Stimulation of MAP kinase by v‐raf transformation of fibroblasts fails to induce hyperphosphorylation of transfected tau

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

Goedert, M., Spillantini, M. G., Jakes, R., Rutherford, D., & Crowther, R. A. (1989) · Neuron · doi:10.1016/0896-6273(89)90210-9 · Cited by 2,492 · see citing works

Raf-1 activates MAP kinase-kinase

Kyriakis, J. M., App, H., Zhang, X., Banerjee, P. T., Brautigan, D. L., Rapp, U. R., & Avruch, J. (1992) · Nature · doi:10.1038/358417a0 · Cited by 1,263 · see citing works

Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding

Bramblett, G. T., Goedert, M., Jakes, R., Merrick, S. E., Trojanowski, J. Q., & Lee, V. M. Y. (1993) · Neuron · doi:10.1016/0896-6273(93)90057-x · Cited by 903 · see citing works

Activation of the MAP kinase pathway by the protein kinase raf

Howe, L. R., Leevers, S. J., Gómez, N., Nakielny, S., Cohen, P., & Marshall, C. J. (1992) · Cell · doi:10.1016/0092-8674(92)90361-f · Cited by 801 · see citing works

Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: Distinction between PHF-like immunoreactivity and microtubule binding

Biernat, J., Gustke, N., Drewes, G., Mandelkow, E., & Mandelkow, E. (1993) · Neuron · doi:10.1016/0896-6273(93)90279-z · Cited by 796 · see citing works

Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: Generation of paired helical filament epitopes and neuronal localisation of the kinase

Hanger, D. P., Hughes, K., Woodgett, J. R., Brion, J.-P., & Anderton, B. H. (1992) · Neuroscience Letters · doi:10.1016/0304-3940(92)90774-2 · Cited by 737 · see citing works

Tau protein and the neurofibrillary pathology of Alzheimer's disease

Goedert, M. (1993) · Trends in Neurosciences · doi:10.1016/0166-2236(93)90078-z · Cited by 718 · see citing works

Activation of Mitogen-Activated Protein Kinase Kinase by v-Raf in NIH 3T3 Cells and in Vitro

Dent, P., Haser, W. G., Haystead, T., Vincent, L. A., Roberts, T. M., & Sturgill, T. W. (1992) · Science · doi:10.1126/science.1326789 · Cited by 668 · see citing works

Inhibition of neurite polarity by tau antisense oligonucleotides in primary cerebellar neurons

Cáceres, A., & Kosik, K. S. (1990) · Nature · doi:10.1038/343461a0 · Cited by 656 · see citing works

Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau.

Matsuo, E. S., Shin, R., Billingsley, M., de Voorde, A. V., O'Connor, M., Trojanowski, J., & Lee, V. (1994) · Neuron · doi:10.1016/0896-6273(94)90264-x · Cited by 588 · see citing works

Mitogen activated protein (MAP) kinase transforms tau protein into an Alzheimer‐like state.

Drewes, G., Lichtenberg‐Kraag, B., Döring, F., Mandelkow, E. M., Biernat, J., Goris, J., Dorée, M., & Mandelkow, E. (1992) · The EMBO Journal · doi:10.1002/j.1460-2075.1992.tb05272.x · Cited by 565 · see citing works

Glycogen synthase kinase‐3 and the Alzheimer‐like state of microtubule‐associated protein tau

Mandelkow, E.-M., Drewes, G., Biernat, J., Gustke, N., Van Lint, J., Vandenheede, J. R., & Mandelkow, E. (1992) · FEBS Letters · doi:10.1016/0014-5793(92)81496-9 · Cited by 515 · see citing works

The switch of tau protein to an Alzheimer‐like state includes the phosphorylation of two serine‐proline motifs upstream of the microtubule binding region.

