Changes in pharyngeal anatomy and apnea/hypopnea index after a mandibular advancement device
Open accessAbstract
Objectives: This study aimed to evaluate the therapeutic effcacy of custom-made mandibular advancement devices (MAD) in the control of primary snoring and sleep apnea and to correlate with anatomical changes identified through imaging tests. Methods: Patients (n = 17) diagnosed with sleep apnea or primary snoring were included in this study and subsequently treated with MADs. Changes were assessed using a polysomnographic study (PSG), the Epworth Sleepiness Scale (ESS), and an imaging study with computed tomography scanning (CT). Studies were performed before and after the use of MAD. Anteroposterior measurements were taken in the sagittal plane at the hard palate, glottis, and supraglottic levels along the hard palate axis. Afterward, measurements were taken in the axial plane at the same levels along the hard palate axis. Results: From the six recorded measurements, the airway caliber increased by five. However, these changes were significant only in two measurements (sagittal hard palate and axial supraglottic). Snoring was controlled in 16 of the 17 subjects. From these sixteen, 12 subjects had a correct opening of the airway at the hard palate level. Moreover, daytime sleepiness decreased in all subjects. Discussion: Present results suggest that sagittal hard palate and axial supraglottic opening after use of MAD are mainly responsible for eliminating snoring and improve sleep apnea.
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Studies incorporating polysomnography alongside structural assessment to evaluate functional outcomes of mandibular advancement in children are more limited in number.
“In contrast, studies incorporating polysomnography alongside structural assessment to evaluate functional outcomes of mandibular advancement in children are more limited in number [20–22, 42–45]”
From Long-Term Changes Following Orthopedic Mandibular Advancement Therapy in Pediatric Obstructive Sleep Apnea: a 7-Year Follow-up Study (2026) · cites this paper as [20]
The Materials and Methods sections (page unavailable) describe a study combining polysomnography with CT assessment after mandibular advancement, and the Discussion says imaging results in this area remain scarce. But the participants were 17 adults, and the paper does not establish that studies combining these assessments in children are limited in number. (LLM, conf=0.83)
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Fernández-Sanjuán, P., Alcaraz, M., Bosco, G., Pérez‐Martín, N., Morato, M., Lugo, R., Arrieta, J. J., Sanabria, J., Lago, M. R., & Plaza, G. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13051184 · Cited by 11 · see citing works
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- Authors
- Cortes-Mejia, J.-M., Boquete-Castro, A., Arana-Lechuga, Y., Terán-Pérez, G. J., Casarez-Cruz, K., González-Robles, R. O., & Velázquez-Moctezuma, J.
- Affiliations
- Sleep Disorders Clinic, Universidad Autónoma Metropolitana, Sleep Disorder Clinic - Mexico City - Ciudad De Mexico - Mexico.
- Postgraduate in dentistry. Catholic University of San Antonio. Murcia, Spain.
- Universidad Autónoma Metropolitana (MX)
- Neurosciences and Sleep Disorders Center., Sleep Disorder Clinic - Ciudad De Mexico - México.
- Instituto Nacional de Neurología y Neurocirugía (MX)
- Venue
- Sleep Science
- Publisher
- Georg Thieme Verlag KG
- Published
- 2022-03
- Volume
- 15
- Issue
- 01
- Pages
- 75-81
- ISSN
- 1984-0063 (ISSN-L)
- 1984-0659
- PMC
- PMC9153980
- OpenAlex
- W4282930724
- Cited by
- 5
- References
- 46
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 1 · 2023: 2
- FWCI
- 0.62
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- Locations
- Sleep Science (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Consejo Nacional de Ciencia y Tecnología
- Topics
- Health Sciences › Medicine › Physiology › Obstructive Sleep Apnea Research
- Health Sciences › Health Professions › Complementary and Manual Therapy › Temporomandibular Joint Disorders
- Health Sciences › Dentistry › Orthodontics › Orthodontics and Dentofacial Orthopedics
- Keywords
- mandibular advancement device, sleep apnea, snoring, airway caliber, apnea-hypopnea index, hard palate, supraglottic airway devices, daytime sleepiness
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