal transduction in reconstituted membranes: Ras activation by SOS and RasGRP1
    Hsiung‐Lin Tu · 2013 · eScholarship (California Digital Library)
  35. Exploration of the role of CIB1 in cell survival and tumor growth
    Justin L. Black · 2019 · Carolina Digital Repository (University of North Carolina at Chapel Hill)
  36. Regulation of the kRAS Promoter in Pancreatic Cancer by Proteins and Small Molecules
    Harshul Batra · 2017 · ProQuest Demo Repository
  37. TARGETING THE ERK MAPK PATHWAY IN RAS-DRIVEN CANCERS
    Meagan B. Ryan · 2019 · Carolina Digital Repository (University of North Carolina at Chapel Hill)
  38. Evaluating the therapeutic potential of the PAK1 and TBK1 kinases in pancreatic ductal adenocarcinoma
    Nicole M. Baker · 2019 · Carolina Digital Repository (University of North Carolina at Chapel Hill)
  39. Selective targeting of an oncogenic KRAS mutant allele by CRISPR/Cas9 induces efficient tumor regression
    Qianqian Gao, Wenjie Ouyang, Bin Kang, Xu Han, Ying Xiong, Renpeng Ding, Yijian Li, Fei Wang, Lei Huang, Lei Chen et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  40. Regulation of dendritic morphology and synapse formation by the intellectual disability associated palmitoyl acyl transferases zDHHC15 and zDHHC9
    Jordan J. Shimell · 2019 · cIRcle (University of British Columbia)
  41. Rala and the exocyst control Pvr trafficking and signaling to ensure lymph gland homeostasis in Drosophila melanogaster
    Helene Knævelsrud, Caroline Baril, Gwenaëlle Gavory, Jorrit M. Enserink, Marc Therrien · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  42. Survival Outcomes of Metastatic Colorectal Cancer Patients in Brunei Darussalam and the Impact of KRAS Mutations
    Datul Damit, Ravi Sekhar Patnaik, Liling Chaw, Shir Kiong Lu, Telisinghe Pemasiri Upali, Zen Huat Lu, Kenneth Yuh Yen Kok, Ya Chee Lim · 2020 · Preprints.org
  43. Mapping the Radiogenome of Human Cancers
    Priyanka Gopal, Jessica A. Castrillon, Mohamed E. Abazeed · 2020 · Cancer drug discovery and develogment/Cancer drug discovery and development
  44. Metabolic effects of oncogenic K-Ras in cancer cells
    Richmond Bergner · 2018
  45. Fostering a concept: Why cell identity matters
    Mihail Eugen Hinescu · 2020 · Journal of Cell Identity
  46. Anaplastic lymphoma kinase activity, a therapeutic target, suppresses neuroblastoma cell differentiation
    Joachim T. Siaw · 2020 · Gothenburg University Publications Electronic Archive (Gothenburg University)
  47. Ras and Ras Signaling as a Therapeutic Target in Cancer
    Bailee H. Sliker, Paul M. Campbell · 2021 · Elsevier eBooks
  48. The Role of Structural Dynamics in Protein Function and Evolvability
    Yusran Abdillah Muthahari · 2021
  49. INTERACTOME REWIRING THROUGH CANCER-ASSOCIATED MUTATION IN GROWTH FACTOR SIGNALING PATHWAYS
    Cassandra-Jin Wong · 2017 · TSpace (University of Toronto)
  50. Ras, TrkB, and ShcA Protein Expression Patterns in Pediatric Brain Tumors
    Monika Prill, Agnieszka Karkucińska‐Więckowska, Magdalena Lebiedzińska, Giampaolo Morciano, Agata Charzyńska, Michał Dąbrowski, Maciej Pronicki, Paolo Pinton, Wiesława Grajkowska, Mariusz Roman Wieckowski · 2021 · Journal of Clinical Medicine
  51. Review on Colonrectal Cancer
    Xinghan Huang · 2021 · E3S Web of Conferences
  52. Mechanistic Insight on Ras Inhibition Strategies in Cancer Therapy
    Jeiran Pashapour Anoosheh, Abolfazl Barzegar, Mohammad Saeid Hejazi, Nikoo Hasheminejad, Hamid Reza Heidari, Elnaz Mehdizadeh Aghdam · 2021 · Pharmaceutical Sciences
  53. Chemical Approach Toward Controlling of Transient Protein Interactions
    Junko Ohkanda · 2021 · Springer eBooks
  54. Structural depiction and analysis of RasGap protein using molecular dynamics simulations
