Effects of Spirulina (Spirulina platensis) on dietary hypercho lesterolemia in rats
Open accessAbstract
The Sprague-Dawley-strain rats were devided and classified into four groups: (1) the rats fed on the basal diets, (2) the rats fed on the basal diets containing 1% cholesterol, (3) the rats fed on the basal diets containing 16% spirulina, and (4) the rats fed on the basal diets containing 16% spirulina and 1% cholesterol.The results obtained were as follows. Elevation in total cholesterol, LDL+VLDL cholesterol, and phosholipids in serum caused by cholesterol feeding (Group 2) were reduced clearly by feeding (Group 4). Fall' in HDL cholesterol level caused by cholesterol feeding (Group 2) was reduced by feeding spirulina (Group 4). It was expected from these results that spirulina may prevent dietary hypercholesterolemia and arteriosclerosis. And, dietary hypercholesterolemia caused by cholesterol feeding was cured by spirulina feeding.The fatty liver caused by high-fat and high-cholesterol diets was also cured rapidly by feeding spirulina.
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Green algae have been shown to regulate lipid and carbohydrate metabolism and to have cholesterol-lowering effects.
“Green algae have been shown to regulate lipid and carbohydrate metabolism [104] and to have cholesterol-lowering effects [105].”
From Application of Arthrospira platensis for Medicinal Purposes and the Food Industry: A Review of the Literature (2023) · cites this paper as [104]
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Evaluation of the toxicity of Arthrospira (Spirulina) platensis extract
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- Authors
- Kato
- Venue
- Nippon Eiyo Shokuryo Gakkaishi
- Published
- 1984
- Volume
- 37
- Issue
- 4
- Pages
- 323-332
- ISSN
- 0287-3516 (ISSN-L)
- 1883-2849
- OpenAlex
- W2514087837
- Cited by
- 36
- References
- 0
- Citations by year
- 2024: 2 · 2023: 2 · 2022: 2 · 2021: 2 · 2020: 3 · 2018: 1 · 2017: 2 · 2016: 2 · 2015: 1 · 2014: 1 · 2012: 1
- FWCI
- 0.00
- Type
- journal article
- Language
- ja
- Open access
- diamond
- doi.org
- Locations
- Nippon Eiyo Shokuryo Gakkaishi (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Health Sciences › Medicine › Surgery › Cholesterol and Lipid Metabolism
- Health Sciences › Medicine › Surgery › Natural Products and Biological Research
- Keywords
- Spirulina, dietary cholesterol, hypercholesterolemia, serum lipids, HDL cholesterol, LDL cholesterol, phospholipids, arteriosclerosis, hepatic steatosis, high-fat high-cholesterol diet, cholesterol-fed rats
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