Kupka, Ralph

Genome-wide association study identifies 30 loci associated with bipolar disorder

eQTLGen Consortium, Stahl, E. A., BIOS Consortium, the Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Breen, G., Forstner, A. J., McQuillin, A., Ripke, S., Trubetskoy, V., Mattheisen, M., et al. (2019) · Nature Genetics

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 1,519

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

Mullins, N., Forstner, A. J., O’Connell, K. S., Coombes, B., Coleman, J. R. I., Qiao, Z., Als, T. D., Bigdeli, T. B., Børte, S., Bryois, J., et al. (2021) · Nature Genetics

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 1,517

Morbidity in 258 Bipolar Outpatients Followed for 1 Year With Daily Prospective Ratings on the NIMH Life Chart Method

Post, R. M., Denicoff, K. D., Leverich, G. S., Altshuler, L. L., Frye, M. A., Suppes, T. M., Rush, A. J., Keck, P. E., McElroy, S. L., Luckenbaugh, D. A., et al. (2003) · The Journal of Clinical Psychiatry

Bipolar Disorder and TreatmentPersonality Disorders and Psychopathology

Cited by 418

Three times more days depressed than manic or hypomanic in both bipolar I and bipolar II disorder 1

Kupka, R. W., Altshuler, L. L., Nolen, W. A., Suppes, T., Luckenbaugh, D. A., Leverich, G. S., Frye, M. A., Keck, P. E., McElroy, S. L., Grunze, H., et al. (2007) · Bipolar Disorders

Bipolar Disorder and TreatmentMental Health Research Topics

Cited by 397

Early-Onset Bipolar Disorder and Treatment Delay Are Risk Factors for Poor Outcome in Adulthood

Post, R. M., Leverich, G. S., Kupka, R. W., Keck, P. E., McElroy, S. L., Altshuler, L. L., Frye, M. A., Luckenbaugh, D. A., Rowe, M., Grunze, H., et al. (2010) · The Journal of Clinical Psychiatry

Bipolar Disorder and TreatmentPersonality Disorders and Psychopathology

Cited by 360

Mood switch in bipolar depression: comparison of adjunctive venlafaxine, bupropion and sertraline

Post, R. M., Altshuler, L. L., Leverich, G. S., Frye, M. A., Nolen, W. A., Kupka, R. W., Suppes, T., McElroy, S., Keck, P. E., Denicoff, K. D., et al. (2006) · British Journal of Psychiatry

Bipolar Disorder and TreatmentTreatment of Major Depression

Cited by 350

A Discriminating Messenger RNA Signature for Bipolar Disorder Formed by an Aberrant Expression of Inflammatory Genes in Monocytes

Padmos, R. C., Hillegers, M. H. J., Knijff, E. M., Vonk, R., Bouvy, A., Staal, F. J. T., de Ridder, D., Kupka, R. W., Nolen, W. A., & Drexhage, H. A. (2008) · Archives of General Psychiatry

Bipolar Disorder and TreatmentTryptophan and brain disorders

Cited by 336

Impact of Antidepressant Discontinuation After Acute Bipolar Depression Remission on Rates of Depressive Relapse at 1-Year Follow-Up

Altshuler, L., Suppes, T., Black, D., Nolen, W. A., Keck, P. E., Frye, M. A., McElroy, S., Kupka, R., Grunze, H., Walden, J., et al. (2003) · American Journal of Psychiatry

Bipolar Disorder and TreatmentTreatment of Major Depression

Cited by 287

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

Mullins, N., Kang, J., Campos, A. I., Coleman, J. R. I., Edwards, A. C., Galfalvy, H., Levey, D. F., Lori, A., Shabalin, A., Starnawska, A., et al. (2022) · Biological Psychiatry

Suicide and Self-Harm StudiesGenetic Associations and Epidemiology

Cited by 238

Double-Blind, Randomized, Placebo-Controlled Trials of Ethyl-Eicosapentanoate in the Treatment of Bipolar Depression and Rapid Cycling Bipolar Disorder

Keck, P. E., Mintz, J., McElroy, S. L., Freeman, M. P., Suppes, T., Frye, M. A., Altshuler, L. L., Kupka, R., Nolen, W. A., Leverich, G. S., et al. (2006) · Biological Psychiatry

Bipolar Disorder and TreatmentFatty Acid Research and Health

Cited by 234

Staging systems in bipolar disorder: an International Society for Bipolar Disorders Task Force Report

