The DOI matches its Crossref record; 96 of the 96 references it cites were found in a registry or an index.
Calcium specificity signaling mechanisms in abscisic acid signal transduction in Arabidopsis guard cells
Open accessAbstract
A central question is how specificity in cellular responses to the eukaryotic second messenger Ca2+ is achieved. Plant guard cells, that form stomatal pores for gas exchange, provide a powerful system for in depth investigation of Ca2+-signaling specificity in plants. In intact guard cells, abscisic acid (ABA) enhances (primes) the Ca2+-sensitivity of downstream signaling events that result in activation of S-type anion channels during stomatal closure, providing a specificity mechanism in Ca2+-signaling. However, the underlying genetic and biochemical mechanisms remain unknown. Here we show impairment of ABA signal transduction in stomata of calcium-dependent protein kinase quadruple mutant plants. Interestingly, protein phosphatase 2Cs prevent non-specific Ca2+-signaling. Moreover, we demonstrate an unexpected interdependence of the Ca2+-dependent and Ca2+-independent ABA-signaling branches and the in planta requirement of simultaneous phosphorylation at two key phosphorylation sites in SLAC1. We identify novel mechanisms ensuring specificity and robustness within stomatal Ca2+-signaling on a cellular, genetic, and biochemical level.
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Cited by
Protein kinases in plant responses to drought, salt, and cold stress
Chen, X., Ding, Y., Yang, Y., Song, C., Wang, B., Yang, S., Guo, Y., & Gong, Z. (2021) · Journal of Integrative Plant Biology · doi:10.1111/jipb.13061 · Cited by 608
Mechanisms of abscisic acid-mediated control of stomatal aperture
Munemasa, S., Hauser, F., Park, J., Waadt, R., Brandt, B., & Schroeder, J. I. (2015) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2015.10.010 · Cited by 567
Self-citationSignaling mechanisms in abscisic acid-mediated stomatal closure
Hsu, P., Dubeaux, G., Takahashi, Y., & Schroeder, J. I. (2021) · The Plant Journal · doi:10.1111/tpj.15067 · Cited by 546
Self-citationPlant salt response: Perception, signaling, and tolerance
Xiao, F., & Zhou, H. (2023) · Frontiers in Plant Science · doi:10.3389/fpls.2022.1053699 · Cited by 286
Metadata
- Authors
- Brandt, B., Munemasa, S., Wang, C., Nguyen, D., Yong, T., Yang, P. G., Poretsky, E., Belknap, T. F., Waadt, R., Alemán, F., & Schroeder, J. I.
- Venue
- eLife
- Publisher
- eLife Sciences Publications, Ltd
- Published
- 2015-07-20
- Volume
- 4
- Pages
- e10328-e10328
- ISSN
- 2050-084X (ISSN-L)
- OpenAlex
- W1892997619
- Cited by
- 280
- References
- 96
- FWCI
- 37.41
- Type
- journal article
- Language
- en
- Update notices
- correction (2015-07-29)
- Open access
- gold
- Licence
- creativecommons.org/licenses/by/4.0/ (vor)
- creativecommons.org/licenses/by/4.0/ (am)
- creativecommons.org/licenses/by/4.0/ (tdm)
- Funders
- National Institutes of Health (NIH) (GM060396-ES010337)
- National Science Foundation (NSF) (MCB1414339)
- German Academic Exchange Service (PhD Fellowship)
- Japan Society for the Promotion of Science (JSPS) (Postdoctoral fellowship)
- U.S. Department of Energy (DE-FG02-03ER15449)
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- Brandt, B., Munemasa, S., Wang, C., Nguyen, D., Yong, T., Yang, P. G., Poretsky, E., Belknap, T. F., Waadt, R., Alemán, F., & Schroeder, J. I. (2015). Calcium specificity signaling mechanisms in abscisic acid signal transduction in Arabidopsis guard cells. eLife. https://doi.org/10.7554/elife.03599
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