Schnabl, Bernd

The gut-liver axis and the intersection with the microbiome

Tripathi, A., Debelius, J., Brenner, D. A., Karin, M., Loomba, R., Schnabl, B., & Knight, R. (2018) · Nature Reviews Gastroenterology & Hepatology

Gut microbiota and healthLiver Disease Diagnosis and Treatment

Cited by 1,480

Adenoma–linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth

Grivennikov, S. I., Wang, K., Mucida, D., Stewart, C. A., Schnabl, B., Jauch, D., Taniguchi, K., Yu, G.-Y., Österreicher, C. H., Hung, K. E., et al. (2012) · Nature

Cancer Immunotherapy and BiomarkersIL-33, ST2, and ILC Pathways

Cited by 1,327

New mitochondrial DNA synthesis enables NLRP3 inflammasome activation

Zhong, Z., Liang, S., Sanchez-Lopez, E., He, F., Shalapour, S., Lin, X.-J., Wong, J., Ding, S., Seki, E., Schnabl, B., et al. (2018) · Nature

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 1,208

Gut Microbiome-Based Metagenomic Signature for Non-invasive Detection of Advanced Fibrosis in Human Nonalcoholic Fatty Liver Disease

Loomba, R., Seguritan, V., Li, W., Long, T., Klitgord, N., Bhatt, A., Dulai, P. S., Caussy, C., Bettencourt, R., Highlander, S. K., et al. (2017) · Cell Metabolism

Gut microbiota and healthLiver Disease Diagnosis and Treatment

Cited by 1,123

Interactions Between the Intestinal Microbiome and Liver Diseases

Schnabl, B., & Brenner, D. A. (2014) · Gastroenterology

Gut microbiota and healthLiver Disease Diagnosis and Treatment

Cited by 971

Bacterial infections in cirrhosis: A position statement based on the EASL Special Conference 2013

Jalan, R., Fernandez, J., Wiest, R., Schnabl, B., Moreau, R., Angeli, P., Stadlbauer, V., Gustot, T., Bernardi, M., Canton, R., et al. (2014) · Journal of Hepatology

Liver Disease and TransplantationSepsis Diagnosis and Treatment

Cited by 906

Enteric dysbiosis associated with a mouse model of alcoholic liver disease

Yan, A. W., Fouts, D. E., Brandl, J., Stärkel, P., Torralba, M., Schott, E., Tsukamoto, H., Nelson, K. E., Brenner, D. A., & Schnabl, B. (2011) · Hepatology

Gut microbiota and healthAlcohol Consumption and Health Effects

Cited by 791

Toll-Like Receptor 9 Promotes Steatohepatitis by Induction of Interleukin-1β in Mice

Miura, K., Kodama, Y., Inokuchi, S., Schnabl, B., Aoyama, T., Ohnishi, H., Olefsky, J. M., Brenner, D. A., & Seki, E. (2010) · Gastroenterology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 741

Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance

Fang, S., Suh, J. M., Reilly, S. M., Yu, E., Osborn, O., Lackey, D., Yoshihara, E., Perino, A., Jacinto, S., Lukasheva, Y., et al. (2015) · Nature Medicine

Adipose Tissue and MetabolismDrug Transport and Resistance Mechanisms

Cited by 738

The gut–liver axis and gut microbiota in health and liver disease

Hsu, C. L., & Schnabl, B. (2023) · Nature Reviews Microbiology

Gut microbiota and healthLiver Disease and Transplantation

Cited by 737

Vancomycin-resistant enterococci exploit antibiotic-induced innate immune deficits

Brandl, K., Plitas, G., Mihu, C. N., Ubeda, C., Jia, T., Fleisher, M., Schnabl, B., DeMatteo, R. P., & Pamer, E. G. (2008) · Nature

Gut microbiota and healthAntibiotic Resistance in Bacteria

Cited by 631

Gut microbiome, liver immunology, and liver diseases

Wang, R., Tang, R., Li, B., Ma, X., Schnabl, B., & Tilg, H. (2021) · Cellular & Molecular Immunology

Gut microbiota and healthLiver Diseases and Immunity

Cited by 466

Small metabolites, possible big changes: A microbiota-centered view of non-alcoholic fatty liver disease

