Characterizing Dysbiosis of Gut Microbiome in PD: Evidence for Overabundance of Opportunistic Pathogens

DADA2: High–resolution sample inference from Illumina amplicon data

Callahan, B. J., McMurdie, P. J., Rosen, M. J., Han, A. W., Johnson, A. J. A., & Holmes, S. P. (2016) · Nature Methods · doi:10.1038/nmeth.3869 · Cited by 35,698 · see citing works

Cutadapt removes adapter sequences from high-throughput sequencing reads

Martin, M. (2011) · EMBnet.journal · doi:10.14806/ej.17.1.200 · Cited by 33,889 · see citing works

Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2

Bolyen, E., Rideout, J. R., Dillon, M. R., Bokulich, N. A., Abnet, C. C., Al-Ghalith, G. A., Alexander, H., Alm, E. J., Arumugam, M., Asnicar, F., et al. (2019) · Nature Biotechnology · doi:10.1038/s41587-019-0209-9 · Cited by 23,742 · see citing works

Fast unfolding of communities in large networks

Blondel, V. D., Guillaume, J.-L., Lambiotte, R., & Lefebvre, E. (2008) · Journal of Statistical Mechanics: Theory and Experiment · doi:10.1088/1742-5468/2008/10/p10008 · Cited by 21,424 · see citing works

phyloseq: An R Package for Reproducible Interactive Analysis and Graphics of Microbiome Census Data

McMurdie, P. J., & Holmes, S. (2013) · PLoS ONE · doi:10.1371/journal.pone.0061217 · Cited by 21,013 · see citing works

Naive Bayesian Classifier for Rapid Assignment of rRNA Sequences into the New Bacterial Taxonomy

Wang, Q., Garrity, G. M., Tiedje, J. M., & Cole, J. R. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.00062-07 · Cited by 19,770 · see citing works

A new method for non-parametric multivariate analysis of variance

Anderson, M. J. (2001) · Austral Ecology · doi:10.1111/j.1442-9993.2001.01070.pp.x · Cited by 13,828 · see citing works

APE: Analyses of Phylogenetics and Evolution in R language

Paradis, E., Claude, J., & Strimmer, K. (2004) · Bioinformatics · doi:10.1093/bioinformatics/btg412 · Cited by 12,037 · see citing works

Gephi: An Open Source Software for Exploring and Manipulating Networks

Bastian, M., Heymann, S., & Jacomy, M. (2009) · Proceedings of the International AAAI Conference on Web and Social Media · doi:10.1609/icwsm.v3i1.13937 · Cited by 11,675 · see citing works

Staging of brain pathology related to sporadic Parkinson’s disease

Braak, H., Tredici, K. D., Rüb, U., de Vos, R. A. I., Jansen Steur, E. N. H., & Braak, E. (2003) · Neurobiology of Aging · doi:10.1016/s0197-4580(02)00065-9 · Cited by 10,777 · see citing works

A metagenome-wide association study of gut microbiota in type 2 diabetes

Qin, J., Li, Y., Cai, Z., Li, S., Zhu, J., Zhang, F., Liang, S., Zhang, W., Guan, Y., Shen, D., et al. (2012) · Nature · doi:10.1038/nature11450 · Cited by 6,762 · see citing works

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

Furusawa, Y., Obata, Y., Fukuda, S., Endo, T. A., Nakato, G., Takahashi, D., Nakanishi, Y., Uetake, C., Kato, K., Kato, T., et al. (2013) · Nature · doi:10.1038/nature12721 · Cited by 5,549 · see citing works

A Greedy Algorithm for Aligning DNA Sequences

Zhang, Z., Schwartz, S., Wagner, L., & Miller, W. (2000) · Journal of Computational Biology · doi:10.1089/10665270050081478 · Cited by 5,459 · see citing works

phangorn: phylogenetic analysis in R

Schliep, K. P. (2010) · Bioinformatics · doi:10.1093/bioinformatics/btq706 · Cited by 3,678 · see citing works

Gut microbiota regulate motor deficits and neuroinflammation in a model of Parkinson's disease

Sampson, T. R., Debelius, J. W., Thron, T., Janssen, S., Shastri, G. G., Ilhan, Z. E., Challis, C., Schretter, C. E., Rocha, S., Gradinaru, V., et al. (2016) · Cell · doi:10.1016/j.cell.2016.11.018 · Cited by 3,622 · see citing works

