The DOI matches its Crossref record.
Insulin-like Growth Factors in Health and Disease
Abstract
The insulin-like growth factor (IGF) family of peptides, binding proteins, and receptors are ubiquitous and important for normal human growth and development. Modern techniques including specific radioimmunoassays, radioreceptor assays and recombinant DNA technology have improved our understanding of the role of IGFs in growth and development. In addition to enhancing our understanding of normal physiology, these techniques assess changes in these hormones, binding proteins, and receptors in pathologic conditions including growth retardation, acromegaly, malnutrition, diabetes, and malignancy. Further, these studies have led to improvement in the assessment of responses to certain therapies used in the treatment of these diseases and may lead to improvements in these therapies.
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Citations
Cited by
Le Roith, D. (1997) · New England Journal of Medicine · doi:10.1056/nejm199702273360907 · Cited by 897
Self-citationInsulin-like Growth Factors and Cancer
LeRoith, D., Baserga, R., Helman, L., & Roberts Jr., C. T. (1995) · Annals of Internal Medicine · doi:10.7326/0003-4819-122-1-199501010-00009 · Cited by 317
Self-citationHormonal profile in patients with congestive heart failure
Kontoleon, P. E., Anastasiou-Nana, M. I., Papapetrou, P. D., Alexopoulos, G., Ktenas, V., Rapti, A. C., Tsagalou, E. P., & Nanas, J. N. (2003) · International Journal of Cardiology · doi:10.1016/s0167-5273(02)00212-7 · Cited by 145
Insulin-like growth factors and subsequent risk of mortality in the United States
Saydah, S., Graubard, B., Ballard-Barbash, R., & Berrigan, D. (2007) · American Journal of Epidemiology · doi:10.1093/aje/kwm124 · Cited by 71
Impact of physical exercise on endocrine aging
Janssen, J. A. M. J. L. (2016) · Frontiers of hormone research · doi:10.1159/000445158 · Cited by 37
Metadata
- Authors
- LeRoith, D., Clemmons, D., Nissley, P., & Rechler, M. M.
- Venue
- Annals of Internal Medicine
- Publisher
- American College of Physicians
- Published
- 1992-05-15
- Volume
- 116
- Issue
- 10
- Pages
- 854-862
- ISSN
- 0003-4819 (ISSN-L)
- 1539-3704
- OpenAlex
- W2032759611
- Cited by
- 160
- References
- 0
- FWCI
- 10.75
- Type
- journal article
- Language
- en
- Open access
- closed
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- LeRoith, D., Clemmons, D., Nissley, P., & Rechler, M. M. (1992). Insulin-like Growth Factors in Health and Disease. Annals of Internal Medicine. https://doi.org/10.7326/0003-4819-116-10-854
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
