Yang, Huanming

Sparse whole-genome sequencing identifies two loci for major depressive disorder

CONVERGE consortium, Cai, N., Bigdeli, T. B., Kretzschmar, W., Li, Y., Liang, J., Song, L., Hu, J., Li, Q., Jin, W., et al. (2015) · Nature

Genetic Associations and EpidemiologyTreatment of Major Depression

Cited by 864

Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

Cortés-Ciriano, I., Lee, J. J.-K., Xi, R., Jain, D., Jung, Y. L., Yang, L., Gordenin, D., Klimczak, L. J., Zhang, C.-Z., Pellman, D. S., et al. (2020) · Nature Genetics

Cancer Genomics and DiagnosticsGenomic variations and chromosomal abnormalities

Cited by 712

Single-Cell Exome Sequencing and Monoclonal Evolution of a JAK2-Negative Myeloproliferative Neoplasm

Hou, Y., Song, L., Zhu, P., Zhang, B., Tao, Y., Xu, X., Li, F., Wu, K., Liang, J., Shao, D., et al. (2012) · Cell

Cancer Genomics and DiagnosticsMyeloproliferative Neoplasms: Diagnosis and Treatment

Cited by 541

Detection of Clinically Relevant Genetic Variants in Autism Spectrum Disorder by Whole-Genome Sequencing

Jiang, Y.-H., Yuen, R. K. C., Jin, X., Wang, M., Chen, N., Wu, X., Ju, J., Mei, J., Shi, Y., He, M., et al. (2013) · The American Journal of Human Genetics

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 474

Dense sampling of bird diversity increases power of comparative genomics

Feng, S., Stiller, J., Deng, Y., Armstrong, J., Fang, Q., Reeve, A. H., Xie, D., Chen, G., Guo, C., Faircloth, B. C., et al. (2020) · Nature

Genomics and Phylogenetic StudiesChromosomal and Genetic Variations

Cited by 459

Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition

Rodriguez-Martin, B., Alvarez, E. G., Baez-Ortega, A., Zamora, J., Supek, F., Demeulemeester, J., Santamarina, M., Ju, Y. S., Temes, J., Garcia-Souto, D., et al. (2020) · Nature Genetics

Genomic variations and chromosomal abnormalitiesCancer Genomics and Diagnostics

Cited by 451

Metagenome-wide association of gut microbiome features for schizophrenia

Zhu, F., Ju, Y., Wang, W., Wang, Q., Guo, R., Ma, Q., Sun, Q., Fan, Y., Xie, Y., Yang, Z., et al. (2020) · Nature Communications

Gut microbiota and healthSchizophrenia research and treatment

Cited by 409

Gut microbiome-related effects of berberine and probiotics on type 2 diabetes (the PREMOTE study)

Zhang, Y., Gu, Y., Ren, H., Wang, S., Zhong, H., Zhao, X., Ma, J., Gu, X., Xue, Y., Huang, S., et al. (2020) · Nature Communications

Berberine and alkaloids researchGut microbiota and health

Cited by 380

Shotgun Metagenomics of 250 Adult Twins Reveals Genetic and Environmental Impacts on the Gut Microbiome

Xie, H., Guo, R., Zhong, H., Feng, Q., Lan, Z., Qin, B., Ward, K. J., Jackson, M. A., Xia, Y., Chen, X., et al. (2016) · Cell Systems

Gut microbiota and healthGenomics and Phylogenetic Studies

Cited by 341

Transplantation of microbiota from drug-free patients with schizophrenia causes schizophrenia-like abnormal behaviors and dysregulated kynurenine metabolism in mice

Zhu, F., Guo, R., Wang, W., Ju, Y., Wang, Q., Ma, Q., Sun, Q., Fan, Y., Xie, Y., Yang, Z., et al. (2020) · Molecular Psychiatry

Tryptophan and brain disordersGut microbiota and health

Cited by 323

Single-cell Stereo-seq reveals induced progenitor cells involved in axolotl brain regeneration

Wei, X., Fu, S., Li, H., Liu, Y., Wang, S., Feng, W., Yang, Y., Liu, X., Zeng, Y.-Y., Cheng, M., et al. (2022) · Science

Neurogenesis and neuroplasticity mechanismsSingle-cell and spatial transcriptomics