Microbiome Datasets Are Compositional: And This Is Not Optional

Gloor, G. B., Macklaim, J. M., Pawlowsky-Glahn, V., & Egozcue, J. J. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.02224 · Cited by 3,044 · cited 2× · see citing works

ForceAtlas2, a Continuous Graph Layout Algorithm for Handy Network Visualization Designed for the Gephi Software

Jacomy, M., Venturini, T., Heymann, S., & Bastian, M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0098679 · Cited by 2,909 · see citing works

Waste Not, Want Not: Why Rarefying Microbiome Data Is Inadmissible

McMurdie, P. J., & Holmes, S. (2014) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1003531 · Cited by 2,891 · see citing works

Review article: the role of butyrate on colonic function

HAMER, H. M., JONKERS, D., VENEMA, K., VANHOUTVIN, S., TROOST, F. J., & BRUMMER, R. ‐. (2008) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2007.03562.x · Cited by 2,721 · see citing works

Inferring Correlation Networks from Genomic Survey Data

Friedman, J., & Alm, E. J. (2012) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1002687 · Cited by 2,688 · see citing works

Population-level analysis of gut microbiome variation

Falony, G., Joossens, M., Vieira-Silva, S., Wang, J., Darzi, Y., Faust, K., Kurilshikov, A., Bonder, M. J., Valles-Colomer, M., Vandeputte, D., et al. (2016) · Science · doi:10.1126/science.aad3503 · Cited by 2,400 · see citing works

Normalization and microbial differential abundance strategies depend upon data characteristics

Weiss, S. J., Xu, Z. Z., Peddada, S. D., Amir, A., Bittinger, K. L., González, A., Lozupone, C., Zaneveld, J., Vázquez‐Baeza, Y., Birmingham, A., et al. (2017) · Microbiome · doi:10.1186/s40168-017-0237-y · Cited by 2,121 · see citing works

Gut microbiota are related to Parkinson's disease and clinical phenotype

Scheperjans, F., Aho, V., Pereira, P. A. B., Koskinen, K., Paulin, L., Pekkonen, E., Haapaniemi, E., Kaakkola, S., Eerola‐Rautio, J., Pohja, M., et al. (2015) · Movement Disorders · doi:10.1002/mds.26069 · Cited by 1,968 · see citing works

Analysis of composition of microbiomes: a novel method for studying microbial composition

Mandal, S., Van Treuren, W., White, R. A., Eggesbø, M., Knight, R., & Peddada, S. D. (2015) · Microbial Ecology in Health & Disease · doi:10.3402/mehd.v26.27663 · Cited by 1,942 · see citing works

Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity

Zhernakova, A., Kurilshikov, A., Bonder, M. J., Tigchelaar, E. F., Schirmer, M., Vatanen, T., Mujagic, Z., Vila, A. V., Falony, G., Vieira-Silva, S., et al. (2016) · Science · doi:10.1126/science.aad3369 · Cited by 1,914 · see citing works

Idiopathic Parkinson's disease: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen

Braak, H., R�b, U., Gai, W. P., & Del Tredici, K. (2003) · Journal of Neural Transmission · doi:10.1007/s00702-002-0808-2 · Cited by 1,683 · see citing works

The pros, cons, and many unknowns of probiotics

Suez, J., Zmora, N., Segal, E., & Elinav, E. (2019) · Nature Medicine · doi:10.1038/s41591-019-0439-x · Cited by 1,398 · see citing works

Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson’s Disease

Kim, S., Kwon, S.-H., Kam, T.-I., Panicker, N., Karuppagounder, S. S., Lee, S., Lee, J. H., Kim, W. R., Kook, M., Foss, C. A., et al. (2019) · Neuron · doi:10.1016/j.neuron.2019.05.035 · Cited by 1,397 · see citing works

Potential beneficial effects of butyrate in intestinal and extraintestinal diseases

Canani, R. B. (2011) · World Journal of Gastroenterology · doi:10.3748/wjg.v17.i12.1519 · Cited by 1,381 · see citing works

Colonic bacterial composition in Parkinson's disease

Keshavarzian, A., Green, S. J., Engen, P. A., Voigt, R. M., Naqib, A., Forsyth, C. B., Mutlu, E., & Shannon, K. M. (2015) · Movement Disorders · doi:10.1002/mds.26307 · Cited by 1,281 · see citing works

Short chain fatty acids and gut microbiota differ between patients with Parkinson's disease and age-matched controls

Unger, M. M., Spiegel, J., Dillmann, K.-U., Grundmann, D., Philippeit, H., Bürmann, J., Faßbender, K., Schwiertz, A., & Schäfer, K.-H. (2016) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2016.08.019 · Cited by 1,159 · see citing works

