The DOI matches its Crossref record; 59 of the 59 references it cites were found in a registry or an index.
Antibiotics for cancer treatment: A double-edged sword
Open accessAbstract
Various antibiotics have been used in the treatment of cancers, via their anti-proliferative, pro-apoptotic and anti-epithelial-mesenchymal-transition (EMT) capabilities. However, increasingly studies have indicated that antibiotics may also induce cancer generation by disrupting intestinal microbiota, which further promotes chronic inflammation, alters normal tissue metabolism, leads to genotoxicity and weakens the immune response to bacterial malnutrition, thereby adversely impacting cancer treatment. Despite the advent of high-throughput sequencing technology in recent years, the potential adverse effects of antibiotics on cancer treatments via causing microbial imbalance has been largely ignored. In this review, we discuss the double-edged sword of antibiotics in the field of cancer treatments, explore their potential mechanisms and provide solutions to reduce the potential negative effects of antibiotics.
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Metadata
- Authors
- Gao, Y., Shang, Q., Li, W., Guo, W., Stojadinovic, A., Mannion, C., Man, Y.-G., & Chen, T.
- Venue
- Journal of Cancer
- Publisher
- Ivyspring International Publisher
- Published
- 2020
- Volume
- 11
- Issue
- 17
- Pages
- 5135-5149
- ISSN
- 1837-9664 (ISSN-L)
- OpenAlex
- W3043831675
- Cited by
- 253
- References
- 59
- FWCI
- 9.27
- Type
- journal article
- Language
- en
- Open access
- gold
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
