Spee, Bart

Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease

Boulter, L., Govaere, O., Bird, T. G., Radulescu, S., Ramachandran, P., Pellicoro, A., Ridgway, R. A., Seo, S. S., Spee, B., Van Rooijen, N., et al. (2012) · Nature Medicine

Liver physiology and pathologyWnt/β-catenin signaling in development and cancer

Cited by 747

Characterisation of the liver progenitor cell niche in liver diseases: potential involvement of Wnt and Notch signalling

Spee, B., Carpino, G., Schotanus, B. A., Katoonizadeh, A., Borght, S. V., Gaudio, E., & Roskams, T. (2010) · Gut

Liver physiology and pathologyLiver Diseases and Immunity

Cited by 208

Large‐Scale Production of LGR5‐Positive Bipotential Human Liver Stem Cells

Schneeberger, K., Sánchez‐Romero, N., Ye, S., van Steenbeek, F. G., Oosterhoff, L. A., Pla Palacin, I., Chen, C., van Wolferen, M. E., van Tienderen, G., Lieshout, R., et al. (2020) · Hepatology

Liver physiology and pathologyTissue Engineering and Regenerative Medicine

Cited by 141

Hydrogels for Liver Tissue Engineering

Ye, S., Boeter, J. W. B., Penning, L. C., Spee, B., & Schneeberger, K. (2019) · Bioengineering

Hydrogels: synthesis, properties, applicationsTissue Engineering and Regenerative Medicine

Cited by 112

Hydrogels derived from decellularized liver tissue support the growth and differentiation of cholangiocyte organoids

Willemse, J., van Tienderen, G., van Hengel, E., Schurink, I., van der Ven, D., Kan, Y., de Ruiter, P., Rosmark, O., Westergren-Thorsson G, G., Schneeberger, K., et al. (2022) · Biomaterials

Tissue Engineering and Regenerative Medicine3D Printing in Biomedical Research

Cited by 106

Converging biofabrication and organoid technologies: the next frontier in hepatic and intestinal tissue engineering?

Schneeberger, K., Spee, B., Costa, P., Sachs, N., Clevers, H., & Malda, J. (2017) · Biofabrication

3D Printing in Biomedical ResearchTissue Engineering and Regenerative Medicine

Cited by 100

Human extrahepatic and intrahepatic cholangiocyte organoids show region-specific differentiation potential and model cystic fibrosis-related bile duct disease

Verstegen, M. M. A., Roos, F. J. M., Burka, K., Gehart, H., Jager, M., de Wolf, M., Bijvelds, M. J. C., de Jonge, H. R., Ardisasmita, A. I., van Huizen, N. A., et al. (2020) · Scientific Reports

Pediatric Hepatobiliary Diseases and TreatmentsLiver physiology and pathology

Cited by 86

A hollow fiber membrane-based liver organoid-on-a-chip model for examining drug metabolism and transport

Myszczyszyn, A., Muench, A., Lehmann, V., Sinnige, T., van Steenbeek, F. G., Bouwmeester, M., Samsom, R.-A., Keuper-Navis, M., van der Made, T. K., Kogan, D., et al. (2025) · Biofabrication

3D Printing in Biomedical ResearchDrug Transport and Resistance Mechanisms

Cited by 14

Cholangiocyte organoids to study drug-induced injury

Wang, Z., Xing, C., van der Laan, L. J. W., Verstegen, M. M. A., Spee, B., & Masereeuw, R. (2024) · Stem Cell Research & Therapy

Drug-Induced Hepatotoxicity and ProtectionDrug Transport and Resistance Mechanisms

Cited by 13