Associating microbiome composition with environmental covariates using generalized UniFrac distances

Chen, J., Bittinger, K. L., Charlson, E. S., Hoffmann, C., Lewis, J. D., Wu, G. D., Collman, R. G., Bushman, F. D., & Li, H. (2012) · Bioinformatics · doi:10.1093/bioinformatics/bts342 · Cited by 1,147 · see citing works

Bioconductor Workflow for Microbiome Data Analysis: from raw reads to community analyses

Callahan, B. J., Sankaran, K., Fukuyama, J., McMurdie, P. J., & Holmes, S. (2016) · F1000Research · doi:10.12688/f1000research.8986.2 · Cited by 1,113 · see citing works

A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci

Chang, D., Nalls, M. A., Hallgrímsdóttir, I. B., Hunkapiller, J., van der Brug, M., Cai, F., International Parkinson's Disease Genomics Consortium, 23andMe Research Team, Kerchner, G. A., Ayalon, G., et al. (2017) · Nature Genetics · doi:10.1038/ng.3955 · Cited by 1,112 · see citing works

Bifidobacteria and Their Role as Members of the Human Gut Microbiota

O’Callaghan, A. A., & van Sinderen, D. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.00925 · Cited by 1,108 · see citing works

Increased Intestinal Permeability Correlates with Sigmoid Mucosa alpha-Synuclein Staining and Endotoxin Exposure Markers in Early Parkinson's Disease

Forsyth, C. B., Shannon, K. M., Kordower, J. H., Voigt, R. M., Shaikh, M., Jaglin, J. A., Estes, J. D., Dodiya, H. B., & Keshavarzian, A. (2011) · PLoS ONE · doi:10.1371/journal.pone.0028032 · Cited by 974 · see citing works

Risk and safety of probiotics

Doron, S., & Snydman, D. R. (2015) · Clinical Infectious Diseases · doi:10.1093/cid/civ085 · Cited by 942 · see citing works

Parkinson's disease and Parkinson's disease medications have distinct signatures of the gut microbiome

Hill‐Burns, E. M., Debelius, J. W., Morton, J. T., Wissemann, W. T., Lewis, M. R., Wallen, Z. D., Peddada, S. D., Factor, S. A., Molho, E., Zabetian, C. P., et al. (2017) · Movement Disorders · doi:10.1002/mds.26942 · Cited by 874 · see citing works

The Human Gut Microbiome: From Association to Modulation

Schmidt, T. S. B., Raes, J., & Bork, P. (2018) · Cell · doi:10.1016/j.cell.2018.02.044 · Cited by 845 · see citing works

Vagotomy and subsequent risk of <scp>P</scp> arkinson's disease

Svensson, E., Horváth‐Puhó, E., Thomsen, R. W., Djurhuus, J. C., Pedersen, L., Borghammer, P., & Sørensen, H. T. (2015) · Annals of Neurology · doi:10.1002/ana.24448 · Cited by 806 · see citing works

Discovery and inhibition of an interspecies gut bacterial pathway for Levodopa metabolism

Maini Rekdal, V., Bess, E. N., Bisanz, J. E., Turnbaugh, P. J., & Balskus, E. P. (2019) · Science · doi:10.1126/science.aau6323 · Cited by 753 · see citing works

Functional implications of microbial and viral gut metagenome changes in early stage L-DOPA-naive Parkinson's disease patients

Bedarf, J. R., Hildebrand, F., Coelho, L. P., Sunagawa, S., Bahram, M., Goeser, F., Bork, P., & Wüllner, U. (2017) · Genome Medicine · doi:10.1186/s13073-017-0428-y · Cited by 642 · see citing works

The nasal and gut microbiome in Parkinson's disease and idiopathic rapid eye movement sleep behavior disorder

Heintz‐Buschart, A., Pandey, U., Wicke, T., Sixel‐Döring, F., Janzen, A., Sittig‐Wiegand, E., Trenkwalder, C., Oertel, W. H., Mollenhauer, B., & Wilmes, P. (2018) · Movement Disorders · doi:10.1002/mds.27105 · Cited by 554 · see citing works

Intestinal dysbiosis and lowered serum lipopolysaccharide-binding protein in Parkinson's disease

Hasegawa, S., Goto, S., Tsuji, H., Okuno, T., Asahara, T., Nomoto, K., Shibata, A., Fujisawa, Y., Minato, T., Okamoto, A., et al. (2015) · PLOS ONE · doi:10.1371/journal.pone.0142164 · Cited by 523 · see citing works

