Cited by 89Nanoplatforms for cancer theranosticsNanoparticle-Based Drug DeliveryPhotodynamic Therapy Research Studies

Thermo- and pH-dual responsive polymeric micelles with upper critical solution temperature behavior for photoacoustic imaging-guided synergistic chemo-photothermal therapy against subcutaneous and metastatic breast tumors

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Yang, Zhe, Cheng, Rui, Zhao, Chenyang, Sun, Na, Luo, Huiyan, Chen, Ya, Liu, Zerong, Li, Xian +2 more·2018·Theranostics

Abstract

Herein, a pH- and thermo-dual responsive UCST micelle system was developed for delivering IR780 and DOX, which could achieve NIR laser-controlled drug release and PA imaging guidance for chemo-photothermal synergistic therapy of both primary breast tumors and their metastases.

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Crossref · 10.7150/thno.26195

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  • The pH difference between normal tissue/blood and the extracellular environment of the tumor is intrinsic, which has been widely used in drug sustained-release systems.

    “The pH difference between normal tissue/blood and the extracellular environment of the tumor is intrinsic, which has been widely used in drug sustained-release systems.40”

    From Smart nanoparticles for cancer therapy (2023) · cites this paper as [40]

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Authors
Yang, Z., Cheng, R., Zhao, C., Sun, N., Luo, H., Chen, Y., Liu, Z., Li, X., Liu, J., & Tian, Z.
Affiliations
  • Xi'an Jiaotong University (CN)
  • Sun Yat-sen University Cancer Center (CN)
  • Sun Yat-sen University (CN)
Corresponding author
Liu, Jie
Venue
Theranostics
Published
2018
Volume
8
Issue
15
Pages
4097-4115
ISSN
1838-7640 (ISSN-L)
OpenAlex
W2887002424
Cited by
89
References
36
Citations by year
2026: 5 · 2025: 3 · 2024: 10 · 2023: 8 · 2022: 15 · 2021: 15 · 2020: 16 · 2019: 15 · 2018: 2
FWCI
4.80
Type
journal article
Language
en
Open access
Licence
cc-by-nc
Locations
  • Theranostics (publishedVersion, cc-by-nc)
  • Europe PMC (PubMed Central) (publishedVersion, other-oa)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
  • Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Photodynamic Therapy Research Studies
Keywords
polymeric micelles, upper critical solution temperature, pH-responsive drug delivery, thermosensitive drug delivery, photoacoustic imaging, chemo-photothermal therapy, IR780, doxorubicin, breast cancer
MeSH terms
Animals, Breast Neoplasms, Combined Modality Therapy, Disease Models, Animal, Doxorubicin, Drug Carriers, Drug Therapy, Hydrogen-Ion Concentration, Hyperthermia, Induced, Indoles, Infrared Rays, Mice, Inbred BALB C, Micelles, Phototherapy, Polymers, Temperature, Nanostructures, Photoacoustic Techniques

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