Savva, George M.

Age, Neuropathology, and Dementia

Savva, G. M., Wharton, S. B., Ince, P. G., Forster, G., Matthews, F. E., & Brayne, C. (2009) · New England Journal of Medicine

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 900

Meta-analysis of the Parkinson’s disease gut microbiome suggests alterations linked to intestinal inflammation

Romano, S., Savva, G. M., Bedarf, J. R., Charles, I. G., Hildebrand, F., & Narbad, A. (2021) · npj Parkinson's Disease

Gut microbiota and healthParkinson's Disease Mechanisms and Treatments

Cited by 707

Anticholinergic Medication Use and Cognitive Impairment in the Older Population: The Medical Research Council Cognitive Function and Ageing Study

Fox, C., Richardson, K., Maidment, I. D., Savva, G. M., Matthews, F. E., Smithard, D., Coulton, S., Katona, C., Boustani, M. A., & Brayne, C. (2011) · Journal of the American Geriatrics Society

Pharmaceutical Practices and Patient OutcomesDementia and Cognitive Impairment Research

Cited by 655

Anticholinergic drugs and risk of dementia: case-control study

Richardson, K., Fox, C., Maidment, I., Steel, N., Loke, Y. K., Arthur, A., Myint, P. K., Grossi, C. M., Mattishent, K., Bennett, K., et al. (2018) · BMJ

Pharmaceutical Practices and Patient OutcomesDementia and Cognitive Impairment Research

Cited by 520

Inflammation and frailty measures in older people

Hubbard, R. E., O’Mahony, M. S., Savva, G. M., Calver, B. L., & Woodhouse, K. W. (2009) · Journal of Cellular and Molecular Medicine

Frailty in Older AdultsNutrition and Health in Aging

Cited by 393

Astrocyte phenotype in relation to Alzheimer‐type pathology in the ageing brain

Simpson, J. E., Ince, P. G., Lace, G., Forster, G., Shaw, P. J., Matthews, F., Savva, G., Brayne, C., & Wharton, S. B. (2010) · Neurobiology of Aging

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 381

Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brain

Parker, A., Romano, S., Ansorge, R., Aboelnour, A., Le Gall, G., Savva, G. M., Pontifex, M. G., Telatin, A., Baker, D., Jones, E., et al. (2022) · Microbiome

Gut microbiota and healthGenetics, Aging, and Longevity in Model Organisms

Cited by 368

Epidemiological Studies of the Effect of Stroke on Incident Dementia: A Systematic Review

Savva, G. M., Stephan, B. C. M., & the Alzheimer’s Society Vascular Dementia Systematic Review Group (2010) · Stroke

Dementia and Cognitive Impairment ResearchAcute Ischemic Stroke Management

Cited by 257

Age-Related Normative Changes in Phasic Orthostatic Blood Pressure in a Large Population Study: Findings From The Irish Longitudinal Study on Ageing (TILDA)

Finucane, C., O’Connell, M. D. L., Fan, C. W., Savva, G. M., Soraghan, C. J., Nolan, H., Cronin, H., & Kenny, R. A. (2014) · Circulation

Cardiovascular Syncope and Autonomic DisordersHeart Rate Variability and Autonomic Control

Cited by 219

Cytomegalovirus infection is associated with increased mortality in the older population

Savva, G. M., Pachnio, A., Kaul, B., Morgan, K., Huppert, F. A., Brayne, C., & Moss, P. A. H. (2013) · Aging Cell

Cytomegalovirus and herpesvirus researchViral-associated cancers and disorders

Cited by 216

Neuropathological correlates of late-life depression in older people

Tsopelas, C., Stewart, R., Savva, G. M., Brayne, C., Ince, P., Thomas, A., & Matthews, F. E. (2011) · British Journal of Psychiatry

Dementia and Cognitive Impairment ResearchTreatment of Major Depression

Cited by 182

Cognitive function in the prefrailty and frailty syndrome

Robertson, D. A., Savva, G. M., Coen, R. F., & Kenny, R. (2014) · Journal of the American Geriatrics Society

Frailty in Older AdultsDementia and Cognitive Impairment Research

Cited by 166

Anticholinergic drugs and incident dementia, mild cognitive impairment and cognitive decline: a meta-analysis

Pieper, N. T., Grossi, C. M., Chan, W.-Y., Loke, Y. K., Savva, G. M., Haroulis, C., Steel, N., Fox, C., Maidment, I. D., Arthur, A. J., et al. (2020) · Age and Ageing

Pharmaceutical Practices and Patient OutcomesDementia and Cognitive Impairment Research

Cited by 138

Low macular pigment optical density is associated with lower cognitive performance in a large, population-based sample of older adults

Feeney, J., Finucane, C., Savva, G. M., Cronin, H., Beatty, S., Nolan, J. M., & Kenny, R. A. (2013) · Neurobiology of Aging

Dementia and Cognitive Impairment ResearchRetinal Diseases and Treatments

Cited by 135

Cognitive function is associated with impaired heart rate variability in ageing adults: the Irish longitudinal study on ageing wave one results.

Frewen, J., Finucane, C., Savva, G. M., Boyle, G., Coen, R. F., & Kenny, R. A. (2013) · Clinical Autonomic Research

Heart Rate Variability and Autonomic ControlDementia and Cognitive Impairment Research

Cited by 119

Alterations of the blood-brain barrier in cerebral white matter lesions in the ageing brain

Simpson, J. E., Wharton, S. B., Cooper, J., Gelsthorpe, C., Baxter, L., Forster, G., Shaw, P. J., Savva, G., Matthews, F. E., Brayne, C., et al. (2010) · Neuroscience Letters

Barrier Structure and Function StudiesCerebrovascular and genetic disorders

Cited by 77

Orthostatic hypotension is associated with lower cognitive performance in adults aged 50 plus with supine hypertension

Frewen, J., Finucane, C., Savva, G. M., Boyle, G., & Kenny, R. A. (2014) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences

Cardiovascular Syncope and Autonomic DisordersDementia and Cognitive Impairment Research

Cited by 76

Adverse effects of Z-drugs for sleep disturbance in people living with dementia: a population-based cohort study

Richardson, K., Loke, Y. K., Fox, C., Maidment, I., Howard, R., Steel, N., Arthur, A., Boyd, P. J., Aldus, C., Ballard, C., et al. (2020) · BMC Medicine

Pharmaceutical Practices and Patient OutcomesSleep and related disorders

Cited by 73

Mesial Temporal Astrocyte Tau Pathology in the MRC-CFAS Ageing Brain Cohort

Lace, G., Ince, P. G., Brayne, C., Savva, G. M., Matthews, F. E., de Silva, R., Simpson, J. E., & Wharton, S. B. (2012) · Dementia and Geriatric Cognitive Disorders

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 52

History of benzodiazepine prescriptions and risk of dementia: possible bias due to prevalent users and covariate measurement timing in a nested case-control study

Richardson, K., Mattishent, K., Loke, Y. K., Steel, N., Fox, C., Grossi, C. M., Bennett, K., Maidment, I., Boustani, M., Matthews, F. E., et al. (2019) · American Journal of Epidemiology

Pharmaceutical Practices and Patient OutcomesDementia and Cognitive Impairment Research

Cited by 36