Lovestone, Simon

The EMIF-AD Multimodal Biomarker Discovery study: design, methods and cohort characteristics

Bos, I., Vos, S., Vandenberghe, R., Scheltens, P., Engelborghs, S., Frisoni, G., Molinuevo, J. L., Wallin, A., Lleó, A., Popp, J., et al. (2018) · Alzheimer's Research & Therapy

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 112

Plasma Based Markers of [11C] PiB-PET Brain Amyloid Burden

Kiddle, S. J., Thambisetty, M., Simmons, A., Riddoch-Contreras, J., Hye, A., Westman, E., Pike, I., Ward, M., Johnston, C., Lupton, M. K., et al. (2012) · PLoS ONE

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 100

Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders

study, T. A. I. B. A. L., Nabais, M. F., Initiative, T. A. D. N., Laws, S. M., Lin, T., Vallerga, C. L., Armstrong, N. J., Blair, I. P., Kwok, J. B., Mather, K. A., et al. (2021) · Genome Biology

Epigenetics and DNA MethylationDementia and Cognitive Impairment Research

Cited by 99

An epigenome-wide association study of Alzheimer's disease blood highlights robust DNA hypermethylation in the HOXB6 gene

Roubroeks, J. A. Y., Smith, A. R., Smith, R. G., Pishva, E., Ibrahim, Z., Sattlecker, M., Hannon, E. J., Kłoszewska, I., Mecocci, P., Soininen, H., et al. (2020) · Neurobiology of Aging

Epigenetics and DNA MethylationDementia and Cognitive Impairment Research

Cited by 82

MRI predictors of amyloid pathology: results from the EMIF-AD Multimodal Biomarker Discovery study

ten Kate, M., Redolfi, A., Peira, E., Bos, I., Vos, S. J., Vandenberghe, R., Gabel, S., Schaeverbeke, J., Scheltens, P., Blin, O., et al. (2018) · Alzheimer's Research & Therapy

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 78

The Antidepressant Clomipramine Regulates Cortisol Intracellular Concentrations and Glucocorticoid Receptor Expression in Fibroblasts and Rat Primary Neurones

Pariante, C. M., Hye, A., Williamson, R., Makoff, A., Lovestone, S., & Kerwin, R. W. (2003) · Neuropsychopharmacology

Stress Responses and CortisolTreatment of Major Depression

Cited by 70

Stability of graph theoretical measures in structural brain networks in Alzheimer’s disease

Mårtensson, G., Pereira, J. B., Mecocci, P., Vellas, B., Tsolaki, M., Kłoszewska, I., Soininen, H., Lovestone, S., Simmons, A., Volpe, G., et al. (2018) · Scientific Reports

Functional Brain Connectivity StudiesComplex Network Analysis Techniques

Cited by 60

Alzheimer's disease susceptibility variants in the MS4A6A gene are associated with altered levels of MS4A6A expression in blood

Proitsi, P., Lee, S. H., Lunnon, K., Keohane, A., Powell, J., Troakes, C., Al-Sarraj, S., Furney, S., Soininen, H., Kłoszewska, I., et al. (2014) · Neurobiology of Aging

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 57

Stimulation of MAP kinase by v‐raf transformation of fibroblasts fails to induce hyperphosphorylation of transfected tau

Latimer, D. A., Gallo, J.-M., Lovestone, S., Miller, C. C. J., Hugh Reynolds, C., Marquardt, B., Stabel, S., Woodgett, J. R., & Anderton, B. H. (1995) · FEBS Letters

Alzheimer's disease research and treatmentsProtein Kinase Regulation and GTPase Signaling

Cited by 48

Genome-Wide Association Study of Alzheimer’s Disease Brain Imaging Biomarkers and Neuropsychological Phenotypes in the European Medical Information Framework for Alzheimer’s Disease Multimodal Biomarker Discovery Dataset

Homann, J., Osburg, T., Ohlei, O., Dobricic, V., Deecke, L., Bos, I., Vandenberghe, R., Gabel, S., Scheltens, P., Teunissen, C. E., et al. (2022) · Frontiers in Aging Neuroscience

