Lactic dehydrogenase in umbilical cord blood in healthy infants after different modes of delivery

“This is well known from studies of non-pregnant women and the explanation given is that cigarette smoke contains oxidative compounds which destabilise the erythrocyte membrane [17,18].”

“3 g/L (maximal increase 17 ± 2%) [16] for the present results would be a small overestimation of the LDH median and percentile values.”

“An increased sensitivity to peroxidation and different lipid composition of the erythrocyte membrane has been described in obese women [19], but we have not found evidence in the literature to indicate whether this also holds for their fetuses and infants.”

“6 g/L did increase LDH by 34 per cent compared to samples without haemolysis [15].”

“Lactate Dehydrogenase (LDH) increases early in newborns in several critical conditions, and the LDH activity correlates well with the severity of diseases such as asphyxia [1-4] respiratory distress and Necrotizing Enterocolitis (NEC).”

“The two most common reasons for acute operative intervention (abdominal or vaginal) were labor dystocia in 43% (41/95) and non-reassuring cardiotocographic (CTG) patterns [6-9] in 37% (35/95).”

“We included infants born after caesarean section and vacuum extraction but also analyzed them separately based on previous research showing increased LDH in infants with fetal distress and asphyxia [10-12].”

“In spite of the increased values seen after instrumental/operative delivery in this study, the levels of LDH are low compared to values seen in newborns subjected to severe asphyxia [3,20].”

“Lactate Dehydrogenase (LDH) increases early in newborns in several critical conditions, and the LDH activity correlates well with the severity of diseases such as asphyxia [1-4] respiratory distress and Necrotizing Enterocolitis (NEC).”

“The two most common reasons for acute operative intervention (abdominal or vaginal) were labor dystocia in 43% (41/95) and non-reassuring cardiotocographic (CTG) patterns [6-9] in 37% (35/95).”

“The major reason for excluding samples in the present study was invitro haemolysis, a common finding in samples from children, especially newborns [13,14].”

“The major reason for excluding samples in the present study was invitro haemolysis, a common finding in samples from children, especially newborns [13,14].”

“2 ukat/L) cut-off seems to be clinically useful also in other conditions that cause illness in the neonatal period [21-23].”

“The two most common reasons for acute operative intervention (abdominal or vaginal) were labor dystocia in 43% (41/95) and non-reassuring cardiotocographic (CTG) patterns [6-9] in 37% (35/95).”

“2 ukat/L) cut-off seems to be clinically useful also in other conditions that cause illness in the neonatal period [21-23].”

“Lactate Dehydrogenase (LDH) increases early in newborns in several critical conditions, and the LDH activity correlates well with the severity of diseases such as asphyxia [1-4] respiratory distress and Necrotizing Enterocolitis (NEC).”

“2 ukat/L) cut-off seems to be clinically useful also in other conditions that cause illness in the neonatal period [21-23].”

“Cord blood is easily accessible immediately after birth, but reference values have only been reported for a limited number of healthy infants in which the means of excluding factors that might affect LDH in plasma are not described [3-5].”

“They also concluded that neonates delivered by elective LSCS had significantly lower cord blood LDH levels [22].”

“Maternal hypotension caused by regional anesthesia may affect uteroplacental blood flow, resulting in fetal acidosis, asphyxia, and low Apgar scores (12,13).”