Jukema, J. Wouter

Subclinical Thyroid Dysfunction and the Risk of Heart Failure Events: An Individual Participant Data Analysis From 6 Prospective Cohorts

Gencer, B., Collet, T.-H., Virgini, V., Bauer, D. C., Gussekloo, J., Cappola, A. R., Nanchen, D., den Elzen, W. P. J., Balmer, P., Luben, R. N., et al. (2012) · Circulation

Thyroid Disorders and TreatmentsHeart Failure Treatment and Management

Cited by 517

Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism

Stott, D. J., Rodondi, N., Kearney, P. M., Ford, I., Westendorp, R. G. J., Mooijaart, S. P., Sattar, N., Aubert, C. E., Aujesky, D., Bauer, D. C., et al. (2017) · New England Journal of Medicine

Thyroid Disorders and TreatmentsThyroid and Parathyroid Surgery

Cited by 490

Effect of alirocumab, a monoclonal antibody to PCSK9, on long-term cardiovascular outcomes following acute coronary syndromes: Rationale and design of the ODYSSEY Outcomes trial

Schwartz, G. G., Bessac, L., Berdan, L. G., Bhatt, D. L., Bittner, V., Diaz, R., Goodman, S. G., Hanotin, C., Harrington, R. A., Jukema, J. W., et al. (2014) · American Heart Journal

Lipoproteins and Cardiovascular HealthAcute Myocardial Infarction Research

Cited by 408

Metabolomic profiles predict individual multidisease outcomes

Buergel, T., Steinfeldt, J., Ruyoga, G., Pietzner, M., Bizzarri, D., Vojinovic, D., Upmeier zu Belzen, J., Loock, L., Kittner, P., Christmann, L., et al. (2022) · Nature Medicine

Metabolomics and Mass Spectrometry StudiesHealth, Environment, Cognitive Aging

Cited by 406

Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949)

Davies, G., Armstrong, N., Bis, J. C., Bressler, J., Chouraki, V, Giddaluru, S., Hofer, E., Ibrahim-Verbaas, C. A., Kirin, M., Lahti, J., et al. (2015) · Molecular Psychiatry

Genetic Associations and EpidemiologyCognitive Abilities and Testing

Cited by 384

Lipid-reduction variability and antidrug-antibody formation with bococizumab

Ridker, P. M., Tardif, J.-C., Amarenco, P., Duggan, W., Glynn, R. J., Jukema, J. W., Kastelein, J. J. P., Kim, A. M., Koenig, W., Nissen, S., et al. (2017) · New England Journal of Medicine

Lipoproteins and Cardiovascular HealthLipid metabolism and disorders

Cited by 369

A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals

Deelen, J., Kettunen, J., Fischer, K., van der Spek, A., Trompet, S., Kastenmüller, G., Boyd, A., Zierer, J., van den Akker, E. B., Ala-Korpela, M., et al. (2019) · Nature Communications

Metabolomics and Mass Spectrometry StudiesHealth, Environment, Cognitive Aging

Cited by 362

Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis

Dale, C. E., Fatemifar, G., Palmer, T. M., White, J., Prieto-Merino, D., Zabaneh, D., Engmann, J. E. L., Shah, T., Wong, A., Warren, H. R., et al. (2017) · Circulation

Genetic Associations and EpidemiologyCardiovascular Disease and Adiposity

Cited by 345

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

CHARGE-Heart Failure Consortium, Surendran, P., EchoGen Consortium, METASTROKE Consortium, GIANT Consortium, EPIC-InterAct Consortium, Study, L. C., Wellcome Trust Case Control Consortium, Understanding Society Scientific Group, EPIC-CVD Consortium, et al. (2016) · Nature Genetics

Genetic Associations and EpidemiologyBlood Pressure and Hypertension Studies

Cited by 312

Novel genetic loci associated with hippocampal volume

Hibar, D. P., Adams, H. H. H., Jahanshad, N., Chauhan, G., Stein, J. L., Hofer, E., Renteria, M. E., Bis, J. C., Arias-Vasquez, A., Ikram, M. K., et al. (2017) · Nature Communications

Genetic Associations and EpidemiologyMemory and Neural Mechanisms

Cited by 299

Pravastatin and cognitive function in the elderly. Results of the PROSPER study

Trompet, S., Vliet, P., Craen, A. J. M., Jolles, J., Buckley, B. M., Murphy, M. B., Ford, I., Macfarlane, P. W., Sattar, N., Packard, C. J., et al. (2010) · Journal of Neurology

Lipoproteins and Cardiovascular HealthDementia and Cognitive Impairment Research

Cited by 291

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

Teumer, A., Chaker, L., Groeneweg, S., Li, Y., Di Munno, C., Barbieri, C., Schultheiss, U. T., Traglia, M., Ahluwalia, T. S., Akiyama, M., et al. (2018) · Nature Communications

Thyroid Disorders and TreatmentsGenetic Associations and Epidemiology

Cited by 280

Alirocumab in Patients With Polyvascular Disease and Recent Acute Coronary Syndrome