Biernat, J., Mandelkow, E. M., Schröter, C., Lichtenberg‐Kraag, B., Steiner, B., Berling, B., Meyer, H., Mercken, M., Vandermeeren, A., & Goedert, M. (1992) · The EMBO Journal · doi:10.1002/j.1460-2075.1992.tb05204.x · Cited by 484 · see citing works

The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated protein kinase pathway in L6 cells between Ras and Raf

Cross, D. A. E., Alessi, D. R., Vandenheede, J. R., McDowell, H. E., Hundal, H. S., & Cohen, P. (1994) · Biochemical Journal · doi:10.1042/bj3030021 · Cited by 474 · see citing works

Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells

Lovestone, S., Reynolds, C. H., Latimer, D. A., Davis, D. R., Anderton, B. H., Gallo, J., Hanger, D. P., Mulot, S., Marquardt, B., Stabel, S., et al. (1994) · Current Biology · doi:10.1016/s0960-9822(00)00246-3 · Cited by 470 · see citing works

Protein sequence and mass spectrometric analyses of tau in the Alzheimer's disease brain

Hasegawa, M., Morishima-Kawashima, M., Takio, K., Suzuki, M., Titani, K., & Ihara, Y. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)41890-x · Cited by 430 · see citing works

Glycogen synthase kinase 3β is identical to tau protein kinase I generating several epitopes of paired helical filaments

Ishiguro, K., Shiratsuchi, A., Sato, S., Omori, A., Arioka, M., Kobayashi, S., Uchida, T., & Imahori, K. (1993) · FEBS Letters · doi:10.1016/0014-5793(93)81066-9 · Cited by 402 · see citing works

Expression of multiple tau isoforms and microtubule bundle formation in fibroblasts transfected with a single tau cDNA.

Kanai, Y., Takemura, R., Oshima, T., Mori, H., Ihara, Y., Yanagisawa, M., Masaki, T., & Hirokawa, N. (1989) · The Journal of Cell Biology · doi:10.1083/jcb.109.3.1173 · Cited by 360 · see citing works

Phosphorylation of tau proteins to a state like that in Alzheimer's brain is catalyzed by a calcium/calmodulin-dependent kinase and modulated by phospholipids.

Baudier, J., & Cole, R. D. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)45420-8 · Cited by 263 · see citing works

Neurotrophic factor therapy for nervous system degenerative diseases

Hefti, F. F. (1994) · Journal of Neurobiology · doi:10.1002/neu.480251109 · Cited by 251 · see citing works

In vivo phosphorylation sites in fetal and adult rat tau

Watanabe, A., Hasegawa, M., Suzuki, M., Takio, K., Morishima-Kawashima, M., Titani, K., Arai, T., Kosik, K. S., & Ihara, Y. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)74447-0 · Cited by 231 · see citing works

The Alzheimer‐like phosphorylation of tau protein reduces microtubule binding and involves Ser‐Pro and Thr‐Pro motifs

Gustke, N., Steiner, B., Mandelkow, E., Biernat, J., Meyer, H. E., Goedert, M., & Mandelkow, E. (1992) · FEBS Letters · doi:10.1016/0014-5793(92)80767-b · Cited by 219 · see citing works

Inactivation of Glycogen Synthase Kinase-3 by Epidermal Growth Factor Is Mediated by Mitogen-activated Protein Kinase/p90 Ribosomal Protein S6 Kinase Signaling Pathway in NIH/3T3 Cells

Eldar-Finkelman, H., Seger, R., Vandenheede, J. R., & Krebs, E. G. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.3.987 · Cited by 214 · see citing works

NuMA is required for the proper completion of mitosis.

Compton, D. A., & Cleveland, D. W. (1993) · The Journal of Cell Biology · doi:10.1083/jcb.120.4.947 · Cited by 214 · see citing works

Developmental Changes in τ Phosphorylation: Fetal τ Is Transiently Phosphorylated in a Manner Similar to Paired Helical Filament‐τ Characteristic of Alzheimer's Disease

Brion, J., Smith, C. J., Couck, A., Gallo, J., & Anderton, B. H. (1993) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1993.tb07444.x · Cited by 202 · see citing works

Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase

Welsh, G. I., Foulstone, E. J., Young, S. W., Tavaré, J. M., & Proud, C. G. (1994) · Biochemical Journal · doi:10.1042/bj3030015 · Cited by 200 · see citing works

Phosphorylation of recombinant tau by cAMP-dependent protein kinase. Identification of phosphorylation sites and effect on microtubule assembly.