Bacteriology of Moderate-to-Severe Diabetic Foot Infections and In Vitro Activity of Antimicrobial Agents

Citron, D. M., Goldstein, E. J. C., Merriam, C. V., Lipsky, B. A., & Abramson, M. A. (2007) · Journal of Clinical Microbiology · doi:10.1128/jcm.00551-07 · Cited by 510 · see citing works

Intestinal infection triggers Parkinson's disease-like symptoms in Pink1(-/-) mice

Matheoud, D., Cannon, T., Voisin, A., Penttinen, A.-M., Ramet, L., Fahmy, A. M., Ducrot, C., Laplante, A., Bourque, M.-J., Zhu, L., et al. (2019) · Nature · doi:10.1038/s41586-019-1405-y · Cited by 496 · see citing works

Analysis of Gut Microbiota in Patients with Parkinson’s Disease

Petrov, V. A., Saltykova, I. V., Zhukova, I. A., Alifirova, V. M., Zhukova, N. G., Dorofeeva, Y. B., Tyakht, A. V., Kovarsky, B. A., Alekseev, D. G., Kostryukova, E. S., et al. (2017) · Bulletin of Experimental Biology and Medicine · doi:10.1007/s10517-017-3700-7 · Cited by 487 · see citing works

Altered gut microbiota and inflammatory cytokine responses in patients with Parkinson's disease

Lin, C.-H., Chen, C.-C., Chiang, H.-L., Liou, J.-M., Chang, C.-M., Lu, T.-P., Chuang, E. Y., Tai, Y.-C., Cheng, C., Lin, H.-Y., et al. (2019) · Journal of Neuroinflammation · doi:10.1186/s12974-019-1528-y · Cited by 469 · see citing works

Vagotomy and Parkinson disease: A Swedish register–based matched-cohort study

Liu, B., Fang, F., Pedersen, N. L., Tillander, A., Ludvigsson, J. F., Ekbom, A., Svenningsson, P., Chen, H., & Wirdefeldt, K. (2017) · Neurology · doi:10.1212/wnl.0000000000003961 · Cited by 447 · see citing works

Alteration of the fecal microbiota in Chinese patients with Parkinson’s disease

Qian, Y., Yang, X., Xu, S., Wu, C., Song, Y., Qin, N., Chen, S.-D., & Xiao, Q. (2018) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2018.02.016 · Cited by 409 · see citing works

Structural changes of gut microbiota in Parkinson's disease and its correlation with clinical features

Li, W., Wu, X., Hu, X., Wang, T., Liang, S., Duan, Y., Jin, F., & Qin, B. (2017) · Science China Life Sciences · doi:10.1007/s11427-016-9001-4 · Cited by 406 · see citing works

Computer Programs for Hierarchical Polythetic Classification ("Similarity Analyses")

Lance, G. N., & Williams, W. T. (1966) · The Computer Journal · doi:10.1093/comjnl/9.1.60 · Cited by 401 · see citing works

The Scientific Basis for Probiotic Strains ofLactobacillus

Reid, G. (1999) · Applied and Environmental Microbiology · doi:10.1128/aem.65.9.3763-3766.1999 · Cited by 399 · see citing works

Unraveling gut microbiota in Parkinson's disease and atypical parkinsonism

Barichella, M., Severgnini, M., Cilia, R., Cassani, E., Bolliri, C., Caronni, S., Ferri, V., Cancello, R., Ceccarani, C., Faierman, S., et al. (2019) · Movement Disorders · doi:10.1002/mds.27581 · Cited by 393 · see citing works

Probiotics and prebiotic fiber for constipation associated with Parkinson disease: An RCT

Barichella, M., Pacchetti, C., Bolliri, C., Cassani, E., Iorio, L., Pusani, C., Pinelli, G., Privitera, G., Cesari, I., Faierman, S. A., et al. (2016) · Neurology · doi:10.1212/wnl.0000000000003127 · Cited by 390 · see citing works

DECIPHER: harnessing local sequence context to improve protein multiple sequence alignment

Wright, E. S. (2015) · BMC Bioinformatics · doi:10.1186/s12859-015-0749-z · Cited by 388 · see citing works

Intestinal Microbiota Distinguish Gout Patients from Healthy Humans

Guo, Z., Zhang, J., Wang, Z., Ang, K. Y., Huang, S. W., Hou, Q., Su, X., Qiao, J., Zheng, Y., Wang, L., et al. (2016) · Scientific Reports · doi:10.1038/srep20602 · Cited by 381 · see citing works

