Wallace, Chris

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

The Wellcome Trust Case Control Consortium, Management Committee, Burton, P. R., Clayton, D. G., Cardon, L. R., Craddock, N., Deloukas, P., Duncanson, A., Kwiatkowski, D. P., McCarthy, M. I., et al. (2007) · Nature

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 9,442

Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics

Giambartolomei, C., Vukcevic, D., Schadt, E. E., Franke, L., Hingorani, A. D., Wallace, C., & Plagnol, V. (2014) · PLoS Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 4,261

Mendelian randomization

Sanderson, E., Glymour, M. M., Holmes, M. V., Kang, H., Morrison, J., Munafò, M. R., Palmer, T., Schooling, C. M., Wallace, C., Zhao, Q., et al. (2022) · Nature Reviews Methods Primers

Genetic Associations and EpidemiologyAdvanced Causal Inference Techniques

Cited by 2,229

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

Finland, G. O. T. 1. D. I., Todd, J. A., the Wellcome Trust Case Control Consortium, Walker, N. M., Cooper, J. D., Smyth, D. J., Downes, K., Plagnol, V., Bailey, R., Nejentsev, S., et al. (2007) · Nature Genetics

Diabetes and associated disordersGenetic Associations and Epidemiology

Cited by 1,456

Common variants near MC4R are associated with fat mass, weight and risk of obesity

The Prostate, L., Loos, R. J. F., KORA, Study, N. H., Initiative, D. G., Study, T. S., The Wellcome Trust Case Control Consortium, FUSION, Lindgren, C. M., Li, S., et al. (2008) · Nature Genetics

Genetic Associations and EpidemiologyRegulation of Appetite and Obesity

Cited by 1,325

Genome-wide association study identifies eight loci associated with blood pressure

Wellcome Trust Case Control Consortium, Newton-Cheh, C., Johnson, T., Gateva, V., Tobin, M. D., Bochud, M., Coin, L., Najjar, S. S., Zhao, J. H., Heath, S. C., et al. (2009) · Nature Genetics

Genetic Associations and EpidemiologyBlood Pressure and Hypertension Studies

Cited by 1,215

Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters

Javierre, B. M., Burren, O. S., Wilder, S. P., Kreuzhuber, R., Hill, S. M., Sewitz, S., Cairns, J., Wingett, S. W., Várnai, C., Thiecke, M. J., et al. (2016) · Cell

Genomics and Chromatin DynamicsGenetic Associations and Epidemiology

Cited by 1,046

Genome-wide association analysis identifies 20 loci that influence adult height

Initiative, D. G., Weedon, M. N., The Wellcome Trust Case Control Consortium, Cambridge GEM Consortium, Lango, H., Lindgren, C. M., Wallace, C., Evans, D. M., Mangino, M., Freathy, R. M., et al. (2008) · Nature Genetics

Genetic Associations and EpidemiologyGenetics and Physical Performance

Cited by 826

Pervasive Sharing of Genetic Effects in Autoimmune Disease

Cotsapas, C., Voight, B. F., Rossin, E., Lage, K., Neale, B. M., Wallace, C., Abecasis, G. R., Barrett, J. C., Behrens, T., Cho, J., et al. (2011) · PLoS Genetics

Genetic Associations and EpidemiologyMultiple Sclerosis Research Studies

Cited by 606

A more accurate method for colocalisation analysis allowing for multiple causal variants

Wallace, C. (2021) · PLOS Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 567

Combining evidence from Mendelian randomization and colocalization: Review and comparison of approaches

Zuber, V., Grinberg, N. F., Gill, D., Manipur, I., Slob, E. A. W., Patel, A., Wallace, C., & Burgess, S. (2022) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 532

Eliciting priors and relaxing the single causal variant assumption in colocalisation analyses

Wallace, C. (2020) · PLOS Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 441

Tryptophan depletion impairs stimulus-reward learning while methylphenidate disrupts attentional control in healthy young adults: implications for the monoaminergic basis of impulsive behaviour

Rogers, R. D., Blackshaw, A. J., Middleton, H. C., Matthews, K., Hawtin, K., Crowley, C., Hopwood, A., Wallace, C., Deakin, J. F. W., Sahakian, B. J., et al. (1999) · Psychopharmacology

Neurotransmitter Receptor Influence on BehaviorNeural and Behavioral Psychology Studies

Cited by 289

A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk

Cardiogenics Consortium, Heinig, M., Petretto, E., Wallace, C., Bottolo, L., Rotival, M., Lu, H., Li, Y., Sarwar, R., Langley, S. R., et al. (2010) · Nature

Diabetes and associated disordersGenetic Associations and Epidemiology

Cited by 283

Inherited Variation in Vitamin D Genes Is Associated With Predisposition to Autoimmune Disease Type 1 Diabetes

Cooper, J. D., Smyth, D. J., Walker, N. M., Stevens, H., Burren, O. S., Wallace, C., Greissl, C., Ramos-Lopez, E., Hyppönen, E., Dunger, D. B., et al. (2011) · Diabetes

Vitamin D Research StudiesDiabetes and associated disorders

Cited by 279

Capture Hi-C reveals novel candidate genes and complex long-range interactions with related autoimmune risk loci

Martin, P., McGovern, A., Orozco, G., Duffus, K., Yarwood, A., Schoenfelder, S., Cooper, N. J., Barton, A., Wallace, C., Fraser, P., et al. (2015) · Nature Communications

Genomics and Chromatin DynamicsGenetic Associations and Epidemiology

Cited by 213

Statistical Testing of Shared Genetic Control for Potentially Related Traits

Wallace, C. (2013) · Genetic Epidemiology

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 115

Chromosome contacts in activated T cells identify autoimmune disease candidate genes

Burren, O. S., Rubio García, A., Javierre, B.-M., Rainbow, D. B., Cairns, J., Cooper, N. J., Lambourne, J. J., Schofield, E., Castro Dopico, X., Ferreira, R. C., et al. (2017) · Genome Biology

Genomics and Chromatin DynamicsGenetic Associations and Epidemiology

Cited by 80

Epigenetic analysis of regulatory T cells using multiplex bisulfite sequencing

Rainbow, D. B., Yang, X., Burren, O., Pekalski, M. L., Smyth, D. J., Klarqvist, M. D. R., Penkett, C. J., Brugger, K., Martin, H., Todd, J. A., et al. (2015) · European Journal of Immunology

T-cell and B-cell ImmunologyEpigenetics and DNA Methylation

Cited by 26

Functional effects of variation in transcription factor binding highlight long-range gene regulation by epromoters

Mitchelmore, J., Grinberg, N. F., Wallace, C., & Spivakov, M. (2020) · Nucleic Acids Research

Genomics and Chromatin DynamicsGenetic Associations and Epidemiology

Cited by 25