Jukema, J. W., Szarek, M., Zijlstra, L. E., de Silva, H. A., Bhatt, D. L., Bittner, V. A., Diaz, R., Edelberg, J. M., Goodman, S. G., Hanotin, C., et al. (2019) · Journal of the American College of Cardiology

Lipoproteins and Cardiovascular HealthAcute Myocardial Infarction Research

Cited by 243

KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference

Schumann, G., Liu, C., O’Reilly, P., Gao, H., Song, P., Xu, B., Ruggeri, B., Amin, N., Jia, T., Preis, S., et al. (2016) · Proceedings of the National Academy of Sciences

Fibroblast Growth Factor ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 241

Glycated hemoglobin measurement and prediction of cardiovascular disease

Di Angelantonio, E., Gao, P., Khan, H., Butterworth, A. S., Wormser, D., Kaptoge, S., Kondapally Seshasai, S. R., Thompson, A., Sarwar, N., Willeit, P., et al. (2014) · JAMA

Diabetes, Cardiovascular Risks, and LipoproteinsDiabetes Management and Research

Cited by 231

Subclinical Thyroid Dysfunction and the Risk of Heart Failure in Older Persons at High Cardiovascular Risk

Nanchen, D., Gussekloo, J., Westendorp, R. G. J., Stott, D. J., Jukema, J. W., Trompet, S., Ford, I., Welsh, P., Sattar, N., Macfarlane, P. W., et al. (2012) · The Journal of Clinical Endocrinology & Metabolism

Thyroid Disorders and TreatmentsHeart Failure Treatment and Management

Cited by 211

Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation

Sinner, M. F., Tucker, N. R., Lunetta, K. L., Ozaki, K., Smith, J. G., Trompet, S., Bis, J. C., Lin, H., Chung, M. K., Nielsen, J. B., et al. (2014) · Circulation

Cardiac electrophysiology and arrhythmiasAtrial Fibrillation Management and Outcomes

Cited by 205

Alirocumab inhibits atherosclerosis, improves the plaque morphology, and enhances the effects of a statin

Kühnast, S., van der Hoorn, J. W. A., Pieterman, E. J., van den Hoek, A. M., Sasiela, W. J., Gusarova, V., Peyman, A., Schäfer, H.-L., Schwahn, U., Jukema, J. W., et al. (2014) · Journal of Lipid Research

Lipoproteins and Cardiovascular HealthCholesterol and Lipid Metabolism

Cited by 204

Alirocumab Reduces Total Nonfatal Cardiovascular and Fatal Events

Szarek, M., White, H. D., Schwartz, G. G., Alings, M., Bhatt, D. L., Bittner, V. A., Chiang, C.-E., Diaz, R., Edelberg, J. M., Goodman, S. G., et al. (2019) · Journal of the American College of Cardiology

Lipoproteins and Cardiovascular HealthAcute Myocardial Infarction Research

Cited by 173

Body fat distribution, in particular visceral fat, is associated with cardiometabolic risk factors in obese women

Elffers, T. W., de Mutsert, R., Lamb, H. J., de Roos, A., Willems van Dijk, K., Rosendaal, F. R., Jukema, J. W., & Trompet, S. (2017) · PLOS ONE

Cardiovascular Disease and AdiposityDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 167

Effects of statin therapy on diagnoses of new-onset diabetes and worsening glycaemia in large-scale randomised blinded statin trials: an individual participant data meta-analysis

Reith, C., Preiss, D., Blackwell, L., Emberson, J., Spata, E., Davies, K., Halls, H., Harper, C., Holland, L., Wilson, K., et al. (2024) · The Lancet Diabetes & Endocrinology

Lipoproteins and Cardiovascular HealthDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 161

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

Joshi, P. K., Pirastu, N., Kentistou, K. A., Fischer, K., Hofer, E., Schraut, K. E., Clark, D. W., Nutile, T., Barnes, C. L. K., Timmers, P. R. H. J., et al. (2017) · Nature Communications

Genetic Associations and EpidemiologyGenetics, Aging, and Longevity in Model Organisms

Cited by 161

Lipoprotein Lipase S447X: A Naturally Occurring Gain-of-Function Mutation

Rip, J., Nierman, M. C., Ross, C. J., Jukema, J. W., Hayden, M. R., Kastelein, J. J. P., Stroes, E. S. G., & Kuivenhoven, J. A. (2006) · Arteriosclerosis, Thrombosis, and Vascular Biology

Lipid metabolism and disordersLipid metabolism and biosynthesis

Cited by 157

Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese

Lubitz, S. A., Lunetta, K. L., Lin, H., Arking, D. E., Trompet, S., Li, G., Krijthe, B. P., Chasman, D. I., Barnard, J., Kleber, M. E., et al. (2014) · Journal of the American College of Cardiology

Atrial Fibrillation Management and OutcomesGenetic Associations and Epidemiology

Cited by 148