Jukema, J. Wouter

GWAS for executive function and processing speed suggests involvement of the CADM2 gene

Ibrahim-Verbaas, C. A., Bressler, J., Debette, S., Schuur, M., Smith, A. V., Bis, J. C., Davies, G., Trompet, S., Smith, J. A., Wolf, C., et al. (2016) · Molecular Psychiatry

Genetic Associations and EpidemiologyCognitive Abilities and Testing

Cited by 147

Unraveling the directional link between adiposity and inflammation: A bidirectional Mendelian randomization approach

Welsh, P., Polisecki, E., Robertson, M., Jahn, S., Buckley, B. M., de Craen, A. J. M., Ford, I., Jukema, J. W., Macfarlane, P. W., Packard, C. J., et al. (2010) · The Journal of Clinical Endocrinology & Metabolism

Adipokines, Inflammation, and Metabolic DiseasesGenetic Associations and Epidemiology

Cited by 140

An exploratory analysis of proprotein convertase subtilisin/kexin type 9 inhibition and aortic stenosis in the FOURIER trial

Bergmark, B. A., O’Donoghue, M. L., Murphy, S. A., Kuder, J. F., Ezhov, M. V., Ceška, R., Gouni-Berthold, I., Jensen, H. K., Tokgozoglu, S. L., Mach, F., et al. (2020) · JAMA Cardiology

Lipoproteins and Cardiovascular HealthCardiac Valve Diseases and Treatments

Cited by 137

Seven Lipoprotein Lipase Gene Polymorphisms, Lipid Fractions, and Coronary Disease: A HuGE Association Review and Meta-Analysis

Sagoo, G. S., Tatt, I., Salanti, G., Butterworth, A. S., Sarwar, N., van Maarle, M., Jukema, J. W., Wiman, B., Kastelein, J. J. P., Bennet, A. M., et al. (2008) · American Journal of Epidemiology

Lipid metabolism and disordersGenetic Associations and Epidemiology

Cited by 132

Association Between Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical Hypothyroidism

Mooijaart, S. P., Du Puy, R. S., Stott, D. J., Kearney, P. M., Rodondi, N., Westendorp, R. G. J., den Elzen, W. P. J., Postmus, I., Poortvliet, R. K. E., van Heemst, D., et al. (2019) · JAMA

Thyroid Disorders and TreatmentsThyroid and Parathyroid Surgery

Cited by 121

Plasma lipoproteins and apolipoproteins as predictors of cardiovascular risk and treatment benefit in the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER)

Packard, C. J., Ford, I., Robertson, M., Shepherd, J., Blauw, G. J., Murphy, M. B., Bollen, E. L. E. M., Buckley, B. M., Cobbe, S. M., Gaw, A., et al. (2005) · Circulation

Lipoproteins and Cardiovascular HealthCholesterol and Lipid Metabolism

Cited by 121

The dialysis procedure as a trigger for atrial fibrillation: New insights in the development of atrial fibrillation in dialysis patients

Buiten, M. S., de Bie, M. K., Rotmans, J. I., Gabreëls, B. A., van Dorp, W., Wolterbeek, R., Trines, S. A., Schalij, M. J., Jukema, J. W., Rabelink, T. J., et al. (2014) · Heart

Atrial Fibrillation Management and OutcomesDialysis and Renal Disease Management

Cited by 119

Metabolic Age Based on the BBMRI-NL 1 H-NMR Metabolomics Repository as Biomarker of Age-related Disease

van den Akker, E. B., Trompet, S., Barkey Wolf, J. J. H., Beekman, M., Suchiman, H. E. D., Deelen, J., Asselbergs, F. W., Boersma, E., Cats, D., Elders, P. M., et al. (2020) · Circulation: Genomic and Precision Medicine

Metabolomics and Mass Spectrometry StudiesHealth, Environment, Cognitive Aging

Cited by 109

Metabolomic Consequences of Genetic Inhibition of PCSK9 Compared With Statin Treatment

Sliz, E., Kettunen, J., Holmes, M. V., Williams, C. O., Boachie, C., Wang, Q., Männikkö, M., Sebert, S., Walters, R., Lin, K., et al. (2018) · Circulation

Lipoproteins and Cardiovascular HealthCholesterol and Lipid Metabolism

Cited by 109

Association of common genetic variants with brain microbleeds: a genome-wide association study

Knol, M. J., Lu, D., Traylor, M., Adams, H. H. H., Romero, J. R. J., Smith, A. V., Fornage, M., Hofer, E., Liu, J., Hostettler, I. C., et al. (2020) · Neurology

Intracerebral and Subarachnoid Hemorrhage ResearchCerebrovascular and genetic disorders

Cited by 94

Thyroid Function Within the Reference Range and the Risk of Stroke: An Individual Participant Data Analysis

Chaker, L., Baumgartner, C., den Elzen, W. P. J., Collet, T.-H., Ikram, M. A., Blum, M. R., Dehghan, A., Drechsler, C., Luben, R. N., Portegies, M. L. P., et al. (2016) · The Journal of Clinical Endocrinology & Metabolism

Thyroid Disorders and TreatmentsAcute Ischemic Stroke Management

Cited by 92

PCSK9 Loss-of-Function Variants, Low-Density Lipoprotein Cholesterol, and Risk of Coronary Heart Disease and Stroke: Data From 9 Studies of Blacks and Whites

Kent, S. T., Rosenson, R. S., Avery, C. L., Chen, Y.-D. I., Correa, A., Cummings, S. R., Cupples, L. A., Cushman, M., Evans, D. S., Gudnason, V., et al. (2017) · Circulation: Cardiovascular Genetics

Lipoproteins and Cardiovascular HealthGenetic Associations and Epidemiology

Cited by 86

Survival Bias in Mendelian Randomization Studies: A Threat to Causal Inference

Smit, R. A. J., Trompet, S., Dekkers, O. M., Jukema, J. W., & le Cessie, S. (2019) · Epidemiology

Advanced Causal Inference TechniquesGenetic Associations and Epidemiology

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Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications.