Scott, C. W., Spreen, R. C., Herman, J. L., Chow, F. P., Davison, M. D., Young, J., & Caputo, C. B. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)54055-2 · Cited by 200 · see citing works

The effect of tau antisense oligonucleotides on neurite formation of cultured cerebellar macroneurons

Cáceres, A., Potrebic, S., & Kosik, K. S. (1991) · Journal of Neuroscience · doi:10.1523/jneurosci.11-06-01515.1991 · Cited by 193 · see citing works

The extent of phosphorylation of fetal tau is comparable to that of PHF-tau from Alzheimer paired helical filaments

Kenessey, Á., & Yen, S.-H. C. (1993) · Brain Research · doi:10.1016/0006-8993(93)90478-6 · Cited by 167 · see citing works

Identification of the 23 kDa subunit of tau protein kinase II as a putative activator of cdk5 in bovine brain

Ishiguro, K., Kobayashi, S., Onion, A., Takamatsu, M., Yonekura, S., Anzai, K., Imahori, K., & Uchida, T. (1994) · FEBS Letters · doi:10.1016/0014-5793(94)80501-6 · Cited by 147 · see citing works

The mechanism by which epidermal growth factor inhibits glycogen synthase kinase 3 in A431 cells

Saito, Y., Vandenheede, J. R., & Cohen, P. (1994) · Biochemical Journal · doi:10.1042/bj3030027 · Cited by 146 · see citing works

Distribution of the phosphorylated microtubule-associated protein tau in developing cortical neurons

Brion, J., Octave, J., & Couck, A. M. (1994) · Neuroscience · doi:10.1016/0306-4522(94)90533-9 · Cited by 141 · see citing works

Intracranial infusion of purified nerve growth factor to an Alzheimer patient: The first attempt of a possible future treatment strategy

Seiger, Å., Nordberg, A. K., von Holst, H., Bäckman, L., Ebendal, T., Alafuzoff, I. I., Amberla, K., Hartvig, P., Herlitz, A., Lilja, A., et al. (1993) · Behavioural Brain Research · doi:10.1016/0166-4328(93)90141-c · Cited by 137 · see citing works

Functional studies of Alzheimer's disease tau protein

Lu, Q., & Jg, W. (1993) · Journal of Neuroscience · doi:10.1523/jneurosci.13-02-00508.1993 · Cited by 96 · see citing works

PHF‐tau from Alzheimer's brain comprises four species on SDS‐PAGE which can be mimicked by in vitro phosphorylation of human brain tau by glycogen synthase kinase‐3β

Mulot, S., Hughes, K., Woodgett, J. R., Anderton, B. H., & Hanger, D. P. (1994) · FEBS Letters · doi:10.1016/0014-5793(94)00702-0 · Cited by 96 · see citing works

τ Phosphorylation in Human, Primate, and Rat Brain: Evidence that a Pool of τ Is Highly Phosphorylated In Vivo and Is Rapidly Dephosphorylated In Vitro

Garver, T. D., Harris, K. A., Lehman, R. A. W., Lee, V., Trojanowski, J., & Billingsley, M. (1994) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1994.63062279.x · Cited by 80 · see citing works

Neurofilament Monoclonal Antibodies RT97 and 8D8 Recognize Different Modified Epitopes in Paired Helical Filament‐τ in Alzheimer's Disease

Brion, J., Couck, A., Robertson, J., Loviny, T. L. F., & Anderton, B. H. (1993) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1993.tb03298.x · Cited by 61 · see citing works

Differential Phosphorylation of τ by Cyclic AMP‐Dependent Protein Kinase and Ca2+/Calmodulin‐Dependent Protein Kinase II: Metabolic and Functional Consequences

Johnson, G. V. W. (1992) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1992.tb10094.x · Cited by 55 · see citing works

Phosphorylation of tau by proline-directed protein kinase (p34cdc2/p58cyclin A) decreases tau-induced microtubule assembly and antibody SMI33 reactivity

Scott, C. W., Vulliet, P. R., & Caputo, C. B. (1993) · Brain Research · doi:10.1016/0006-8993(93)90508-k · Cited by 40 · see citing works

Phosphate‐Dependent Monoclonal Antibodies to Neurofilaments and Alzheimer Neurofibrillary Tangles Recognize a Synthetic Phosphopeptide

Coleman, M. P., & Anderton, B. H. (1990) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1990.tb01203.x · Cited by 40 · see citing works

Expression and phosphorylation of a three-repeat isoform of tau in transfected non-neuronal cells

Gallo, J., Hanger, D. P., Twist, E. C., Kosik, K. S., & Anderton, B. H. (1992) · Biochemical Journal · doi:10.1042/bj2860399 · Cited by 35 · see citing works

Phosphorylation of Tau by Cyclic-AMP-Dependent Protein Kinase

Robertson, J., Loviny, T. L. F., Goedert, M., Jakes, R., Murray, K. J., Anderton, B. H., & Hanger, D. P. (1993) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000107331 · Cited by 32 · see citing works

Human tau isoforms confer distinct morphological and functional properties to stably transfected fibroblasts.

