Matthews, Russell T.

Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis

Klivenyi, P., Ferrante, R. J., Matthews, R. T., Bogdanov, M. B., Klein, A. M., Andreassen, O. A., Mueller, G., Wermer, M., Kaddurah-Daouk, R., & Beal, M. F. (1999) · Nature Medicine

Amyotrophic Lateral Sclerosis ResearchMitochondrial Function and Pathology

Cited by 682

Coenzyme Q 10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects

Matthews, R. T., Yang, L., Browne, S., Baik, M., & Beal, M. F. (1998) · Proceedings of the National Academy of Sciences

Coenzyme Q10 studies and effectsMitochondrial Function and Pathology

Cited by 557

Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP-induced neurotoxicity in mice

Schulz, J. B., Matthews, R. T., Muqit, M. M. K., Browne, S. E., & Beal, M. F. (1995) · Journal of Neurochemistry

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 417

Aggrecan Glycoforms Contribute to the Molecular Heterogeneity of Perineuronal Nets

Matthews, R. T., Kelly, G. M., Zerillo, C. A., Gray, G., Tiemeyer, M., & Hockfield, S. (2002) · The Journal of Neuroscience

Proteoglycans and glycosaminoglycans researchGlycosylation and Glycoproteins Research

Cited by 341

Sensory Deprivation Alters Aggrecan and Perineuronal Net Expression in the Mouse Barrel Cortex

McRae, P. A., Rocco, M. M., Kelly, G., Brumberg, J. C., & Matthews, R. T. (2007) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 272

Coenzyme Q10 attenuates the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced loss of striatal dopamine and dopaminergic axons in aged mice

Beal, M. F., Matthews, R. T., Tieleman, A., & Shults, C. W. (1998) · Brain Research

Coenzyme Q10 studies and effectsParkinson's Disease Mechanisms and Treatments

Cited by 256

Perineuronal net formation and structure in aggrecan knockout mice

Giamanco, K. A., Morawski, M., & Matthews, R. T. (2010) · Neuroscience

Proteoglycans and glycosaminoglycans researchNeuroscience and Neuropharmacology Research

Cited by 207

Uncoupling Protein-2 Is Critical for Nigral Dopamine Cell Survival in a Mouse Model of Parkinson's Disease

Andrews, Z. B., Horvath, B., Barnstable, C. J., Elseworth, J., Yang, L., Beal, M. F., Roth, R. H., Matthews, R. T., & Horvath, T. L. (2005) · The Journal of Neuroscience

Parkinson's Disease Mechanisms and TreatmentsMitochondrial Function and Pathology

Cited by 199

Increased chondroitin sulfate proteoglycan expression in denervated brainstem targets following spinal cord injury creates a barrier to axonal regeneration overcome by chondroitinase ABC and neurotrophin-3.

Massey, J. M., Amps, J., Viapiano, M. S., Matthews, R. T., Wagoner, M. R., Whitaker, C. M., Alilain, W., Yonkof, A. L., Khalyfa, A., Cooper, N. G. F., et al. (2008) · Experimental Neurology

Nerve injury and regenerationSpinal Cord Injury Research

Cited by 185

Aggrecan: Beyond cartilage and into the brain

Morawski, M., Brückner, G., Arendt, T., & Matthews, R. T. (2012) · The International Journal of Biochemistry & Cell Biology

Proteoglycans and glycosaminoglycans researchOsteoarthritis Treatment and Mechanisms

Cited by 136

Association between protease-specific proteolytic cleavage of brevican and synaptic loss in the dentate gyrus of kainate-treated rats

Yuan, W., Matthews, R. T., Sandy, J. D., & Gottschall, P. E. (2002) · Neuroscience

Proteoglycans and glycosaminoglycans researchProtease and Inhibitor Mechanisms

Cited by 109

Coenzyme Q10 and nicotinamide and a free radical spin trap protect against MPTP neurotoxicity

Schulz, J. B., Ross Henshaw, D., Matthews, R. T., & Flint Beal, M. (1995) · Experimental Neurology

Parkinson's Disease Mechanisms and TreatmentsCoenzyme Q10 studies and effects

Cited by 103

The extracellular matrix molecule brevican is an integral component of the machinery mediating fast synaptic transmission at the calyx of Held

Blosa, M., Sonntag, M., Jäger, C., Weigel, S., Seeger, J., Frischknecht, R., Seidenbecher, C. I., Matthews, R. T., Arendt, T., Rübsamen, R., et al. (2015) · The Journal of Physiology

Neuroscience and Neuropharmacology ResearchProteoglycans and glycosaminoglycans research

Cited by 74

Antibody recognizing 4-sulfated chondroitin sulfate proteoglycans restores memory in tauopathy-induced neurodegeneration

Yang, S., Hilton, S., Alves, J. N., Saksida, L. M., Bussey, T., Matthews, R. T., Kitagawa, H., Spillantini, M. G., Kwok, J. C. F., & Fawcett, J. W. (2017) · Neurobiology of Aging

Proteoglycans and glycosaminoglycans researchAlzheimer's disease research and treatments

Cited by 61

Candidate Gene Analysis of the Human Natural Killer-1 Carbohydrate Pathway and Perineuronal Nets in Schizophrenia: B3GAT2 Is Associated with Disease Risk and Cortical Surface Area

Kähler, A. K., Djurovic, S., Rimol, L. M., Brown, A. A., Athanasiu, L., Jönsson, E. G., Hansen, T., Gústafsson, Ó., Hall, H., Giegling, I., et al. (2011) · Biological Psychiatry

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 48

The protein tyrosine phosphatase RPTPζ/phosphacan is critical for perineuronal net structure

Eill, G. J., Sinha, A., Morawski, M., Viapiano, M. S., & Matthews, R. T. (2020) · Journal of Biological Chemistry

Neuroscience and Neuropharmacology ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 32

Aggrecan immobilizes to perineuronal nets through hyaluronan-dependent and hyaluronan-independent binding activities

Otsuka, M. Y., Essel, L. B., Sinha, A., Nickerson, G., Mejia, S. M., Edge, A., Matthews, R. T., & Bouyain, S. (2025) · Journal of Biological Chemistry

Proteoglycans and glycosaminoglycans researchOsteoarthritis Treatment and Mechanisms

Cited by 7

The hyaluronan-binding activity of aggrecan is important, but not essential, for its specific insertion into perineuronal nets

Otsuka, M. Y., Essel, L. B., Sinha, A., Nickerson, G., Mejia, S. M., Matthews, R. T., & Bouyain, S. (2024) · Journal of Biological Chemistry

Proteoglycans and glycosaminoglycans researchOsteoarthritis Treatment and Mechanisms

Cited by 7