Sheedy, Frederick J.

Macrophages in atherosclerosis: a dynamic balance

Moore, K. J., Sheedy, F. J., & Fisher, E. A. (2013) · Nature reviews. Immunology

Atherosclerosis and Cardiovascular DiseasesCholesterol and Lipid Metabolism

Cited by 2,559

Pyruvate kinase M2 regulates Hif-1α activity and IL-1β induction and is a critical determinant of the Warburg effect in LPS-activated macrophages

Palsson-McDermott, E. M., Curtis, A. M., Goel, G., Lauterbach, M. A. R., Sheedy, F. J., Gleeson, L. E., van den Bosch, M. W. M., Quinn, S. R., Domingo-Fernandez, R., Johnston, D. G. W., et al. (2015) · Cell Metabolism

Immune cells in cancerCancer, Hypoxia, and Metabolism

Cited by 1,397

Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21

Sheedy, F. J., Palsson-McDermott, E., Hennessy, E. J., Martin, C., O'Leary, J. J., Ruan, Q., Johnson, D. S., Chen, Y., & O'Neill, L. A. J. (2010) · Nature Immunology

Immune Response and InflammationMicroRNA in disease regulation

Cited by 1,005

CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation

Sheedy, F. J., Grebe, A., Rayner, K. J., Kalantari, P., Ramkhelawon, B., Carpenter, S. B., Becker, C. E., Ediriweera, H. N., Mullick, A. E., Golenbock, D. T., et al. (2013) · Nature Immunology

Inflammasome and immune disordersAtherosclerosis and Cardiovascular Diseases

Cited by 935

Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides

Rayner, K. J., Esau, C. C., Hussain, F. N., McDaniel, A. L., Marshall, S. M., van Gils, J. M., Ray, T. D., Sheedy, F. J., Goedeke, L., Liu, X., et al. (2011) · Nature

Cholesterol and Lipid MetabolismMicroRNA in disease regulation

Cited by 706

Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis

Rayner, K. J., Sheedy, F. J., Esau, C. C., Hussain, F. N., Temel, R. E., Parathath, S., van Gils, J. M., Rayner, A. J., Chang, A. N., Suarez, Y., et al. (2011) · Journal of Clinical Investigation

Cholesterol and Lipid MetabolismMicroRNA in disease regulation

Cited by 690

Turning 21: Induction of miR-21 as a Key Switch in the Inflammatory Response

Sheedy, F. J. (2015) · Frontiers in Immunology

MicroRNA in disease regulationImmune Response and Inflammation

Cited by 496

MicroRNA-33-dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis

Ouimet, M., Ediriweera, H. N., Gundra, U. M., Sheedy, F. J., Ramkhelawon, B., Hutchison, S. B., Rinehold, K., van Solingen, C., Fullerton, M. D., Cecchini, K., et al. (2015) · Journal of Clinical Investigation

Atherosclerosis and Cardiovascular DiseasesMicroRNA in disease regulation

Cited by 394

Adding fuel to fire: microRNAs as a new class of mediators of inflammation

Sheedy, F. J., & O'Neill, L. A. J. (2008) · Annals of the Rheumatic Diseases

MicroRNA in disease regulationImmune Response and Inflammation

Cited by 246

Recognition of yeast β-glucan particles triggers immunometabolic signaling required for trained immunity

Horneck Johnston, C. J. H., Ledwith, A. E., Lundahl, M. L. E., Charles-Messance, H., Hackett, E. E., O’Shaughnessy, S. D., Clegg, J., Prendeville, H., McGrath, J. P., Walsh, A. M., et al. (2024) · iScience

Immune responses and vaccinationsImmune Response and Inflammation

Cited by 67

Trained Immunity Causes Myeloid Cell Hypercoagulability

Rehill, A. M., McCluskey, S., Ledwith, A. E., Ryan, T. A. J., Ünlü, B., Leon, G., Charles-Messance, H., Gilbert, E. H., Klavina, P., Day, E. A., et al. (2025) · Science Advances

Immune responses and vaccinationsBlood Coagulation and Thrombosis Mechanisms

Cited by 12