Lo, M., Fieles, A., Norris, T., Dargis, P., Caputo, C., Scott, C. W., Lee, V. M.-Y., & Goedert, M. (1993) · Brain Research. Molecular Brain Research · doi:10.1016/0169-328x(93)90043-o · Cited by 27 · see citing works

Tau protein and Alzheimer's disease

Mandelkow, E., & Mandelkow�, E. (1994) · Neurobiology of Aging · doi:10.1016/0197-4580(94)90178-3 · Cited by 25 · see citing works

Signal Transduction through MAP Kinase Cascades

Lewis, T. S., Shapiro, P. S., & Ahn, N. G. (1998) · Advances in cancer research · doi:10.1016/s0065-230x(08)60765-4 · Cited by 1,746 · see citing works

Insulin and Insulin-like Growth Factor-1 Regulate Tau Phosphorylation in Cultured Human Neurons*

Hong, M., & Lee, V. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.31.19547 · Cited by 533 · see citing works

Microtubule-associated protein tau in development, degeneration and protection of neurons

Wang, J., & Liu, F. (2008) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2008.03.002 · Cited by 395 · see citing works

The Role of Mitogen-Activated Protein Kinase Pathways in Alzheimer’s Disease

Zhu, X., Lee, H., Raina, A. K., Perry, G. L., & Smith, M. A. (2002) · Neurosignals · doi:10.1159/000067426 · Cited by 392 · see citing works

α-synuclein in the pathophysiology of Alzheimer’s disease

Twohig, D., & Nielsen, H. M. (2019) · Molecular Neurodegeneration · doi:10.1186/s13024-019-0320-x · Cited by 374 · see citing works

Therapeutic approaches to Alzheimer's disease

Klafki, H., Staufenbiel, M., Kornhuber, J., & Wiltfang, J. (2006) · Brain · doi:10.1093/brain/awl280 · Cited by 359 · see citing works

Regulation of mitochondrial pyruvate dehydrogenase activity by tau protein kinase I/glycogen synthase kinase 3beta in brain.

Hoshi, M. M., Takashima, A., Noguchi, K., Murayama, M., Sato, M., Kondo, S., Saitoh, Y., Ishiguro, K., Hoshino, T., & Imahori, K. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.7.2719 · Cited by 277 · see citing works

Exposure of rat hippocampal neurons to amyloid β peptide (25–35) induces the inactivation of phosphatidyl inositol-3 kinase and the activation of tau protein kinase I/glycogen synthase kinase-3β

Takashima, A., Noguchi, K., Michel, G., Mercken, M., Hoshi, M., Ishiguro, K., & Imahori, K. (1996) · Neuroscience Letters · doi:10.1016/0304-3940(95)12257-5 · Cited by 260 · see citing works

Preferential labeling of Alzheimer neurofibrillary tangles with antisera for tau protein kinase (TPK) I/glycogen synthase kinase-3β and cyclin-dependent kinase 5, a component of TPK II

Yamaguchi, H., Ishiguro, K., Uchida, T., Takashima, A., Lemere, C. A., & Imahori, K. (1996) · Acta Neuropathologica · doi:10.1007/s004010050513 · Cited by 253 · see citing works

Up-regulation of mitogen-activated protein kinases ERK1/2 and MEK1/2 is associated with the progression of neurofibrillary degeneration in Alzheimer’s disease

Pei, J.-J., Braak, H., An, W.-L., Winblad, B., Cowburn, R. F., Iqbal, K., & Grundke-Iqbal, I. (2002) · Molecular Brain Research · doi:10.1016/s0169-328x(02)00488-6 · Cited by 247 · see citing works

Overactivation of glycogen synthase kinase‐3 by inhibition of phosphoinositol‐3 kinase and protein kinase C leads to hyperphosphorylation of tau and impairment of spatial memory

