Shuler, Michael L.

A guide to the organ-on-a-chip

Leung, C. M., de Haan, P., Ronaldson-Bouchard, K., Kim, G.-A., Ko, J., Rho, H. S., Chen, Z., Habibovic, P., Jeon, N. L., Takayama, S., et al. (2022) · Nature Reviews Methods Primers

3D Printing in Biomedical ResearchMicrofluidic and Capillary Electrophoresis Applications

Cited by 1,116

Multi-Organ toxicity demonstration in a functional human in vitro system composed of four organs

Oleaga, C., Bernabini, C., Smith, A. S. T., Srinivasan, B., Jackson, M., McLamb, W., Platt, V., Bridges, R., Cai, Y., Santhanam, N., et al. (2016) · Scientific Reports

3D Printing in Biomedical ResearchTissue Engineering and Regenerative Medicine

Cited by 442

Body-on-a-chip simulation with gastrointestinal tract and liver tissues suggests that ingested nanoparticles have the potential to cause liver injury

Esch, M. B., Mahler, G. J., Stokol, T., & Shuler, M. L. (2014) · Lab Chip

Nanoparticles: synthesis and applicationsNanoparticle-Based Drug Delivery

Cited by 281

Recent Advances in Body-on-a-Chip Systems

Sung, J. H., Wang, Y. I., Narasimhan Sriram, N., Jackson, M., Long, C., Hickman, J. J., & Shuler, M. L. (2019) · Analytical Chemistry

3D Printing in Biomedical ResearchMicrofluidic and Capillary Electrophoresis Applications

Cited by 268

Multi-organ system for the evaluation of efficacy and off-target toxicity of anticancer therapeutics

McAleer, C. W., Long, C. J., Elbrecht, D., Sasserath, T., Bridges, L. R., Rumsey, J. W., Martin, C., Schnepper, M., Wang, Y., Schuler, F., et al. (2019) · Science Translational Medicine

3D Printing in Biomedical ResearchMicrofluidic and Capillary Electrophoresis Applications

Cited by 199

Multi-cellular 3D human primary liver cell culture elevates metabolic activity under fluidic flow

Esch, M. B., Prot, J.-M., Wang, Y. I., Miller, P., Llamas-Vidales, J. R., Naughton, B. A., Applegate, D. R., & Shuler, M. L. (2015) · Lab on a Chip

3D Printing in Biomedical ResearchLiver physiology and pathology

Cited by 173

Strategies for using mathematical modeling approaches to design and interpret multi-organ microphysiological systems (MPS)

Sung, J. H., Wang, Y., & Shuler, M. L. (2019) · APL Bioengineering

3D Printing in Biomedical ResearchMicrofluidic and Capillary Electrophoresis Applications

Cited by 66

Self-contained, low-cost Body-on-a-Chip systems for drug development

Wang, Y. I., Oleaga, C., Long, C. J., Esch, M. B., McAleer, C. W., Miller, P. G., Hickman, J. J., & Shuler, M. L. (2017) · Experimental Biology and Medicine

3D Printing in Biomedical ResearchTissue Engineering and Regenerative Medicine

Cited by 59

Organ-, body-and disease-on-a-chip systems

Shuler, M. L. (2017) · Lab on a Chip

3D Printing in Biomedical ResearchMicrofluidic and Capillary Electrophoresis Applications

Cited by 54

Incorporating genome-wide DNA sequence information into a dynamic whole-cell model of Escherichia coli : application to DNA replication

Atlas, J. C., Nikolaev, E. V., Browning, S. T., & Shuler, M. L. (2008) · IET Systems Biology

Gene Regulatory Network AnalysisBacterial Genetics and Biotechnology

Cited by 31

Robust control of initiation of prokaryotic chromosome replication: essential considerations for a minimal cell

Browning, S. T., Castellanos, M., & Shuler, M. L. (2004) · Biotechnology and Bioengineering

Gene Regulatory Network AnalysisBacterial Genetics and Biotechnology

Cited by 26