A comparison of clinical and pathological features of young‐ and old‐onset Parkinson's disease

Gibb, W. R. G., & Lees, A. J. (1988) · Neurology · doi:10.1212/wnl.38.9.1402 · Cited by 371 · see citing works

Gut microbiota in Parkinson's disease: Temporal stability and relations to disease progression

Aho, V. T. E., Pereira, P. A. B., Voutilainen, S., Paulin, L., Pekkonen, E., Auvinen, P., & Scheperjans, F. (2019) · eBioMedicine · doi:10.1016/j.ebiom.2019.05.064 · Cited by 361 · see citing works

Gut microbiota in Parkinson disease in a northern German cohort

Hopfner, F., Künstner, A., Müller, S. H., Künzel, S., Zeuner, K. E., Margraf, N. G., Deuschl, G., Baines, J. F., & Kuhlenbäumer, G. (2017) · Brain Research · doi:10.1016/j.brainres.2017.04.019 · Cited by 318 · see citing works

In-vivo staging of pathology in REM sleep behaviour disorder: A multimodality imaging case-control study

Knudsen, K., Fedorova, T. D., Hansen, A. K., Sommerauer, M., Otto, M., Svendsen, K. B., Nahimi, A., Stokholm, M. G., Pavese, N., Beier, C. P., et al. (2018) · The Lancet Neurology · doi:10.1016/s1474-4422(18)30162-5 · Cited by 309 · see citing works

Changes of colonic bacterial composition in Parkinson's disease and other neurodegenerative diseases

Gerhardt, S., & Mohajeri, M. H. (2018) · Nutrients · doi:10.3390/nu10060708 · Cited by 298 · see citing works

A Role for Neuronal Alpha-Synuclein in Gastrointestinal Immunity

Stolzenberg, E. D., Berry, D. L., Yang, D., Lee, E. Y., Kroemer, A., Kaufman, S. S., Wong, G. C. L., Oppenheim, J. J., Sen, S., Fishbein, T., et al. (2017) · Journal of Innate Immunity · doi:10.1159/000477990 · Cited by 285 · see citing works

Gut Microbiota Mediates the Protective Effects of Dietary Capsaicin against Chronic Low-Grade Inflammation and Associated Obesity Induced by High-Fat Diet

Kang, C., Wang, B., Kaliannan, K., Wang, X., Lang, H., Hui, S., Huang, L., Zhang, Y., Zhou, M., Chen, M., et al. (2017) · mBio · doi:10.1128/mbio.00470-17 · Cited by 273 · see citing works

Gut microbiota in patients with Parkinson's disease in southern China

Lin, A., Zheng, W., He, Y., Tang, W., Wei, X., He, R., Huang, W., Su, Y., Huang, Y., Zhou, H., et al. (2018) · Parkinsonism &amp; Related Disorders · doi:10.1016/j.parkreldis.2018.05.007 · Cited by 253 · see citing works

Impacts of microbiome metabolites on immune regulation and autoimmunity

Haase, S., Haghikia, A., Wilck, N., Müller, D. N., & Linker, R. A. (2018) · Immunology · doi:10.1111/imm.12933 · Cited by 239 · see citing works

Genome-Wide Gene-Environment Study Identifies Glutamate Receptor Gene GRIN2A as a Parkinson's Disease Modifier Gene via Interaction with Coffee

Hamza, T. H., Chen, H., Hill-Burns, E. M., Rhodes, S. L., Montimurro, J., Kay, D. M., Tenesa, A., Kusel, V. I., Sheehan, P., Eaaswarkhanth, M., et al. (2011) · PLoS Genetics · doi:10.1371/journal.pgen.1002237 · Cited by 218 · see citing works

Dysbiosis of gut microbiota in a selected population of Parkinson's patients

Pietrucci, D., Cerroni, R., Unida, V., Farcomeni, A., Pierantozzi, M., Mercuri, N. B., Biocca, S., Stefani, A., & Desideri, A. (2019) · Parkinsonism &amp; Related Disorders · doi:10.1016/j.parkreldis.2019.06.003 · Cited by 217 · see citing works

Meta-analyses on prevalence of selected Parkinson's nonmotor symptoms before and after diagnosis