Liu, S. J., Zhang, A. H., Li, H. L., Wang, Q., Deng, H. M., Netzer, W. J., Xu, H., & Wang, J. Z. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.02070.x · Cited by 224 · see citing works

Phosphorylation of tau by glycogen synthase kinase-3β in intact mammalian cells: The effects on the organization and stability of microtubules

Lovestone, S., Hartley, C. L., Pearce, J., & Anderton, B. H. (1996) · Neuroscience · doi:10.1016/0306-4522(96)00126-1 · Cited by 201 · see citing works

Activation of the L Voltage-sensitive Calcium Channel by Mitogen-activated Protein (MAP) Kinase following Exposure of Neuronal Cells to β-Amyloid

Ekinci, F. J., Malik, K. U., & Shea, T. B. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.42.30322 · Cited by 161 · see citing works

Potentiation of GSK-3-catalyzed Alzheimer-like phosphorylation of human tau by cdk5

Sengupta, A., Wu, Q., Grundke, I., Iqbal, K., & Singh, T. J. (1997) · Molecular and Cellular Biochemistry · doi:10.1023/a:1006883924775 · Cited by 160 · see citing works

Roles of Glycogen Synthase Kinase 3 in Alzheimer’s Disease

Cai, Z., Zhao, Y. C., & Zhao, B. (2012) · Current Alzheimer Research · doi:10.2174/156720512802455386 · Cited by 146 · see citing works

Okadaic-Acid-Induced Inhibition of Protein Phosphatase 2A Produces Activation of Mitogen-Activated Protein Kinases ERK1/2, MEK1/2, and p70 S6, Similar to That in Alzheimer's Disease

Pei, J.-J., Gong, C., An, W., Winblad, B. G., Cowburn, R. F., Grundke, I., & Iqbal, K. (2003) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)63445-1 · Cited by 142 · see citing works

Expression analysis of glycogen synthase kinase‐3 in human tissues

Lau, K., Miller, C. C. J., Anderton, B. H., & Shaw, P. C. (1999) · Journal of Peptide Research · doi:10.1034/j.1399-3011.1999.00083.x · Cited by 113 · see citing works

Dendritic changes in Alzheimer's disease and factors that may underlie these changes

Anderton, B. H., Callahan, L. M., Coleman, P. D., Davies, P., Flood, D. G., Jicha, G. A., Ohm, T. G., & Weaver, C. L. (1998) · Progress in Neurobiology · doi:10.1016/s0301-0082(98)00022-7 · Cited by 111 · see citing works

Expression and regulation of the LIM-class homeobox generlim-1 in neuronal progenitors of the rat cerebellum

Hayes, W. P., Yangco, N., Chin, H. R., Mill, J. F., Pu, L. P., Taira, M., Dawid, I. B., & Gallo, V. (2001) · Journal of Neuroscience Research · doi:10.1002/1097-4547(20010201)63:3 · Cited by 7 · see citing works

Phosphorylation of tau by glycogen synthase kinase 3β affects the ability of tau to promote microtubule self-assembly

Utton, M. A., Vandecandelaere, A., Wagner, U., Reynolds, C. H., Gibb, G., Miller, C. C. J., Bayley, P. M., & Anderton, B. H. (1997) · Biochemical Journal · doi:10.1042/bj3230741 · Cited by 86 · see citing works

Role of GSK‐3β in Alzheimer's disease pathology

Planel, E., Sun, X., & Takashima, A. (2002) · Drug Development Research · doi:10.1002/ddr.10100 · Cited by 85 · see citing works

Changes in the ageing brain in health and disease

Anderton, B. H. (1997) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.1997.0162 · Cited by 78 · see citing works

Phosphorylation of microtubule‐associated protein tau by stress‐activated protein kinases in intact cells

Buée‐Scherrer, V., & Goedert, M. (2002) · FEBS Letters · doi:10.1016/s0014-5793(02)02460-2 · Cited by 76 · see citing works

Isolation and chromosomal mapping of human glycogen synthase kinase-3 α and -3β encoding genes

Shaw, P., Davies, A. F., Lau, K., Garcia-Barceló, M., Waye, M. M. Y., Lovestone, S., Miller, C. C. J., & Anderton, B. H. (1998) · Genome · doi:10.1139/gen-41-5-720 · Cited by 67 · see citing works

