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Inhibition of Amino Acid Decarboxylase Activity of Enterobacter aerogenes by Active Components in Spices
Open accessAbstract
The water and ethanol extracts of several commercially available spices were examined for their inhibitory action on the decarboxylase activity of a crude extract of Enterobacter aerogenes . The water extracts had a negligible effect on histidine decarboxylase activity, except for water extract of cloves which reduced the activity by about 40%. However, the ethanol extracts had a rather higher inhibitory action upon histidine, lysine, and ornithine decarboxylases. Of the spices used, cloves, cinnamon, sage, nutmeg, and allspice were very effective in inhibiting the decarboxylases. Among the components of those spices, cinnamaldehyde and eugenol were found to be effective inhibitors.
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In the citing paper
“Cinnamaldehyde is indeed capable of altering the lipid profile of the microbial cell membrane [47].”
From Effect of essential oils on pathogenic bacteria (2013) · cites this paper as [47]
In the citing paper
“It also acts against different bacterial enzymes, including ATPase, histidine carboxylase, amylase and protease [46,47].”
From Effect of essential oils on pathogenic bacteria (2013) · cites this paper as [47]
In the citing paper
“Non-specific inhibition of membrane-bound or -embedded enzymes can be caused by small hydrophobic molecules as a result of changes in the protein conformation.”
From Effect of essential oils on pathogenic bacteria (2013) · cites this paper as [47]
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Metadata
- Authors
- Wendakoon, C. N., & Sakaguchi, M.
- Affiliations
- Kyoto University (JP)
- Venue
- Journal of Food Protection
- Publisher
- Elsevier BV
- Published
- 1995-03
- Volume
- 58
- Issue
- 3
- Pages
- 280-283
- ISSN
- 0362-028X (ISSN-L)
- OpenAlex
- W2409189647
- Cited by
- 377
- References
- 0
- Citations by year
- 2026: 2 · 2025: 7 · 2024: 15 · 2023: 17 · 2022: 14 · 2021: 14 · 2020: 18 · 2019: 16 · 2018: 16 · 2017: 16 · 2016: 24 · 2015: 23 · 2014: 18 · 2013: 28 · 2012: 27
- FWCI
- 0.12
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Food Protection (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Polyamine Metabolism and Applications
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Life Sciences › Immunology and Microbiology › Applied Microbiology and Biotechnology › Antimicrobial agents and applications
- Keywords
- Enterobacter aerogenes, spices, histidine decarboxylase, lysine decarboxylase, ornithine decarboxylase, cinnamaldehyde, eugenol, Syzygium aromaticum, cinnamon, nutmeg, allspice, sage, antimicrobial food additives
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