Chen, H., Zhao, E. J., Zhang, W., Lu, Y., Liu, R., Huang, X., Ciesielski-Jones, A. J., Justice, M. A., Cousins, D. S., & Peddada, S. (2015) · Translational Neurodegeneration · doi:10.1186/2047-9158-4-1 · Cited by 212 · see citing works

Stool Immune Profiles Evince Gastrointestinal Inflammation in Parkinson's Disease

Houser, M. C., Chang, J., Factor, S. A., Molho, E., Zabetian, C. P., Hill‐Burns, E. M., Payami, H., Hertzberg, V., & Tansey, M. G. (2018) · Movement Disorders · doi:10.1002/mds.27326 · Cited by 200 · see citing works

Bidirectional regulatory potentials of short-chain fatty acids and their G-protein-coupled receptors in autoimmune neuroinflammation

Park, J., Wang, Q., Wu, Q., Mao‐Draayer, Y., & Kim, C. H. (2019) · Scientific Reports · doi:10.1038/s41598-019-45311-y · Cited by 197 · see citing works

Gut–brain axis and the spread of α‐synuclein pathology: Vagal highway or dead end?

Breen, D. P., Halliday, G. M., & Lang, A. E. (2019) · Movement Disorders · doi:10.1002/mds.27556 · Cited by 193 · see citing works

Gene–environment interactions in Parkinson's disease: Specific evidence in humans and mammalian models

Cannon, J. R., & Greenamyre, J. T. (2012) · Neurobiology of Disease · doi:10.1016/j.nbd.2012.06.025 · Cited by 191 · see citing works

Bacterial community collapse: a meta‐analysis of the sinonasal microbiota in chronic rhinosinusitis

Mackenzie, B. W., Waite, D. W., Hoggard, M., Douglas, R. G., Taylor, M. W., & Biswas, K. (2016) · Environmental Microbiology · doi:10.1111/1462-2920.13632 · Cited by 181 · see citing works

Gut Microbiota Differs Between Parkinson’s Disease Patients and Healthy Controls in Northeast China

Li, C., Cui, L., Yang, Y., Miao, J., Zhao, X., Zhang, J., Cui, G., & Zhang, Y. (2019) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2019.00171 · Cited by 178 · see citing works

Increasing Comparability and Utility of Gut Microbiome Studies in Parkinson’s Disease: A Systematic Review

Boertien, J. M., Pereira, P. A. B., Aho, V. T. E., & Scheperjans, F. (2019) · Journal of Parkinson s Disease · doi:10.3233/jpd-191711 · Cited by 169 · see citing works

Starke Belege: Parkinson könnte im Verdauungstrakt beginnen

(2017) · Fortschritte der Neurologie · Psychiatrie · doi:10.1055/s-0043-113319 · Cited by 162 · see citing works

Effect of Parkinson’s Disease and Related Medications on the Composition of the Fecal Bacterial Microbiota

Weis, S., Schwiertz, A., Unger, M. M., Becker, A., Faßbender, K., Ratering, S., Kohl, M., Schnell, S., Schäfer, K.-H., & Egert, M. (2019) · npj Parkinson s Disease · doi:10.1038/s41531-019-0100-x · Cited by 145 · see citing works

Combined effects of smoking, coffee, and NSAIDs on Parkinson's disease risk

Powers, K. M., Kay, D. M., Factor, S. A., Zabetian, C. P., Higgins, D. S., Samii, A., Nutt, J. G., Griffith, A., Leis, B. C., Roberts, J. W., et al. (2007) · Movement Disorders · doi:10.1002/mds.21782 · Cited by 144 · see citing works

Alterations in fecal short-chain fatty acids in patients with irritable bowel syndrome

Sun, Q., Jia, Q., Song, L., & Duan, L. (2019) · Medicine · doi:10.1097/md.0000000000014513 · Cited by 141 · see citing works

Lactobacillus: Host–Microbe Relationships

O’Callaghan, J., & O’Toole, P. W. (2011) · Current topics in microbiology and immunology · doi:10.1007/82_2011_187 · Cited by 135 · see citing works

Alteration of the fecal microbiota in North-Eastern Han Chinese population with sporadic Parkinson’s disease

Li, F., Wang, P., Chen, Z., Sui, X., Xie, X., & Zhang, J. (2019) · Neuroscience Letters · doi:10.1016/j.neulet.2019.134297 · Cited by 97 · see citing works

Rapid and Sustained Long‐Term Decrease of Fecal Short‐Chain Fatty Acids in Critically Ill Patients With Systemic Inflammatory Response Syndrome

