Maki, Richard A.

A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains

Peyron, C., Faraco, J., Rogers, W., Ripley, B., Overeem, S., Charnay, Y., Nevsimalova, S., Aldrich, M., Reynolds, D., Albin, R., et al. (2000) · Nature Medicine

Sleep and Wakefulness ResearchNeuroscience of respiration and sleep

Cited by 2,118

Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities

McKercher, S. R., Torbett, B. E., Anderson, K. L., Henkel, G. W., Vestal, D. J., Baribault, H., Klemsz, M., Feeney, A. J., Wu, G. E., Paige, C. J., et al. (1996) · The EMBO Journal

Hematopoietic Stem Cell TransplantationT-cell and B-cell Immunology

Cited by 1,130

The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene

Klemsz, M. J., McKercher, S. R., Celada, A., Van Beveren, C., & Maki, R. A. (1990) · Cell

Genomics and Chromatin DynamicsT-cell and B-cell Immunology

Cited by 954

The ETS-domain: a new DNA-binding motif that recognizes a purine-rich core DNA sequence.

Karim, F. D., Urness, L. D., Thummel, C. S., Klemsz, M. J., McKercher, S. R., Celada, A., Van Beveren, C., Maki, R. A., Gunther, C. V., & Nye, J. A. (1990) · Genes & Development

Genomics and Chromatin DynamicsProtein Structure and Dynamics

Cited by 499

PU.1 recruits a second nuclear factor to a site important for immunoglobulin kappa 3' enhancer activity.

Pongubala, J. M., Nagulapalli, S., Klemsz, M. J., McKercher, S. R., Maki, R. A., & Atchison, M. L. (1992) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsT-cell and B-cell Immunology

Cited by 354

Ras-Mediated Phosphorylation of a Conserved Threonine Residue Enhances the Transactivation Activities of c-Ets1 and c-Ets2

Yang, B.-S., Hauser, C. A., Henkel, G., Colman, M. S., Beveren, C. V., Stacey, K. J., Hume, D. A., Maki, R. A., & Ostrowski, M. C. (1996) · Molecular and Cellular Biology

Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases

Cited by 333

A new pattern for helix–turn–helix recognition revealed by the PU.l ETS–domain–DNA complex

Kodandapani, R., Pio, F., Ni, C.-Z., Piccialli, G., Klemsz, M., McKercher, S., Maki, R. A., & Ely, K. R. (1996) · Nature

Protein Structure and DynamicsGenomics and Chromatin Dynamics

Cited by 315

The proto-oncogene PU.1 regulates expression of the myeloid-specific CD11b promoter

Pahl, H. L., Scheibe, R. J., Zhang, D. E., Chen, H. M., Galson, D. L., Maki, R. A., & Tenen, D. G. (1993) · Journal of Biological Chemistry

Genomics and Chromatin DynamicsCell Adhesion Molecules Research

Cited by 301

Effect of PU.1 phosphorylation on interaction with NF-EM5 and transcriptional activation

Pongubala, J., Van Beveren, C., Nagulapalli, S., Klemsz, M., McKercher, Maki, R., & Atchison, M. (1993) · Science

Genomics and Chromatin DynamicsT-cell and B-cell Immunology

Cited by 271

Regulation of lymphoid-specific immunoglobulin mu heavy chain gene enhancer by ETS-domain proteins

Nelsen, B., Tian, G., Erman, B., Gregoire, J., Maki, R., Graves, B., & Sen, R. (1993) · Science

Genomics and Chromatin DynamicsT-cell and B-cell Immunology

Cited by 222

Hematopoietic lineage- and stage-restricted expression of the ETS oncogene family member PU.1

Hromas, R., Orazi, A., Neiman, R., Maki, R., Van Beveran, C., Moore, J., & Klemsz, M. (1993) · Blood

Hematopoietic Stem Cell TransplantationAcute Myeloid Leukemia Research

Cited by 216

Myeloid Development Is Selectively Disrupted in PU.1 Null Mice

Anderson, K. L., Smith, K. A., Conners, K., McKercher, S. R., Maki, R. A., & Torbett, B. E. (1998) · Blood

Hematopoietic Stem Cell TransplantationBlood disorders and treatments

Cited by 193

The transcription factor PU.1 is involved in macrophage proliferation.

Celada, A., Borràs, F. E., Soler, C., Lloberas, J., Klemsz, M., van Beveren, C., McKercher, S., & Maki, R. A. (1996) · The Journal of experimental medicine

Immune cells in cancerGenomics and Chromatin Dynamics

Cited by 152

Regulation of the PU.1 gene by distal elements

Li, Y., Okuno, Y., Zhang, P., Radomska, H. S., Chen, H.-M., Iwasaki, H., Akashi, K., Klemsz, M. J., McKercher, S. R., Maki, R. A., et al. (2001) · Blood

Genomics and Chromatin DynamicsHematopoietic Stem Cell Transplantation

Cited by 110

Stimulation of macrophages by lipopolysaccharide alters the phosphorylation state, conformation, and function of PU.1 via activation of casein kinase II

Lodie, T. A., Savedra, R., Golenbock, D. T., Van Beveren, C. P., Maki, R. A., & Fenton, M. J. (1997) · The Journal of Immunology

Immune Response and InflammationNF-κB Signaling Pathways

Cited by 106

Activation of Transcription by PU.1 Requires both Acidic and Glutamine Domains

Klemsz, M. J., & Maki, R. A. (1996) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsT-cell and B-cell Immunology

Cited by 93

Use of RDA analysis of knockout mice to identify myeloid genes regulated in vivo by PU.1 and C/EBP

Iwama, A., Zhang, P., Darlington, G. J., McKercher, S. R., Maki, R., & Tenen, D. G. (1998) · Nucleic Acids Research

Genomics and Chromatin DynamicsHematopoietic Stem Cell Transplantation

Cited by 91

New Insights on DNA Recognition by ets Proteins from the Crystal Structure of the PU.1 ETS Domain-DNA Complex

Pio, F., Kodandapani, R., Ni, C.-Z., Shepard, W., Klemsz, M., McKercher, S. R., Maki, R. A., & Ely, K. R. (1996) · Journal of Biological Chemistry

Genomics and Chromatin DynamicsProtein Structure and Dynamics

Cited by 81

Identification of differentially expressed genes induced by transient ischemic stroke

Schwarz, D. A., Barry, G., Mackay, K. B., Manu, F., Naeve, G. S., Vana, A. M., Verge, G., Conlon, P. J., Foster, A. C., & Maki, R. A. (2002) · Molecular Brain Research

Neuroinflammation and Neurodegeneration MechanismsAcute Ischemic Stroke Management

Cited by 65

Mutants of ETS domain PU.1 and GGAA/T recognition: Free energies and kinetics

Pio, F., Assa‐Munt, N., Yguerabide, J., & Maki, R. A. (1999) · Protein Science

DNA and Nucleic Acid ChemistryDiffusion and Search Dynamics

Cited by 22

Eosinophilopoiesis

ACKERMAN, S. J., DU, J., XIN, F., DEKOTER, R., MCKERCHER, S., MAKI, R., SINGH, H., & YAMAGUCHI, Y. (2000) · Respiratory Medicine

Asthma and respiratory diseasesGenomics and Chromatin Dynamics

Cited by 8