The DOI matches its Crossref record.
Thrombosis in Patients with the Lupus Anticoagulant
Abstract
A retrospective study was carried out to determine the frequency of thrombosis in patients with the lupus anticoagulant. Thirty-five patients fulfilled laboratory criteria for the diagnosis of the lupus anticoagulant. Eight of these patients had evidence of clinically significant thrombosis while their plasma showed a prolonged partial thromboplastin time due to the anticoagulant. Four of the patients wity thrombosis had concurrent autoimmune disease and three other patients were receiving phenothiazine medication. Moderate thrombocytopenia was noted in four patients with thrombosis. None of the patients with the lupus anticoagulant bled abnormally. This study suggests that patients with the lupus anticoagulant may be at increased risk of thrombosis.
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Citations
Cited by
Harris, E. N., Boey, M. L., Mackworth-Young, C. G., Gharavi, A. E., Patel, B. M., Loizou, S., & Hughes, G. R. V. (1983) · The Lancet · doi:10.1016/s0140-6736(83)91267-9 · Cited by 1,383
Antiphospholipid thrombosis: clinical course after the first thrombotic event in 70 patients
Rosove, M. H., & Brewer, P. M. C. (1992) · Annals of Internal Medicine · doi:10.7326/0003-4819-117-4-303 · Cited by 700
Boey, M. L., Colaco, C. B., Gharavi, A. E., Elkon, K. B., Loizou, S., & Hughes, G. R. (1983) · BMJ · doi:10.1136/bmj.287.6398.1021 · Cited by 508
Immunology and clinical importance of antiphospholipid antibodies
McNeil, H. P., Chesterman, C. N., & Krilis, S. A. (1991) · Advances in immunology · doi:10.1016/s0065-2776(08)60777-4 · Cited by 481
The use of the dilute Russell viper venom time for the diagnosis of lupus anticoagulants
Thiagarajan, P., Pengo, V, & Shapiro, S. (1986) · Blood · doi:10.1182/blood.v68.4.869.869 · Cited by 422
Metadata
- Authors
- MUEH, J. R., HERBST, K. D., & RAPAPORT, S. I.
- Venue
- Annals of Internal Medicine
- Publisher
- American College of Physicians
- Published
- 1980-02-01
- Volume
- 92
- Issue
- 2_Part_1
- Pages
- 156-159
- ISSN
- 0003-4819 (ISSN-L)
- 1539-3704
- OpenAlex
- W2113698539
- Cited by
- 496
- References
- 0
- FWCI
- 15.18
- Type
- journal article
- Language
- en
- Open access
- closed
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- MUEH, J. R., HERBST, K. D., & RAPAPORT, S. I. (1980). Thrombosis in Patients with the Lupus Anticoagulant. Annals of Internal Medicine. https://doi.org/10.7326/0003-4819-92-2-156
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