Chu, H., Duan, Y., Yang, L., & Schnabl, B. (2019) · Gut

Gut microbiota and healthLiver Disease Diagnosis and Treatment

Cited by 354

Supplementation of Saturated Long-Chain Fatty Acids Maintains Intestinal Eubiosis and Reduces Ethanol-induced Liver Injury in Mice

Chen, P., Torralba, M., Tan, J., Embree, M., Zengler, K., Stärkel, P., van Pijkeren, J.-P., DePew, J., Loomba, R., Ho, S. B., et al. (2015) · Gastroenterology

Gut microbiota and healthAlcohol Consumption and Health Effects

Cited by 322

Dysbiosis‐induced intestinal inflammation activates tumor necrosis factor receptor I and mediates alcoholic liver disease in mice

Chen, P., Stärkel, P., Turner, J. R., Ho, S. B., & Schnabl, B. (2015) · Hepatology

Alcohol Consumption and Health EffectsGut microbiota and health

Cited by 312

Bacterial translocation and changes in the intestinal microbiome in mouse models of liver disease

Fouts, D. E., Torralba, M., Nelson, K. E., Brenner, D. A., & Schnabl, B. (2012) · Journal of Hepatology

Gut microbiota and healthLiver Disease and Transplantation

Cited by 311

Modulation of the intestinal bile acid/farnesoid X receptor/fibroblast growth factor 15 axis improves alcoholic liver disease in mice

Hartmann, P., Hochrath, K., Horvath, A., Chen, P., Seebauer, C. T., Llorente, C., Wang, L., Alnouti, Y., Fouts, D. E., Stärkel, P., et al. (2018) · Hepatology

Gut microbiota and healthAlcohol Consumption and Health Effects

Cited by 290

Hepatitis C virus–induced oxidative stress suppresses hepcidin expression through increased histone deacetylase activity

Miura, K., Taura, K., Kodama, Y., Schnabl, B., & Brenner, D. A. (2008) · Hepatology

Iron Metabolism and DisordersHepatitis C virus research

Cited by 270

Gastric acid suppression promotes alcoholic liver disease by inducing overgrowth of intestinal Enterococcus

Llorente, C., Jepsen, P., Inamine, T., Wang, L., Bluemel, S., Wang, H. J., Loomba, R., Bajaj, J. S., Schubert, M. L., Sikaroodi, M., et al. (2017) · Nature Communications

Gut microbiota and healthAlcohol Consumption and Health Effects

Cited by 257

Methods to determine intestinal permeability and bacterial translocation during liver disease

Wang, L., Llorente, C., Hartmann, P., Yang, A.-M., Chen, P., & Schnabl, B. (2015) · Journal of Immunological Methods

Liver Disease and TransplantationGut microbiota and health

Cited by 257

Deficiency of intestinal mucin-2 ameliorates experimental alcoholic liver disease in mice

Hartmann, P., Chen, P., Wang, H. J., Wang, L., McCole, D. F., Brandl, K., Stärkel, P., Belzer, C., Hellerbrand, C., Tsukamoto, H., et al. (2013) · Hepatology

Alcohol Consumption and Health EffectsGut microbiota and health

Cited by 246

Pyroptosis by caspase11/4‐gasdermin‐D pathway in alcoholic hepatitis in mice and patients

Khanova, E., Wu, R., Wang, W., Yan, R., Chen, Y., French, S. W., Llorente, C., Pan, S. Q., Yang, Q., Li, Y., et al. (2018) · Hepatology

Inflammasome and immune disordersAlcohol Consumption and Health Effects

Cited by 228

Replicative Senescence of Activated Human Hepatic Stellate Cells Is Accompanied by A Pronounced Inflammatory But Less Fibrogenic Phenotype

Schnabl, B., Purbeck, C. A., Choi, Y. H., Hagedorn, C. H., & Brenner, D. (2003) · Hepatology

Liver physiology and pathologyTelomeres, Telomerase, and Senescence

Cited by 224

Link between gut‐microbiome derived metabolite and shared gene‐effects with hepatic steatosis and fibrosis in NAFLD

Caussy, C., Hsu, C., Lo, M., Liu, A., Bettencourt, R., Ajmera, V. H., Bassirian, S., Hooker, J., Sy, E., Richards, L., et al. (2018) · Hepatology

Liver Disease Diagnosis and TreatmentGut microbiota and health

Cited by 205