Nutt, Stephen L.

The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells

Cretney, E., Xin, A., Shi, W., Minnich, M., Masson, F., Miasari, M., Belz, G. T., Smyth, G. K., Busslinger, M., Nutt, S. L., et al. (2011) · Nature Immunology

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 605

The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation

Chang, H.-C., Sehra, S., Goswami, R., Yao, W., Yu, Q., Stritesky, G. L., Jabeen, R., McKinley, C., Ahyi, A.-N., Han, L., et al. (2010) · Nature Immunology

T-cell and B-cell ImmunologyAsthma and respiratory diseases

Cited by 577

Dynamic regulation of PU.1 expression in multipotent hematopoietic progenitors

Nutt, S. L., Metcalf, D., D'Amico, A., Polli, M., & Wu, L. (2005) · The Journal of Experimental Medicine

Hematopoietic Stem Cell TransplantationAcute Myeloid Leukemia Research

Cited by 325

PU.1 regulates the commitment of adult hematopoietic progenitors and restricts granulopoiesis

Dakic, A., Metcalf, D., Di Rago, L., Mifsud, S., Wu, L., & Nutt, S. L. (2005) · The Journal of Experimental Medicine

Hematopoietic Stem Cell TransplantationAcute Myeloid Leukemia Research

Cited by 297

The Transcription Factor PU.1 Controls Dendritic Cell Development and Flt3 Cytokine Receptor Expression in a Dose-Dependent Manner

Carotta, S., Dakic, A., D'Amico, A., Pang, S. H. M., Greig, K. T., Nutt, S. L., & Wu, L. (2010) · Immunity

Immunotherapy and Immune ResponsesT-cell and B-cell Immunology

Cited by 279

Positive Feedback Between PU.1 and the Cell Cycle Controls Myeloid Differentiation

Kueh, H. Y., Champhekar, A., Nutt, S. L., Elowitz, M. B., & Rothenberg, E. V. (2013) · Science

Gene Regulatory Network AnalysisDevelopmental Biology and Gene Regulation

Cited by 273

PU.1 controls fibroblast polarization and tissue fibrosis

Wohlfahrt, T., Rauber, S., Uebe, S., Luber, M., Soare, A., Ekici, A., Weber, S., Matei, A.-E., Chen, C.-W., Maier, C., et al. (2019) · Nature

TGF-β signaling in diseasesLiver physiology and pathology

Cited by 187

PU.1 is a suppressor of myeloid leukemia, inactivated in mice by gene deletion and mutation of its DNA binding domain

Cook, W. D., McCaw, B. J., Herring, C., John, D. L., Foote, S. J., Nutt, S. L., & Adams, J. M. (2004) · Blood

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 140

IFN Regulatory Factor 4 Regulates the Expression of a Subset of Th2 Cytokines

Ahyi, A.-N. N., Chang, H.-C., Dent, A. L., Nutt, S. L., & Kaplan, M. H. (2009) · The Journal of Immunology

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 137

The Interactions of Multiple Cytokines Control NK Cell Maturation

Brady, J., Carotta, S., Thong, R. P. L., Chan, C. J., Hayakawa, Y., Smyth, M. J., & Nutt, S. L. (2010) · The Journal of Immunology

Immune Cell Function and InteractionImmune cells in cancer

Cited by 130

Regulation of Lymphoid versus Myeloid Fate 'choice' by the Transcription Factor Mef2c

Stehling-Sun, S., Dade, J., Nutt, S. L., DeKoter, R. P., & Camargo, F. D. (2009) · Nature Immunology

Hematopoietic Stem Cell TransplantationT-cell and B-cell Immunology

Cited by 125

The role of PLCγ2 in immunological disorders, cancer, and neurodegeneration

Jackson, J. T., Mulazzani, E., Nutt, S. L., & Masters, S. L. (2021) · Journal of Biological Chemistry

Immunodeficiency and Autoimmune DisordersProtein Kinase Regulation and GTPase Signaling

Cited by 113

Transcription Factor PU.1 Promotes Conventional Dendritic Cell Identity and Function via Induction of Transcriptional Regulator DC-SCRIPT

Chopin, M., Lun, A. T., Zhan, Y., Schreuder, J., Coughlan, H., D’Amico, A., Mielke, L. A., Almeida, F. F., Kueh, A. J., Dickins, R. A., et al. (2019) · Immunity

Immunotherapy and Immune ResponsesT-cell and B-cell Immunology

Cited by 104

Inactivation of PU.1 in adult mice leads to the development of myeloid leukemia

Metcalf, D., Dakic, A., Mifsud, S., Di Rago, L., Wu, L., & Nutt, S. (2006) · Proceedings of the National Academy of Sciences

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

Cited by 95

Surprising new roles for PU.1 in the adaptive immune response

Carotta, S., Wu, L., & Nutt, S. L. (2010) · Immunological Reviews

T-cell and B-cell ImmunologyDevelopmental Biology and Gene Regulation

Cited by 93

Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia

McKenzie, M. D., Ghisi, M., Oxley, E. P., Ngo, S., Cimmino, L., Esnault, C., Liu, R., Salmon, J. M., Bell, C. C., Ahmed, N., et al. (2019) · Cell Stem Cell

Acute Myeloid Leukemia ResearchCancer Cells and Metastasis

Cited by 91

Transcription Factors IRF8 and PU.1 Are Required for Follicular B Cell Development and BCL6‐driven Germinal Center Responses

Wang, H., Jain, S., Li, P., Lin, J.-X., Oh, J., Qi, C., Gao, Y., Sun, J., Sakai, T., Naghashfar, Z., et al. (2019) · Proceedings of the National Academy of Sciences

T-cell and B-cell ImmunologyGenomics and Chromatin Dynamics

Cited by 81

Regulation of early T-lineage gene expression and developmental progression by the progenitor cell transcription factor PU.1

Champhekar, A., Damle, S. S., Freedman, G., Carotta, S., Nutt, S. L., & Rothenberg, E. V. (2015) · Genes & Development

T-cell and B-cell ImmunologyDevelopmental Biology and Gene Regulation

Cited by 74

Is PU.1 a dosage-sensitive regulator of haemopoietic lineage commitment and leukaemogenesis?

Dakic, A., Wu, L., & Nutt, S. L. (2007) · Trends in Immunology

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

Cited by 72

PU.1 cooperates with IRF4 and IRF8 to suppress pre-B-cell leukemia

Pang, S. H. M., Minnich, M., Gangatirkar, P., Zheng, Z., Ebert, A., Song, G., Dickins, R. A., Corcoran, L. M., Mullighan, C. G., Busslinger, M., et al. (2016) · Leukemia

Acute Lymphoblastic Leukemia researchGenomics and Chromatin Dynamics

Cited by 69

PU.1 regulates TCR expression by modulating GATA-3 activity

Chang, H.-C., Han, L., Jabeen, R., Carotta, S., Nutt, S. L., & Kaplan, M. H. (2009) · The Journal of Immunology

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 66

PU.1 Is Required for the Developmental Progression of Multipotent Progenitors to Common Lymphoid Progenitors

Pang, S. H. M., de Graaf, C. A., Hilton, D. J., Huntington, N. D., Carotta, S., Wu, L., & Nutt, S. L. (2018) · Frontiers in Immunology

Hematopoietic Stem Cell TransplantationT-cell and B-cell Immunology

Cited by 60

The Transcription Factor PU.1 Regulates γδ T Cell Homeostasis

Jabeen, R., Chang, H.-C., Goswami, R., Nutt, S. L., & Kaplan, M. H. (2011) · PLOS ONE

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 10