Standaert, David G.

Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy

Obeso, J. A., Stamelou, M., Goetz, C. G., Poewe, W., Lang, A. E., Weintraub, D., Burn, D., Halliday, G. M., Bezard, E., Przedborski, S., et al. (2017) · Movement Disorders

Parkinson's Disease Mechanisms and TreatmentsNeurology and Historical Studies

Cited by 859

Continuous intrajejunal infusion of levodopa-carbidopa intestinal gel for patients with advanced Parkinson's disease: a randomised, controlled, double-blind, double-dummy study

Olanow, C. W., Kieburtz, K., Odin, P., Espay, A. J., Standaert, D. G., Fernandez, H. H., Vanagunas, A., Othman, A. A., Widnell, K. L., Robieson, W. Z., et al. (2014) · The Lancet Neurology

Parkinson's Disease Mechanisms and TreatmentsDeep Brain Stimulation and Movement Disorders

Cited by 716

Monitoring Motor Fluctuations in Patients With Parkinson's Disease Using Wearable Sensors

Patel, S., Lorincz, K., Hughes, R., Huggins, N., Growdon, J., Standaert, D., Akay, M., Dy, J., Welsh, M., & Bonato, P. (2009) · IEEE Transactions on Information Technology in Biomedicine

Context-Aware Activity Recognition SystemsArtificial Intelligence in Healthcare

Cited by 623

LRRK2 Inhibition Attenuates Microglial Inflammatory Responses

Moehle, M. S., Webber, P. J., Tse, T., Sukar, N., Standaert, D. G., DeSilva, T. M., Cowell, R. M., & West, A. B. (2012) · The Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsParkinson's Disease Mechanisms and Treatments

Cited by 463

MHCII Is Required for -Synuclein-Induced Activation of Microglia, CD4 T Cell Proliferation, and Dopaminergic Neurodegeneration

Harms, A. S., Cao, S., Rowse, A. L., Thome, A. D., Li, X., Mangieri, L. R., Cron, R. Q., Shacka, J. J., Raman, C., & Standaert, D. G. (2013) · Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsParkinson's Disease Mechanisms and Treatments

Cited by 406

α-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson’s disease

Lindestam Arlehamn, C. S., Dhanwani, R., Pham, J., Kuan, R., Frazier, A., Rezende Dutra, J., Phillips, E., Mallal, S., Roederer, M., Marder, K. S., et al. (2020) · Nature Communications

Parkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 386

Metagenomics of Parkinson’s disease implicates the gut microbiome in multiple disease mechanisms

Wallen, Z. D., Demirkan, A., Twa, G., Cohen, G., Dean, M. N., Standaert, D. G., Sampson, T. R., & Payami, H. (2022) · Nature Communications

Gut microbiota and healthParkinson's Disease Mechanisms and Treatments

Cited by 346

Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases

Espay, A. J., Vizcarra, J. A., Marsili, L., Lang, A. E., Simon, D. K., Merola, A., Josephs, K. A., Fasano, A., Morgante, F., Savica, R., et al. (2019) · Neurology

Parkinson's Disease Mechanisms and TreatmentsAlzheimer's disease research and treatments

Cited by 274

Characterizing Dysbiosis of Gut Microbiome in PD: Evidence for Overabundance of Opportunistic Pathogens

Wallen, Z. D., Appah, M., Dean, M. N., Sesler, C. L., Factor, S. A., Molho, E., Zabetian, C. P., Standaert, D. G., & Payami, H. (2020) · npj Parkinson s Disease

Gut microbiota and healthParkinson's Disease Mechanisms and Treatments

Cited by 252

Role of α-Synuclein in Inducing Innate and Adaptive Immunity in Parkinson Disease

Allen Reish, H. E., & Standaert, D. G. (2015) · Journal of Parkinson’s Disease

Parkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 244

Peripheral monocyte entry is required for alpha-Synuclein induced inflammation and neurodegeneration in a model of Parkinson disease

Harms, A. S., Thome, A. D., Yan, Z., Schonhoff, A. M., Williams, G. P., Li, X., Liu, Y., Qin, H., Benveniste, E. N., & Standaert, D. G. (2018) · Experimental Neurology

Parkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 236

Absence of α-synuclein mRNA expression in normal and multiple system atrophy oligodendroglia

Miller, D. W., Johnson, J. M., Solano, S. M., Hollingsworth, Z. R., Standaert, D. G., & Young, A. B. (2005) · Journal of Neural Transmission

Parkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 198

Alterations of striatal NMDA receptor subunits associated with the development of dyskinesia in the MPTP-lesioned primate model of Parkinson's disease

Hallett, P. J., Dunah, A. W., Ravenscroft, P., Zhou, S., Bezard, E., Crossman, A. R., Brotchie, J. M., & Standaert, D. G. (2005) · Neuropharmacology

Parkinson's Disease Mechanisms and TreatmentsDeep Brain Stimulation and Movement Disorders

Cited by 192

Border-associated macrophages mediate the neuroinflammatory response in an alpha-synuclein model of Parkinson disease

Schonhoff, A. M., Figge, D. A., Williams, G. P., Jurkuvenaite, A., Gallups, N. J., Childers, G. M., Webster, J. M., Standaert, D. G., Goldman, J. E., & Harms, A. S. (2023) · Nature Communications

Neuroinflammation and Neurodegeneration MechanismsParkinson's Disease Mechanisms and Treatments

Cited by 161

Complex alteration of NMDA receptors in transgenic Huntington's disease mouse brain: analysis of mRNA and protein expression, plasma membrane association, interacting proteins, and phosphorylation

Luthi-Carter, R., Apostol, B. L., Dunah, A. W., DeJohn, M. M., Farrell, L. A., Bates, G. P., Young, A. B., Standaert, D. G., Thompson, L. M., & Cha, J.-H. J. (2003) · Neurobiology of Disease

Neuroscience and Neuropharmacology ResearchGenetic Neurodegenerative Diseases

Cited by 104

T cell infiltration in both human multiple system atrophy and a novel mouse model of the disease

Williams, G. P., Marmion, D. J., Schonhoff, A. M., Jurkuvenaite, A., Won, W.-J., Standaert, D. G., Kordower, J. H., & Harms, A. S. (2020) · Acta Neuropathologica

Neuroinflammation and Neurodegeneration MechanismsParkinson's Disease Mechanisms and Treatments

Cited by 102

Exploring Human-Genome Gut-Microbiome Interaction in Parkinson’s Disease

Wallen, Z. D., Stone, W. J., Factor, S. A., Molho, E., Zabetian, C. P., Standaert, D. G., & Payami, H. (2021) · npj Parkinson s Disease

Parkinson's Disease Mechanisms and TreatmentsGut microbiota and health

Cited by 41

Alpha-synuclein–mediated DNA damage, STING activation, and neuroinflammation in Parkinson’s disease

Standaert, D. G., & Childers, G. M. (2022) · Proceedings of the National Academy of Sciences

Parkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 40

Alpha synuclein overexpression can drive microbiome dysbiosis in mice

Sampson, T. R., Wallen, Z. D., Won, W.-J., Standaert, D. G., Payami, H., & Harms, A. S. (2025) · Scientific Reports

Gut microbiota and healthParkinson's Disease Mechanisms and Treatments

Cited by 11