Heintz, Nathaniel

The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain

Kriaucionis, S., & Heintz, N. (2009) · Science

Epigenetics and DNA MethylationRNA modifications and cancer

Cited by 2,700

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

Yue, Z., Jin, S., Yang, C., Levine, A. J., & Heintz, N. (2003) · Proceedings of the National Academy of Sciences

Autophagy in Disease and TherapyCancer-related Molecular Pathways

Cited by 2,116

A gene expression atlas of the central nervous system based on bacterial artificial chromosomes

Gong, S., Zheng, C., Doughty, M. L., Losos, K., Didkovsky, N., Schambra, U. B., Nowak, N. J., Joyner, A., Leblanc, G., Hatten, M. E., et al. (2003) · Nature

Developmental Biology and Gene RegulationNeurogenesis and neuroplasticity mechanisms

Cited by 2,108

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

Chao, H.-T., Chen, H., Samaco, R. C., Xue, M., Chahrour, M., Yoo, J., Neul, J. L., Gong, S., Lu, H.-C., Heintz, N., et al. (2010) · Nature

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 1,168

A translational profiling approach for the molecular characterization of CNS cell types

Heiman, M., Schaefer, A., Gong, S., Peterson, J. D., Day, M., Ramsey, K. E., Suárez-Fariñas, M., Schwarz, C., Stephan, D. A., Surmeier, D. J., et al. (2008) · Cell

RNA and protein synthesis mechanismsNeuroscience and Neuropharmacology Research

Cited by 1,134

Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1–phosphatidylinositol-3-kinase complex

Zhong, Y., Wang, Q. J., Li, X., Yan, Y., Backer, J. M., Chait, B. T., Heintz, N., & Yue, Z. (2009) · Nature Cell Biology

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 1,005

Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs

Gong, S., Doughty, M., Harbaugh, C. R., Cummins, A., Hatten, M. E., Heintz, N., & Gerfen, C. R. (2007) · The Journal of Neuroscience

Animal Genetics and ReproductionVirus-based gene therapy research

Cited by 977

MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system

Mellén, M., Ayata, P., Dewell, S., Kriaucionis, S., & Heintz, N. (2012) · Cell

Epigenetics and DNA MethylationGenetics and Neurodevelopmental Disorders

Cited by 943

Application of a translational profiling approach for the comparative analysis of CNS cell types

Doyle, J. P., Dougherty, J. D., Heiman, M., Schmidt, E. F., Stevens, T. R., Ma, G., Bupp, S., Shrestha, P., Shah, R. D., Doughty, M. L., et al. (2008) · Cell

Single-cell and spatial transcriptomicsRNA and protein synthesis mechanisms

Cited by 912

GENSAT BAC cre-recombinase driver lines to study the functional organization of cerebral cortical and basal ganglia circuits

Gerfen, C. R., Paletzki, R., & Heintz, N. (2013) · Neuron

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 647

Neurodegeneration in Lurcher mice caused by mutation in δ2 glutamate receptor gene

Zuo, J., De Jager, P. L., Takahashi, K. A., Jiang, W., Linden, D. J., & Heintz, N. (1997) · Nature

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 554

Homologous recombination based modification in Esherichia coli and germline transmission in transgenic mice of a bacterial artificial chromsome

Yang, X. W., Model, P., & Heintz, N. (1997) · Nature Biotechnology

Animal Genetics and ReproductionCRISPR and Genetic Engineering

Cited by 544

Cell type–specific mRNA purification by translating ribosome affinity purification (TRAP)

Heiman, M., Kulicke, R., Fenster, R. J., Greengard, P., & Heintz, N. (2014) · Nature Protocols

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 498

The Cellular and Synaptic Architecture of the Mechanosensory Dorsal Horn

Abraira, V. E., Kuehn, E. D., Chirila, A. M., Springel, M. W., Toliver, A. A., Zimmerman, A. L., Orefice, L. L., Boyle, K. A., Bai, L., Song, B. J., et al. (2017) · Cell

Tactile and Sensory InteractionsPain Mechanisms and Treatments

Cited by 409

Lynx1, a Cholinergic Brake, Limits Plasticity in Adult Visual Cortex

Morishita, H., Miwa, J. M., Heintz, N., & Hensch, T. K. (2010) · Science

Neuroscience and Neuropharmacology ResearchNicotinic Acetylcholine Receptors Study

Cited by 365

Gene Expression Nervous System Atlas (GENSAT)

Heintz, N. (2004) · Nature Neuroscience

Single-cell and spatial transcriptomicsDevelopmental Biology and Gene Regulation

Cited by 323

Control of Stress-Induced Persistent Anxiety by an Extra-Amygdala Septohypothalamic Circuit

Anthony, T. E., Dee, N., Bernard, A., Lerchner, W., Heintz, N., & Anderson, D. J. (2014) · Cell

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 310

Induction of Autophagy in Axonal Dystrophy and Degeneration

Wang, Q. J., Ding, Y., Kohtz, S., Mizushima, N., Cristea, I. M., Rout, M. P., Chait, B. T., Zhong, Y., Heintz, N., & Yue, Z. (2006) · The Journal of Neuroscience

Autophagy in Disease and TherapyNeuroinflammation and Neurodegeneration Mechanisms

Cited by 308

A Novel Protein Complex Linking the δ2 Glutamate Receptor and Autophagy

Yue, Z., Horton, A., Bravin, M., DeJager, P. L., Selimi, F., & Heintz, N. (2002) · Neuron

Autophagy in Disease and TherapyNeuroscience and Neuropharmacology Research

Cited by 306

Minimal aberrant behavioral phenotypes of neuroligin‐3 R451C knockin mice

Chadman, K. K., Gong, S., Scattoni, M. L., Boltuck, S. E., Gandhy, S. U., Heintz, N., & Crawley, J. N. (2008) · Autism Research

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 292

Oxytocin modulates female sociosexual behavior through a specific class of prefrontal cortical interneurons

Nakajima, M., Görlich, A., & Heintz, N. (2014) · Cell

Neuroendocrine regulation and behaviorOlfactory and Sensory Function Studies

Cited by 262

A Cortical Circuit for Sexually Dimorphic Oxytocin-Dependent Anxiety Behaviors

Li, K., Nakajima, M., Ibañez-Tallon, I., & Heintz, N. (2016) · Cell

Neuroendocrine regulation and behaviorNeuropeptides and Animal Physiology

Cited by 234

Cell type–specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs

Bateup, H. S., Svenningsson, P., Kuroiwa, M., Gong, S., Nishi, A., Heintz, N., & Greengard, P. (2008) · Nature Neuroscience

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 233

Novel Modulation of Neuronal Nicotinic Acetylcholine Receptors by Association with the Endogenous Prototoxin lynx1

Ibañez-Tallon, I., Miwa, J. M., Wang, H.-L., Adams, N. C., Crabtree, G. W., Sine, S. M., & Heintz, N. (2002) · Neuron

Nicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology Research

Cited by 200