    Virupaksha Ajit Bastikar, Gupta Pramodkumar P., Kumar Piyush, Alpana Bastikar, Chhajed Santosh S. · 2021 · Journal of Applied Pharmaceutical Science
  55. Brain I3 Binding Protein regulates K-Ras4B membrane localization and signaling
    Ian P. McCabe, Huanqing Zhang, Jonathan A. Cooper, David L. Turner, Anne B. Vojtek · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  56. Different Oncogenic KRAS Mutations Produce Distinct Heterogeneous Outcomes In Signaling Pathways Of Isogenic Mouse Embryonic Fibroblasts
    Emna El Gazzah · 2021
  57. Mutant K-Ras Mediated Oxidative Stress in Pancreatic Cancer
    Divya Thomas, Satish Sagar, Tristan Caffrey, Prakash Radhakrishnan · 2021 · Springer eBooks
  58. Investigating ALK inhibitors alone or in combination as therapeutic options for ALK-positive neuroblastoma
    Muhammad Wasi Alam · 2021 · Gothenburg University Publications Electronic Archive (Gothenburg University)
  59. Photodynamic therapy targeting nucleic acid G-quadruplexes
    Takeru Torii, Natsuki Kinoshita, Ryoto Urano, Daisuke Miyoshi, Keiko Kawauchi · 2022 · Journal of The Society of Japanese Women Scientists
  60. Megaviruses contain various genes encoding for eukaryotic vesicle trafficking factors
    Émilie Neveu, Dany Khalifeh, Dirk Fasshauer · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  61. Rab GTPases and Other G Proteins
    Guangpu Li, Matthew Caleb Marlin · 2022 · Elsevier eBooks
  62. G-proteins | Small GTPases
    Kate H. Pedone, Channing J. Der, Vivian Kitainda · 2021 · Elsevier eBooks
  63. Peer Review #2 of "Prognostic value of KRAS mutation status in colorectal cancer patients: a population-based competing risk analysis (v0.1)"
    2020 · PeerJ
  64. Peer Review #1 of "Prognostic value of KRAS mutation status in colorectal cancer patients: a population-based competing risk analysis (v0.1)"
    2020 · PeerJ
  65. Ras Proteins☆
    Stanley George, C. J. Der · 2016 · Elsevier eBooks
  66. G-proteins | Ras Family
    Lawrence A. Quilliam · 2020 · Elsevier eBooks
  67. Peer Review #2 of "Prognostic value of KRAS mutation status in colorectal cancer patients: a population-based competing risk analysis (v0.2)"
    2020 · PeerJ
  68. Targeting a broad spectrum of KRAS -mutant cancers by hyperactivation-induced cell death
    Johanna Lilja, Jasmin Kaivola, James R. W. Conway, Joni Vuorio, Hanna Parkkola, Pekka Roivas, Taru Varila, Guillaume Jacquemet, Emilia Peuhu, Emily Wang et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  69. KRAS G12C mutation: from black sheep to key player in pancreatic cancer treatment
    Rebecca Ibrahim, Rita Khoury, Tony Ibrahim, Tarek Assi, Axel Le Cesne · 2023 · Future Oncology
  70. Regulation of alternative polyadenylation isoforms of Timp2 is an effector event of RAS signaling in cell transformation
    Yuxi Ai, Qingbao Ding, Zezhong Wan, Sanjay Tyagi, Alexandra Indeglia, Maureen E. Murphy, Bin Tian · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  71. Conclusions: the future of RAS drug discovery
    Adrian L. Gill, Kevan M. Shokat · 2024 · Elsevier eBooks
  72. Drug(gable) Targets Discovery
    Yizhi Li, Siqi Xiang · 2024 · Springer eBooks
  73. Impact of Mutational Status on Intracellular Effects of Cell‐Permeable CaaX Peptides in Pancreatic Cancer Cells
    Merlin Klußmann, Martin Matijass, Ines Neundorf · 2025 · ChemBioChem
  74. Clonal effects of the Ras oncogene revealed by somatic mutagenesis in a Drosophila cancer model
    Takuya Akiyama, Matthew C. Gibson · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  75. RAS oncogenes in Venezuelan colorectal cancer: detection methods and mutational profile review
    Carlos Darío Ramírez, Daniela Rodríguez-Carrascal, Rafael Puche · 2025 · Academia oncology.