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 46

Urinary metabolic phenotyping for Alzheimer’s disease

Kurbatova, N., Garg, M., Whiley, L., Chekmeneva, E., Jiménez, B., Gómez-Romero, M., Pearce, J., Kimhofer, T., D’Hondt, E., Soininen, H., et al. (2020) · Scientific Reports

Metabolomics and Mass Spectrometry StudiesDementia and Cognitive Impairment Research

Cited by 44

Evaluating the Alzheimer’s disease data landscape

Birkenbihl, C., Salimi, Y., Domingo‐Fernándéz, D., Lovestone, S., AddNeuroMed consortium, Fröhlich, H., Hofmann‐Apitius, M., Initiative, T. J. A. D. N., & Initiative, A. T. A. D. N. (2020) · Alzheimer's & Dementia: Translational Research & Clinical Interventions

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 37

Meta-analysis of genetic association with diagnosed Alzheimer’s disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing

Kunkle, B., Grenier-Boley, B., Sims, R., Bis, J., Naj, A., Boland, A., Vronskaya, M., van der Lee, S., Amlie-Wolf, A., Bellenguez, C., et al. (2018) · bioRxiv (Cold Spring Harbor Laboratory)

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 35

Application of a MRI based index to longitudinal atrophy change in Alzheimer disease, mild cognitive impairment and healthy older individuals in the AddNeuroMed cohort

Aguilar, C., Muehlboeck, J.-S., Mecocci, P., Vellas, B., Tsolaki, M., Kloszewska, I., Soininen, H., Lovestone, S., Wahlund, L.-O., Simmons, A., et al. (2014) · Frontiers in Aging Neuroscience

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 34

A missense variant in SHARPIN mediates Alzheimer’s disease-specific brain damages

Park, J. Y., Lee, D., Lee, J. J., Gim, J., Gunasekaran, T. I., Choi, K. Y., Kang, S., Do, A. R., Jo, J., Park, J., et al. (2021) · Translational Psychiatry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 21

Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH

Killick, R., Hughes, T. R., Morgan, B. P., & Lovestone, S. (2013) · Neuroscience Letters

Alzheimer's disease research and treatmentsComplement system in diseases

Cited by 17

Pharmacological modulation of TSPO in microglia/macrophages and neurons in a chronic neurodegenerative model of prion disease

Vicente-Rodríguez, M., Mancuso, R., Peris-Yague, A., Simmons, C., NIMA Consortium, Wlazly, D., Dickinson, A., Foster, A., Knight, C., Leckey, C., et al. (2023) · Journal of Neuroinflammation

Neuroinflammation and Neurodegeneration MechanismsPrion Diseases and Protein Misfolding

Cited by 17

Effect of trazodone on cognitive decline in people with dementia: Cohort study using UK routinely collected data

Sommerlad, A., Werbeloff, N., Perera, G., Smith, T., Costello, H., Mueller, C., Kormilitzin, A., Broadbent, M., Nevado‐Holgado, A., Lovestone, S., et al. (2022) · International Journal of Geriatric Psychiatry

Dementia and Cognitive Impairment ResearchTreatment of Major Depression

Cited by 14

Characterization of APOE Christchurch carriers in 455,306 UK Biobank participants

He, K. Y., Khramtsova, E. A., Cabrera-Socorro, A., Zhang, Y., Li, S., Sarver, B. A. J., Smets, B., Li, Q. S., De Muynck, L., Parrado, A. R., et al. (2023) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 8

Apolipoprotein E (apoE) uptake and distribution in mammalian cell lines is dependent upon source of apoE and can be monitored in living cells

Ljungberg, M. C., Asuni, A., Pearce, J., Dayanandan, R., März, W., Hoffmann, M. M., Bertrand, P., Siest, G., Rupniak, H. T. R., Anderton, B. H., et al. (2003) · Neuroscience Letters

Alzheimer's disease research and treatmentsCholesterol and Lipid Metabolism

Cited by 2

Multiomics machine learning identifies inflammation molecular pathways in prodromal Alzheimer’s Disease

Gómez-Pascual, A., Naccache, T., Xu, J., Hooshmand, K., Wretlind, A., Gabrielli, M., Lombardo, M. T., Shi, L., Buckley, N. J., Tijms, B. M., et al. (2023) · medRxiv

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 1