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Microglial depletion prevents extracellular matrix changes and striatal volume reduction in a model of Huntington's disease

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AMPA Receptors as Therapeutic Targets for Neurological Disorders

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Genes and the Environment in Neurodegeneration

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Striatal synaptic dysfunction and altered calcium regulation in Huntington disease

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Alterations in N-methyl-D-aspartate receptor sensitivity and magnesium blockade occur early in development in the R6/2 mouse model of Huntington's disease

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Decreased N-methyl-d-aspartic acid (NMDA) receptor levels are associated with mercury exposure in wild and captive mink

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A Large Number of Protein Expression Changes Occur Early in Life and Precede Phenotype Onset in a Mouse Model for Huntington Disease

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Hippo Signaling Pathway Dysregulation in Human Huntington’s Disease Brain and Neuronal Stem Cells

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Altered cortical glutamate receptor function in the R6/2 model of Huntington's disease.

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Dopamine-dependent long term potentiation in the dorsal striatum is reduced in the R6/2 mouse model of Huntington’s disease

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Enviromimetics: exploring gene environment interactions to identify therapeutic targets for brain disorders

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Behavioral and electrophysiological effects of the adenosine A2A receptor antagonist SCH 58261 in R6/2 Huntington’s disease mice

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The R6 lines of transgenic mice: A model for screening new therapies for Huntington's disease

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Integrated analysis of genetic, genomic and proteomic data

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GENE–ENVIRONMENT INTERACTIONS, NEURONAL DYSFUNCTION AND PATHOLOGICAL PLASTICITY IN HUNTINGTON'S DISEASE

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Synaptopathic mechanisms of neurodegeneration and dementia: Insights from Huntington’s disease

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Absence of aryl hydrocarbon receptors increases endogenous kynurenic acid levels and protects mouse brain against excitotoxic insult and oxidative stress

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Transcranial Low-Intensity Pulsed Ultrasound Modulates Structural and Functional Synaptic Plasticity in Rat Hippocampus

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Regional and subtype selective changes of neurotransmitter receptor density in a rat transgenic for the Huntington's disease mutation

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Genetic rescue of CB1 receptors on medium spiny neurons prevents loss of excitatory striatal synapses but not motor impairment in HD mice

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Polyglutamine gene function and dysfunction in the ageing brain

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MAGUK proteins: New targets for pharmacological intervention in the glutamatergic synapse

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Glutamate receptor abnormalities in the YAC128 transgenic mouse model of Huntington’s disease

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Epigenetic Mechanisms Involved in Huntington's Disease Pathogenesis

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2,4 DNP improves motor function, preserves medium spiny neuronal identity, and reduces oxidative stress in a mouse model of Huntington's disease

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Upcoming Meetings Related to Huntington's Disease

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Phosphodiesterases: Regulators of cyclic nucleotide signals and novel molecular target for movement disorders

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Changes in Expression of N-Methyl-D-Aspartate Receptor Subunits Occur Early in the R6/2 Mouse Model of Huntington’s Disease

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Induced pluripotent stem cell lines from Huntington's disease mice undergo neuronal differentiation while showing alterations in the lysosomal pathway

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Accelerators, Brakes, and Gears of Actin Dynamics in Dendritic Spines

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Dysfunction of the Ubiquitin Ligase Ube3a May Be Associated with Synaptic Pathophysiology in a Mouse Model of Huntington Disease

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Trafficking and Targeting of NMDA Receptors

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Protective up‐regulation of CK2 by mutant huntingtin in cells co‐expressing NMDA receptors

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Striatal Synaptosomes from Hdh140Q/140Q Knock-in Mice have Altered Protein Levels, Novel Sites of Methionine Oxidation, and Excess Glutamate Release after Stimulation

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Prostaglandin E2 EP1 Receptor Antagonist Improves Motor Deficits and Rescues Memory Decline in R6/1 Mouse Model of Huntington's Disease

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The Functional and Molecular Properties, Physiological Functions, and Pathophysiological Roles of GluN2A in the Central Nervous System

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Altered Sensory Experience Exacerbates Stable Dendritic Spine and Synapse Loss in a Mouse Model of Huntington's Disease

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Modulation of NMDA receptor at the synapse: Promising therapeutic interventions in disorders of the nervous system

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Disruption of zinc transporter ZnT3 transcriptional activity and synaptic vesicular zinc in the brain of Huntington’s disease transgenic mouse

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Novel therapeutic targets for Huntington’s disease

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Diminished Activity-Dependent Brain-Derived Neurotrophic Factor Expression Underlies Cortical Neuron Microcircuit Hypoconnectivity Resulting from Exposure to Mutant Huntingtin Fragments

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Emerging chemotherapeutic strategies for Huntington’s disease

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Plastic abnormalities in experimental Huntington's disease

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Molecular mechanisms mediating pathological plasticity in Huntington's disease and Alzheimer's disease

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Remodeling of striatal NMDA receptors by chronic A2A receptor blockade in Huntington's disease mice

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Cdk5 Contributes to Huntington’s Disease Learning and Memory Deficits via Modulation of Brain Region-Specific Substrates

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Modified Glutamatergic Postsynapse in Neurodegenerative Disorders

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Expression, pharmacology and functional activity of adenosine A1 receptors in genetic models of Huntington's disease

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Transcriptional Regulation of NMDA Receptor Expression