Yamada, T., Shimizu, K., Ogura, H., Asahara, T., Nomoto, K., Yamakawa, K., Hamasaki, T., Nakahori, Y., Ohnishi, M., Kuwagata, Y., et al. (2014) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607114529596 · Cited by 93 · see citing works

Advances in environmental epidemiology

Tanner, C. M. (2010) · Movement Disorders · doi:10.1002/mds.22721 · Cited by 92 · see citing works

A genetic basis for the variable effect of smoking/nicotine on Parkinson’s disease

Hill-Burns, E. M., Singh, N., Ganguly, P., Hamza, T. H., Montimurro, J. S., Kay, D. M., Yearout, D., Sheehan, P., Frodey, K., McLear, J. A., et al. (2012) · The Pharmacogenomics Journal · doi:10.1038/tpj.2012.38 · Cited by 69 · see citing works

Holocranohistochemistry enables the visualization of α-synuclein expression in the murine olfactory system and discovery of its systemic anti-microbial effects

Tomlinson, J. J., Shutinoski, B., Dong, L. M., Meng, F., Elleithy, D., Lengacher, N. A., Nguyen, A., Cron, G. O., Jiang, Q., Roberson, E. D., et al. (2017) · Journal of Neural Transmission · doi:10.1007/s00702-017-1726-7 · Cited by 63 · see citing works

Tyrosine decarboxylase from Lactobacillus brevis: Soluble expression and characterization

Zhang, K., & Ni, Y. (2013) · Protein Expression and Purification · doi:10.1016/j.pep.2013.10.018 · Cited by 61 · see citing works

Co-occurrence of Anaerobes in Human Chronic Wounds

Choi, Y., Banerjee, A., McNish, S., Couch, K. S., Torralba, M., Lucas, S. K., Tovchigrechko, A., Madupu, R., Yooseph, S., Nelson, K. E., et al. (2018) · Microbial Ecology · doi:10.1007/s00248-018-1231-z · Cited by 55 · see citing works

Genome-wide gene-environment interaction analysis of pesticide exposure and risk of Parkinson's disease

Biernacka, J. M., Chung, S. J., Armasu, S. M., Anderson, K. S., Lill, C. M., Bertram, L., Ahlskog, J. E., Brighina, L., Frigerio, R., & Maraganore, D. M. (2016) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2016.08.002 · Cited by 41 · see citing works

Erratum to: Functional implications of microbial and viral gut metagenome changes in early stage L-DOPA-naive Parkinson's disease patients (vol 9, pg 39, 2017)

Bedarf, J. R., Hildebrand, F., Coelho, L. P., Sunagawa, S., Bahram, M., Goeser, F., Peer Bork, B., & Wüllner, U. (2017) · Repository for Publications and Research Data (ETH Zurich) · doi:10.3929/ethz-b-000191807 · Cited by 13 · see citing works

The microbiome–gut–brain axis in Parkinson disease — from basic research to the clinic

Tan, A. H., Lim, S. Y., & Lang, A. E. (2022) · Nature Reviews Neurology · doi:10.1038/s41582-022-00681-2 · Cited by 392 · see citing works

Metagenomics of Parkinson’s disease implicates the gut microbiome in multiple disease mechanisms

Wallen, Z. D., Demirkan, A., Twa, G., Cohen, G., Dean, M. N., Standaert, D. G., Sampson, T. R., & Payami, H. (2022) · Nature Communications · doi:10.1038/s41467-022-34667-x · Cited by 346 · see citing works

The role of gut dysbiosis in Parkinson’s disease: mechanistic insights and therapeutic options

Wang, Q., Luo, Y., Ray Chaudhuri, K., Reynolds, R., Tan, E.-K., & Pettersson, S. (2021) · Brain · doi:10.1093/brain/awab156 · Cited by 281 · see citing works

Desulfovibrio Bacteria Are Associated With Parkinson’s Disease

Murros, K. E., Huynh, V. A., Takala, T. M., & Saris, P. E. J. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2021.652617 · Cited by 218 · see citing works

The Association Between the Gut Microbiota and Parkinson’s Disease, a Meta-Analysis

Shen, T., Yue, Y., He, T., Huang, C., Qu, B., Lv, W., & Lai, H.-Y. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.636545 · Cited by 219 · see citing works

Parkinson’s Disease and Gut Microbiota

Hirayama, M., & Ohno, K. (2021) · Annals of Nutrition and Metabolism · doi:10.1159/000518147 · Cited by 158 · see citing works