Kapczinski, F., Magalhães, P. V. S., Balanzá‐Martinez, V., Dias, V. V., Frangou, S., Gama, C. S., Gonzalez‐Pinto, A., Grande, I., Ha, K., Kauer‐Sant'Anna, M., et al. (2014) · Acta Psychiatrica Scandinavica

Bipolar Disorder and TreatmentPersonality Disorders and Psychopathology

Cited by 217

Mixed Hypomania in 908 Patients With Bipolar Disorder Evaluated Prospectively in the Stanley Foundation Bipolar Treatment Network: A Sex-Specific Phenomenon

Suppes, T., Mintz, J., McElroy, S. L., Altshuler, L. L., Kupka, R. W., Frye, M. A., Keck, P. E., Nolen, W. A., Leverich, G. S., Grunze, H., et al. (2005) · Archives of General Psychiatry

Bipolar Disorder and TreatmentPersonality Disorders and Psychopathology

Cited by 209

Rapid and Non-Rapid Cycling Bipolar Disorder: A Meta-Analysis of Clinical Studies

Kupka, R. W., Luckenbaugh, D. A., Post, R. M., Leverich, G. S., & Nolen, W. A. (2003) · The Journal of Clinical Psychiatry

Bipolar Disorder and TreatmentPersonality Disorders and Psychopathology

Cited by 168

What is the optimal serum level for lithium in the maintenance treatment of bipolar disorder? A systematic review and recommendations from the ISBD/IGSLI Task Force on treatment with lithium

Nolen, W. A., Licht, R. W., Young, A. H., Malhi, G. S., Tohen, M., Vieta, E., Kupka, R. W., Zarate, C., Nielsen, R. E., Baldessarini, R. J., et al. (2019) · Bipolar Disorders

Bipolar Disorder and TreatmentSchizophrenia research and treatment

Cited by 164

Prevalence and correlates of eating disorders in 875 patients with bipolar disorder

McElroy, S. L., Frye, M. A., Hellemann, G., Altshuler, L., Leverich, G. S., Suppes, T., Keck, P. E., Nolen, W. A., Kupka, R., & Post, R. M. (2011) · Journal of Affective Disorders

Eating Disorders and BehaviorsBipolar Disorder and Treatment

Cited by 162

Psychological interventions for adults with bipolar disorder: systematic review and meta-analysis

Oud, M., Mayo-Wilson, E., Braidwood, R., Schulte, P., Jones, S. H., Morriss, R., Kupka, R., Cuijpers, P., & Kendall, T. (2016) · British Journal of Psychiatry

Bipolar Disorder and TreatmentPersonality Disorders and Psychopathology

Cited by 144

The prevalence and management of side effects of lithium and anticonvulsants as mood stabilizers in bipolar disorder from a clinical perspective: a review

Dols, A., Sienaert, P., van Gerven, H., Schouws, S., Stevens, A., Kupka, R., & Stek, M. L. (2013) · International Clinical Psychopharmacology

Bipolar Disorder and TreatmentSchizophrenia research and treatment

Cited by 86

Discontinuation of psychotropic medication: a synthesis of evidence across medication classes.

Vinkers, C. H., Kupka, R. W., Penninx, B. W., Ruhé, H. G., van Gaalen, J. M., van Haaren, P. C. F., Schellekens, A. F. A., Jauhar, S., Ramos-Quiroga, J. A., Vieta, E., et al. (2024) · Molecular Psychiatry

Treatment of Major DepressionBipolar Disorder and Treatment

Cited by 51

The relationship between self-reported borderline personality features and prospective illness course in bipolar disorder

Riemann, G., Weisscher, N., Post, R. M., Altshuler, L., McElroy, S., Frye, M. A., Keck, P. E., Leverich, G. S., Suppes, T., Grunze, H., et al. (2017) · International Journal of Bipolar Disorders

Bipolar Disorder and TreatmentPersonality Disorders and Psychopathology

Cited by 28

Referral of patients to psychiatric emergency departments by police: A systematic review and meta-analysis

Goldschmidt, T., Bermpohl, F., Schreiter, S., van Bergen, A. H., Kupka, R. W., Schouler-Ocak, M., Gutwinski, S., & Deutscher, K. (2025) · Psychiatric Services

Psychiatric care and mental health servicesEmergency and Acute Care Studies

Cited by 2