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Overview of Huntington's Disease Models: Neuropathological, Molecular, and Behavioral Differences

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Identify Huntington’s disease associated genes based on restricted Boltzmann machine with RNA-seq data

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Influence of CGS 21680, a selective adenosine A2A receptor agonist, on NMDA receptor function and expression in the brain of Huntington's disease mice

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Functional interactions within striatal microcircuit in animal models of Huntington's disease

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Polyglutamine Disorders Including Huntington's Disease

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Age‐dependent gene expression profile and protein expression in a transgenic rat model of Huntington's disease

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HSF1 and Its Role in Huntington’s Disease Pathology

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Detailed evaluation of protein adsorption on alumina surface through surface plasmon resonance phenomenon

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Evaluation of protein adsorption on hydrogenated amorphous carbon films by surface plasmon resonance phenomenon

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Selection of Behaviors and Segmental Coordination During Larval Locomotion Is Disrupted by Nuclear Polyglutamine Inclusions in a NewDrosophilaHuntington's Disease–Like Model

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Excitotoxicity, Oxidative Stress, and Neuronal Injury

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Glutamate receptor pathology is present in the hippocampus following repeated sub-lethal soman exposure in the absence of spatial memory deficits

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Physiopathologie de la maladie de Huntington : état des connaissances

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mGluR5 ablation leads to age-related synaptic plasticity impairments and does not improve Huntington’s disease phenotype

de Souza, J. M., Ferreira-Vieira, T. H., Maciel, E. M. A., Silva, N. C., de Lima, I. B. Q., Doria, J. G., Olmo, I. G., & Ribeiro, F. M. (2022) · Scientific Reports · doi:10.1038/s41598-022-13029-z · Cited by 8 · see citing works

Ensemble Consensus-Guided Unsupervised Feature Selection to Identify Huntington’s Disease-Associated Genes

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Synaptic Abnormalities Associated with Huntington’s Disease

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Molecular Properties and Cell Biology of the NMDA Receptor

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Restoring endogenous Dlg4/PSD95 expression by an artificial transcription factor ameliorates cognitive and motor learning deficits in the R6/2 mouse model of Huntington’s disease

Fernández, G. R., Leiva, K., Bustos, F. J., & van Zundert, B. (2025) · Clinical Epigenetics · doi:10.1186/s13148-025-01903-2 · Cited by 3 · see citing works

Ataxin-2 Binds Alpha-Actinin-1Preprint

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Alterations in Expression and Function of Phosphodiesterases in Huntington’s Disease

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Pathogenesis of Huntington’s Disease: How to Fight Excitotoxicity and Transcriptional Dysregulation

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Biological properties of α-actinin-2 and its role and mechanisms in disease development

Meng, J., Xu, S.-Q., Qi, D. E. N. G., Jiang, L., Huang, D.-P., Wang, Q.-S., & Wu, Y.-K. (2026) · Frontiers in Physiology · doi:10.3389/fphys.2026.1794324 · Cited by 1 · see citing works

Identification of disease-related genes based on tensor factorization with RNA-seq data of huntington's disease mice

Jiang, X. (2017) · Chinese Automation Congress · doi:10.1109/cac.2017.8242731 · Cited by 1 · see citing works

Accelerators, Brakes, and Gears of Actin Dynamics in Dendritic Spines

Pontrello, C. G., & Ethell, I. M. (2014) · The Open Neuroscience Journal · doi:10.2174/1874082000903010067 · Cited by 1 · see citing works

Finding diamonds in the rubble

CHA, J. (2007) · Experimental Neurology · doi:10.1016/j.expneurol.2007.02.003 · Cited by 1 · see citing works

A study of depression in Huntington's disease

Pang, T. Y. (2008) · Minerva Access (University of Melbourne)

Mutant huntingtin reduces vesicular zinc level by inhibiting the binding of Sp1 to ZnT3 promoterPreprint

Niu, L., Yang, S., Wang, W., Ye, C., & Li, H. (2020) · Research Square · doi:10.21203/rs.3.rs-29099/v1

Disruption of zinc transporter ZnT3 transcriptional activity and synaptic vesicular zinc in the brain of Huntington’s disease transgenic mousePreprint

Niu, L., Yang, S., Wang, W., Ye, C., & Li, H. (2022) · Research Square · doi:10.21203/rs.3.rs-29099/v2

Fingolimod Effects on Motor Function and BDNF-TrkB Signaling in a Huntington’s Mouse Model Are Disease-Stage-Dependent

Nguyen, K. Q., Rymar, V. V., & Sadikot, A. F. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27010494

Changes in Expression of N-Methyl-D-Aspartate Receptor Subunits Occur Early in the R6/2 Mouse Model of Huntington’s Disease

Ali, N. J., & Levine, M. S. (2006) · Developmental Neuroscience · doi:10.1159/000091921 · Cited by 44 · see citing works

Altered NMDA Receptor Trafficking in a Yeast Artificial Chromosome Transgenic Mouse Model of Huntington's Disease

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Mechanisms of modulation of N-methyl-D-aspartate (NMDA) receptors by mutant huntingtin

Fan, M. (2011) · cIRcle (University of British Columbia) · doi:10.14288/1.0100374

Subtype‐Specific Enhancement of NMDA Receptor Currents by Mutant Huntingtin

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Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human Huntington disease gene

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