The Environmental Toxin Arsenite Induces Tau Hyperphosphorylation

Giasson, B. I., Sampathu, D. M., Wilson, C., Vogelsberg-Ragaglia, V., Mushynski, W. E., & Lee, V. M. ‐. (2002) · Biochemistry · doi:10.1021/bi026813c · Cited by 66 · see citing works

Mitotic phosphorylation of tau protein in neuronal cell lines resembles phosphorylation in Alzheimer's disease

Preuß, U., & Mandelkow, E. (1998) · European Journal of Cell Biology · doi:10.1016/s0171-9335(98)80032-0 · Cited by 66 · see citing works

LiCl Attenuates Thapsigargin-Induced Tau Hyperphosphorylation by Inhibiting GSK-3β In Vivo and In Vitro

Fu, Z., Yang, Y., Song, J., Jiang, Q., Liu, Z.-C., Wang, Q., Zhu, L., Wang, J., & Tian, Q. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-100687 · Cited by 64 · see citing works

Site-specific regulation of Alzheimer-like tau phosphorylation in living neurons

Burack, M. A., & Halpain, S. (1996) · Neuroscience · doi:10.1016/0306-4522(95)00546-3 · Cited by 35 · see citing works

Activation of mitogen-activated protein kinase cascade and phosphorylation of cytoskeletal proteins after neurone-specific activation of p21ras. II. Cytoskeletal proteins and dendritic morphology

Holzer, M., Rödel, L., Seeger, G., Gärtner, U., Narz, F., Janke, C., Heumann, R., & Arendt, T. (2001) · Neuroscience · doi:10.1016/s0306-4522(01)00246-9 · Cited by 34 · see citing works

Acute anoxia induces tau dephosphorylation in rat brain slices and its possible underlying mechanisms

Liu, R., Pei, J.-J., Wang, X., Zhou, X., Tian, Q., Winblad, B. G., & Wang, J. (2005) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2005.03270.x · Cited by 31 · see citing works

Hyperactivation of Mitogen-Activated Protein Kinase Increases Phospho-Tau Immunoreactivity Within Human Neuroblastoma: Additive and Synergistic Influence of Alteration of Additional Kinase Activities

Ekinci, F. J., & SHEA, T. B. (1999) · Cellular and Molecular Neurobiology · doi:10.1023/a:1006981228331 · Cited by 29 · see citing works

Stress-Induced Tau Phosphorylation in Mouse Strains with Different Brain Erk 1 + 2 Immunoreactivity

Korneyev, A. (1998) · Neurochemical Research · doi:10.1023/a:1020980004539 · Cited by 28 · see citing works

τ kinases in the rat heat shock model: Possible implications for Alzheimer disease

Shanavas, A., & Papasozomenos, S. C. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.26.14139 · Cited by 27 · see citing works

Free PKC catalytic subunits (PKM) phosphorylate tau via a pathway distinct from that utilized by intact PKC

Ekinci, F. J., & SHEA, T. B. (1999) · Brain Research · doi:10.1016/s0006-8993(99)02146-0 · Cited by 26 · see citing works

Okadaic acid mediates tau phosphorylation via sustained activation of the L-voltage-sensitive calcium channel

Ekinci, F. J., Ortiz, D., & Shea, T. B. (2003) · Molecular Brain Research · doi:10.1016/s0169-328x(03)00294-8 · Cited by 21 · see citing works

The Order of Exposure of Tau to Signal Transduction Kinases Alters the Generation of “AD-Like” Phosphoepitopes

Shea, T. B., & Cressman, C. M. (1999) · Cellular and Molecular Neurobiology · doi:10.1023/a:1006977127422 · Cited by 19 · see citing works

Inhibition of PHF-like Tau Hyperphosphorylation in SH-SY5Y Cells and Rat Brain Slices by K252a

Hübinger, G., Geis, S., LeCorre, S., Mühlbacher, S., Gordon, S. L., Fracasso, R. P., Hoffman, F., Ferrand, S., Klafki, H., & Roder, H. M. (2008) · Journal of Alzheimer s Disease · doi:10.3233/jad-2008-13306 · Cited by 15 · see citing works

Arsenic and Tau Phosphorylation: A Mechanistic Review

Ariafar, S., Makhdoomi, S., & Mohammadi, M. (2023) · Biological Trace Element Research · doi:10.1007/s12011-023-03634-y · Cited by 13 · see citing works

Overactivated mitogen-activated protein kinase by anisomycin induces tau hyperphosphorylation.