Sterenborg, R. B. T. M., Steinbrenner, I., Li, Y., Bujnis, M. N., Naito, T., Marouli, E., Galesloot, T. E., Babajide, O., Andreasen, L., Astrup, A., et al. (2024) · Nature Communications

Genetic Associations and EpidemiologyThyroid Disorders and Treatments

Cited by 79

Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics

The QT Interval International GWAS Consortium (QT-IGC), Lundby, A., Rossin, E. J., Steffensen, A. B., Acha, M. R., Newton-Cheh, C., Pfeufer, A., Lynch, S. N., Olesen, S.-P., Brunak, S., et al. (2014) · Nature Methods

Genetic Associations and EpidemiologyBioinformatics and Genomic Networks

Cited by 71

Subclinical Thyroid Dysfunction and Cognitive Decline in Old Age

Wijsman, L. W., de Craen, A. J. M., Trompet, S., Gussekloo, J., Stott, D. J., Rodondi, N., Welsh, P., Jukema, J. W., Westendorp, R. G. J., & Mooijaart, S. P. (2013) · PLoS ONE

Thyroid Disorders and TreatmentsDementia and Cognitive Impairment Research

Cited by 68

PCSK9 SNP rs11591147 is associated with low cholesterol levels but not with cognitive performance or noncardiovascular clinical events in an elderly population

Postmus, I., Trompet, S., de Craen, A. J. M., Buckley, B. M., Ford, I., Stott, D. J., Sattar, N., Slagboom, P. E., Westendorp, R. G. J., & Jukema, J. W. (2013) · Journal of Lipid Research

Lipoproteins and Cardiovascular HealthCholesterol and Lipid Metabolism

Cited by 67

Type 2 diabetes partitioned polygenic scores associate with disease outcomes in 454,193 individuals across 13 cohorts

DiCorpo, D., LeClair, J., Cole, J. B., Sarnowski, C., Ahmadizar, F., Bielak, L. F., Blokstra, A., Bottinger, E. P., Chaker, L., Chen, Y.-D. I., et al. (2022) · Diabetes Care

Genetic Associations and EpidemiologyDiabetes, Cardiovascular Risks, and Lipoproteins

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Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis

Natarajan, P., Bis, J. C., Bielak, L. F., Cox, A. J., Dörr, M., Feitosa, M. F., Franceschini, N., Guo, X., Hwang, S.-J., Isaacs, A., et al. (2016) · Circulation: Cardiovascular Genetics

Genetic Associations and EpidemiologyAtherosclerosis and Cardiovascular Diseases

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Alirocumab, evinacumab, and atorvastatin triple therapy regresses plaque lesions and improves lesion composition in mice

Pouwer, M. G., Pieterman, E. J., Worms, N., Keijzer, N., Jukema, J. W., Gromada, J., Gusarova, V., & Princen, H. M. G. (2020) · Journal of Lipid Research

Lipoproteins and Cardiovascular HealthAtherosclerosis and Cardiovascular Diseases

Cited by 66

The optimal healthy ranges of thyroid function defined by the risk of cardiovascular disease and mortality: systematic review and individual participant data meta-analysis

Xu, Y., Derakhshan, A., Hysaj, O., Wildisen, L., Ittermann, T., Pingitore, A., Abolhassani, N., Medici, M., Kiemeney, L. A. L. M., Riksen, N. P., et al. (2023) · The Lancet Diabetes & Endocrinology

Thyroid Disorders and TreatmentsThyroid and Parathyroid Surgery

Cited by 61

Addressing residual risk beyond statin therapy: New targets in the management of dyslipidaemias–A report from the European Society of Cardiology Cardiovascular Round Table

Mach, F., Visseren, F. L. J., Cater, N. B., Salhi, N., Soronen, J., Ray, K. K., Delgado, V., Jukema, J. W., Laufs, U., Zamorano, J.-L., et al. (2024) · Journal of Clinical Lipidology

Lipoproteins and Cardiovascular HealthDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 57

Multislice computed tomography coronary angiography for risk stratification in patients with an intermediate pretest likelihood

van Werkhoven, J. M., Gaemperli, O., Schuijf, J. D., Jukema, J. W., Kroft, L. J., Leschka, S., Alkadhi, H., Valenta, I., Pundziute, G., de Roos, A., et al. (2009) · Heart

Cardiac Imaging and DiagnosticsCoronary Interventions and Diagnostics

Cited by 52

Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume

Vojinovic, D., Adams, H. H., Jian, X., Yang, Q., Smith, A. V., Bis, J. C., Teumer, A., Scholz, M., Armstrong, N. J., Hofer, E., et al. (2018) · Nature Communications

Genetic Associations and EpidemiologyCerebrospinal fluid and hydrocephalus

Cited by 52