Effect of cannabis use on PTSD treatment outcomes in veterans
Open accessAbstract
INTRODUCTION: Researchers have found anandamide (an endocannabinoid) and cannabinoid type 1 receptor activation encourages extinction of aversive memories. Some theorize cannabinoids such as those in cannabis may provide a new treatment approach for PTSD, while others suggest it may worsen symptomology. The objective of the current study was to determine if cannabis use impacts the success of evidence-based intensive outpatient PTSD treatment in a veteran population. METHODS: A list of veterans enrolled in the Battle Creek Veterans' Affairs Medical Center outpatient PTSD Clinical Team Clinic between October 1st, 2008 and October 1st, 2016 was obtained, and a random sample was identified. Study participants were veterans aged 18 to 85 years, with at least 2 PTSD Checklist scores, and a diagnosis of PTSD. Data collected included mental health medications, type and number of evidence-based psychotherapy used, and presence of co-occurring behavioral health diagnoses. The cannabis use group was compared to the no-cannabis-use group, and differences in variables pertaining to the relative number of treatment successes and failures was evaluated for statistical and clinical significance. RESULTS: The majority of patients were white (87.1%) and male (95%). The success rate was similar between the cannabis and no-cannabis-use groups (51.9% and 51.4%, respectively). DISCUSSION: The current study did not show that a predominantly white male veteran sample diagnosed with PTSD differed in intensive PTSD treatment success or failure based on cannabis use.
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Some studies have failed to find an association between cannabis use and PTSD treatment outcomes.
“However, other studies have failed to find an association between cannabis use and PTSD treatment outcomes (De Aquino et al., 2020; Hale et al., 2021; Petersen et al., 2021; Ruglass, Shevorykin et al., 2017).”
From Cannabis use and trauma-focused treatment for co-occurring posttraumatic stress disorder and substance use disorders: A meta-analysis of individual patient data (2024) · cites this paper as Petersen et al., 2021
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- Authors
- Petersen, M., Koller, K., Straley, C., & Reed, E.
- Affiliations
- Ferris State University (US)
- Battle Creek VA Medical Center (US)
- Corresponding author
- Petersen, Meagan
- Venue
- Mental Health Clinician
- Published
- 2021-07-01
- Volume
- 11
- Issue
- 4
- Pages
- 238-242
- ISSN
- 2168-9709 (ISSN-L)
- PMC
- PMC8287864
- OpenAlex
- W3185354495
- Cited by
- 5
- References
- 13
- Citations by year
- 2024: 2 · 2023: 2 · 2022: 1
- FWCI
- 0.85
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Mental Health Clinician (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
- Health Sciences › Medicine › Pharmacology › Cannabis and Cannabinoid Research
- Social Sciences › Psychology › Clinical Psychology › Migration, Health and Trauma
- Keywords
- cannabis use, post-traumatic stress disorder, veterans, intensive outpatient treatment, treatment outcomes, endocannabinoids, CB1 receptor, memory extinction, psychotherapy, psychiatric medication
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