Cited by 311

Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer

Akdemir, K. C., Le, V. T., Chandran, S., Li, Y., Verhaak, R. G., Beroukhim, R., Campbell, P. J., Chin, L., Dixon, J. R., Futreal, P. A., et al. (2020) · Nature Genetics

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 283

Sex- and age-related trajectories of the adult human gut microbiota shared across populations of different ethnicities

Zhang, X., Zhong, H., Li, Y., Shi, Z., Ren, H., Zhang, Z., Zhou, X., Tang, S., Han, X., Lin, Y., et al. (2021) · Nature Aging

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 250

10KP: A phylodiverse genome sequencing plan

Cheng, S., Melkonian, M., Smith, S. A., Brockington, S., Archibald, J. M., Delaux, P.-M., Li, F.-W., Melkonian, B., Mavrodiev, E. V., Sun, W., et al. (2018) · GigaScience

Genomics and Phylogenetic StudiesPlant Diversity and Evolution

Cited by 248

Deconvolution of single-cell multi-omics layers reveals regulatory heterogeneity

Liu, L., Liu, C., Quintero, A., Wu, L., Yuan, Y., Wang, M., Cheng, M., Leng, L., Xu, L., Dong, G., et al. (2019) · Nature Communications

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 243

Single-cell spatial transcriptome reveals cell-type organization in the macaque cortex

Chen, A., Sun, Y., Lei, Y., Li, C., Liao, S., Meng, J., Bai, Y., Liu, Z., Liang, Z., Zhu, Z., et al. (2023) · Cell

Single-cell and spatial transcriptomicsNeuroscience and Neuropharmacology Research

Cited by 232

Genome-wide characteristics of de novo mutations in autism

Yuen, R. K., Merico, D., Cao, H., Pellecchia, G., Alipanahi, B., Thiruvahindrapuram, B., Tong, X., Sun, Y., Cao, D., Zhang, T., et al. (2016) · npj Genomic Medicine

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 216

Enhancing CRISPR-Cas9 gRNA efficiency prediction by data integration and deep learning

Xiang, X., Corsi, G. I., Anthon, C., Qu, K., Pan, X., Liang, X., Han, P., Dong, Z., Liu, L., Zhong, J., et al. (2021) · Nature Communications

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 209

Deep functional analysis of synII, a 770-kilobase synthetic yeast chromosome.

Shen, Y., Wang, Y., Chen, T., Gao, F., Gong, J., Abramczyk, D., Walker, R., Zhao, H., Chen, S., Liu, W., et al. (2017) · Science

Fungal and yeast genetics researchMicrobial Metabolic Engineering and Bioproduction

Cited by 202

Novel loci and pathways significantly associated with longevity

Zeng, Y., Nie, C., Min, J., Liu, X., Li, M., Chen, H., Xu, H., Wang, M., Ni, T., Li, Y., et al. (2016) · Scientific Reports

Genetic Associations and EpidemiologyGenetics, Aging, and Longevity in Model Organisms

Cited by 195

PIRD: pan immune repertoire database

Zhang, W., Wang, L., Liu, K., Wei, X., Yang, K., Du, W., Wang, S., Guo, N., Ma, C., Luo, L., et al. (2020) · Bioinformatics

T-cell and B-cell Immunologyvaccines and immunoinformatics approaches

Cited by 166

An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates

Goveia, J., Rohlenova, K., Taverna, F., Treps, L., Conradi, L.-C., Pircher, A., Geldhof, V., de Rooij, L. P. M. H., Kalucka, J., Sokol, L., et al. (2020) · Cancer Cell

Angiogenesis and VEGF in CancerSingle-cell and spatial transcriptomics

Cited by 125

The Asian arowana (Scleropages formosus) genome provides new insights into the evolution of an early lineage of teleosts

Bian, C., Hu, Y., Ravi, V., Kuznetsova, I. S., Shen, X., Mu, X., Sun, Y., You, X., Li, J., Li, X., et al. (2016) · Scientific Reports

Genomics and Phylogenetic StudiesChromosomal and Genetic Variations

Cited by 107

The first chromosome‐level genome for a marine mammal as a resource to study ecology and evolution

Fan, G., Zhang, Y., Liu, X., Wang, J., Sun, Z., Sun, S., Zhang, H., Chen, J., Lv, M., Han, K., et al. (2019) · Molecular Ecology Resources

Genomics and Phylogenetic StudiesChromosomal and Genetic Variations

Cited by 45