The DOI matches its Crossref record; 54 of the 54 references it cites were found in a registry or an index.
Exosomes derived from platelet-rich plasma promote the re-epithelization of chronic cutaneous wounds via activation of YAP in a diabetic rat model
Open accessAbstract
Chronic wounds have become an economic, social, and public health burden and need advanced treatment.Platelet-rich plasma (PRP) has been used extensively in treatment of chronic wounds because it contains an abundance of growth factors secreted by platelets.The exosomes derived from PRP (PRP-Exos) have been proven to encapsulate principal growth factors from platelets.This study is the first to show that these exosomes may exert the function of PRP.PRP-Exos can effectively induce proliferation and migration of endothelial cells and fibroblasts to improve angiogenesis and re-epithelialization in chronic wounds.We regulated YAP to verify the PRP-Exos-dependent effect on fibroblast proliferation and migration through YAP activation.In vivo, we observed the cutaneous healing process in chronic wounds treated with PRP-Exos in a diabetic rat model.We provide evidence of the probable molecular mechanisms underlying the PRP effect on healing of chronic ulcers and describe a promising resource of growth factors from exosomes without species restriction.
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Cites
Isolation and Characterization of Exosomes from Cell Culture Supernatants and Biological Fluids
Théry, C., Amigorena, S., Raposo, G., & Clayton, A. (2006) · Current Protocols in Cell Biology · doi:10.1002/0471143030.cb0322s30 · Cited by 5,766
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
Melo, S. A., Luecke, L. B., Kahlert, C., Fernandez, A. F., Gammon, S. T., Kaye, J., LeBleu, V. S., Mittendorf, E. A., Weitz, J., Rahbari, N., et al. (2015) · Nature · doi:10.1038/nature14581 · Cited by 2,880
Wound healing and its impairment in the diabetic foot
Falanga, V. (2005) · The Lancet · doi:10.1016/s0140-6736(05)67700-8 · Cited by 2,639
Regulation of immune responses by extracellular vesicles
Robbins, P. D., & Morelli, A. E. (2014) · Nature Reviews Immunology · doi:10.1038/nri3622 · Cited by 2,260
Huang, J., Wu, S., Barrera, J., Matthews, K., & Pan, D. (2005) · Cell · doi:10.1016/j.cell.2005.06.007 · Cited by 1,863
Distinct fibroblast lineages determine dermal architecture in skin development and repair
Driskell, R. R., Lichtenberger, B. M., Hoste, E., Kretzschmar, K., Simons, B. D., Charalambous, M., Ferron, S. R., Herault, Y., Pavlovic, G., Ferguson-Smith, A. C., et al. (2013) · Nature · doi:10.1038/nature12783 · Cited by 1,291
Yap1 acts downstream of α-catenin to control epidermal proliferation
Schlegelmilch, K., Mohseni, M., Kirak, O., Pruszak, J., Rodriguez, J. R., Zhou, D., Kreger, B. T., Vasioukhin, V., Avruch, J., Brummelkamp, T. R., et al. (2011) · Cell · doi:10.1016/j.cell.2011.02.031 · Cited by 1,036
PI3K signalling: the path to discovery and understanding
Vanhaesebroeck, B., Stephens, L., & Hawkins, P. (2012) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3290 · Cited by 987
HucMSC-Exosome Mediated-Wnt4 Signaling Is Required for Cutaneous Wound Healing
Zhang, B., Wang, M., Gong, A., Zhang, X., Wu, X., Zhu, Y., Shi, H., Wu, L., Zhu, W., Qian, H., et al. (2015) · Stem Cells · doi:10.1002/stem.1771 · Cited by 792
Exosome-delivered microRNAs modulate the inflammatory response to endotoxin
Alexander, M., Hu, R., Runtsch, M. C., Kagele, D. A., Mosbruger, T. L., Tolmachova, T., Seabra, M. C., Round, J. L., Ward, D. M., & O’Connell, R. M. (2015) · Nature Communications · doi:10.1038/ncomms8321 · Cited by 769
Cited by
Therapeutically harnessing extracellular vesicles
Cheng, L., & Hill, A. F. (2022) · Nature Reviews Drug Discovery · doi:10.1038/s41573-022-00410-w · Cited by 737
Hu, Y., Rao, S.-S., Wang, Z.-X., Cao, J., Tan, Y.-J., Luo, J., Li, H.-M., Zhang, W.-S., Chen, C.-Y., & Xie, H. (2018) · Theranostics · doi:10.7150/thno.21234 · Cited by 574
Pranantyo, D., Yeo, C. K., Wu, Y., Fan, C., Xu, X., Yip, Y. S., Vos, M. I. G., Mahadevegowda, S. H., Lim, P. L. K., Yang, L., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-44968-y · Cited by 380
Yu, Y., Du, H., Wei, S., Feng, L., Li, J., Yao, F., Zhang, M., Hatch, G. M., & Chen, L. (2018) · Theranostics · doi:10.7150/thno.22565 · Cited by 330
Liu, W., Wang, Y., Gong, F., Rong, Y., Luo, Y., Tang, P., Zhou, Z., Zhou, Z., Xu, T., Jiang, T., et al. (2019) · Journal of Neurotrauma · doi:10.1089/neu.2018.5835 · Cited by 325
Metadata
- Authors
- Guo, S.-C., Tao, S.-C., Yin, W.-J., Qi, X., Yuan, T., & Zhang, C.-Q.
- Venue
- Theranostics
- Publisher
- Ivyspring International Publisher
- Published
- 2017
- Volume
- 7
- Issue
- 1
- Pages
- 81-96
- ISSN
- 1838-7640 (ISSN-L)
- OpenAlex
- W2551533129
- Cited by
- 513
- References
- 54
- FWCI
- 21.89
- Type
- journal article
- Language
- en
- Open access
- gold
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- Guo, S.-C., Tao, S.-C., Yin, W.-J., Qi, X., Yuan, T., & Zhang, C.-Q. (2017). Exosomes derived from platelet-rich plasma promote the re-epithelization of chronic cutaneous wounds via activation of YAP in a diabetic rat model. Theranostics. https://doi.org/10.7150/thno.16803
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