The DOI matches its Crossref record; 58 of the 58 references it cites were found in a registry or an index.
Testicular Cancer, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology
Abstract
Testicular cancer is relatively uncommon and accounts for <1% of all male tumors. However, it is the most common solid tumor in men between the ages of 20 and 34 years, and the global incidence has been steadily rising over the past several decades. Several risk factors for testicular cancer have been identified, including personal or family history of testicular cancer and cryptorchidism. Testicular germ cell tumors (GCTs) comprise 95% of malignant tumors arising in the testes and are categorized into 2 main histologic subtypes: seminoma and nonseminoma. Although nonseminoma is the more clinically aggressive tumor subtype, 5-year survival rates exceed 70% with current treatment options, even in patients with advanced or metastatic disease. Radical inguinal orchiectomy is the primary treatment for most patients with testicular GCTs. Postorchiectomy management is dictated by stage, histology, and risk classification; treatment options for nonseminoma include surveillance, systemic therapy, and nerve-sparing retroperitoneal lymph node dissection. Although rarely occurring, prognosis for patients with brain metastases remains poor, with >50% of patients dying within 1 year of diagnosis. This selection from the NCCN Guidelines for Testicular Cancer focuses on recommendations for the management of adult patients with nonseminomatous GCTs.
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Annual report to the nation on the status of cancer, part I: National cancer statistics
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“Testicular germ cell tumors (TGCTs) are the most common malignancy among men between 20 and 40 years of age, with a rising incidence [1].”
Background
Metadata
- Authors
- Gilligan, T., Lin, D. W., Aggarwal, R., Chism, D., Cost, N., Derweesh, I. H., Emamekhoo, H., Feldman, D. R., Geynisman, D. M., Hancock, S. L., LaGrange, C., Levine, E. G., Longo, T., Lowrance, W., McGregor, B., Monk, P., Picus, J., Pierorazio, P., Rais-Bahrami, S., Saylor, P., Sircar, K., Smith, D. C., Tzou, K., Vaena, D., Vaughn, D., Yamoah, K., Yamzon, J., Johnson-Chilla, A., Keller, J., & Pluchino, L. A.
- Venue
- Journal of the National Comprehensive Cancer Network
- Publisher
- Harborside Press, LLC
- Published
- 2019-12
- Volume
- 17
- Issue
- 12
- Pages
- 1529-1554
- ISSN
- 1540-1405 (ISSN-L)
- 1540-1413
- OpenAlex
- W2994187593
- Cited by
- 450
- References
- 58
- FWCI
- 55.96
- Type
- journal article
- Language
- en
- Open access
- closed
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- Gilligan, T., Lin, D. W., Aggarwal, R., Chism, D., Cost, N., Derweesh, I. H., Emamekhoo, H., Feldman, D. R., Geynisman, D. M., Hancock, S. L., LaGrange, C., Levine, E. G., Longo, T., Lowrance, W., McGregor, B., Monk, P., Picus, J., Pierorazio, P., Rais-Bahrami, S., . . . Pluchino, L. A. (2019). Testicular Cancer, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology. Journal of the National Comprehensive Cancer Network. https://doi.org/10.6004/jnccn.2019.0058
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.