Wang, Q., Zhang, J.-Y., Liu, S. J., & Li, H. L. (2008) · PubMed · Cited by 11 · see citing works

Protein kinases involved in the phosphorylation of human tau protein in transfected COS-1 cells

Medina, M., Garcı́a-Rocha, M., Padilla, R., Pérez, M., de Garcini, E. M., & Ávila, J. (1996) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/0925-4439(96)00018-x · Cited by 9 · see citing works

Molecular cloning and expression analysis of human glycogen synthase kinase-3α promoter

Lee, C., Chan, J. Y.-C., Lau, K., Lee, C. W., Miller, C. C. J., Anderton, B. H., & Shaw, P. (2000) · Molecular Brain Research · doi:10.1016/s0169-328x(00)00238-2 · Cited by 8 · see citing works

Influence of Phospholipids and Sequential Kinase Activities on Tau in Vitro

SHEA, T. B., & Ekinci, F. J. (1998) · Advances in experimental medicine and biology · doi:10.1007/978-1-4615-4869-0_11 · Cited by 3 · see citing works

Oxidative stress and death domain proteins in Alzheimer's disease

Villar, K. D., & Miller, C. A. (2003) · Clinical Neuroscience Research · doi:10.1016/s1566-2772(03)00008-2 · Cited by 2 · see citing works

Tauopathy and Brain Aging

Takashima, A. (2011) · Advances in neurobiology · doi:10.1007/978-1-4419-6787-9_5 · Cited by 1 · see citing works

Depression and anxiety among older Caribbean people in the UK: screening, unmet need and the provision of appropriate services

Abas, M. (1996) · International Journal of Geriatric Psychiatry · doi:10.1002/(sici)1099-1166(199604)11:4 · Cited by 21 · see citing works

Distinct Tau Gene Mutations Induce Specific Dysfunctions/Toxic Properties in Tau Proteins Associated With Specific FTDP-17 Phenotypes

Lee, V. M. Y., & Trojanowski, J. Q. (2000) · Research and perspectives in Alzheimer's disease · doi:10.1007/978-3-662-04056-0_7 · Cited by 1 · see citing works

Overinhibition of mitogen-activated protein kinase inducing tau hyperphosphorylation

Li, H., Chen, J., Shi-jie, L., Zhang, J. Y., Qun, W., & Wang, J. (2005) · Wuhan University Journal of Natural Sciences · doi:10.1007/bf02831155

Scouting Biomarkers for Alzheimer’s Disease via Network Analysis of Exosome Proteomics Data

Sagonas, A., Apostolakou, A. E., Litou, Z. I., Antonelou, M. H., & Iconomidou, V. A. (2025) · BioMedInformatics · doi:10.3390/biomedinformatics5020019

Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells

Lovestone, S., Reynolds, C. H., Latimer, D. A., Davis, D. R., Anderton, B. H., Gallo, J., Hanger, D. P., Mulot, S., Marquardt, B., Stabel, S., et al. (1994) · Current Biology · doi:10.1016/s0960-9822(00)00246-3 · Cited by 470 · see citing works

Modulation of PHF-like tau phosphorylation in cultured neurones and transfected cells

Anderton, B. H., Brion, J., Couck, A. M., Davis, D. R., Gallo, J., Hanger, D. P., Ladhani, K., Latimer, D. A., Lewis, C., Lovestone, S., et al. (1995) · Neurobiology of Aging · doi:10.1016/0197-4580(94)00160-3 · Cited by 40 · see citing works

Glycogen synthase kinase-3β phosphorylates tau protein at multiple sites in intact cells

Sperbera, B. R., Leight, S., Goedert, M., & Lee, V. M.-Y. (1995) · Neuroscience Letters · doi:10.1016/0304-3940(95)11902-9 · Cited by 204 · see citing works

Transfection with GSK- 3β in vivo induces tau hyperphosphorylation at PHF- 1 sites

Li, H., Wang, S., Xiaomei, L., Wang, X., Wang, Q., & Wang, J. (2006) · Zhongguo bingli shengli zazhi

Overactivated mitogen-activated protein kinase by anisomycin induces tau hyperphosphorylation.

Wang, Q., Zhang, J.-Y., Liu, S. J., & Li, H. L. (2008) · PubMed · Cited by 11 · see citing works