Sprengel, Rolf

Heteromeric NMDA receptors: molecular and functional distinction of subtypes

Monyer, H., Sprengel, R., Schoepfer, R., Herb, A., Higuchi, M., Lomeli, H., Burnashev, N., Sakmann, B., & Seeburg, P. H. (1992) · Science

Neuroscience and Neuropharmacology ResearchAmino Acid Enzymes and Metabolism

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Encoding of conditioned fear in central amygdala inhibitory circuits

Ciocchi, S., Herry, C., Grenier, F., Wolff, S. B. E., Letzkus, J. J., Vlachos, I., Ehrlich, I., Sprengel, R., Deisseroth, K., Stadler, M. B., et al. (2010) · Nature

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 924

Importance of AMPA Receptors for Hippocampal Synaptic Plasticity But Not for Spatial Learning

Zamanillo, D., Sprengel, R., Hvalby, Ø., Jensen, V., Burnashev, N., Rozov, A., Kaiser, K. M. M., Köster, H. J., Borchardt, T., Worley, P., et al. (1999) · Science

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 791

Hippocampal synaptic plasticity, spatial memory and anxiety

Bannerman, D. M., Sprengel, R., Sanderson, D. J., McHugh, S. B., Rawlins, J. N. P., Monyer, H., & Seeburg, P. H. (2014) · Nature Reviews Neuroscience

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 688

Subunit Composition of Synaptic AMPA Receptors Revealed by a Single-Cell Genetic Approach

Lu, W., Shi, Y., Jackson, A. C., Bjorgan, K., During, M. J., Sprengel, R., Seeburg, P. H., & Nicoll, R. A. (2009) · Neuron

Neuroscience and Neuropharmacology ResearchReceptor Mechanisms and Signaling

Cited by 660

Mutations in the SHANK2 synaptic scaffolding gene in autism spectrum disorder and mental retardation

Berkel, S., Marshall, C. R., Weiss, B., Howe, J., Roeth, R., Moog, U., Endris, V., Roberts, W., Szatmari, P., Pinto, D., et al. (2010) · Nature Genetics

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 563

A new population of parvocellular oxytocin neurons controlling magnocellular neuron activity and inflammatory pain processing

Eliava, M., Melchior, M., Knobloch-Bollmann, H. S., Wahis, J., da Silva Gouveia, M., Tang, Y., Ciobanu, A. C., Triana del Rio, R., Roth, L. C., Althammer, F., et al. (2016) · Neuron

Pain Mechanisms and TreatmentsNeuroendocrine regulation and behavior

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Strain Differences in Stress Responsivity Are Associated with Divergent Amygdala Gene Expression and Glutamate-Mediated Neuronal Excitability

Mozhui, K., Karlsson, R.-M., Kash, T. L., Ihne, J., Norcross, M., Patel, S., Farrell, M. R., Hill, E. E., Graybeal, C., Martin, K. P., et al. (2010) · The Journal of Neuroscience

Stress Responses and CortisolNeuroscience and Neuropharmacology Research

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Single-spike detection in vitro and in vivo with a genetic Ca2+ sensor

Wallace, D. J., zum Alten Borgloh, S. M., Astori, S., Yang, Y., Bausen, M., Kügler, S., Palmer, A. E., Tsien, R. Y., Sprengel, R., Kerr, J. N. D., et al. (2008) · Nature Methods

Advanced Fluorescence Microscopy TechniquesNeuroscience and Neuropharmacology Research

Cited by 191

Inherited and de novo SHANK2 variants associated with autism spectrum disorder impair neuronal morphogenesis and physiology

Berkel, S., Tang, W., Treviño, M., Vogt, M., Obenhaus, H. A., Gass, P., Scherer, S. W., Sprengel, R., Schratt, G., & Rappold, G. A. (2012) · Human Molecular Genetics

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 162

AMPA receptor subunit 1 (GluR‐A) knockout mice model the glutamate hypothesis of depression

Chourbaji, S., Vogt, M. A., Fumagalli, F., Sohr, R., Frasca, A., Brandwein, C., Hörtnagl, H., Riva, M. A., Sprengel, R., & Gass, P. (2008) · The FASEB Journal

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 144

Silencing and un-silencing of tetracycline-controlled genes in neurons

Zhu, P., Aller, M. I., Baron, U., Cambridge, S., Bausen, M., Herb, J., Sawinski, J., Cetin, A., Osten, P., Nelson, M. L., et al. (2007) · PLoS ONE

Bacterial Genetics and BiotechnologyGene Regulatory Network Analysis

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The death receptor CD95 activates adult neural stem cells for working memory formation and brain repair

Corsini, N. S., Sancho-Martinez, I., Laudenklos, S., Glagow, D., Kumar, S., Letellier, E., Koch, P., Teodorczyk, M., Kleber, S., Klussmann, S., et al. (2009) · Cell Stem Cell

Neurogenesis and neuroplasticity mechanismsNeuroinflammation and Neurodegeneration Mechanisms

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The NMDA Receptor Channel: Molecular Design of a Coincidence Detector

SEEBURG, P. H., BURNASHEV, N., KÖHR, G., KUNER, T., SPRENGEL, R., & MONYER, H. (1995) · Proceedings of the 1993 Laurentian Hormone Conference

Neuroscience and Neuropharmacology ResearchNicotinic Acetylcholine Receptors Study

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Motor Learning Requires Purkinje Cell Synaptic Potentiation through Activation of AMPA-Receptor Subunit GluA3

Gutierrez-Castellanos, N., Da Silva-Matos, C. M., Zhou, K., Canto, C. B., Renner, M. C., Koene, L. M. C., Ozyildirim, O., Sprengel, R., Kessels, H. W., & De Zeeuw, C. I. (2017) · Neuron

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

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Sex Hormones Regulate SHANK Expression

Berkel, S., Eltokhi, A., Fröhlich, H., Porras-Gonzalez, D., Rafiullah, R., Sprengel, R., & Rappold, G. A. (2018) · Frontiers in Molecular Neuroscience

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

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Neural Basis of Benzodiazepine Reward: Requirement for α2 Containing GABAA Receptors in the Nucleus Accumbens

Engin, E., Bakhurin, K. I., Smith, K. S., Hines, R. M., Reynolds, L. M., Tang, W., Sprengel, R., Moss, S. J., & Rudolph, U. (2014) · Neuropsychopharmacology

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

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Imbalanced post- and extrasynaptic SHANK2A functions during development affect social behavior in SHANK2-mediated neuropsychiatric disorders

Eltokhi, A., Gonzalez-Lozano, M. A., Oettl, L.-L., Rozov, A., Pitzer, C., Röth, R., Berkel, S., Hüser, M., Harten, A., Kelsch, W., et al. (2021) · Molecular Psychiatry

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

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