  76. DA-Raf synergistically binds to the plasma membrane and Ras to suppress ERK signaling
    Kazunori Takano, Kazuya Tsujita, Akiko Suganami, Takuhiko Nakamura, Emiri Kanno, Yutaka Tamura, Toshiki Itoh, Takeshi Endo · 2025 · Life Science Alliance
  77. Ubiquitin-independent pathway regulates the RIT1-MAPK pathway in chordoma progression
    Hui Chen, Qiujing Guan, Cheng Yang, Yang Chen, Yan Liu, Wenjie Ren, Su Chen, Lei Li, Dongxia Li, Jianguo Tang et al. · 2025 · Cell Death and Disease
  78. Dissecting Mechanisms of Ligand Binding and Conformational Changes in the Glutamine-Binding Protein
    Zhongying Han, Sabrina Panhans, Sophie Brameyer, Ecenaz Bilgen, Marija Ram, Anna Herr, Alessandra Narducci, Michael Isselstein, Paul David Harris, Oliver Brix et al. · 2025 · eLife
  79. Comparative analysis of interactions of the RASSF family mediated by the Ras-association (RA) and SARAH domains
    JJ Chan · 2013 · UCL Discovery (University College London)
  80. Additional file 1 of Identification and biochemical characterisation of Acanthamoeba castellanii cysteine protease 3
    Wang, Zhixin, Duo Wu, Tachibana, Hiroshi, Meng Feng, Cheng, Xun-jia · 2020 · Figshare
  81. Additional file 1 of Clinical significance of HRAS and KRAS genes expression in patients with non–small-cell lung cancer - preliminary findings
    Milena Pązik, Katarzyna Michalska, Marta Żebrowska-Nawrocka, Izabela Zawadzka, Mariusz Piotr Łochowski, Ewa Izabela Balcerczak · 2021 · Figshare
  82. Additional file 1 of Molecular profile of KRAS G12C-mutant colorectal and non-small-cell lung cancer
    Araujo, Luiz Henrique, Bianca Mendes Souza, Laura Rabelo Leite, Parma, Sabrina A. F., Natália Penido Lopes, Malta, Frederico S. V., Maíra Cristina Menezes Freire · 2021 · Figshare
  83. KRASAVA—An Expert System for Virtual Screening of KRAS G12D Inhibitors
    Oleg V. Tinkov, Pavel E. Gurevich, Sergei A. Nikolenko, Shamil D. Kadyrov, Natalya S. Bogatyreva, Veniamin Y. Grigorev, Dmitry N. Ivankov, Marina A. Pak · 2025 · International Journal of Molecular Sciences
  84. Discovery of potent KRASG12D inhibitors disrupting RAS-Raf interaction to block activation
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  85. Conventional and Novel Approaches to Establishing Mouse Models of Gastric Cancer in the Past, Present, and Potential Post-H. Pylori Infection Era
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  86. Determining the Role of KRAS in Patients with Different Demographic Profiles Diagnosed with Diabetes Mellitus: A Case-Control Study
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  87. Ras G12V Oncogene-Induced Epithelial Senescence and Its Relay Promotes Host Metabolic Syndrome in Drosophila
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  88. Etude et modulation des interactions protéine-protéine : l’activation de la petite protéine G Arf1 par son facteur d’échange Arno
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  89. Signatures moléculaires impliquées dans la transformation des cellules Bhas 42 induite par les silices amorphes synthétiques
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  90. Évaluation du patrimoine tumoral circulant dans la prise en charge thérapeutique des patients atteints de cancer broncho-pulmonaire
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  91. In silico screening of NRas protein oncogenic mutations : new structural and physico-chemical insights into the catalytic activity
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  93. A yeast-based assay to screen protein-protein interaction modulators
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  94. Innovative targeted therapies for mosaic RAS-related vascular malformations
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  95. Régulation de l'assemblage des complexes d'adhésion focale au cours de la motilité aventurière de Myxococcus xanthus
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  96. Apport de l'ADN circulant tumoral dans les cancers digestifs
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  97. High-throughput screening identifies NT-1 that synergizes with MRTX1133 against acquired resistant KRASG12D colorectal cancer
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  98. Regulation of Rho1 by RhoGAPs during drosophila germ band extension
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  99. Constitutively active RAS prolongs Cdc42 signalling, while MAPK signalling is attenuated during fission yeast mating
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