Probiotics synergized with conventional regimen in managing Parkinson’s disease

Sun, H., Zhao, F., Liu, Y., Ma, T., Jin, H., Quan, K., Leng, B., Zhao, J., Yuan, X., Li, Z., et al. (2022) · npj Parkinson's Disease · doi:10.1038/s41531-022-00327-6 · Cited by 136 · see citing works

Potential roles of gut microbiota and microbial metabolites in Parkinson’s disease

Zheng, S.-Y., Li, H.-X., Xu, R.-C., Miao, W.-T., Dai, M.-Y., Ding, S.-T., & Liu, H.-D. (2021) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101347 · Cited by 101 · see citing works

Oral and Gut Dysbiosis Leads to Functional Alterations in Parkinson’s Disease

Jo, S., Kang, W., Hwang, Y. S., Lee, S. H., Park, K. W., Kim, M. S., Lee, H., Yoon, H. J., Park, Y. K., Chalita, M., et al. (2022) · npj Parkinson s Disease · doi:10.1038/s41531-022-00351-6 · Cited by 85 · see citing works

The Interplay between Gut Microbiota and Parkinson’s Disease: Implications on Diagnosis and Treatment

Varesi, A., Campagnoli, L. I. M., Fahmideh, F., Pierella, E., Romeo, M., Ricevuti, G., Nicoletta, M., Chirumbolo, S., & Pascale, A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232012289 · Cited by 88 · see citing works

New avenues for Parkinson's disease therapeutics: disease-modifying strategies based on the gut microbiota

Lorente-Picón, M., & Laguna, A. (2021) · Biomolecules · doi:10.3390/biom11030433 · Cited by 69 · see citing works

The Gut Microbiome in Parkinson’s Disease: A Longitudinal Study of the Impacts on Disease Progression and the Use of Device-Assisted Therapies

Lubomski, M., Xu, X., Holmes, A. J., Muller, S., Yang, J. Y. H., Davis, R. L., & Sue, C. M. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.875261 · Cited by 59 · see citing works

Shorter sleep time relates to lower human defensin 5 secretion and compositional disturbance of the intestinal microbiota accompanied by decreased short-chain fatty acid production

Shimizu, Y., Yamamura, R., Yokoi, Y., Ayabe, T., Ukawa, S., Nakamura, K., Okada, E., Imae, A., Nakagawa, T., Tamakoshi, A., et al. (2023) · Gut Microbes · doi:10.1080/19490976.2023.2190306 · Cited by 53 · see citing works

Exploring Human-Genome Gut-Microbiome Interaction in Parkinson’s Disease

Wallen, Z. D., Stone, W. J., Factor, S. A., Molho, E., Zabetian, C. P., Standaert, D. G., & Payami, H. (2021) · npj Parkinson s Disease · doi:10.1038/s41531-021-00218-2 · Cited by 41 · see citing works

Toward a health-associated core keystone index for the human gut microbiome

Goel, A., Shete, O., Goswami, S., Samal, A., C.B., L., Kedia, S., Ahuja, V., O’Toole, P. W., Shanahan, F., & Ghosh, T. S. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.115378 · Cited by 37 · see citing works

Molecular Communication Between Neuronal Networks and Intestinal Epithelial Cells in Gut Inflammation and Parkinson’s Disease

Drobny, A., Ngo, P. A., Neurath, M. F., Zunke, F., & López-Posadas, R. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.655123 · Cited by 24 · see citing works

Concordance with Medication and Older People

Banning, M. (2007) · doi:10.1002/9780470692264.ch6

The Promise and Limits of Racial/Ethnic Concordance in Physician-Patient Interaction

Schnittker, J., & Ke, L. (2006) · Journal of Health Politics Policy and Law · doi:10.1215/03616878-2006-004 · Cited by 55 · see citing works

Parental non-concordance with occlusion therapy

Newsham, D. (2000) · British Journal of Ophthalmology · doi:10.1136/bjo.84.9.957 · Cited by 103 · see citing works

A concordance to King Horn ; a concordance to Athelston ; a concordance to Gamelyn

斎藤, 俊., 今井, 光., & Miki, K. (1986) · Faculty of Language and Culture, Osaka university eBooks

Concordance for Parkinson's disease in twins: A 20‐year update

Goldman, S. M., MAREK, K. L., Ottman, R., Meng, C., Comyns, K., Chan, P., Ma, J., Marras, C., Langston, J. W., Ross, G. W., et al. (2019) · Annals of Neurology · doi:10.1002/ana.25441 · Cited by 114 · see citing works