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Cited by 2Schizophrenia research and treatmentMental Health Treatment and AccessMental Health and Psychiatry

Psychopathological profile and antipsychotic treatment may be linked to internalised stigma in schizophrenia – a cross-sectional study

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Rodak, Juliusz, Witusik, Andrzej, Nowakowska-Domagała, Katarzyna, Pietras, Tadeusz, Mokros, Łukasz·2018·Postępy Psychiatrii i Neurologii
DOI 10.5114/ppn.2018.77034
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Abstract

Purpose: The aim of this study was to assess the relationship between the internalised stigma of mental illness associated with the use of antipsychotic treatment and psychopathological profile among patients diagnosed with schizophrenia.Method: The study group comprised 64 patients diagnosed with schizophrenia.The Internalised Stigma of Mental Illness Inventory was used to assess the degree of self-stigmatisation in five aspects: Alienation, Stereotype Endorsement, Discrimination experience, Social withdrawal and Stigma resistance.The symptoms were assessed by a psychiatrist using the Clinical Assessment of Schizophrenic Syndromes Scale.Other variables of interest included data on current pharmacotherapy, body-mass index (BMI) and general functioning.Multivariate linear regression models were created to assess the association between variables of interest and ISMI subscale scores.Results were considered statistically significant when p < 0.05.Results: Zuclopenthixol, a long-acting injectable (LAI), was linked to greater Alienation, Stereotype endorsement and Discrimination experience, while risperidone LAI was associated with higher indices of Stereotype endorsement.Oral risperidone was linked to lower severity of Alienation and a greater level of Stigma resistance.A rise in the Lack of insight score predicted falls in Alienation, Stereotype endorsement, Discrimination experience and Social withdrawal scores.A rise in the Disturbances of Sense of Self score predicted rises in Alienation, Stereotype endorsement and Discrimination experience.

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  • Antipsychotic medication may damage the self-concept, with self-doubt, low self-esteem, and self-stigmatization contributing to poor subjective quality of life.

    “Furthermore, antipsychotic medication may damage the self-concept, with self-doubt, low self-esteem, and self-stigmatization contributing to poor subjective quality of life in individuals prescribed antipsychotic medication (Chou et al., 2014; Moritz et al., 2010; Rodak et al., 2018; Sajatovic & Jenkins, 2007).”

    From Narrative identity in the psychosis spectrum: A systematic review and developmental model (2021) · cites this paper as Rodak et al., 2018

    The Abstract reports associations between particular antipsychotics and internalised stigma in patients with schizophrenia, and the Introduction links internalised stigma with low self-esteem and quality of life. Neither passage establishes that medication damages self-concept or produces self-doubt; the Discussion explicitly says the cross-sectional study cannot establish causation. Page numbers were not available in our copy. (LLM, conf=0.86)

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Cited by

Sorted by citations

Authors
Rodak, J., Witusik, A., Nowakowska-Domagała, K., Pietras, T., & Mokros, Ł.
Affiliations
  • Jan Kochanowski University (PL)
  • Medical University of Lodz (PL)
Corresponding author
Mokros, Łukasz
ORCID
Venue
Postępy Psychiatrii i Neurologii
Publisher
Termedia Sp. z.o.o.
Published
2018
Volume
27
Issue
2
Pages
77-86
ISSN
1230-2813 (ISSN-L)
DOI
10.5114/ppn.2018.77034
OpenAlex
W2887922664
Cited by
2
References
7
Citations by year
2021: 1 · 2019: 1
FWCI
0.39
Type
journal article
Language
pl
Open access
Licence
cc-by-nc-nd
Locations
Postępy Psychiatrii i Neurologii (publishedVersion, cc-by-nc-nd)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
  • Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
Keywords
schizophrenia, self-stigma, antipsychotic drugs, long-acting injectable antipsychotics, zuclopenthixol, risperidone, alienation, stereotype endorsement, discrimination experiences, stigma resistance, social withdrawal, lack of insight, psychopathological profile

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